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Envíos recientes

02.01. Área de Salud I Murcia Oeste: Envíos recientes

  • Phase II trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/CDKN2A 
    Martín-Broto, Javier; Martínez-García, Jerónimo; Moura, David-S; Redondo, Andrés; Gutiérrez, Antonio; López-Pousa, Antonio; Martínez-Trufero, Javier; Sevilla, Isabel; Diaz-Beveridge, Roberto; Solis-Hernández, María-Pilar; Carnero, Amancio; Pérez, Marco; Marcilla, David; García-Foncillas, Jesús; Romero, Pablo; Fernández-Jara, Javier; López-López, Daniel; Arribas, Ivan; Hindi, Nadia (SPRINGERNATURE, 2023-10)
    Cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors demonstrated activity in terms of progression-free survival (PFS) in advanced dedifferentiated liposarcoma (DD-LPS), a sarcoma with CDK4 amplification. CDK4 overexpression ...
  • Telomerase RNA-based aptamers restore defective myelopoiesis in congenital neutropenic syndromes 
    Martínez-Balsalobre, Elena; García-Castillo, Jesús; García-Moreno, Diana; Naranjo-Sánchez, Elena; Fernández-Lajarin, Miriam; Blasco, María-A; Alcaraz-Pérez, Francisca; Mulero, Víctoriano; Cayuela, María-L (NATURE PORTFOLIO, 2023-09)
    Telomerase RNA (TERC) has a noncanonical function in myelopoiesis binding to a consensus DNA binding sequence and attracting RNA polymerase II (RNA Pol II), thus facilitating myeloid gene expression. The CR4/CR5 domain of ...
  • Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis 
    Zheng, Kang; Hao, Fengjie; Medrano-García, Sandra; Chen, Chaobo; Guo, Feifei; Moran-Blanco, Laura; Rodríguez-Perales, Sandra; Torres-Ruiz, Raúl; Peligros, María-Isabel; Vaquero, Javier; Banares, Rafael; del-Moral, Manuel-Gómez; Regueiro, José-R; Martínez-Naves, Eduardo; Mohamed, Mohamed-Ramadan; Gallego-Duran, Rocio; Maya, Douglas; Ampuero, Javier; Romero-Gómez, Manuel; Gilbert-Ramos, Albert; Guixe-Muntet, Sergi; Fernández-Iglesias, Anabel; Gracia-Sancho, Jordi; Coll, Mar; Graupera, Isabel; Gines, Pere; Ciudin, Andreea; Rivera-Esteban, Jesús; Pericas, Juan-M; Frutos, María-Dolores; Molina, Bruno-Ramos; Herranz, José-María; Ávila, Matias-A; Nevzorova, Yulia-A; Fernández-Malave, Edgar; Cubero, Francisco-Javier (SPRINGERNATURE, 2023-08-10)
    Progressive hepatic damage and fibrosis are major features of chronic liver diseases of different etiology, yet the underlying molecular mechanisms remain to be fully defined. N-RAS, a member of the RAS family of small ...
  • Carfilzomib, lenalidomide and dexamethasone followed by a second ASCT is an effective strategy in first relapse multiple myeloma: a study on behalf of the Chronic malignancies working party of the EBMT 
    Tilmont, Remi; Yakoub-Agha, Ibrahim; Eikema, Diderik-Jan; Zinger, Nienke; Haenel, Mathias; Schaap, Nicolaas; Arroyo, Concepcion-Herrera; Schuermans, Christine; Besemer, Britta; Engelhardt, Monika; Kuball, Jurgen; Michieli, Maríagrazia; Schub, Natalie; Wilson, Keith-MO; Bourhis, Jean-Henri; Mateos, María-Victoria; Rabin, Neil; Jost, Edgar; Kroeger, Nicolaus; Moraleda, José-M; Za, Tommaso; Hayden, Patrick-J; Beksac, Meral; Mclornan, Donal; Schoenland, Stefan; Manier, Salomon (SPRINGERNATURE, 2023-11)
    In the setting of a first relapse of multiple myeloma (MM), a second autologous stem cell transplant (ASCT) following carfilzomib-lenalidomide-dexamethasone (KRd) is an option, although there is scarce data concerning this ...
