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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • AEOL-induced NRF2 activation and DWORF overexpression mitigate myocardial I/R injury 
    Asensio-López, María-del-Carmen; Ruiz-Ballester, Miriam; Pascual-Oliver, Silvia; Bastida-Nicolás, Francisco-José; Sassi, Yassine; Fuster, José-Javier; Pascual-Figal, Domingo-Andrés; Soler, Fernando; Lax, Antonio (SPRINGER, 2025-05-15)
    BACKGROUND: The causal relationship between the activation of nuclear factor erythroid 2-related factor 2 (NRF2) and the preservation of SERCA2a function in mitigating myocardial ischemia-reperfusion (mI/R) injury, along ...
  • Severe Paediatric Asthma Collaborative in Europe: real-world data on children on biologics 
    Liu, Norrice-M; Pijnenburg, Marielle-W; Deschildre, Antoine; de-Mir-Messa, Inés; Adalen, Sigve; Amat, Flore; Antonino, Luna; Bierme, Priscille; Bravo-López, Maynor; Carlsen, Karin-C-L; Carraro, Silvia; Cros, Pierrick; Delestrain, Celine; Díaz-García, Carolina; Epaud, Ralph; Fenu, Grazia; Ferraro, Valentina-A; Fleming, Louise; Hanssens, Laurence; Heine, Anouk; Labouret, Geraldine; Leóni, María-Chiara; Licari, Amelia; Lombardi, Enrico; López-Neyra, Alejandro; Marguet, Christophe; Mazenq, Julie; Pérez-Tarazona, Santiago; Ramos-Díaz, Juan-Carlos; Schweitzer, Cyril; Spada, Elena; Valverde-Molina, José; Verhulst, Stijn; Wanin, Stephanie; Rusconi, Franca (EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2025-05)
    INTRODUCTION: Real-world data on children with severe asthma is scarce. We report characteristics of children with severe asthma already on biologics, enrolled in the Severe Paediatric Asthma Collaborative in Europe, a ...
  • Impact of environmental exposures on exhaled breath and lung function: NELA Birth Cohort 
    Sola-Martínez, Rosa-Alba; Jiménez-Guerrero, Pedro; Sánchez-Solís, Manuel; Lozano-Terol, Gema; Gallego-Jara, Julia; Martínez-Vivancos, Adrián; Morales, Eva; García-Marcos, Luis; de-Diego-Puente, Teresa (EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2025-01)
    INTRODUCTION: Exposure to environmental factors (i.e. air pollution and second-hand tobacco smoke) have been associated with impaired lung function. However, the impact of environmental factors on lung health is usually ...
  • Identification of 4 autophagy-related genetic variants as risk factors for chronic lymphocytic leukemia 
    Cabrera-Serrano, Antonio-José; Sánchez-Maldonado, José-Manuel; Rodríguez-Sevilla, Juan-José; Reyes-Zurita, Fernando-Jesús; Collado, Rosa; Puiggros, Anna; Cornejo-Calvo, Elena; García-Martin, Paloma; Ter-Horst, Rob; Benavente, Yolanda; Jerez-Cayuela, Andrés; Landi, Stefano; Espinet, Blanca; Maffei, Rossana; López-Nevot, Miguel-Ángel; Ramos-Campoy, Silvia; González-Olmedo, Carmen; Chen-Liang, Tzu-Hua; Moreno, Victor; Jannus, Fatin; Marcos-Gragera, Rafael; Carretero-Fernández, María; Sampaio-Marques, Belem; Gamez, Irene; García-Álvarez, María; Camp, Nicola-J; Dierssen-Sotos, Trinidad; Kamaso, Joanna; Pérez, Eva-María; Norman, Aaron-D; Luppi, Mario; Li, Yang; Alcoceba, Miguel; Campa, Daniele; de-San-Jose, Silvia; Marasca, Roberto; Ludovico, Paula; Clay-Gilmour, Alyssa; Canzian, Federico; Ibáñez, Marian; Netea, Mihai-G; McKay, James; Casabonne, Delphine; Berndt, Sonja-I; Slager, Susan-L; Sainz, Juan (ELSEVIER, 2025-12-09)
    We investigated the influence of 55 583 autophagy-related single-nucleotide polymorphisms (SNPs) on chronic lymphocytic leukemia (CLL) risk across 4 independent populations comprising 5472 CLL cases and 726 465 controls. ...
