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Envíos recientes

02.01. Área de Salud I Murcia Oeste: Envíos recientes

  • Comprehensive long-term efficacy and safety of recombinant human alpha-mannosidase (velmanase alfa) treatment in patients with alpha-mannosidosisKeywords 
    Lund, Allan-M; Borgwardt, Line; Cattaneo, Federica; Ardigo, Diego; Geraci, Silvia; Gil-Campos, Mercedes; de-Meirleir, Linda; Laroche, Cecile; Dolhem, Philippe; Cole, Duncan; Tylki-Szymanska, Anna; López-Rodríguez, Mónica; Guillén-Navarro, Encarna; Dali, Christine-I; Heron, Benedicte; Fogh, Jens; Muschol, Nicole; Phillips, Dawn; Van-den-Hout, J-M-Hannerieke; Jones, Simon-A; Amraoui, Yasmina; Harmatz, Paul; Guffon, Nathalie (SPRINGER, 2018-12)
    INTRODUCTION: Long-term outcome data provide important insights into the clinical utility of enzyme replacement therapies. Such data are presented for velmanase alfa in the treatment of alpha-mannosidosis (AM). METHODS: ...
  • Patients' and professionals' preferences in terms of the attributes of home enteral nutrition products in Spain. A discrete choice experiment 
    Olveira, Gabriel; Martínez-Olmos, Miguel-Ángel; Fernández-de-Bobadilla, Belén; Ferrer-Gómez, Mercedes; Virgili, Nuria; Vega, Belén; Blanco, Mercedes; Layola, Miquel; Lizan, Luis; Gozalbo, Irmina (NATURE PUBLISHING GROUP, 2018-02)
    BACKGROUND/OBJECTIVES: To elicit and compare preferences in terms of the attributes of home enteral nutrition (HEN) among patients and physicians, using a discrete choice experiment (DCE). SUBJECTS/METHODS: A DCE comprising ...
  • NG2 antigen is a therapeutic target for MLL-rearranged B-cell acute lymphoblastic leukemia 
    López-Millan, Belén; Sánchez-Martínez, Diego; Roca-Ho, Heleia; Gutiérrez-Agüera, Francisco; Molina, Oscar; Díaz-de-la-Guardia, Rafael; Torres-Ruiz, Raul; Fuster-Soler, José-Luis; Ballerini, Paola; Suessbier, Ute; Nombela-Arrieta, Cesar; Bueno, Clara; Menéndez, Pablo (NATURE PUBLISHING GROUP, 2019-07)
    B cell acute lymphoblastic leukemia (B-ALL) is the most common childhood cancer, with cure rates of ?80%. MLL-rearranged (MLLr) B-ALL (MLLr-B-ALL) has, however, an unfavorable prognosis with common therapy refractoriness ...
  • Lytic cell death induced by melittin bypasses pyroptosis but induces NLRP3 inflammasome activation and IL-1ß release 
    Martín-Sánchez, Fatima; Martínez-García, Juan-José; Muñoz-García, María; Martínez-Villanueva, Miriam; Noguera-Velasco, José-Antonio; Andreu, David; Rivas, Luis; Pelegrín, Pablo (NATURE PUBLISHING GROUP, 2017-08)
    The nucleotide-binding domain and leucine-rich repeat-containing receptor with a pyrin domain 3 (NLRP3) inflammasome is a sensor for different types of infections and alterations of homeostatic parameters, including ...
  • Are Environmental Factors for Atopic Eczema in ISAAC Phase Three due to Reverse Causation? 
