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02.01. Área de Salud I Murcia Oeste: Envíos recientes

  • Co-mutation signatures are age-dependent and impact the prognosis in NPM1-mutated acute myeloid leukemia: a PETHEMA multicenter study. 
    Gil, José-Vicente; Sargas, Claudia; Ayala, Rosa; Gutiérrez, Norma-Carmen; Pérez-Simon, José-Antonio; Gómez-Casares, María-Teresa; Larrayoz, María-José; Prados-de-la-Torre, Esther; Cano-Ferri, Isabel; Navarro, Irene; Gil, Cristina; Bernal, Teresa; Rodríguez-Arboli, Eduardo; Pérez-Santaolalla, Esther; Colmenares, Rafael; Tormo, Mar; Bergua, Juan; Amigo, María-Luz; Rodríguez-Medina, Carlos; Serrano, Josefina; Oliva, Ana-Yurena; Alonso-Domínguez, Juan-Manuel; Noriega, Víctor; Algarra, Lorenzo; Olave, María-Teresa; García-Pérez, María-José; Couto, Carmen; Almela, Agata; García-Fortes, María; Madrigal, María-Dolores; Hermosin, María-Lourdes; Colorado, Mercedes; García-Boyero, Raimundo; Ibáñez, Francisco; Sole, María; Martínez-Chamorro, Carmen; Mateos, María-Del-Carmen; García-Garay, María-Del-Carmen; Solana-Altabella, Antonio; Martin-Herreros, Beatriz; Martínez-López, Joaquín; Chillón, María-Del-Carmen; Soria, Elena; Bilbao, Cristina; Calasanz, María-José; Sánchez-García, Joaquín; Barragán, Eva; Montesinos, Pau (FERRATA STORTI FOUNDATION, 2026-07-16)
    NPM1-mutated acute myeloid leukemia is genetically heterogeneous, and risk assessment remains focused exclusively on FLT3-ITD despite the potential role of other co-mutations. We retrospectively analyzed 1,360 adults from ...
  • Mutational profile and cardiovascular risk factors impact prognosis in triple-negative essential thrombocythemia 
    Carreño-Tarragona, Gonzalo; Gil-Manso, Rodrigo; Hernández-Boluda, Juan-Carlos; Martínez-Ávila, José-Carlos; Bellosillo, Beatriz; Pérez-López, Raúl; Segura, Adrián; Ferrer-Marín, Francisca; Arellano-Rodrigo, Eduardo; Angona, Anna; García-Gutiérrez, Valentín; Noya, María-Soledad; Blanco, Ángela; Zamora, Lurdes; Navarro, Miguel; Senin, Alicia; Magro, Elena; Pastor-Galan, Irene; Mata-Vázquez, María-Isabel; Morales, María-Luz; Cuevas, Beatriz; Velez, Patricia; Mora, Elvira; Martínez-Bilbao, Cristina; Colmenares, Rafael; Alonso, Juan-Manuel; Pérez-Encinas, Manuel; Caballero-Navarro, Gonzalo; Cortes, Miguel-Ángel; Santaliestra, Marta; Raya, José-María; Blanco-Sánchez, Alberto; Hernández-Rivas, Jesus-María; Martínez-López, Joaquín; Ayala, Rosa; Álvarez-Larran, Alberto (SPRINGERNATURE, 2026-07-13)
    Triple-negative essential thrombocythemia (TN-ET) represents a diagnostic and therapeutic challenge. The aim of the present study was to identify prognostic factors useful for tailoring treatment. 241 TN-ET patients with ...
