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Envíos recientes

02.01.01. Investigación y comunicación científica: Envíos recientes

  • Improvement of the Flavanol Profile and the Antioxidant Capacity of Chocolate Using a Phenolic Rich Cocoa Powder 
    González-Barrio, Rocío; Nunez-Gómez, Vanesa; Cienfuegos-Jovellanos, Elena; García-Alonso, Francisco-Javier; Periago-Caston, Ma-Jesús (MDPI, 2020-02)
    Chocolate is made from cocoa, which is rich in (poly)phenols that have a high antioxidant capacity and are associated with the prevention of chronic diseases. In this study, a new production process was evaluated in order ...
  • Novel CYP4F22 mutations associated with autosomal recessive congenital ichthyosis (ARCI). Study of the CYP4F22 c.1303C>T founder mutation 
    Esperon-Moldes, Uxia; Ginarte-Val, Manuel; Rodríguez-Pazos, Laura; Fachal, Laura; Martín-Santiago, Ana; Vicente, Asuncion; Jiménez-Gallo, David; Guillén-Navarro, Encarna; Martorell-Sampol, Loreto; González-Ensenat, María-Antonia; Vega, Ana (PUBLIC LIBRARY SCIENCE, 2020-02-18)
    Mutations in CYP4F22 cause autosomal recessive congenital ichthyosis (ARCI). However, less than 10% of all ARCI patients carry a mutation in CYP4F22. In order to identify the molecular basis of ARCI among our patients (a ...
  • Neprilysin inhibition, endorphin dynamics, and early symptomatic improvement in heart failure: a pilot study 
    Revuelta-López, Elena; Nunez, Julio; Gastelurrutia, Paloma; Cediel, German; Januzzi, James-L; Ibrahim, Nasrien-E; Emdin, Michele; VanKimmenade, Roland; Pascual-Figal, Domingo-Andrés; Nunez, Eduardo; Gommans, Frank; Lupon, Josép; Bayes-Genis, Antoni (WILEY PERIODICALS, INC, 2020-04)
    AIM: Sacubitril/valsartan is a first-in-class angiotensin receptor-neprilysin inhibitor developed for the treatment of heart failure with reduced ejection fraction. Its benefits are achieved through the inhibition of ...
  • Melatonin as an Agent for Direct Pulp-Capping Treatment 
    Guerrero-Gironés, Julia; Alcaina-Lorente, Antonia; Ortiz-Ruiz, Clara; Ortiz-Ruiz, Eduardo; Pecci-Lloret, María-P; Rodríguez-Lozano, Francisco-Javier; Martínez, Carlos-M; Ortiz-Ruiz, Antonio-José (MDPI, 2020)
    Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts. This research aimed to evaluate the pulp response to melatonin ...
  • A Critical Mutualism - Competition Interplay Underlies the Loss of Microbial Diversity in Sedentary Lifestyle 
    Castellanos, Nazareth; Diez, Gustavo-G; Antúnez-Almagro, Carmen; Bailén, María; Bressa, Carlo; González-Soltero, Rocío; Pérez, Margarita; Larrosa, Mar (FRONTIERS MEDIA SA, 2020-01-22)
    Physical exercise improves the overall health status by preventing the development of several diseases. In recent years, it has been observed that physical exercise impacts gut microbiota by increasing the presence of ...