  • Tafasitamab plus lenalidomide as salvage therapy in diffuse large B-cell lymphoma: real-world experience from GELTAMO 
    Gutiérrez, Antonio; Zeberio, Izaskun; Peñalver, Francisco-Javier; Martínez-Barranco, Pilar; Pérez, Sandra; Morillo, Daniel; Martin, Xabier; Nicolás, Concepción; Ferrero, Ainara; Jiménez-Ubieto, Ana; Bastos-Oreiro, Mariana; Dávila-Valls, Julio; Calle, María-Victoria; Pérez, María; Rodríguez, Guillermo; Alonso, Aranzazu; García-Noblejas, Ana; Sánchez-Argüello, Diana; Knight, Teresa; Fernández, Ángeles; López, Javier; Pérez-de-Oteyza, Jaime; González-de-Villambrosia, Sonia; Pérez, Elena; Marín, Alejandro; Navarro, María-Belén; Fernández, Rubén; Gómez, Pilar; Hueso, José-Antonio; Peñarrubia-Ponce, María-Jesús; Bravo, Pilar; García-Belmonte, Daniel; de-la-Nuez, Haridian; Nistal, Sara; Abrisqueta, Pau; Iban, Fernanda; Palomera, Luis; Donato, Eva; Provencio, Andrea; Infante, María-Stefania; González-Barca, Eva (ELSEVIER, 2025-10-14)
    Relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) remains challenging to treat, especially in patients ineligible for intensive therapy or chimeric antigen receptor T cells. Tafasitamab plus lenalidomide (T/L) ...
  • Autologous stem cell transplantation for relapsed/refractory large B-cell lymphoma: a multicenter GETH-TC/GELTAMO study 
    Bento, Leyre; Gutiérrez, Antonio; Martínez, Carmen; Orti-Verdet, María-Consejo; Sorribes, Marina; Caballero, Ana-Carolina; Peña, Marta; Pérez, Ariadna; Jiménez-Ubieto, Ana; Medina, Lucía; Bastos-Oreiro, Mariana; Fernández-Caldas-González, Paula; Navarro, Belén; Salcedo, Isabel; Abrisqueta, Pau; Español-Morales, Ignacio; Cornago, Javier; Martín-Moro, Fernando; García, Lucía; Gómez, Pilar; Varela, María-Rosario; Puente, María; Zanabili, Joud; Zudaire, Teresa; Zeberio, Izaskun; del-Campo, Raquel; González, Leslie; González, Pedro; Blázquez, Cristina; Rovira, Jordina; Sitges, Marta; Franch-Sarto, Mireia; Cabero, Almudena; Mussetti, Alberto; Montoro, Juan; Sampol, Antonia; Sureda, Anna; Caballero, Dolores; Martín-García-Sancho, Alejandro (ELSEVIER, 2025-07-08)
    We performed a retrospective multicenter study including 791 patients with relapsed/refractory (R/R) large B-cell lymphoma (LBCL) who underwent autologous stem cell transplantation (ASCT). After a median follow-up of 74 ...