    Rutter, Charlotte-E; Silverwood, Richard-J; Williams, Hywel-C; Ellwood, Philippa; Asher, Innes; García-Marcos, Luis; Strachan, David-P; Pearce, Neil; Langan, Sinead-M; Ait-Khaled, N; Anderson, H-R; Asher, MI; Beasley, R; Bjorksten, B; Brunekreef, B; Crane, J; Ellwood, P; Flohr, C; Foliaki, S; Forastiere, F; García-Marcos, Luis; Keil, U; Lai, C-K-W; Mallol, J; Mitchell, E-A; Montefort, S; Odhiambo, J; Pearce, N; Robertson, C-F; Stewart, A-W; Strachan, D; von-Mutius, E; Weiland, S-K; Weinmayr, G; Williams, H-C; Wong, G; Clayton, T-O; Ellwood, E; Baena-Cagnani, C-E; Gómez, M; Howitt, M-E; Weyler, J; Pinto-Vargas, R; da-Cunha, A-J; de-Freitas-Souza, L; Kuaban, C; Ferguson, A; Rennie, D; Standring, P; Aguilar, P; Amarales, L; Benavides, L-A; Contreras, A; Chen, Y-Z; Kunii, O; Pan, Q-Li; Zhong, N-S; Aristizabal, G; Cepeda, A-M; Ordóñez, G-A; Bustos, C; Riikjarv, M-A; Melaku, K; Sa'aga-Banuve, R; Pekkanen, J; Hypolite, I-E; Novak, Z; Zsigmond, G; Awasthi, S; Bhave, S; Hanumante, N-M; Jain, K-C; Joshi, M-K; Khatav, V-A; Mantri, S-N; Pherwani, AV; Rego, S; Sabir, M; Salvi, S; Setty, G; Sharma, S-K; Singh, V; Sukumaran, T; Babu, P-S-Suresh; Kartasasmita, C-B; Konthen, P; Suprihati, W; Masjedi, M-R; Steriu, A; Koffi, B-N; Odajima, H; al-Momen, J-A; Imanalieva, C; Kudzyte, J; Quah, B-S; Teh, K-H; Baeza-Bacab, M; Barragan-Meijueiro, M; del-Rio-Navarro, B-E; García-Almaraz, R; González-Díaz, S-N; Linares-Zapien, F-J; Merida-Palacio, JV; Ramírez-Chanona, N; Romero-Tapia, S; Romieu, I; Bouayad, Z; MacKay, R; Moyes, C; Pattemore, P; Onadeko, B-O; Cukier, G; Chiarella, P; Cua-Lim, F; Breborowicz, A; Sole, D; Sears, M; Aguirre, V; Barba, S; Shah, J; Baratawidjaja, K; Nishima, S; de-Bruyne, J; Tuuau-Potoi, N; Lai, C-K; Lee, B-W; El-Sony, A; Anderson, R (ELSEVIER SCIENCE INC, 2019-05)
    Some previously described environmental associations for atopic eczema may be due to reverse causation. We explored the role of reverse causation by comparing individual- and school-level results for multiple atopic eczema ...
  • Models of human psoriasis: Zebrafish the newly appointed player 
    Martínez-Navarro, F-J; Martínez-Menchon, T; Mulero, V; Galindo-Villegas, Jorge (ELSEVIER SCI LTD, 2019-08)
    Psoriasis is a human chronic, immune disease with severe cutaneous and systemic manifestations. Its prevalence, among the world population, highly varies with ethnicity and geography, but not sex from remarkable low levels ...
  • Heterogeneity of Colorectal Cancer Risk Factors by Anatomical Subsite in 10 European Countries: A Multinational Cohort Study 
    Murphy, Neil; Ward, Heather-A; Jenab, Mazda; Rothwell, Joseph-A; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Kvaskoff, Marina; Kaaks, Rudolf; Kuehn, Tilman; Boeing, Heiner; Aleksandrova, Krasimira; Weiderpass, Elisabete; Skeie, Guri; Borch, Kristin-Benjaminsen; Tjonneland, Anne; Kyro, Cecilie; Overvad, Kim; Dahm, Christina-C; Jakszyn, Paula; Sánchez, Maria-Jose; Gil, Leire; Huerta-Castaño, José-María; Barricarte-Gurrea, Aurelio; Quirós, J-Ramón; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn-E; Trichopoulou, Antonia; La-Vecchia, Carlo; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Fasanelli, Francesca; Panico, Salvatore; Bueno-de-Mesquita, Bas; Peeters, Petra-H; Gylling, Bjorn; Myte, Robin; Jirstrom, Karin; Berntsson, Jonna; Xue, Xiaonan; Riboli, Elio; Cross, Amanda-J; Gunter, Marc (ELSEVIER SCIENCE INC, 2019-06)
    BACKGROUND & AIMS: Colorectal cancer located at different anatomical subsites may have distinct etiologies and risk factors. Previous studies that have examined this hypothesis have yielded inconsistent results, possibly ...
  • In-hospital care, complications, and 4-month mortality following a hip or proximal femur fracture: the Spanish registry of osteoporotic femur fractures prospective cohort study 
    Prieto-Alhambra, Daniel; Reyes, Carlen; Sanz-Sainz, Miguel; González-Macías, Jesús; Gracia-Delgado, Luis; Alonso-Bouzon, Cristina; Mills-Ganan, Sarah; Mifsut-Miedes, Damian; Vaquero-Cervino, Eduardo; Bravo-Bardaji, Manuel-Francisco; Ezquerra-Herrando, Laura; Branas-Baztan, Fatima; Llado-Ferrer, Bartolome; Pérez-Coto, Ivan; Adrados-Bueno, Gaspar; Mora-Fernández, Jesús; Espallargas-Donate, Teresa; Martínez-Iniguez-Blasco, Jorge; Aguado-Maestro, Ignacio; Saez-López, Pilar; Salomo-Domenech, Mónica; Climent-Peris, Vicente; Díez-Rodríguez, Ángel; Kessel-Sardinas, Humberto; Tendero-Gómez, Oscar; Teixidor-Serra, Jordi; Caeiro-Rey, José-Ramón; Andrés-Cano, Ignacio; Barres-Carsi, Mariano; Etxebarria-Foronda, Inigo; Avilés-Hernández, Juan-Dionisio; Rodríguez-Solis, Juan; Torregrosa-Suau, Oscar; Nogues, Xavier; Herrera, Antonio; Díez-Pérez, Adolfo (SPRINGER LONDON LTD, 2018-09-14)
    We have characterised 997 hip fracture patients from a representative 45 Spanish hospitals, and followed them up prospectively for up to 4 months. Despite suboptimal surgical delays (average 59.1 hours), in-hospital mortality ...
  • Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4 
    Pizzuto, Malvina; Lonez, Caroline; Baroja-Mazo, Alberto; Martínez-Banaclocha, Helios; Tourlomousis, Panagiotis; Gangloff, Monique; Pelegrín, Pablo; Ruysschaert, Jean-Marie; Gay, Nicholas-J; Bryant, Clare-E (SPRINGER BASEL AG, 2019-09)
    Cardiolipins (CLs) are tetra-acylated diphosphatidylglycerols found in bacteria, yeast, plants, and animals. In healthy mammals, CLs are unsaturated, whereas saturated CLs are found in blood cells from Barth syndrome ...
  • Response-adapted treatment with rituximab, bendamustine, mitoxantrone, and dexamethasone followed by rituximab maintenance in patients with relapsed or refractory follicular lymphoma after first-line immunochemotherapy: Results of the RBMDGELTAMO08 phase II trial 
    Peñalver, Francisco-Javier; Marquez, José-Antonio; Duran, Soledad; Giraldo, Pilar; Martín, Alejandro; Montalban, Carlos; Sancho, Juan-Manuel; Ramírez, Maria-Jose; Terol, Maria-Jose; Capote, Francisco-Javier; Gutiérrez, Antonio; Sánchez, Blanca; López, Andrés; Salar, Antonio; Rodríguez-Caravaca, Gil; Canales, Miguel; Caballero, Maria-Dolores; Bello-López, José-Luis; Carbonell, Felix; Ferrer-Bordas, Secundino; Font-López, Patricia; Pérez-Persona, Ernesto; López-Guillermo, Armando; Hernández-Martín, Roberto; Mayans, José-Ramón; Palomera, Luis; Pérez-Ceballos, Elena; Queizan-Hernández, José-Antonio; Riaza-Grau, Rosalia; de-la-Cruz, Fatima; Sánchez-Salinas, Andrés (WILEY, 2019-11)
    BACKGROUND: Consensus is lacking regarding the optimal salvage therapy for patients with follicular lymphoma who relapse after or are refractory to immunochemotherapy. METHODS: This phase II trial evaluated the efficacy ...
  • Progression-free survival at 2years post-autologous transplant: a surrogate end point for overall survival in follicular lymphoma 
    Jiménez-Ubieto, Ana; Grande, Carlos; Caballero, Dolores; Yanez, Lucrecia; Novelli, Silvana; Hernández, Miguel-T; Manzanares, María; Arranz, Reyes; Ferreiro, José-Javier; Bobillo, Sabela; Mercadal, Santiago; Galego, Andrea; López-Jiménez, Javier; Moraleda-Jiménez, José-María; Vallejo, Carlos; Albo, Carmen; Pérez, Elena; Marrero, Carmen; Magnano, Laura; Palomera, Luis; Jarque, Isidro; Coria, Erika; Rodríguez, Antonia; Martín, Alejandro; López-Guillermo, Armando; Salar, Antonio; Lahuerta, Juan-José (WILEY, 2017-12)
    Overall survival (OS) is the gold-standard end point for studies evaluating autologous stem cell transplantation (ASCT) in follicular lymphoma (FL), but assessment may be elusive due to the lengthy disease course. We ...
  • SMURF: Systematic Methodology for Unveiling Relevant Factors in Retrospective Data on Chronic Disease Treatments 
    Parrales-Bravo, Franklin; del-Barrio-García, Alberto-A; Gago-Veiga, Ana-Beatriz; Gallego-de-la-Sacristana, María-Mercedes; Ruiz-Pinero, Marina; Guerrero-Peral, Ángel; Dzeroski, Saso; Ayala, José-L (IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2019)
  • Effect of different ergonomic supports on muscle activity of dentists during posterior composite restoration 
    López-Nicolás, Manuel; García-Vidal, José-A; Medina-Mirapeix, Francesc; Sánchez-Onteniente, Joaquín-P; Berna-Mestre, Juan-de-Dios; Martín-San-Agustin, Rodrigo; Escolar-Reina, María-P (PEERJ INC, 2019-11-07)
    BACKGROUND: The aim of this study was to evaluate the effect of different ergonomic supports on the muscle activity of two trunk muscles while a group of dentists performed a common dental procedure on a phantom head, ...