  • Sedation in pediatric palliative care: The role of pediatric palliative care teams 
    Cantero, María-José-Peláez; Asencio, José-Miguel-Morales; Plantagenet-Whyte, Fatima-Parra; Carmona, Moisés-Leyva; Antonelli, Mireille-Rosique; Bigata, Teresa-Gili; Alba, Ricardo-Martino (CAMBRIDGE UNIV PRESS, 2024-08)
    OBJECTIVES: Palliative sedation (PS) consists of the use of drugs to alleviate the suffering of patients with refractory symptoms, through a reduction in consciousness. The aim of this study is to describe the incidence ...
  • EN-DALBACEN 2.0 Cohort: real-life study of dalbavancin as sequential/consolidation therapy in patients with infective endocarditis due to Gram-positive cocci 
    Hidalgo-Tenorio, Carmen; Sadyrbaeva-Dolgova, Svetlana; Enríquez-Gómez, Andrés; Muñoz, Patricia; Plata-Ciezar, Antonio; Miro, José-María; Alarcón, Aristides; Martínez-Marcos, Francisco-Javier; Loeches, Belén; Escrihuela-Vidal, Francesc; Vinuesa, David; Herrero, Carmen; Boix-Palop, Lucía; Arenas, María-del-Mar; Vázquez, Elisa-García; de-las-Revillas, Francisco-Arnaiz (ELSEVIER, 2023-09)
    OBJECTIVES: Infective endocarditis (IE) has high mortality and morbidity and requires long hospital stays to deliver the antibiotic treatment recommended in clinical practice guidelines. We aimed to analyse the health ...
  • Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes 
    Himmelreich, Nastassja; Bertoldi, Maríarita; Alfadhel, Majid; Alghamdi, Malak-Ali; Anikster, Yair; Bao, Xinhua; Bashiri, Fahad-A; Ben-Zeev, Bruria; Bisello, Giovanni; Ceylan, Ahmet-Cevdet; Chien, Yin-Hsiu; Choy, Yew-Sing; Elsea, Sarah-H; Flint, Lisa; García-Cazorla, Ángels; Gijavanekar, Charul; Guemues, Emel-Yilmaz; Hamad, Muddathir-H; Hismi, Burcu; Honzik, Tomás; Huebschmann, Oya-Kuseyri; Hwu, Wuh-Liang; Ibáñez-Mico, Salvador; Jeltsch, Kathrin; Julia-Palacios, Natalia; Kasapkara, Cigdem-Seher; Kurian, Manju-A; Kusmierska, Katarzyna; Liu, Ning; Ngu, Lock-Hock; Odom, John-D; Ong, Winnie-Peitee; Opladen, Thomas; Oppeboen, Mari; Pearl, Phillip-L; Pérez, Belén; Pons, Roser; Rygiel, Agnieszka-Magdalena; Shien, Tan-Ee; Spaull, Robert; Sykut-Cegielska, Jolanta; Tabarki, Brahim; Tangeraas, Trine; Thoeny, Beat; Wassenberg, Tessa; Wen, Yongxin; Yakob, Yusnita; Yin, Jasmine-Goh-Chew; Zeman, Jiri; Blau, Nenad (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2023-07)
    Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive genetic disorder affecting the biosynthesis of dopamine, a precursor of both norepinephrine and epinephrine, and serotonin. Diagnosis is ...
  • Rats conserve passive avoidance retention level throughout the light phase of diurnal cycle 
    Popovic, Natalija; Morales-Delgado, Nicanor; de-la-Cruz-Sánchez, Ernesto; Popovic, Miroljub (PERGAMON-ELSEVIER SCIENCE LTD, 2023-09)
    Emotions and memory formation are sensible to circadian rhythm. Here we study whether the time of day during the light phase of the diurnal cycle affects emotional memory in male Wistar rats using the passive avoidance ...
  • Impact of particulate matter on the incidence of atrial fibrillation and the risk of adverse clinical outcomes: A review 
    Mandaglio-Collados, Dario; López-Gálvez, Raquel; Ruiz-Alcaraz, Antonio-José; López-García, Cecilia; Roldán-Schilling, Vanesa; Lip, Gregory-YH; Marín, Francisco; Rivera-Caravaca, José-Miguel (ELSEVIER, 2023-07)
    BACKGROUND: Atrial fibrillation (AF) is common and increases the risk of stroke and mortality. Previous studies have suggested that air pollution is an important risk factor for new-onset AF. Herein, we review the evidence ...