  • Clinical impact of [18F]FDG-PET/CT in ARI0002h treatment, a CAR-T against BCMA for relapsed/refractory multiple myeloma 
    Zugas, Inés; Tormo-Ratera, Marta; Oliver-Caldes, Aina; Soler-Perromat, Juan-Carlos; González-Calle, Veronica; Moreno, David-F; Cabanas-Perianes, Valentín; López-Muñoz, Nieves; Bartolome-Solanas, Álvaro; Español-Rego, Marta; Reguera-Ortega, Juan-Luis; Rosinol, Laura; López-Corral, Lucía; Tovar, Natalia; Rodríguez-Lobato, Luis-Gerardo; Álvarez-Pérez, Rosa-María; Varea, Sara; Olesti, Eulalia; Gómez-Grande, Adolfo; Frutos-Esteban, Laura; Tamayo, Pilar; Juan, Manel; Moraleda-Jiménez, José-María; Urbano-Ispizua, Álvaro; González-Navarro, Europa-Azucena; Martínez-López, Joaquín; Mateos, María-Victoria; Tomas, Xavier; Setoain, Xavier; Fernández-de-Larrea, Carlos (ELSEVIER, 2025-02-11)
    Multiple myeloma (MM) remains incurable, with poor outcomes in heavily pretreated patients. Chimeric antigen receptor (CAR) T-cell therapy has emerged as a promising treatment; however, outcomes after such therapy in ...
  • AML typical mutations ( CEBPA, FLT3, NPM1) identify a high-risk chronic myelomonocytic leukemia independent of CPSS molecular 
    Castaño-Diez, Sandra; López-Guerra, Mónica; Zugasti, Inés; Calvo, Xavier; Schulz, Felicitas-Isabel; Avendano, Alejandro; Mora, Elvira; Falantes, José; Azaceta, Gemma; Ibáñez, Maríam; Chen-Liang, Tzu-Hua; Notano, Cristina; Amer, Neus; Palomo, Laura; Pomares, Helena; Vila, Jordi; Bernal-del-Castillo, Teresa; Jiménez-Vicente, Carlos; Esteban, Daniel; Guijarro, Francesca; Álamo, José; Cortés-Bullich, Albert; Torrecillas-Mayayo, Victor; Triguero, Ana; Mont-de-Torres, Lucía; Carcelero, Ester; Cardus, Aina; Germing, Ulrich; Betz, Beate; Rozman, María; Arenillas, Leónor; Zamora, Lurdes; Diez-Campelo, María; Xicoy, Blanca; Esteve, Jordi; Díaz-Bey, Marina (ELSEVIER, 2025-01-14)
    Mutations commonly associated with acute myeloid leukemia (AML), such as CEBPA, FLT3, IDH1/2, and NPM1, are rarely found in chronic myelomonocytic leukemia (CMML), and their prognostic significance in CMML has not been ...
  • Real-world data on spinal muscular atrophy in Spain: Insights from over 500 individuals in the CuidAME project 
    Puig-Ram, Cristina; Segovia, Sonia; García-Uzquiano, Rocío; Nungo-Garzón, Nancy-Carolina; Aragon-Gawinska, Karolina; García-Romero, Mar; Exposito-Escudero, Jesica-María; Carrera-García, Laura; López-Lobato, Mercedes; Paradas, Carmen; González-Mera, Laura; Molinero, Mireia-Alvarez; Gómez-Andrés, David; Toro, Esther; Fernández-Ramos, Joaquín-Alejandro; Grimalt, María-Antonia; Toledo-Bravo-de-Laguna, Laura; González-Barrios, Desire; Tizzano, Eduardo-F; Cattinari, María-Grazia; Medina, Julita; Calvo-Medina, Rocío; Munell, Francina; Sotoca, Javier; Martínez-Salcedo, Eduardo; Moreno-Escribano, Antonio; Povedano-Panades, Mónica; Fernández-García, Miguel-A; Pitarch-Castellano, Inmaculada; Vázquez-Costa, Juan-F; Natera-de-Benito, Daniel; Nascimento, Andrés (SAGE PUBLICATIONS INC, 2025-11)
    BackgroundThe new treatment paradigm in Spinal Muscular Atrophy (SMA) has introduced novel phenotypes, changes in trajectories and clinical questions not fully addressed in clinical trials. To explore these challenges, ...