  • ALPPS for Locally Advanced Intrahepatic Cholangiocarcinoma: Did Aggressive Surgery Lead to the Oncological Benefit? An International Multi-center Study 
    Li, Jun; Moustafa, Mohamed; Linecker, Michael; Lurje, Georg; Capobianco, Ivan; Baumgart, Janine; Ratti, Francesca; Rauchfuss, Falk; Balci, Deniz; Fernandes, Eduardo; Montalti, Roberto; Robles-Campos, Ricardo; Bjornsson, Bergthor; Topp, Stefan-A; Fronek, Jiri; Liu, Chao; Wahba, Roger; Bruns, Christiane; Brunner, Stefan-M; Schlitt, Hans-J; Heumann, Asmus; Stueben, Bjoern-Ole; Izbicki, Jakob-R; Bednarsch, Jan; Gringeri, Enrico; Fasolo, Elisa; Rolinger, Jens; Kristek, Jakub; Hernández-Alejandro, Roberto; Schnitzbauer, Andreas; Nuessler, Natascha; Schoen, Michael-R; Voskanyan, Sergey; Petrou, Athanasios-S; Hahn, Oszkar; Soejima, Yuji; Vicente, Emilio; Castro-Benitez, Carlos; Adam, Rene; Tomassini, Federico; Troisi, Roberto-Ivan; Kantas, Alexandros; Oldhafer, Karl-Juergen; Ardiles, Victoria; de-Santibanes, Eduardo; Malago, Massimo; Clavien, Pierre-Alain; Vivarelli, Marco; Settmacher, Utz; Aldrighetti, Luca; Neumann, Ulf; Petrowsky, Henrik; Cillo, Umberto; Lang, Hauke; Nadalin, Silvio (SPRINGER, 2020-05)
    BACKGROUND: ALPPS is found to increase the resectability of primary and secondary liver malignancy at the advanced stage. The aim of the study was to verify the surgical and oncological outcome of ALPPS for intrahepatic ...
  • An Experimental Pilot Study of Global Postural Reeducation Concerning the Cognitive Approach of Patients With Alzheimer's Disease 
    Todri, Jasemin; Lena, Orges; Martínez-Gil, José-Luis (SAGE PUBLICATIONS INC, 2020)
    BACKGROUND: Several recent studies have examined the positive effects of physical exercise and equilibrium on individuals with neurodegenerative diseases. OBJECTIVES: In this sense, this study based on an experimental ...
  • Controlled donation after circulatory death up to 80 years for liver transplantation: Pushing the limit again 
    Cascales-Campos, Pedro-A; Ferreras, David; Alconchel, Felipe; Febrero, Beatriz; Royo-Villanova, Mario; Martínez, María; Rodríguez, José-M; Fernández-Hernández, Juan-A; Ríos-Zambudio, Antonio; Pons, José-A; Sánchez-Bueno, Francisco; Robles-Campos, Ricardo; Martínez-Barba, Enrique; Martínez-Alarcón, Laura; Parrilla, Pascual; Ramírez, Pablo (WILEY, 2020-01)
    Our main objective was to compare liver transplant (LT) results between donation after circulatory death (DCD) and donation after brainstem death (DBD) in our hospital and to analyze, within the DCD group, the influence ...
  • Trends in hospitalisation for ischaemic stroke in young adults in the region of Murcia (Spain) between 2006 and 2014 
    Maldonado-Cárceles, A-B; Hernando-Arizaleta, Lauro; Palomar-Rodríguez, J-A; Morales-Ortiz, A (ELSEVIER ESPANA SLU, 2022-09)
    INTRODUCTION: Recent studies conducted in Europe and the United States suggest upward trends in both incidence and hospitalisation rates for ischaemic stroke in young adults; however, data for Spain are scarce. This study ...
  • Consensus statement on the use of alemtuzumab in daily clinical practice in Spain 
    Meca-Lallana, J-E; Fernández-Prada, M; García-Vázquez, E; Moreno-Guillén, S; Otero-Romero, S; Rus-Hidalgo, M; Villar-Guimerans, L-M; Eichau-Madueno, S; Fernández-Fernández, O; Izquierdo-Ayuso, G; Álvarez-Cermeno, José-C; Arnal-García, C; Arroyo-González, R; Brieva-Ruiz, L; Calles-Hernández, C; García-Merino, A; González-Platas, M; Hernández-Pérez, M-A; Moral-Torres, E; Olascoaga-Urtaza, J; Oliva-Nacarino, P; Oreja-Guevara, C; Ortiz-Castillo, R; Oterino, A; Prieto-González, J-M; Ramio-Torrenta, L; Rodríguez-Antiguedad, A; Saiz, A; Tintore, M; Montalban-Gairin, X (ELSEVIER ESPANA SLU, 2022-10)
    INTRODUCTION: Alemtuzumab is a highly effective drug approved by the European Medicines Agency as a disease-modifying drug for the treatment of relapsing-remitting multiple sclerosis. OBJECTIVE: A consensus document was ...