  • One-year breakthrough SARS-CoV-2 infection and correlates of protection in fully vaccinated hematological patients 
    Luis-Pinana, José; Vázquez, Lourdes; Calabuig, Marisa; López-Corral, Lucía; Martín-Martín, Gabriel; Villalon, Lucía; Sanz-Linares, Gabriela; Conesa-García, Venancio; Sánchez-Salinas, Andrés; Gago, Beatriz; Facal, Ana; Risco-Galvez, Irene; Olave, María-T; Espigado, Ildefonso; López-Jiménez, Javier; Ángel-Hernández-Rivas, José; Avendano-Pita, Alejandro; Arroyo, Ignacio; Ferrer, Elena; García-Cadenas, Irene; González-Santillana, Clara; Roldan-Pérez, Alicia; Ferrer, Blanca; Guerreiro, Manuel; Suarez-Lledo, María; Camara, Ángela; Campos-Beltran, Diana; Navarro, David; Cedillo, Ángel; Sureda, Anna; Solano, Carlos; Martino, Rodrigo (SPRINGERNATURE, 2023-01-05)
    The long-term clinical efficacy of SARS-CoV-2 vaccines according to antibody response in immunosuppressed patients such as hematological patients has been little explored. A prospective multicenter registry-based cohort ...
  • Use of fluorescence imaging and indocyanine green during thyroid and parathyroid surgery: Results of an intercontinental, multidisciplinary Delphi survey 
    Dip, Fernando; Alesina, Piero-Francesco; Anuwong, Angkoon; Arora, Eham; Berber, Eren; Bonnin-Pascual, Jamie; Bouvy, Nicole-D; Demarchi, Marco-Stefano; Falco, Jorge; Hallfeldt, Klaus; Lee, Kang-Dae; Lyden, Melanie-L; Maser, Christina; Moore, Edwina; Papavramidis, Theodossis; Phay, John; Rodríguez, José-M; Seeliger, Barbara; Solorzano, Carmen-C; Triponez, Frederic; Vahrmeijer, Alexander; Rosenthal, Raúl-J; White, Kevin-P; Bouvet, Michael (MOSBY-ELSEVIER, 2022-12)
    BACKGROUND: In recent years, fluorescence imaging-relying both on parathyroid gland autofluorescence under near-infrared light and angiography using the fluorescent dye indocyanine green-has been used to reduce risk of ...
  • Consensus document on autosomal dominant polycystic kindey disease from the Spanish Working Group on Inherited Kindey Diseases. Review 2020 
    Ars, Elisabet; Bernis, Carmen; Fraga, Gloria; Furlano, Mónica; Martínez, Victor; Martins, Judith; Ortiz, Alberto; Vanessa-Pérez-Gómez, María; Carlos-Rodríguez-Pérez, José; Sans, Laia; Torra, Roser (SOC ESPANOLA NEFROLOGIA DR RAFAEL MATESANZ, 2022-07)
    Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent cause of genetic renal disease and accounts for 6-10% of patients on kidney replacement therapy (KRT). Very few prospective, randomized trials or ...
  • Identification of ALK-positive patients with advanced NSCLC and real-world clinical experience with crizotinib in Spain (IDEALK study) 
    Aguado-de-la-Rosa, Carlos; Cruz-Castellanos, Patricia; Lázaro-Quintela, Martín; Domine, Manuel; Vázquez-Estevez, Sergio; López-Vivanco, Guillermo; Firvida-Pérez, José-Luis; Alonso-Romero, José-Luis; Ferrera-Delgado, Lioba; García-Giron, Carlos; Diz-Tain, Pilar; Álvarez-Álvarez, Rosa; Sanchis, Pilar-Mut; Fernández-Canton, Inmaculada; Manrique-Abos, Isabel; Martínez-Aguillo, Maite; Gómez-Aldaravi-Gutiérrez, Lorenzo; Ortega-Granados, Ana-Laura; Álvarez-Cabellos, Ruth; García-Sebastian, Arancha; García-Sifuentes, Luis-Fernando; Reguart, Noemi (ELSEVIER IRELAND LTD, 2022-11)
    OBJECTIVES: To determine the incidence of ALK translocations in patients with advanced/metastatic NSCLC in Spain, to describe the clinical characteristics of these patients, and to evaluate the effectiveness and safety of ...