  • Observational retrospective study of the treatment of Waldenström's macroglobulinemia with ibrutinib in routine clinical practice in Spain 
    Fernández-de-Larrea, Carlos; Loscertales, Javier; Cabanas-Perianes, Valentín; Freiria, Carmen; Blanchard, María-Jesús; Askari, Elham; Lorenzo-Pérez, Marcos; Abril-Parreño, Laura; López-Pardo, Jordi; Pinzón, Sergio; Díaz-Galvez, Javier; Amer, Neus; Ramírez-Payer, Ángel; García-Sánchez, Ricarda; Alcalá, María-Magdalena; Capote, Francisco-Javier; Moreno, David; Bolumburu, Celia; Rubio-Azpeitia, Eva; García-Sanz, Ramón (SAGE PUBLICATIONS LTD, 2025-07)
  • How do neurologists perceive the organization and functioning of multiple sclerosis care units? 
    Landete, Lamberto; Gómez-Ballesteros, Rocío; Meca-Lallana, Virginia; Caminero, Ana-B; Meca-Lallana, José-Eustasio; Martínez-Yelamos, Sergio; García-Domínguez, José-M; Agüera, Eduardo; García-Arcelay, Elena; Medrano, Nicolás; Villar, Luisa-M; Monreal, Enric; Maurino, Jorge (SAGE PUBLICATIONS INC, 2025-10)
    This study assessed how neurologists perceive the organization and functioning of multiple sclerosis care units. As a cross-sectional, observational study conducted in collaboration with the Spanish Society of Neurology, ...
  • Cost Analysis of the FreeStyle Libre Systems in People with Type 2 Diabetes Mellitus on Basal Insulin with Poor Glycemic Control: A Spanish Perspective 
    Ampudia-Blasco, Francisco-Javier; de-la-Cuadra-Grande, Alberto; Bellido, Virginia; Cebrián-Cuenca, Ana-María; Mezquita-Raya, Pedro; Carretero-Gómez, Juana; Hernández-Martínez, Antonio-Miguel; Oyaguez, Itziar; Gómez-Peralta, Fernando (MARY ANN LIEBERT, INC, 2026-01)
    Background and Aims: FreeStyle Libre® systems are effective and convenient glucose flash monitoring (FM) devices. This cost analysis compared FM versus self-monitoring of blood glucose (SMBG) in poorly controlled (glycated ...
  • Does Combining a Mobile Dose Calculation App with a Continuous Insulin Infusion System Improve Glycemic Control and Quality of Life Compared with a Hybrid System in Patients with Type 1 Diabetes? A Descriptive Open-Label Sequential Study 
    Pujante-Alarcón, Pedro; Álvarez, Elias-Delgado; Lambert-Goitia, Carmen; Moreira-Rodríguez, Manuela; Urbon, Lidia; Maldonado, Alfonso; García, Susana; Bau-Serrallonga, Nuria; Ruiz-Avino, Lidia; Ruiz-Palomar, Juan-M; González-López, Javier; Navarro-Hoyas, Clara-Isabel; Corcoy, Rosa; Martínez-Raimond, Teresa; Lainez-López, María; Soldevilla-Madorell, Berta; Hernández, Marta; Kyriakos, Georgios; Cotovad-Bellas, Laura; Girbes-Borras, Juan; Simo-Servant, Olga; Megía-Colet, Ana; Serrano-García, Cristina; Contreras, Cristina; Rebollo-Roman, Ángel; Diez, May; Veladesojo, Amaya; Andujar, Paula; Diez, Alberto; Abellán-Galiana, Pablo; Pla-Peris, Begoña; Fernández, Elsa; Ferrer, Marta; Gómez-Alfonso, Francisco-Javier; Menéndez-Torre, Edelmiro-Luis (MARY ANN LIEBERT, INC, 2025-10)
    Introduction: Achieving optimal glycemic control in patients with type 1 diabetes mellitus (PwT1DM) is essential to prevent complications. Continuous subcutaneous insulin infusion (CSII) systems combined with continuous ...
