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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk 
    Marín-Quílez, Ana; Sánchez-Fuentes, Ana; Zamora-Cánovas, Ana; Gómez-González, Pedro-Luis; Díaz-Ajenjo, Lorena; Benito, Rocío; Rodríguez-Alen, Agustin; Sevivas, Teresa; Murciano, Thais; Murillo, Laura; Butta, Nora-V; Revilla, Nuria; Campos, Rosa; Escribano, Paola; Esteve, Jordi; Fernández-Mosteirin, Nuria; Ferrer-Marín, Francisca; Hernández, Laura; Huerta-Aragones, Jorge; León, Antonio; López-Duarte, Mónica; López, Eugenia; Martín-Salces, Mónica; Nomdedeu, Meritxell; Ona, Raquel; Peláez-Pleguezuelos, Irene; Ramos, Fernando; Sebastián, Elena; Serrano-Jara, Claudia; Sierra-Aisa, Cristina; Vidal-Laso, Rosa; González-Porras, José-Ramón; Lozano-Almela, María-Luisa; Bastida, José-María; Rivera, José (WILEY, 2025-10)
    Inherited thrombocytopenia (IT) with germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk (10%-45%) of developing haematological malignancy (IT-HM). We evaluated the clinical, platelet and molecular characteristics ...
  • Anti-thymocyte globulin in immune-mediated cytopenias: A monocentric experience and literature review 
    Guarnera, Luca; Ahmed, Arooj; Bravo-Pérez, Carlos; Ogbue, Olisaemeka-D; D'Addona, Matteo; Brady, Zachary; Unlu, Serhan; Haddad, Christopher; Mandala, Aashray; Durmaz, Arda; Gurnari, Carmelo; Visconte, Valeria; Maciejewski, Jaroslaw-P (WILEY, 2025-07)
    Anti-thymocyte globulin in multi-refractory immune-mediated cytopenia is an effective treatment, with response rate as high as 65%. Younger patients, presenting with thrombocytopenia or neutropenia, and those with LGL and ...
  • Comprehensive analysis of relapsed-refractory mature B-cell non-Hodgkin lymphoma in children and adolescents 
    Mato, Sara; Carita, Lorenzo; Colmenero, Ariadna; Andrés, Mara; Balague, Olga; Andion, Maitane; Astigarraga, Itziar; Celis, Veronica; Mendoza, Carmen; Guerra-García, Pilar; Valero, Lorena; Galera-Miñarro, Ana-María; Tallon, María; Pol, Melina; Castrejon-de-Anta, Natalia; Frauenfeld, Leónie; García, Noelia; Campo, Elias; Salaverria, Itziar; Verdu-Amoros, Jaime (WILEY, 2025-05)
    The outcome of B-cell non-Hodgkin lymphoma (B-NHL) in children and adolescents has improved significantly over recent decades due to risk-adapted strategies and the use of immunotherapy. However, refractory or relapsed ...
  • Placental growth factor before 11 weeks for screening of preterm preeclampsia: The PreMoM study 
    López-Marmol, Rocío; Ávila-Cabreja, José-Alejandro; de-Haro-Romero, Teresa; de-Paco-Matallana, Catalina; Ocon-Hernández, Olga; González-Vanegas, Otilia; Carretero-Lucena, Pilar; Carrillo, María-Paz; Delgado-Marín, Juan-Luis; Rolle, Valeria; Gormus, Uzay; Oraha, Liza; Gil, María-M; Molina, Francisca-S (WILEY, 2025-10)
    INTRODUCTION: Our objective was to compare the predictive performance of the Fetal Medicine Foundation (FMF) competing-risk model for preterm preeclampsia (PE) screening using placental growth factor (PlGF) measurements ...
  • Pig Seminal Plasma Extracellular Vesicles Enhance Motility During Preservation of Epididymal Spermatozoa but Impair Capacitation and IVF Parameters 
    Moya-Fernández, Ana; Toledo-Guardiola, Santa-María; Silke, Peter; Navarro-Serna, Sergio; Matas-Parra, Carmen (WILEY, 2025-12)
    BACKGROUND: Extracellular vesicles (EVs) produced by accessory sex glands play a key role in sperm functionality, influencing motility, viability, acrosome integrity, metabolic activity, and capacitation. Most studies on ...
