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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Removal of the blue component of light significantly decreases retinal damage after high intensity exposure 
    Vicente-Tejedor, Javier; Marchena, Miguel; Ramírez, Laura; García-Ayuso, Diego; Gómez-Vicente, Violeta; Sánchez-Ramos, Celia; de-la-Villa, Pedro; Germain, Francisco (PUBLIC LIBRARY SCIENCE, 2018-03-15)
    Light causes damage to the retina (phototoxicity) and decreases photoreceptor responses to light. The most harmful component of visible light is the blue wavelength (400-500 nm). Different filters have been tested, but so ...
  • Efficacy of fluoride varnishes for preventing enamel demineralization after interproximal enamel reduction. Qualitative and quantitative evaluation 
    Vicente, Ascensión; Ortiz-Ruiz, Antonio-Jose; González-Paz, Belén-Manuela; García-López, Jose; Bravo-González, Luis-Alberto (PUBLIC LIBRARY SCIENCE, 2017-04-21)
    OBJECTIVES: To evaluate quantitatively and qualitatively the changes produced to enamel after interproximal reduction and subjected to demineralization cycles, after applying a fluoride varnish (Profluorid) and a fluoride ...
  • Raltegravir plus abacavir/lamivudine in virologically suppressed HIV-1-infected patients: 48-week results of the KIRAL study 
    Troya, Jesús; Montejano, Rocío; Ryan, Pablo; Gómez, Cristina; Matarranz, Mariano; Cabello, Alfonso; Vera, Francisco; Sepúlveda, María-Antonia; Santos, Ignacio; Samperiz, Gloria; Bachiller, Pablo; Boix, Vicente; Barrufet, Pilar; Cervero, Miguel; Sanz, Jose; Solis, Javier; Yllescas, María; Valencia, Eulalia (PUBLIC LIBRARY SCIENCE, 2018-06-14)
    BACKGROUND: Long-term combination antiretroviral therapy often results in toxicity/tolerability problems, which are one of the main reasons for switching treatment. Despite the favorable profile of raltegravir (RAL), data ...
  • The association between adult attained height and sitting height with mortality in the European Prospective Investigation into Cancer and Nutrition (EPIC) 
    Sawada, Norie; Wark, Petra-A; Merritt, Melissa-A; Tsugane, Shoichiro; Ward, Heather-A; Rinaldi, Sabina; Weiderpass, Elisabete; Dartois, Laureen; His, Mathilde; Boutron-Ruault, Marie-Christine; Turzanski-Fortner, Renee; Kaaks, Rudolf; Overvad, Kim; Redondo, María-Luisa; Travier, Noemie; Molina-Portillo, Elena; Dorronsoro, Miren; Cirera-Suárez, LLuis; Ardanaz, Eva; Pérez-Cornago, Aurora; Trichopoulou, Antonia; Lagiou, Pagona; Valanou, Elissavet; Masala, Giovanna; Pala, Valeria; Peeters, Petra-H-M; van-der-Schouw, Yvonne-T; Melander, Olle; Manjer, Jonas; da-Silva, Marisa; Skeie, Guri; Tjonneland, Anne; Olsen, Anja; Gunter, Marc-J; Riboli, Elio; Cross, Amanda-J (PUBLIC LIBRARY SCIENCE, 2017-03-03)
    Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic ...
  • MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9 
    Vychytilova-Faltejskova, Petra; Merhautova, Jana; Machackova, Tana; Gutiérrez-García, Irene; García-Solano, José; Radova, Lenka; Brchnelova, Dominika; Slaba, Katerina; Svoboda, Marek; Halamkova, Jana; Demlova, Regina; Kiss, Igor; Vyzula, Rostislav; Conesa-Zamora, Pablo; Slaby, Ondrej (NATURE PUBLISHING GROUP, 2017-12)
    Growing evidence suggests that microRNAs are involved in the development and progression of colorectal cancer (CRC). In the present study, deregulation and functioning of tumor-suppressive miR-215-5p was evaluated in CRC. ...
  • Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis (vol 10, 2271, 2019) 
    Vogt, Edgar-John; Tokuhiro, Keizo; Guo, Min; Dale, Ryan; Yang, Guanghui; Shin, Seung-Wook; Jiménez-Movilla, María; Shroff, Hari; Dean, Jurrien (NATURE PUBLISHING GROUP, 2019-06-27)
    An amendment to this paper has been published and can be accessed via a link at the top of the paper.
  • Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis 
    Vogt, Edgar-John; Tokuhiro, Keizo; Guo, Min; Dale, Ryan; Yang, Guanghui; Jiménez-Movilla, María; Shroff, Hari; Dean, Jurrien (NATURE PUBLISHING GROUP, 2019-05-22)
    Following fertilization, cortical granules exocytose ovastacin, a metalloendopeptidase that cleaves ZP2 in the zona pellucida surrounding mouse eggs to prevent additional sperm binding. Using high- and super-resolution ...
  • CD300a inhibits CD16-mediated NK cell effector functions in HIV-1-infected patients 
    Vitalle, Joana; Terren, Íñigo; Orrantia, Ane; Pérez-Garay, Raquel; Vidal, Francesc; Iribarren, Jose-A; Rodríguez, Carmen; López-Lirola, Ana-María; Bernal-Morell, Enrique; Zenarruzabeitia, Olatz; Borrego, Francisco (NATURE PUBLISHING GROUP, 2019-12)
  • The ARID1B spectrum in 143 patients: from nonsyndromic intellectual disability to Coffin-Siris syndrome (vol 21, pg 1295, 2019) 
    van-der-Sluijs, Pleuntje-J; Jansen, Sandra; Vergano, Samantha-A; Adachi-Fukuda, Miho; Alanay, Yasemin; AlKindy, Adila; Baban, Anwar; Bayat, Allan; Beck-Woedl, Stefanie; Berry, Katherine; Bijlsma, Emilia-K; Bok, Levinus-A; Brouwer, Alwin-F-J; van-der-Burgt, Ineke; Campeau, Philippe-M; Canham, Natalie; Chrzanowska, Krystyna; Chu, Yoyo-W-Y; Chung, Brain-H-Y; Dahan, Karin; De-Rademaeker, Marjan; Destree, Anne; Dudding-Byth, Tracy; Earl, Rachel; Elcioglu, Nursel; Elias, Ellen-R; Fagerberg, Christina; Gardham, Alice; Gener, Blanca; Gerkes, Erica-H; Grasshoff, Ute; van-Haeringen, Arie; Heitink, Karin-R; Herkert, Johanna-C; den-Hollander, Nicolette-S; Horn, Denise; Hunt, David; Kant, Sarina-G; Kato, Mitsuhiro; Kayserili, Hulya; Kersseboom, Rogier; Kilic, Esra; Krajewska-Walasek, Malgorzata; Lammers, Kylin; Laulund, Lone-W; Lederer, Damien; Lees, Melissa; López-González, Vanesa; Maas, Saskia; Mancini, Grazia-M-S; Marcelis, Carlo; Martínez, Francisco; Maystadt, Isabelle; McGuire, Marianne; Mckee, Shane; Mehta, Sarju; Metcalfe, Kay; Milunsky, Jeff; Mizuno, Seiji; Moeschler, John-B; Netzer, Christian; Ockeloen, Charlotte-W; Oehl-Jaschkowitz, Barbara; Okamoto, Nobuhiko; Olminkhof, Sharon-N-M; Orellana, Carmen; Pasquier, Laurent; Pottinger, Caroline; Riehmer, Vera; Robertson, Stephen-P; Roifman, Maian; Rooryck, Caroline; Ropers, Fabienne-G; Rosello, Mónica; Ruivenkamp, Claudia-A-L; Sagiroglu, Mahmut-S; Sallevelt, Suzanne-C-E-H; Sanchís-Calvo, Amparo; Simsek-Kiper, Pelin-O; Soares, Gabriela; Solaeche, Lucía; Sonmez, Fatma-Mujgan; Splitt, Miranda; Steenbeek, Duco; Stegmann, Alexander-P-A; Stumpel, Constance-T-R-M; Tanabe, Saori; Uctepe, Eyyup; Utine, G-Eda; Veenstra-Knol, Hermine-E; Venkateswaran, Sunita; Vilain, Catheline; Vincent-Delorme, Catherine; Vulto-van-Silfhout, Anneke-T; Wheeler, Patricia; Wilson, Golder-N; Wilson, Louise-C; Wollnik, Bernd; Kosho, Tomoki; Wieczorek, Dagmar; Eichler, Evan; Pfundt, Rolph; de-Vries, Bert-B-A; Clayton-Smith, Jill; Santen, Gijs-W-E (NATURE PUBLISHING GROUP, 2019-09)
    The original version of this Article contained an error in the spelling of the author Pleuntje J. van der Sluijs, which was incorrectly given as Eline (P. J.) van der Sluijs. This has now been corrected in both the PDF and ...
  • Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice 
    Shin, Seung-Wook; Vogt, Edgar-John; Jiménez-Movilla, María; Baibakov, Boris; Dean, Jurrien (NATURE PUBLISHING GROUP, 2017-11-21)
    Degradation of maternal proteins by the ubiquitin-proteasome system (UPS) accompanies the maternal-to-zygotic transition. DPPA3/Stella/PGC7, encoded by a maternal effect gene, is present in the nucleus and cytoplasm of ...
  • Plasma lipid profiles discriminate bacterial from viral infection in febrile children 
    Wang, Xinzhu; Nijman, Ruud; Camuzeaux, Stephane; Sands, Caroline; Jackson, Heather; Kaforou, Myrsini; Emonts, Marieke; Herberg, Jethro-A; Maconochie, Ian; Carrol, Enitan-D; Paulus, Stephane-C; Zenz, Werner; Van-der-Flier, Michiel; de-Groot, Ronald; Martinon-Torres, Federico; Schlapbach, Luregn-J; Pollard, Andrew-J; Fink, Colin; Kuijpers, Taco-T; Anderson, Suzanne; Lewis, Matthew-R; Levin, Michael; McClure, Myra; Gormley, Stuart; Hamilton, Shea; Hourmat, Bernardo; Hoggart, Clive; Sancho-Shimizu, Vanessa; Wright, Victoria; Abdulla, Amina; Agapow, Paul; Bartlett, Maeve; Bellos, Evangelos; Eleftherohorinou, Hariklia; Galassini, Rachel; Inwald, David; Mashbat, Meg; Menikou, Stefanie; Mustafa, Sobia; Nadel, Simon; Rahman, Rahmeen; Thakker, Clare; Coin, Lachlan-M-J; Bokhand, S; Power, Sue; Barham, Heather; Pathan, N; Ridout, Jenna; White, Deborah; Thurston, Sarah; Faust, S; Patel, S; McCorkell, Jenni; Davies, P; Crate, Lindsey; Navarra, Helen; Carter, Stephanie; Ramaiah, R; Patel, Rekha; Tuffrey, Catherine; Gribbin, Andrew; McCready, Sharon; Peters, Mark; Hardy, Katie; Standing, Fran; O'Neill, Lauren; Abelake, Eugenia; Deep, Akash; Nsirim, Eniola; Willis, Louise; Young, Zoe; Royad, C; White, Sonia; Fortune, P-M; Hudnott, Phil; Alvez-González, Fernando; Barral-Arca, Ruth; Cebey-López, Miriam; Curras-Tuala, María-José; García, Natalia; García-Vicente, Luisa; Gómez-Carballa, Alberto; Gómez-Rial, Jose; Grela-Beiroa, Andrea; Justicia-Grande, Antonio; Leborans-Iglesias, Pilar; Martínez-Santos, Alba-Elena; Martinon-Torres, Federico; MartinonTorres, Nazareth; Martinon-Sánchez, Jose-María; Morillo-Gutiérrez, Beatriz; Mosquera-Pérez, Belén; Obando-Pacheco, Pablo; Pardo-Seco, Jacobo; Pischedda, Sara; RiveroCalle, Irene; Rodríguez-Tenreiro, Carmen; Redondo-Collazo, Lorenzo; Salas-Ellacuriagal, Antonio; Seren-Fernández, Sonia; Porto-Silva, María-del-Sol; Vega, Ana; Vilanova-Trillo, Lucía; Salas, Antonio; Reyes, Susana-Beatriz; León-León, María-Cruz; Navarro-Mingorance, Álvaro; Gabaldo-Barrios, Xavier; Onate-Vergara, Eider; Concha-Torre, Andrés; Vivanco, Ana; Fernández, Reyes; Giménez-Sánchez, Francisco; Sánchez-Forte, Miguel; Rojo, Pablo; Ruiz-Contreras, J; Palacios, Alba; Epalza-Ibarrondo, Cristina; Fernández-Cooke, Elizabeth; Navarro, Marisa; Álvarez-Álvarez, Cristina; Lozano, María-José; Carreras, Eduardo; Brio-Sanagustin, Sonia; Neth, Olaf; Martínez-Padilla, María-del-Carmen; Prieto-Tato, Luis-Manuel; Guillen, Sara; Fernández-Silveira, Laura; Moreno, David; van-Furth, A-M-Tutu; Boeddha, N-