  • Neoplastic meningitis in solid tumours: Updated review of diagnosis, prognosis, therapeutic management, and future directions 
    García-Molina, E; Penas-Prado, M (ELSEVIER ESPANA SLU, 2022-11)
    Neoplastic meningitis (NM) is a relatively frequent metastatic complication of cancer associated with high levels of neurological morbidity and generally poor prognosis. It appears in 5%-15% of patients with solid tumours, ...
  • Effectiveness of an Interdisciplinary Program Performed on Obese People Regarding Nutritional Habits and Metabolic Comorbidity: A Randomized Controlled Clinical Trial 
    Fernández-Ruiz, Virginia-Esperanza; Ramos-Morcillo, Antonio-Jesús; Sole-Agusti, María; Paniagua-Urbano, José-Antonio; Armero-Barranco, David (MDPI, 2020-01)
    Obesity is an important public health problem. The combined use of different therapies performed by an interdisciplinary group can improve the management of this health issue. The main goal of this research is to determine ...
  • Study protocol for a phase II, multicentre, prospective, non-randomised clinical trial to assess the safety and efficacy of infusing allogeneic activated and expanded natural killer cells as consolidation therapy for paediatric acute myeloblastic leukaemia 
    Muñoz-Builes, Mario; Vela-Cuenca, María; Fuster-Soler, José-L; Astigarraga, Itziar; Pascual-Martínez, Antonia; Vagace-Valero, José-M; Tong, Hoi-Y; Valentin-Quiroga, Jaime; Fernández-Casanova, Lucia; Escudero-López, Adela; Sisinni, Luisa; Blanquer, Miguel; Mirones-Aguilar, Isabel; González-Martínez, Berta; Borobia, Alberto-M; Pérez-Martínez, Antonio (BMJ PUBLISHING GROUP, 2020-01)
    INTRODUCTION: Acute myeloblastic leukaemia (AML) constitutes the second most common haematological malignancy in the paediatric population. Current treatment regimens are based on the administration of polychemotherapy, ...
  • Experience with tocilizumab in patients with neuromyelitis optica spectrum disorders 
    Carreon-Guarnizo, Ester; Hernández-Clares, R; Castillo-Trivino, T; Meca-Lallana, V; Arocas-Casan, V; Iniesta-Martínez, F; Olascoaga-Urtaza, J; Meca-Lallana, J-E (ELSEVIER ESPANA SLU, 2022-04)
    INTRODUCTION: Neuromyelitis optica spectrum disorders (NMOSD) are immune-mediated inflammatory disorders of the central nervous system involving astrocytes, B lymphocytes, anti-aquaporin 4, and such inflammatory mediators ...
  • Sagittal spinal morphotype assessment in 8 to 15 years old Inline Hockey players 
    Sainz-de-Baranda, Pilar; Cejudo, Antonio; Moreno-Alcaraz, Victor-Jesús; Martínez-Romero, María-Teresa; Aparicio-Sarmiento, Alba; Santonja-Medina, Fernando (PEERJ INC, 2020-01-02)
    BACKGROUND: Physiological sagittal spinal curvatures play an important role in health and performance in sports. For that reason, several scientific studies have assessed spinal morphology in young athletes. However, to ...