  • Four years on: Pregnancy and birth outcomes reported in the MSBase pregnancy, neonatal outcomes, and Women's Health Registry (2020-2024) 
    Jokubaitis, Vilija-G; Alroughani, Raed; Altintas, Ayse; Eichau, Sara; Hughes, Stella; Willekens, Barbara; Horakova, Dana; Kubala-Havrdova, Eva; Ozakbas, Serkan; Boz, Cavit; Habek, Mario; Kalincik, Tomas; Roos, Izanne; Etemadifar, Masoud; Peterka, Marek; Lechner-Scott, Jeannette; Meca-Lallana, José-Eustasio; Rous, Zuzana; Houskova, Jana; Prat, Alexandre; Girard, Marc; Ampapa, Radek; Buzzard, Katherine; Skibina, Olga; John, Nevin-A; Kermode, Allan-G; Fabis-Pedrini, Marzena-J; Foschi, Matteo; Surcinelli, Andrea; Blanco, Yolanda; Baghbanian, Seyed-Mohammad; Gerlach, Oliver; Macdonell, Richard; Pavelek, Zbysek; Stourac, Pavel; McCombe, Pamela; Laureys, Guy; Butzkueven, Helmut; van-der-Walt, Anneke; Gray, Orla (SAGE PUBLICATIONS LTD, 2025-08)
    BACKGROUND: Family planning is an important aspect of multiple sclerosis (MS), and neuromyelitis optica spectrum disorder (NMOSD) management. Knowledge gaps remain, including optimal perinatal management strategies, and ...
  • Revisiting Alma Ata: A Blueprint for Cancer Care 
    Benítez-Fuentes, Javier-David; Lastra-del-Prado, Rodrigo; Borregón-Rivilla, Miguel; de-Luna-Aguilar, Alicia; Lázaro-Sánchez, Antonio-David; Ferrandez-Arias, Asia; Rodríguez-Payá, Paula; Grau-Mirete, Beatriz; Quintanar-Verduguez, Teresa; Asensio-Martínez, Elena; Iranzo, Patricia; Callejo, Ana; Cruellas-Lapena, Mara; Gómez-Ulla, Jacobo; Rodríguez-Lescure, Álvaro (SAGE PUBLICATIONS INC, 2025-08)
    Despite significant advances in oncology, cancer care globally continues to face critical challenges, including stark disparities in access, insufficient preventive focus, fragmented primary health care (PHC) integration, ...
  • Inborn errors of immunity underlie clonal T cell expansions in large granular lymphocyte leukemia 
    Bravo-Pérez, Carlos; Gurnari, Carmelo; Huuhtanen, Jani; Kawashima, Naomi; Guarnera, Luca; Mandala, Aashray; Williams, Nakisha-D; Haddad, Christopher; Witt, Michaela; Unlu, Serhan; Brady, Zachary; Ogbue, Olisaemeka; Orland, Mark; Ahmed, Arooj; Kubota, Yasuo; Pagliuca, Simona; Durmaz, Arda; Mustjoki, Satu; Visconte, Valeria; Maciejewski, Jaroslaw-P (AMER SOC CLINICAL INVESTIGATION INC, 2025-05-01)
    BACKGROUNDT cell large granular lymphocyte leukemia (T-LGLL) is a lymphoproliferative disorder of cytotoxic T lymphocytes (CTLs), often with gain-of-function STAT3 mutations. T-LGLL represents a unique model for the study ...