  • Live donor kidney transplantation. Situation analysis and roadmap 
    de-la-Oliva-Valentin, María; Hernández, Domingo; Crespo, Marta; Mahillo, Beatriz; Beneyto, Isabel; Martínez, Itziar; Kanter, Julia; Calderari, Elena; Gil-Vernet, Salvador; Sánchez, Sara; Luisa-Aguera, María; Bernal, Gabriel; de-Santiago, Carlos; Diaz-Corte, Carmen; Diaz, Candido; Espinosa, Laura; Facundo, Carme; Fernández-Lucas, Milagros; Ferreiro, Tamara; García-Erauzkin, Gorka; García-Álvarez, Teresa; Fraile, Pilar; González-Rinne, Ana; José-González-Soriano, María; González, Esther; Gutiérrez-Dalmau, Alex; Jiménez, Carlos; Lauzurica, Ricardo; Lorenzo, Inmaculada; Martín-Moreno, Paloma-L; Moreso, Francesc; Carmen-de-Gracia, María; Pérez-Flores, Isabel; Ramos-Verde, Ana; Revuelta, Ignacio; Luisa-Rodríguez-Ferrero, María; Carlos-Ruiz, Juan; Sánchez-Sobrino, Beatriz; Domínguez-Gil, Beatriz (SOC ESPANOLA NEFROLOGIA DR RAFAEL MATESANZ, 2022-01)
    Living donor kidney transplantation (LDKT) is the best treatment option for end stage renal disease in terms of both patient and graft survival. However, figures on LDKT in Spain that had been continuously growing from ...
  • NT-proBNP Response to Sacubitril/Valsartan in Hospitalized Heart Failure Patients With Reduced Ejection Fraction TRANSITION Study 
    Pascual-Figal, Domingo-Andrés; Wachter, Rolf; Senni, Michele; Bao, Weibin; Noe, Adele; Schwende, Heike; Butylin, Dmytro; Prescott, Margaret-F (ELSEVIER SCI LTD, 2020-10)
    OBJECTIVES: This study examined the effects of sacubitril/valsartan on N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels and determined patient characteristics associated with favorable NT-proBNP reduction ...
  • Clinical Risk Score to Predict Pathogenic Genotypes in Patients With Dilated Cardiomyopathy 
    Escobar-López, Luis; Ochoa, Juan-Pablo; Royuela, Ana; Verdonschot, Job-AJ; Dal-Ferro, Matteo; Espinosa, María-Ángeles; Sabater-Molina, María; Gallego-Delgado, María; Larranaga-Moreira, José-M; García-Pinilla, José-M; Basurte-Elorz, María-Teresa; Rodríguez-Palomares, José-F; Climent, Vicente; Bermúdez-Jiménez, Francisco-J; Mogollon-Jiménez, María-Victoria; López, Javier; Pena-Pena, María-Luisa; García-Álvarez, Ana; López-Abel, Bernardo; Ripoll-Vera, Tomás; Palomino-Doza, Julian; Bayes-Genis, Antoni; Brugada, Ramon; Idiazabal, Uxua; Mirelis, Jesús-G; Domínguez, Fernando; Henkens, Michiel-THM; Krapels, Ingrid-PC; Brunner, Han-G; Paldino, Alessia; Zaffalon, Denise; Mestroni, Luisa; Sinagra, Gianfranco; Heymans, Stephane-RB; Merlo, Marco; García-Pavia, Pablo (ELSEVIER SCIENCE INC, 2022-09)
    BACKGROUND: Although genotyping allows family screening and influences risk-stratification in patients with nonischemic dilated cardiomyopathy (DCM) or isolated left ventricular systolic dysfunction (LVSD), its result is ...
  • Natural History of MYH7-Related Dilated Cardiomyopathy 
    de-Frutos, Fernando; Pablo-Ochoa, Juan; Navarro-Peñalver, Marina; Baas, Annette; Bjerre, Jesper-Vandborg; Zorio, Esther; Mendez, Irene; Lorca, Rebeca; Verdonschot, Job-AJ; Elpidio-García-Granja, Pablo; Bilinska, Zofia; Fatkin, Diane; Fuentes-Canamero, MEugenia; García-Pinilla, José-M; García-Álvarez, María-I; Girolami, Francesca; Barriales-Villa, Roberto; Diez-López, Carles; Lopes, Luis-R; Wahbi, Karim; García-Álvarez, Ana; Rodríguez-Sánchez, Ibon; Rekondo-Olaetxea, Javier; Rodríguez-Palomares, José-F; Gallego-Delgado, María; Meder, Benjamin; Kubanek, Milos; Hansen, Frederikke-G; Alejandra-Restrepo-Cordoba, María; Palomino-Doza, Julian; Ruiz-Guerrero, Luis; Sarquella-Brugada, Georgia; José-Pérez-Pérez, Alberto; José-Bermúdez-Jiménez, Francisco; Ripoll-Vera, Tomás; Rasmussen, Torsten-Bloch; Jansen, Mark; Sabater-Molina, María; Elliot, Perry-M; García-Pavia, Pablo (ELSEVIER SCIENCE INC, 2022-10)
    BACKGROUND: Variants in myosin heavy chain 7 (MYH7) are responsible for disease in 1% to 5% of patients with dilated cardiomyopathy (DCM); however, the clinical characteristics and natural history of MYH7-related DCM are ...