  • The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation 
    Martínez-Hernández, Jesús; Garriga, Ferran; Ahmad, Adeel; Padilla, Lorena; Maside, Carolina; Bonet, Sergi; Barranco-Boada, María-Isabel; Roca, Jordi; Pastor, Luis-Miguel; Yeste, Marc (WILEY, 2026-03)
    BACKGROUND: The oxytocin receptor (OR) is a G-protein-coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. OBJECTIVES: In this study, using the pig as a model, ...
  • Failure rate of the pulmonary embolism rule-out criteria rule for adults 35 years or younger: Findings from the RIETE Registry 
    Jossein, Thibaut; Mazzolai, Lucía; Lorenzo-Hernández, Alicia; Otalora-Valderrama, Sonia; Zdraveska, Marija; Rivas-Guerrero, Agustina; López-Ruiz, Antonio; Di-Micco, Pierpaolo; Monreal, Manuel; Hugli, Olivier (WILEY, 2025-04)
    BACKGROUND: The use of a computed tomography pulmonary angiogram to diagnose pulmonary embolism (PE) has increased, leading not only to higher PE diagnoses but also to overdiagnosis and unnecessary radiation exposure, even ...
  • Development of a Short Telomere Zebrafish Model for Accelerated Aging Research and Antiaging Drug Screening 
    Hernández-Silva, David; López-Abellán, María-Dolores; Martínez-Navarro, Francisco-J; García-Castillo, Jesús; Cayuela-Fuentes, María-Luisa; Alcaraz-Pérez, Francisca (WILEY, 2025-06)
    Increased life expectancy is associated with a higher risk of age-related diseases, which represent a major public health challenge. Animal models play a crucial role in aging research, enabling the study of diseases at ...
  • Clinical Practice Guidelines on Normal Labour and Childbirth: A Systematic Review 
    Hernández-Martínez, María-Loreto; Molina-Rodríguez, Alonso; Maes-Carballo, Marta; Bueno-Cavanillas, Aurora; Cano-Ibáñez, Naomi; Amezcua-Prieto, Carmen (WILEY, 2025-09-23)
    BACKGROUND: Clinical Practice Guidelines (CPGs) are essential for promoting evidence-based maternal and neonatal care, but inconsistencies in recommendations can be confusing. OBJECTIVES: To analyse the quality and reporting ...
  • Aspirin, Birthweight, and Large-For-Gestational-Age Neonates: A Secondary Analysis of the ASPRE Trial 
    Rolnik, Daniel-L; Poon, Liona-C; Syngelaki, Argyro; Wright, David; O'Gorman, Neil; de-Paco-Matallana, Catalina; Akolekar, Ranjit; Janga, Deepa; Singh, Mandeep; Molina, Francisca-S; Persico, Nicola; Jani, Jacques-C; Plasencia, Walter; Papaioannou, George; Tenenbaum-Gavish, Kinneret; Meiri, Hamutal; Nicolaides, Kypros-H (WILEY, 2025-10)
    OBJECTIVE: To investigate the effects of aspirin on the distribution of birthweight and its impact on the rates of large-for-gestational-age (LGA) neonates. DESIGN: Secondary analysis of the Combined Multimarker Screening ...
  • Discovering Genetic Variants in Hypertrophic Cardiomyopathy With Multiple Machine Learning Techniques 
    Lozano-Paredes, Dafne; Bote-Curiel, Luis; Sabater-Molina, María; Bielza, Concha; Gimeno-Blanes, Juan-Ramón; Muñoz-Romero, Sergio; Gimeno-Blanes, F-Javier; Larrañaga, Pedro; Rojo-Álvarez, José-Luis (IEEE COMPUTER SOC, 2025-07)
    Hypertrophic cardiomyopathy is known to have strong genetic foundations. However, only some studies have addressed the complex network of co-expressed genes and variants that modify the phenotype. Machine learning methods ...
  • Segmentation Techniques Applied to CNNs for Cervical Cancer Classification 
    Ortiz-González, Ana; Martínez-Espana, Raquel; Morales-García, Juan; Imbernon, Baldomero; Martínez-Mas, José; Álvarez, Mauricio-A; Romero, Óscar-David; Martínez-Cendán, Juan-Pedro; Bueno-Crespo, Andrés (IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2025)
  • CAPI-Detect: machine learning in capillaroscopy reveals new variables influencing diagnosis 
    Lledo-Ibáñez, Gema-M; Comet, Luis-Saez; Dapena, Mayka-Freire; Mesa-Navas, Miguel; Martín-Cascón, Miguel; Guillén-del-Castillo, Alfredo; Simeon, Carmen-Pilar; Martínez-Robles, Elena; Todoli-Parra, José; Varela, Diana-Cristina; Maldonado, Genesis; Marín, Adela; Pérez-Abad, Laura; Aramburu, Jimena; Vela, Laura; Ramos-Ibáñez, Eduardo; Gracia-Tello, Borja-del-Carmelo (OXFORD UNIV PRESS, 2025-06-01)
    OBJECTIVES: Nailfold videocapillaroscopy (NVC) is the gold standard for diagnosing SSc and differentiating primary from secondary RP. The CAPI-Score algorithm, designed for simplicity, classifies capillaroscopy scleroderma ...