  • Advancing Chrononutrition for Cardiometabolic Health: A 2023 National Heart, Lung, and Blood Institute Workshop Report 
    Dashti, Hassan-S; Jansen, Erica-C; Zuraikat, Faris-M; Dixit, Shilpy; Brown, Marishka; Laposky, Aaron; Broussard, Josiane-L; Butler, Matthew-P; Creasy, Seth-A; Crispim, Cibele-A; Depner, Christopher-M; Esser, Karyn-A; Garaulet, Marta; Hanlon, Erin-C; Makarem, Nour; Manoogian, Emily-N-C; Peterson, Courtney-M; Scheer, Frank-A-J-L; Wright-Jr, Kenneth-P; Goff, David-C; Pratt, Charlotte-A; Gamble, Karen-L; St-Onge, Marie-Pierre (WILEY, 2025-05-06)
    The circadian system maintains optimal biological functions at the appropriate time of day, and the disruption of this organization can contribute to the pathogenesis of cardiometabolic disorders. The timing of eating is ...
  • Automated Office Blood Pressure Measurements in Waiting Room or Isolated Room for Diagnosis and Phenotyping of Hypertension 
    Sánchez-Bacaicoa, Marisol; Rico, Sergio; Gullon, Alejandra; Fernández-Pardo, Jacinto; Villa, Juan; Nadiejda, Eva; Robles, Roberto; del-Aguila, José-M; Cunha, Pedro; Vassilenko, Valentina; Rodilla, Enrique; Sánchez-Muñoz-Torrero, Juan-F (WILEY, 2025-10-21)
    BACKGROUND: Automatic office blood pressure measurement (AOBPM) in the waiting room could improve the performance of diagnosing hypertension without requiring an isolated room to carry out exploration. METHODS: In a ...
  • Optimal Medical Therapy for Heart Failure and Integrated Care in Patients With Atrial Fibrillation: A Report From the ESC-EHRA EORP Atrial Fibrillation Long-Term General Registry 
    Bonini, Niccolo; Proietti, Marco; Romiti, Giulio-Francesco; Vitolo, Marco; Fawzy, Ameenathul-Mazaya; Ding, Wern-Yew; Imberti, Jacopo-Francesco; Fauchier, Laurent; Marín, Francisco; Nabauer, Michael; Dan, Gheorghe-Andrei; Potpara, Tatjana-S; Boriani, Giuseppe; Lip, Gregory-Y-H; ESC-EHRA-EORP-AF-Gen-Long-Term-Registry-Investigators (WILEY, 2025-01-07)
    BACKGROUND: Heart failure (HF) often occurs in patients with atrial fibrillation (AF), with a major impact on prognosis. Few data are available on the effect of integrated treatment strategies to improve prognosis in ...
  • Redefining the Genetic Architecture of Hypertrophic Cardiomyopathy: Role of Intermediate-Effect Variants 
    García-Hernández, Soledad; de-la-Higuera-Romero, Luis; Fernández, Adrián; Pena-Pena, María-Luisa; Mora-Ayestaran, Nerea; Basurte-Elorz, María-Teresa; Larrañaga-Moreira, José-María; Cardenas-Reyes, Ivonne; Villacorta, Eduardo; Valverde-Gómez, María; Baustista-Paves, Alicia; Veira-Villanueva, Elena; Ortiz-Genga, Martin; Lipov, Alex; Brogger, Noel; Sabater-Molina, María; Moreno-Escobar, Eduardo; Ruiz-Guerrero, Luis; Syrris, Petros; Fernández, Xusto; Piqueras-Flores, Jesús; Amor-Salamanca, Almudena; Bezzina, Connie-R; Elliott, Perry-M; Barriales-Villa, Roberto; Gimeno-Blanes, Juan-Ramón; García-Pavia, Pablo; Walsh, Roddy; Ochoa, Juan-Pablo (LIPPINCOTT WILLIAMS & WILKINS, 2025-10-14)
    BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a genetically heterogeneous disorder linked primarily to rare variants in sarcomeric genes, although recently certain nonsarcomeric genes have emerged as important contributors. ...