  • Automatic Evaluation of Small Bowel Cleanliness in Capsule Endoscopy: A Comparative Study of Four Preparations using Artificial Intelligence 
    Nevarez, Andrea; Noorda, Reinier; Alonso-Lazaro, Noelia; Carretero, Cristina; Prieto-de-Frias, César; González-Suárez, Begoña; Giordano, Antonio; Jiménez-García, Victoria-Alejandra; Lorenzo-González, Laura; Caunedo-Álvarez, Ángel; Valle-Muñoz, Julio; García-Vela, Almudena; Lujan-Sanchis, Marisol; Ruiz-Sánchez, Lucía; Sánchez-Ceballos, Francisco; Mendoza-Hernández, Juan-Luis; García-Lledo, Javier; Nogales-Rincon, Óscar; Egea-Valenzuela, Juan; Mesa-López, María-José; Merino-Zubizarreta, Ainara; Estevez-Boullosa, Pamela; Martínez-Turnes, Alfonso; Bustamante-Balen, Marco; Naranjo, Valery; Pons-Beltrán, Vicente (GEORG THIEME VERLAG KG, 2026-07-03)
    Background Diagnostic yield (DY) of small bowel capsule endoscopy (SBCE) is limited by the presence of intestinal content. An objective assessment of the cleanliness grade of the small bowel (SB) is currently lacking. We ...
  • First national study on the ethical dimension of neonatal nursing 
    Jiménez-Flores, Javier; Casado-Rodríguez, Aroa; Fernández-Tunas, María-del-Carmen; Laiz-Rodríguez, Marta-Eva; Salcedo-Madridejos, Ángel; Sánchez-Suárez, Patricia; Lambea-Rueda, Leticia; Torres-López, Lorena; Molina-Ruiz, Cristina; Jiménez-Herrera, María-F; Bazo-Hernández, Leticia (SAGE PUBLICATIONS LTD, 2026-07-08)
    BackgroundNeonatal nursing care requires ethical competence alongside technical expertise. Despite progress in Spain, disparities persist in ethical training and professional autonomy in neonatal units.ObjectiveTo examine ...
  • Landscape of copy number variants in Spanish people with dementia. 
    de-Rojas, Itziar; García-González, Pablo; Olive, Claudia; Puerta, Raquel; Montrreal, Laura; Alegret, Montserrat; Sotolongo-Grau, Óscar; Cano, Amanda; Marquie, Marta; Valero, Sergi; Calero, Miguel; Rabano, Alberto; Pastor, Ana-Belén; del-Ser, Teodoro; Quintela, Inés; Macias, Juan; Corma-Gómez, Anais; Pineda, Juan-A; Franco-Macias, Emilio; Buiza-Rueda, Dolores; Bernal-Sánchez-Arjona, Maria; Royo, José-Luis; Mendoza, Silvia; Lage, Carmen; Antúnez-Almagro, Carmen; Corbaton-Anchuelo, Arturo; Martínez-Larrad, María-Teresa; Díez-Fairen, Mónica; Álvarez, Ignacio; Huerto-Vilas, Raquel; Arias-Pastor, Alfonso; Menendez-González, Manuel; Martínez-Rodríguez, Carmen; Rosas-Allende, Irene; García-Madrona, Sebastián; Frank-García, Ana; Martin-Montes, Ángel; Baquero, Miquel; Pérez-Tur, Jordi; Bullido, María-J; García-Ribas, Guillermo; Álvarez, Victoria; Pinol-Ripoll, Gerard; Pastor, Pau; Rodríguez-Rodríguez, Eloy; García-Alberca, José-María; Mir, Pablo; Real, Luis-M; Medina, Miguel; Saez, María-Eugenia; Carracedo, Ángel; Heneka, Michael-T; Tarraga, Lluis; Boada, Merce; Sánchez-Juan, Pascual; Fernández, M-Victoria; van-der-Lee, Sven-J; Ruiz, Agustin (SPRINGERNATURE, 2026-06-30)
    Recent studies suggest that copy number variants (CNVs) may contribute to the missing heritability of complex diseases such as Alzheimer's disease (AD) and related dementias (ADRD). We performed a CNV analysis using ...