  • Maternal urinary concentrations of bisphenol A during pregnancy are associated with global DNA methylation in cord blood of newborns in the "NELA" birth cohort 
    Navarro-Lafuente, Fuensanta; Adoamnei, Evdochia; Arense-Gonzalo, Julián-J; Prieto-Sánchez, María-T; Sánchez-Ferrer, María-L; Parrado, Antonio; Fernández, Mariana-F; Suarez, Beatriz; López-Acosta, Antonia; Sánchez-Guillamon, Antonio; García-Marcos, Luis; Morales, Eva; Mendiola, Jaime; Torres-Cantero, Alberto-M (ELSEVIER, 2022-09)
    Endocrine disrupting chemicals (EDCs) set a public health risk through disruption of normal physiological processes. The toxicoepigenetic mechanisms of developmental exposure to common EDCs, such as bisphenol A (BPA), are ...
  • Clinical Features and Natural History of Preadolescent Nonsyndromic Hypertrophic Cardiomyopathy 
    Norrish, Gabrielle; Cleary, Aoife; Field, Ella; Cervi, Elena; Boleti, Olga; Ziolkowska, Lidia; Olivotto, Iacopo; Khraiche, Diala; Limongelli, Giuseppe; Anastasakis, Aris; Weintraub, Robert; Biagini, Elena; Ragni, Luca; Prendiville, Terence; Duignan, Sophie; McLeod, Karen; Ilina, María; Fernández, Adrián; Marrone, Chiara; Bokenkamp, Regina; Baban, Anwar; Kubus, Peter; Daubeney, Piers-EF; Sarquella-Brugada, Georgia; César, Sergi; Klaassen, Sabine; Ojala, Tiina-H; Bhole, Vinay; Medrano, Constancio; Uzun, Orhan; Brown, Elspeth; Gran, Ferrán; Sinagra, Gianfranco; Castro, Francisco-J; Stuart, Graham; Yamazawa, Hirokuni; Barriales-Villa, Roberto; García-Guereta, Luis; Adwani, Satish; Linter, Katie; Bharucha, Tara; Gonzales-López, Esther; Siles, Ana; Rasmussen, Torsten-B; Calcagnino, Margherita; Jones, Caroline-B; de-Wilde, Hans; Kubo, Toru; Felice, Tiziana; Popoiu, Anca; Mogensen, Jens; Mathur, Sujeev; Centeno, Fernando; Reinhardt, Zdenka; Schouvey, Sylvie; Elliott, Perry-M; Kaski, Juan-Pablo (ELSEVIER SCIENCE INC, 2022-05)
    BACKGROUND: Up to one-half of childhood sarcomeric hypertrophic cardiomyopathy (HCM) presents before the age of 12 years, but this patient group has not been systematically characterized. OBJECTIVES: The aim of this study ...
  • Delphi consensus on recommendations for the treatment of spinal muscular atrophy in Spain (RET-AME consensus) 
    Pitarch-Castellano, I; Cabrera-Serrano, M; Calvo-Medina, R; Cattinari, MG; Espinosa-García, S; Fernández-Ramos, JA; García-Campos, O; Gómez-Andrés, D; Grimalt-Calatayud, MA; Gutiérrez-Martínez, AJ; Ibáñez-Albert, E; Kapetanovic-García, S; Madruga-Garrido, M; Martínez-Moreno, M; Medina-Cantillo, J; Melian-Suarez, A, I; Moreno-Escribano, A; Munell, F; Nascimento-Osorio, A; Pascual-Pascual, S, I; Povedano, M; Santana-Casiano, IM; Vázquez-Costa, JF (ELSEVIER ESPANA SLU, 2022-04)
    INTRODUCTION: Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by a biallelic mutation of the SMN1 gene, located on the long arm of chromosome 5, and predominantly affects the motor neurons of the anterior ...

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