  • Thorough assessment of the effectiveness of belimumab in a large Spanish multicenter cohort of systemic lupus erythematosus patients 
    Altabas-González, Irene; Pego-Reigosa, José-María; Mourino, Coral; Jiménez, Norman; Hernández-Martin, Andrea; Casafont-Sole, Ivette; Font-Urguelles, Judit; Roman-Ivorra, José-Andrés; de-la-Rubia-Navarro, Marta; Galindo-Izquierdo, María; Salman-Monte, Tarek-Carlos; Narváez, Javier; Vidal-Montal, Paola; García-Villanueva, María-Jesús; Garrote-Corral, Sandra; Blázquez-Canamero, María-Ángeles; Marras-Fernández-Cid, Carlos; Piqueras-García, María-Mercedes; Martínez-Barrio, Julia; Sánchez-Lucas, Marina; Cortés-Hernández, Josefina; Penzo, ELeónora; Calvo-Alen, Jaime; de-Dios, Juan-Ramón; Álvarez-Rodríguez, Belén; Vasques-Rocha, Margarida; Tomero, Eva; Menor-Almagro, Raúl; Gandia, Myriam; Gómez-Puerta, José-A; Frade-Sosa, Beatriz; Ramos-Giraldez, Consuelo; Trapero-Pérez, Carmen; Diez, Elvira; Moriano, Clara; Muñoz-Jiménez, Alejandro; Rua-Figueroa, Íñigo-Jesús (OXFORD UNIV PRESS, 2025-01-01)
    OBJECTIVES: To provide an overview on the current use of belimumab (BLM) in SLE patients in clinical practice and to examine its efficacy in terms of standardized outcomes, drug survival, as well as patient and safety ...
  • Evaluation of the effectiveness and safety of avapritinib in real-world Spanish cases with gastrointestinal stromal tumor and D842V-PDGFRA mutation 
    Núñez-Hernández, Isaac; Gómez-Palmero, Cristina; Delgado, Juan-Ramón; Nuno, Ana; Sala-González, María-Ángeles; Ageitos, Ana-Gonzalez; Aguilar, Héctor; Ayala-de-Miguel, Pablo; Condori, Elizabeth; Díaz-Beveridge, Roberto; Martínez-García, Jerónimo; Marquina, Gloria; Varela-Pose, Vanesa; Veas-Rodríguez, Joel; Serrano, César (OXFORD UNIV PRESS, 2025-05-08)
    INTRODUCTION: Gastrointestinal stromal tumors (GISTs) are the most common sarcoma subtype. Patients with unresectable or metastatic GISTs harboring the D842V mutation in the PDGFRA gene have a poor prognosis due to intrinsic ...
  • Nutritional status and quality of life of patients with advanced gastroenteropancreatic neuroendocrine neoplasms in Spain: the NUTRIGETNE (GETNE-S2109) study 
    del-Olmo-García, Maribel; Hernández-Rienda, Lorena; García-Carbonero, Rocío; Hernando, Jorge; Custodio, Ana; Antón-Pascual, Beatriz; Gómez, Marta; Milla, Samara-Palma; Suarez, Lorena; Bellver, Marta; Alonso, Vicente; Serrano, Raquel; Valdés, Nuria; Melian, Marcos; Febrero, Beatriz; Sampedro-Núñez, Miguel-Antonio; Biarnes, Josefina; Díaz-Pérez, José-Ángel; Molina-Cerrillo, Javier; López, Carlos; Martínez-Olmos, Miguel-Ángel; Merino-Torres, Juan-Francisco; Capdevila, Jaume; Pla, María-Argente; NUTRIGETNE-Group, Paula (OXFORD UNIV PRESS, 2025-02-06)
    Patients with advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) have impaired nutritional and physical performance due to the cancer pathophysiology and its treatment. The NUTRIGETNE study sought to ...