  • ELECLA trial: final results of perioperative chemotherapy with fluoropyrimidine and oxaliplatin in mismatch repair proficient locally advanced colon cancer 
    Arredondo, J; Aliseda, D; Castañón, C; Pastor, E; Tejedor, P; Muinelo, M; Pastor, C; García-Flórez, L; Vigorita, V; Gallarin, I; Montoya, M; Tasende, M; García, F; Rodríguez, P; Ruiz-de-la-Hermosa, A; Simo, V; Álvarez, C; Rodríguez, C; Núñez-Cordoba, JM; Rodríguez, J (ELSEVIER, 2026-07)
    BACKGROUND: The current standard of care for resectable locally advanced colon cancer (LACC) is based on upfront surgery followed by adjuvant chemotherapy (AC). This study aimed to evaluate the safety and efficacy of ...
  • Polyphenols increase circulating lipids but improve LDL particle quality and reduce LDL oxidation in postmenopausal women: metabotype- and age-dependent effects in a randomised, placebo-controlled crossover trial 
    García-Nicolas, María; Jarrin-Orozco, María-Paula; Romo-Vaquero, María; Carrascosa, Concepcion; Avilés-Plaza, Francisco; Martínez-Villanueva, Miriam; Noguera, José-Antonio; Ávila-Gálvez, María-Ángeles; Espin, Juan-Carlos (SPRINGER HEIDELBERG, 2026-08)
    PURPOSE: Menopause increases cardiometabolic risk via dyslipidaemia, oxidative stress, and low-grade inflammation. Polyphenols may modulate these processes, but human evidence is inconsistent. We investigated the effects ...
  • Tracing the pathogenic PLN p.(Arg14del) variant across the globe; more than just a local curiosity 
    van-Drie, Esmee; van-Lint, Freyja-H-M; Zwart, Rob; Wang, Jie; Chen, Yucheng; Postma, Alex-V; Elferink, Martin-G; van-Steenbrugge, Joris-J-M; van-der-Zwaag, Paul-A; Jongbloed, Jan-D-H; Dooijes, Dennis; van-der-Heide, Myrthe-Y-C; Houweling, Arjan-C; Haugaa, Kristina-H; Leren, Ida-Skrinde; Kostareva, Anna; Milting, Hendrik; Nguyen, Thuy-Vy; Huynh, Thuy-Duong-Ho; Chevalier, Philippe; Deliniere, Antoine; Gimeno-Blanes, Juan-Ramón; Sabater-Molina, María; Barriales-Villa, Roberto; Mazzanti, Andrea; Memmi, Mirella; Kuramoto, Yuki; Tabata, Tomoka; Wilde, Arthur-A-M; van-Spaendonck-Zwarts, Karin-Y; van-Tintelen, J-Peter (SPRINGER, 2026-12)
    Studying the global distribution of the pathogenic variant c.40_42delAGA;p.(Arg14del) in the phospholamban (PLN) gene is highly important for raising awareness among healthcare providers and may help uncover factors ...
  • Advances in pig embryo production for cryopreservation, transfer and genome editing 
    Cuello, Cristina; García-Cánovas, Manuela; Torregrosa-fuentes, Marcos; López-jara, Adelina; Parrilla, Inmaculada; Gil, M-Antonia; Martínez, Emilio-A (SOCIETY REPRODUCTION & DEVELOPMENT-SRD, )
    Pig embryo production has emerged as a cornerstone for advancing both agricultural efficiency and biomedical innovation. In vivo-derived embryos remain the gold standard for cryopreservation and embryo transfer due to their ...
  • Intertwin birth weight discordance, mode of delivery, and fetal and neonatal outcomes in twin pregnancies 
    Martínez-Zarco, Ana; Sánchez-Romero, Javier; Blanco-Carnero, José-Eliseo; Crespo-Bañón, Paz; Liandro, Romina-Sol; Pertegal-Ruiz, Miriam; Plasencia-Acevedo, Walter; Nieto-Díaz, Aníbal; de-Paco-Matallana, Catalina (WILEY, 2026-06-13)
    OBJECTIVE: The aim of the present study was to evaluate the association between intertwin birth weight discordance and fetal and neonatal outcomes in twin pregnancies, and to assess its relationship with mode of delivery. ...