  • Age-related differences in flexibility soccer players 8-19 years old 
    Cejudo, Antonio; Robles-Palazón, Francisco-Javier; Ayala-de-la-Peña, Francisco; De-Ste-Croix, Mark; Ortega-Toro, Enrique; Santonja-Medina, Fernando; Sainz-de-Baranda, Pilar (PEERJ INC, 2019-01-29)
  • Enabling Heart Self-Monitoring for All and for AAL-Portable Device within a Complete Telemedicine System 
    Bleda, Andres-Lorenzo; Melgarejo-Meseguer, Francisco-Manuel; Gimeno-Blanes, Juan-Ramón; García-Alberola, Arcadio; Rojo-Álvarez, José-Luis; Corral, Javier; Ruiz, Ricardo; Maestre-Ferriz, Rafael (MDPI, 2019-09-02)
    During the last decades there has been a rapidly growing elderly population and the number of patients with chronic heart-related diseases has exploded. Many of them (such as those with congestive heart failure or some ...
  • Noise Maps for Quantitative and Clinical Severity Towards Long-Term ECG Monitoring 
    Everss-Villalba, Estrella; Melgarejo-Meseguer, Francisco-Manuel; Blanco-Velasco, Manuel; Gimeno-Blanes, Francisco-Javier; Sala-Pla, Salvador; Rojo-Álvarez, José-Luis; García-Alberola, Arcadio (MDPI, 2017-11)
    Noise and artifacts are inherent contaminating components and are particularly present in Holter electrocardiogram (ECG) monitoring. The presence of noise is even more significant in long-term monitoring (LTM) recordings, ...
  • L-Ferritin: One Gene, Five Diseases; from Hereditary Hyperferritinemia to Hypoferritinemia-Report of New Cases 
    Cadenas, Beatriz; Fita-Torro, Josep; Bermudez-Cortés, Mar; Hernández-Rodríguez, Inés; Fuster-Soler, José-Luis; Llinares, María-Esther; Galera-Miñarro, Ana-María; Romero, Julia-Lee; Pérez-Montero, Santiago; Tornador, Cristian; Sánchez, Mayka (MDPI, 2019-01-23)
    Ferritin is a multimeric protein composed of light (L-ferritin) and heavy (H-ferritin) subunits that binds and stores iron inside the cell. A variety of mutations have been reported in the L-ferritin subunit gene (FTL gene) ...
  • Cognitive Training Therapy Improves the Effect of Hypocaloric Treatment on Subjects with Overweight/Obesity: A Randomised Clinical Trial 
    Galindo-Muñoz, Joaquín-S; Morillas-Ruiz, Juana-María; Gómez-Gallego, María; Díaz-Soler, Inmaculada; Barbera-Ortega, María-del-Carmen; Martínez, Carlos-M; Hernández-Morante, Juan-José (MDPI, 2019-04)
    Obesity has been associated with impaired cognitive performance. This study aimed to determine whether improvements in cognitive function may contribute to higher weight loss in patients with obesity. In this randomised, ...
  • Tomato Juice Supplementation Influences the Gene Expression Related to Steatosis in Rats 
    Elvira-Torales, Laura-Inés; Navarro-González, Inmaculada; González-Barrio, Rocío; Martín-Pozuelo, Gala; Domenech, Guillermo; Seva, Juan; García-Alonso, Javier; Periago-Caston, María-Jesús (MDPI, 2018-09)
    The objective of this work was to identify the effect of tomato juice on the expression of genes and levels of metabolites related to steatosis in rats. Male Sprague Dawley rats (8 weeks-old) were grouped (6 rats/group) ...
  • Preclinical Studies of the Biosafety and Efficacy of Human Bone Marrow Mesenchymal Stem Cells Pre-Seeded into ß-TCP Scaffolds after Transplantation 
    Gonzalvez-García, Mar; Martínez, Carlos-M; Villanueva, Víctor; García-Hernández, Ana; Blanquer-Blanquer, Miguel; Meseguer-Olmo, Luis; Oñate-Sánchez, Ricardo-Elías; Moraleda-Jiménez, José-María; Rodríguez-Lozano, Francisco-Javier (MDPI, 2018-08)
    Background: Cell-Based Therapies (CBT) constitute a valid procedure for increasing the quantity and quality of bone in areas with an inadequate bone volume. However, safety and efficacy should be investigated prior to ...

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