  • Characterization of thrombosis risk in ambulatory patients with cancer: results of the observational, prospective, multicenter CARTAGO study 
    Trujillo-Santos, Javier; García-Escobar, Ignacio; Salgado, Mercedes; Araujo, Antonio; Martínez-de-Castro, Eva; Molina, Raquel; Castellón-Rubio, Victoria-Eugenia; Domenech, Pere; Gallardo, Enrique; Colome, Esteve; Torres, Ferran; Benítez-Montanez, José-Carlos; Porta, Rut; Lobo-de-Mena, Miriam; Malheiro, Mariana; Font, Carme; Brozos-Vázquez, Elena; Garicano, Fernando; Sapena, Victor; Costa, Ana-Lucía; Albuquerque, Ana-Cristina; Cerezuela-Fuentes, Pablo; CARTAGO-Study-Grp, Sara (OXFORD UNIV PRESS, 2025-08-04)
    BACKGROUND: Venous thromboembolism (VTE) is one of the leading causes of death in patients with cancer. Currently, there is a need to develop an easily applicable risk model that can identify patients who will benefit from ...
  • Three-year survival follow-up of patients with gastrointestinal cancer treated during the COVID-19 pandemic in Spain: data from the PANDORA-TTD20 study 
    García-Alfonso, Pilar; Jiménez-Fonseca, Paula; Soto-Alsar, Javier; Baraibar, Iosune; Santos, Cristina; La-Casta, Adelaida; Ghanem, Ismael; Pulido-Cortijo, Gema; Marino-Mendez, Axel; Pazo-Cid, Roberto; Vera, Ruth; Melian, Marcos; Alcaide, Julia; Grana, Begoña; Paez, David; Gallego, Inmaculada; Lobo-de-Mena, Miriam; Borregón-Rivilla, Miguel; Fernández-Montes, Ana; Martínez-de-Castro, Eva; Carmona-Bayonas, Alberto; Aranda, Enrique (OXFORD UNIV PRESS, 2025-08-04)
    INTRODUCTION: The initial SARS-CoV-2 pandemic wave in Spain in 2020 precipitated significant paradigm shifts in gastrointestinal oncology patient management. This study captures the "Zeitgeist" of this period by analyzing ...
  • Kidney replacement therapy for men and women according to the ERA Registry and the USRDS 
    Stel, Vianda-S; Chesnaye, Nicholas-C; Boenink, Rianne; Boerstra, Brittany-A; Astley, Megan-E; Methven, Shona; Heylen, Line; Resic, Halima; Ten-Dam, Marc-A-G-J; Hommel, Kristine; Solbu, Marit-D; Slon-Roblero, María-F; Areste-Fosalba, Nuria; Radunovic, Danilo; García-López, Héctor; Buchwinkler, Lukas; Guidotti, Rebecca; Lassalle, Mathilde; Santiuste-de-Pablos, Carmen; Stendahl, María; Indridason, Olafur-S; Escriba, Almudena; Bouzas-Caamano, María-Encarnación; Rodríguez-Arévalo, Olga-Lucía; Moustakas, George; Hernández-Vargas, Hermann; Ortiz, Alberto; Kramer, Anneke (OXFORD UNIV PRESS, 2025-10-31)
    BACKGROUND: This paper compares the incidence and prevalence of kidney replacement therapy (KRT), kidney transplantation rates, and mortality on KRT between Europe and the United States (US), including sex comparisons. ...
  • Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study 
    Ortiz, Alberto; Kramer, Anneke; Ariceta, Gema; Rodríguez-Arévalo, Olga-Lucía; Gjerstad, Ann-C; Santiuste-de-Pablos, Carmen; Trujillo-Alemán, Sara; Ferraro, Pietro-Manuel; Methven, Shona; Santamaria, Rafael; Naumovic, Radomir; Resic, Halima; Hommel, Kristine; Segelmark, Marten; Ambuehl, Patrice-M; Sorensen, Soren-S; Parmentier, Cyrielle; Vidal, Enrico; Bakkaloglu, Sevcan-A; Plumb, Lucy; Palsson, Runolfur; Kerschbaum, Julia; ten-Dam, Marc-A-G-J; Stel, Vianda-S; Jager, Kitty-J; Torra, Roser (OXFORD UNIV PRESS, 2025-04-28)
    BACKGROUND: Inherited kidney diseases (IKDs) and congenital anomalies of the kidney and urinary tract (CAKUT) are causes of kidney failure requiring kidney replacement therapy (KRT) that major renal registries usually ...