P; Driessen, G-J-A; Emonts, M; Hazelzet, J-A; Pajkrt, D; Sanders, E-A-M; van-de-Beek, D; van-der-Ende, A; Philipsen, H-L-A; Adeel, A-O-A; Breukels, M-A; Brinkman, D-M-C; de-Korte, C-C-M-M; de-Vries, E; de-Waal, W-J; Dekkers, R; Dings-Lammertink, A; Doedens, R-A; Donker, A-E; Dousma, M; Faber, T-E; Gerrits, G-P-J-M; Gerver, J-A-M; Heidema, J; Homan-van-der-Veen, J; Jacobs, M-A-M; Jansen, N-J-G; Kawczynski, P; Klucovska, K; Kneyber, M-C-J; Koopman-Keemink, Y; Langenhorst, V-J; Leusink, J; Loza, B-F; Merth, I-T; Miedema, C-J; Neeleman, C; Noordzij, J-G; Obihara, C-C; van-Overbeek-van-Gils, A-L-T; Poortman, G-H; Potgieter, S-T; Potjewijd, J; Rosias, P-P-R; Sprong, T; ten-Tussher, G-W; Thio, B-J; Tramper-Stranders, G-A; van-Deuren, M; van-der-Meer, H; van-Kuppevelt, A-J-M; van-Wermeskerken, A-M; Verwijs, W-A; Wolfs, T-F-W; Agyeman, Philipp; Aebi, Christoph; Berger, Christoph; Agyeman, Philipp; Aebi, Christoph; Giannoni, Eric; Stocker, Martin; Posfay-Barbe, Klara-M; Heininger, Ulrich; Bernhard-Stirnemann, Sara; Niederer-Loher, Anita; Kahlert, Christian; Hasters, Paul; Relly, Christa; Baer, Walter; Berger, Christoph; Frederick, Hannah; Jennings, Rebecca; Johnston, Joanne; Kenwright, Rhian; Pinnock, Elli; Agbeko, Rachel; Secka, Fatou; Bojang, Kalifa; Sarr, Isatou; Kebbeh, Ngange; Sey, Gibbi; Momodou, Saidy-Khan; Cole, Fatoumata; Thomas, Gilleh; Antonio, Martin; Klobassa, Daniela-S; Binder, Alexander; Schweintzger, Nina-A; Sagmeister, Manfred; Baumgart, Hinrich; Baumgartner, Markus; Behrends, Uta; Biebl, Ariane; Birnbacher, Robert; Blanke, Jan-Gerd; Boelke, Carsten; Breuling, Kai; Brunner, Juergen; Buller, María; Dahlem, Peter; Dietrich, Beate; Eber, Ernst; Elias, Johannes; Emhofer, Josef; Etschmaier, Rosa; Farr, Sebastian; Girtler, Ylenia; Grigorow, Irina; Heimann, Konrad; Ihm, Ulrike; Jaros, Zdenek; Kalhoff, Hermann; Kaulfersch, Wilhelm; Kemen, Christoph; Klocker, Nina; Koester, Bernhard; Kohlmaier, Benno; Komini, Eleni; Kramer, Lydia; Neubert, Antje; Ortner, Daniel; Pescollderungg, Lydia; Pfurtscheller, Klaus; Reiter, Karl; Ristic, Goran; Roedl, Siegfried; Sellner, Andrea; Sonnleitner, Astrid; Sperl, Matthias; Stelzl, Wolfgang; Till, Holger; Trobisch, Andreas; Vierzig, Anne; Vogel, Ulrich; Weingarten, Christina; Welke, Stefanie; Wimmer, Andreas; Wintergerst, Uwe; Wueller, Daniel; Zaunschirm, Andrew; Ziuraite, Ieva; Zukovskaja, Veslava (NATURE PORTFOLIO, 2019-11-27)
    Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection are often non-specific, and there is no definitive test for the accurate diagnosis ...
  • Enamel Resistance to Demineralization After Bracket Debonding Using Fluoride Varnish 
    Vicente, Ascensión; Ortiz-Ruiz, Antonio-Jose; García-López, Miriam; Martínez-Beneyto, Yolanda; Bravo-González, Luis-Alberto (NATURE PORTFOLIO, 2017-11-09)
    The aim of this study was to evaluate the elemental content and morphology of enamel subjected to demineralization cycles after bracket debonding, adhesive remnant removal, and application of a fluoride varnish. 125 bovine ...