  • A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia 
    Arriazu, Elena; Vicente, Carmen; Pippa, Raffaella; Peris, Irene; Martínez-Balsalobre, Elena; García-Ramírez, Patricia; Marcotegui, Nerea; Igea, Ana; Alignani, Diego; Rifon, José; Mateos, María-C; Cayuela, María-Luisa; Nebreda, Ángel-R; Odero, María-D (NATURE PUBLISHING GROUP, 2020-01-08)
    Acute myeloid leukemia (AML) is an aggressive hematologic malignancy. Although novel emerging drugs are available, the overall prognosis remains poor and new therapeutic approaches are required. PP2A phosphatase is a key ...
  • Efficacy and safety of D,L-3-hydroxybutyrate (D,L-3-HB) treatment in multiple acyl-CoA dehydrogenase deficiency 
    van-Rijt, Willemijn-J; Jager, Emmalie-A; Allersma, Derk-P; Zeybek, A-Cigdem-Aktuglu; Bhattacharya, Kaustuv; Debray, Francois-Guillaume; Ellaway, Carolyn-J; Gautschi, Matthias; Geraghty, Michael-T; Gil-Ortega, David; Larson, Austin-A; Moore, Francesca; Morava, Eva; Morris, Andrew-A; Oishi, Kimihiko; Schiff, Manuel; Scholl-Buergi, Sabine; Tchan, Michel-C; Vockley, Jerry; Witters, Peter; Wortmann, Saskia-B; van-Spronsen, Francjan; Van-Hove, Johan-L-K; Derks, Terry-G-J (ELSEVIER SCIENCE INC, 2020-05)
    PURPOSE: Multiple acyl-CoA dehydrogenase deficiency (MADD) is a life-threatening, ultrarare inborn error of metabolism. Case reports described successful D,L-3-hydroxybutyrate (D,L-3-HB) treatment in severely affected MADD ...
  • Association of Body Mass Index With Clinical Outcomes in Patients With Atrial Fibrillation: A Report From the FANTASIIA Registry 
    Bertomeu-González, Vicente; Moreno-Arribas, José; Esteve-Pastor, María-Asuncion; Roldán-Rabadán, Inmaculada; Muniz, Javier; Rana-Miguez, Paula; Ruiz-Ortiz, Martín; Cequier, Ángel; Bertomeu-Martínez, Vicente; Badimon, Lina; Anguita, Manuel; Lip, Gregory-Y-H; Marín, Francisco (WILEY, 2020-01-07)
    Background Obesity and atrial fibrillation (AF) frequently coexist and independently increase mortality. We sought to assess the association between obesity and adverse events in patients receiving oral anticoagulants for ...
  • Spanish Cell Therapy Network (TerCel): 15 years of successful collaborative translational research 
    Sánchez-Guijo, Fermin; García-Olmo, Damian; Prosper, Felipe; Martínez, Salvador; Zapata, Agustin; Fernández-Aviles, Francisco; Toledo-Aral, Juan-José; Torres, Miguel; Farinas, Isabel; Badimon, Lina; Labandeira-García, José-Luis; García-Sancho, Javier; Moraleda, José-María (ELSEVIER SCI LTD, 2020-01)
    In the current article we summarize the 15-year experience of the Spanish Cell Therapy Network (TerCel), a successful collaborative public initiative funded by the Spanish government for the support of nationwide translational ...
  • Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease 
    Sánchez-Campillo, María; Ruiz-Pastor, María-José; Gazquez, Antonio; Marín-Muñoz, Juan; Noguera-Perea, Fuensanta; Ruiz-Alcaraz, Antonio-J; Manzanares-Sánchez, Salvadora; Antúnez-Almagro, Carmen; Larque, Elvira (MDPI, 2020-01-01)
    The protein Major Facilitator Superfamily Domain containing 2A (MFSD2a) was recently described as the primary carrier for docosahexaenoic acid (DHA) into the brain. Alzheimer's disease (AD) is a progressive neurodegenerative ...

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