  • Zebrafish dspb-/- mutant as a model for non-dilated left ventricular cardiomyopathy: exploring cardiac dysfunction and exercise modulation 
    Munteanu, Serena; Wagih-Gómez, Jesus; Júdez-Serrano, Ángel; Saura-Espín, Daniel; Santos-Mateo, Juan-José; Nicolas-Rocamora, María-Elisa; Gil-Ortuno, Cristina; Bernabé-García, Ángel; Gimeno-Blanes, Juan-Ramón; Cayuela-Fuentes, María-Luisa; Sabater-Molina, María (SPRINGERNATURE, 2026-06-15)
    Truncating variants in the DSP gene are associated with non-dilated left ventricular cardiomyopathy (ND-LVC), characterized by impaired ventricular function without dilation. The influence of physical activity in disease ...
  • Real-world pegcetacoplan treatment of paroxysmal nocturnal hemoglobinuria patients with an unsatisfactory response to prior therapies 
    Vallejo, Carlos; González, Carmen; Gaya, Anna; de-la-Iglesia, Silvia; Tormo, Mar; Benet, Carmen; Lavilla, Esperanza; Fernández, Ana; Beneitez, David; Bonanad, Santiago; Carnicero, Fernando; Díaz, Bianca; González, Fernando-Ataulfo; González-Rodríguez, Ana-Pilar; Hernández, Inés; Martí, Jaime; Melero, Virginia; Morado, Marta; Salido-Fiérrez, Eduardo-José; Sánchez, Piva; Torres, Williana; Vara, Miriam; Vidan, Julia (TAYLOR & FRANCIS LTD, 2026-12-31)
    OBJECTIVES: Terminal complement inhibitors can control intravascular hemolysis in Paroxysmal Nocturnal Hemoglobinuria (PNH) patients, although the hematological response achieved may not persist, and it may become ...
  • A prediction tool for malnutrition and sarcopenia in patients with gastroenteropancreatic neuroendocrine neoplasms: results from NUTRIGETNE (GETNE-S2109) study 
    Argente-Pla, María; Sampedro-Núñez, Miguel-Antonio; García-Carbonero, Rocío; Custodio, Ana; Hernando, Jorge; Suárez, Lorena; Hernández-Rienda, Lorena; Peiro, Inmaculada; Alonso, Vicente; Serrano, Raquel; Valdes, Nuria; Melian, Marcos; Febrero, Beatriz; Biarnes, Josefina; Díaz-Pérez, José-Angel; Molina-Cerrillo, Javier; López, Carlos; Martínez-Olmos, Miguel-Ángel; Merino-Torres, Juan-Francisco; Capdevila, Jaume; del-Olmo-García, Maribel (FRONTIERS MEDIA SA, 2026-05-26)
    INTRODUCTION: Malnutrition and sarcopenia are prevalent among patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs), necessitating simple assessment tools to identify potentially malnourished patients. ...
  • Long-Term Colorectal Cancer Incidence After Adenoma and Serrated Polyp Removal: Results From the Colonprev Trial 
    Cubiella, Joaquín; García-Benito, Carme; Castells, Antoni; Quintero, Enrique; Bujanda, Luis; Castan-Cameo, Susana; Díaz-Tasende, José; Lanas, Ángel; Ono-Ono, Akiko; Frias-Arrocha, Eladio; Hernández, Cristina; Jover, Rodrigo; Andreu, Montserrat; Carballo-Álvarez, Luis-Fernando; Morillas, Juan-Diego; Salas, Dolores; Regueiro-Exposito, Cristina; Dávila-Pinon, Pedro; Díez-Martin, Astrid (WILEY, 2026-06)
    BACKGROUND: The risk of colorectal cancer (CRC) after serrated polyp resection remains unclear, and current surveillance recommendations rely on limited evidence. We evaluated CRC incidence in individuals with advanced ...
  • Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis 
    Rodríguez-Calienes, Aaron; Cruz-Criollo, Leonardo; Kontowicz, Eric; Olive-Gadea, Marta; Diana, Francesco; Kaesmacher, Johannes; Mujanovic, Adnan; Geyik, Serdar; Senadim, Songul; Cervo, Amedeo; Salcuni, Andrea; Piano, Mariangela; Moreu, Manuel; López-Frias, Alfonso; Hassan, Ameer-E; Miller, Samantha; Zapata-Arriaza, Elena; de-Alboniga-Chindurza, Asier; Bergui, Mauro; Molinaro, Stefano; Sousa, Joao-Andre; Gomes, Fabio; Sargento-Freitas, Joao; Alexandre, Andrea; Pedicelli, Alessandro; Hofmeister, Jeremy; Machi, Paolo; Scarcia, Luca; Kalsoum, Erwah; Amorim, José; Meira, Torcato; Renieri, Leonardo; Capasso, Francesco; Romano, Daniele; Barcena-Ruiz, Eduardo; Seoane, David; Abdalkader, Mohamad; Klein, Piers; Nguyen, Thanh-N; da-Camara, Catarina-Perry; Brito, Anderson; Abdelhakim, Nashwa; Fragata, Isabel; Yavagal, Dileep-R; Charles, Jude-H; Rodríguez-Castro, José; Vega, Pedro; Ozdemir, Atilla-Ozcan; Kocabas, Zehra-Uysal; Smajda, Stanislas; Al-Salman, Sadiq; Khalife, Jane; Jovin, Tudor-G; Biraschi, Francesco; Richetti, Francesca; Castro, Pedro; Albuquerque, Luis; Siddiqui, Adnan; Jaikumar, Vinay; Navia, Pedro; Ntoulias, Nikolaos; Psychogios, Marios; Velo, Mariano; Zamarro-Parra, Joaquín; de-Paco, Gonzalo; Ashouri, Yazan; AlMajali, Mohammad; Arenillas, Juan-F; Sierra, Alicia; Romoli, Michele; Marto, Joao-Pedro; Yaghi, Shadi; Ribo, Marc; Tomasello, Alejandro; Requena, Manuel; Ortega-Gutiérrez, Santiago (WILEY, 2026-06-09)
    INTRODUCTION/OBJECTIVE: Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of ...
  • Evaluating total tumor load (TTL) to predict metastasis in four or more axillary lymph nodes in HR +/HER2-breast cancer patients: the TULIP4N+study 
    Zamora, Esther; Piñero-Madrona, Antonio; Sperduti, Isabella; Sapino, Anna; Fougo, José-Luis; Peg, Vicente (SPRINGER INT PUBL AG, 2026-06-06)
    PURPOSE: To validate the predictive value of Total Tumor Load (TTL), based on Cytokeratin 19 (CK19) mRNA copy number measured by OSNA in sentinel lymph nodes (SLNs), and to establish an optimal cut-off for identifying HR ...
  • Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study 
    García-Marcos, Luis; Chiang, Chen-Yuan; Asher, M-Innes; Marks, Guy-B; El-Sony, Asma; Masekela, Refiloe; Bissell, Karen; Ellwood, Eamon; Ellwood, Philippa; Pearce, Neil; Strachan, David-P; Martínez-Torres, A-Elena; Sánchez-Solís, Manuel; Mortimer, Kevin; Morales, Eva (WILEY, 2026-06-04)
    BACKGROUND: Lower-income countries have lower asthma prevalence. However, how differences in human development and inequality can explain changes in the prevalence of asthma and allergic diseases is not known. METHODS: The ...