  • Modifiable lifestyle behaviors, but not a genetic risk score, associate with metabolic syndrome in evening chronotypes 
    Vera, Beatriz; Dashti, Hassan-S; Gómez-Abellán, Purificación; Hernández-Martínez, Antonio-Miguel; Esteban, Alberto; Scheer, Frank-A-J-L; Saxena, Richa; Garaulet, Marta (NATURE PORTFOLIO, 2018-01-17)
    Evening chronotype associates with health complications possibly via lifestyle factors, while the contribution of genetics is unknown. The aim was to study the relative contributions of genetics, lifestyle, and circadian-related ...
  • Climate drivers of the 2017 devastating fires in Portugal 
    Turco, Marco; Jerez, Sonia; Augusto, Sofia; Tarin-Carrasco, Patricia; Ratola, Nuno; Jiménez-Guerrero, Pedro; Trigo, Ricardo-M (NATURE PORTFOLIO, 2019-10-10)
    A record 500,000 hectares burned in Portugal during the extreme wildfire season of 2017, with more than 120 human lives lost. Here we analyse the climatic factors responsible for the burned area (BA) from June to October ...
  • Cone degeneration is triggered by the absence of USH1 proteins but prevented by antioxidant treatments 
    Trouillet, Alix; Dubus, Elisabeth; Degardin, Julie; Estivalet, Amrit; Ivkovic, Ivana; Godefroy, David; García-Ayuso, Diego; Simonutti, Manuel; Sahly, Iman; Sahel, Jose-A; El-Amraoui, Aziz; Petit, Christine; Picaud, Serge (NATURE PORTFOLIO, 2018-01-31)
    Usher syndrome type 1 (USH1) is a major cause of inherited deafness and blindness in humans. The eye disorder is often referred to as retinitis pigmentosa, which is characterized by a secondary cone degeneration following ...
  • Differential miRNA expression profile and proteome in plasma exosomes from patients with paroxysmal nocturnal hemoglobinuria 
    Teruel-Montoya, Raúl; Luengo-Gil, Ginés; Vallejo, Fernando; Enrique-Yuste, Jose; Bohdan, Natalia; García-Barbera, Nuria; Espín, Salvador; Martínez, Constantino; Espín, Juan-Carlos; Vicente, Vicente; Martínez-Martínez, Irene (NATURE PORTFOLIO, 2019-03-05)
    Paroxysmal Nocturnal Hemoglobinuria (PNH) is a clonal disease of blood cells caused by the lack of glycosyl phosphatidyl inositol anchored proteins bound to the cell membrane. In consequence, erythrocytes lead to intravascular ...
  • Improving porcine in vitro fertilization output by simulating the oviductal environment 
    Soriano-Úbeda, Cristina; García-Vázquez, Francisco-Alberto; Romero-Aguirregomezcorta, Jon; Matas-Parra, Carmen (NATURE PORTFOLIO, 2017-03-06)
  • A Multi-Locus Genetic Risk Score for Primary Open-Angle Glaucoma (POAG) Variants Is Associated with POAG Risk in a Mediterranean Population: Inverse Correlations with Plasma Vitamin C and E Concentrations 
    Zanon-Moreno, Vicente; Ortega-Azorín, Carolina; Asensio-Marquez, Eva-M; García-Medina, José-Javier; Pinazo-Duran, María-D; Coltell, Oscar; Ordovas, Jose-M; Corella, Dolores (MDPI AG, 2017-11)
    Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. The genetics of POAG are complex, and population-specific effects have been reported. Although many polymorphisms associated with POAG risk have ...
  • Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma 
    Molina, María-L; García-Bernal, David; Martínez, Salvador; Valdor, Rut (MDPI, 2020-01)
    Glioblastoma (GB) has been shown to up-regulate autophagy with anti- or pro-oncogenic effects. Recently, our group has shown how GB cells aberrantly up-regulate chaperone-mediated autophagy (CMA) in pericytes of peritumoral ...
  • Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease 
    Sánchez-Campillo, María; Ruiz-Pastor, María-José; Gázquez, Antonio; Marín-Muñoz, Juan-Carlos; Noguera-Perea, María-Fuensanta; Ruiz-Alcaraz, Antonio-J; Manzanares-Sánchez, Salvadora; Antúnez-Almagro, Carmen; Larqué, Elvira (MDPI, 2020-01-01)
    The protein Major Facilitator Superfamily Domain containing 2A (MFSD2a) was recently described as the primary carrier for docosahexaenoic acid (DHA) into the brain. Alzheimer's disease (AD) is a progressive neurodegenerative ...