  • Fingolimod increases cellular resistance to HIV-1 infection and limits viral reservoir size in peripheral CD4+ T-cells 
    Moraga, Elisa; Climent, Nuria; Sánchez-Molina, Alejandro; Vicens-Artes, Sonia; Maleno, María-José; Valero-López, Gabriel; Galera-Peñaranda, Carlos; Ambrosioni, Juan; Miro, José-M; Mallolas, Josep; Albendin-Iglesias, Helena; Alcami, José; Sánchez-Palomino, Sonsoles (PUBLIC LIBRARY SCIENCE, 2026-06-03)
    BACKGROUND: Fingolimod, a treatment for multiple sclerosis (MS), decreases autoreactive lymphocytes by lymph node sequestration. In vitro, fingolimod decreases HIV-1 infection and viral reservoir (VR) through SAMHD1 ...
  • Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy (vol 12, 1321282, 2024) 
    Ribeiro-Constante, Juliana; Tristan-Noguero, Alba; Martínez-Calvo, Fernando-Francisco; Ibáñez-Mico, Salvador; Pena-Segura, José-Luis; Ramos-Fernández, José-Miguel; Moyano-Chicano, María-del-Carmen; Camino-Leon, Rafael; Soto-Insuga, Víctor; González-Alguacil, Elena; Valera-Dávila, Carlos-Valera; Fernández-Jaén, Alberto; Plans, Laura; Camacho, Ana; Visa-Rene, Nuria; Martin-Tamayo-Blazquez, María-del-Pilar; Paredes-Carmona, Fernando; Martí-Carrera, Itxaso; Hernández-Fabián, Aranzazu; Tomás-Davi, Meritxell; Casadesús-Sánchez, Merce; Cuesta-Herraiz, Laura; Fuentes-Pita, Patricia; Bermejo-González, Teresa; O'Callaghan, Mar; Iglesias-Santa-Polonia, Federico-Felipe; Cazorla, María-Rosario; Ferrando-Lucas, María-Teresa; González-Meneses, Antonio; Sala-Coromina, Julia; Macaya, Alfons; Lasa-Aranzasti, Amaia; Cueto-González, Anna-Ma; Valera-Parraga, Francisca; Campistol-Plana, Jaume; Serrano, Mercedes; Alonso, Xenia; del-Castillo-Berges, Diego; Schwartz-Palleja, Marc; Illescas, Sofía; Ramírez-Camacho, Alia; Sans-Capdevila, Óscar; García-Cazorla, Ángeles; Bayes, Alex; Alonso-Colmenero, Itziar (FRONTIERS MEDIA SA, 2026-05-18)
    [This corrects the article DOI: 10.3389/fcell.2024.1321282.].
  • Beta-Thalassemia in Spain: Results From the National Thalassemia Registry and Molecular Analysis of Patients With Transfusion-Dependent Thalassemia 
    Villegas, Ana; Ropero, Paloma; González, Fernando-Ataulfo; Morado, Marta; Menor, María; de-la-Iglesia, Silvia; López-Rubio, Montserrat; Salido-Fiérrez, Eduardo-José; Abio, Mariola; Senent, María-Leonor; Recasens, Valle; Vagace, José-Manuel; Fonte, Cristina; Hernández-Rivas, Jesus-María; Raya, José-María; Rios, Pablo; Peri, Valeria-Luciana; Herrera, Keneth-A; Tenorio, María-Concepción; Lo-Riso, Laura; Tena, Juan; Molina, María-Angustias; Vara, Miriam; Rodríguez, Isabel; Ricard, Pilar; Gómez, Miguel; Dusacovschi, Oana-Popa; Vidan, Julia-María; Groiss, Jorge; Ferre, Oscar; Orbe, Irene; López, Rosa-María; Ugalde, Nazaret; Hidalgo, Manuela-Ines; Hinojosa, Cristina; Rodríguez, Ana-Isabel; Herrera, Esther; Muruzabal, María-Josefa; del-Carmen-Hernández, María; Marco, Josefa-Esperanza; Benavente, Celina (WILEY, 2026-06-02)
    BACKGROUND: Beta-thalassemia is a genetically heterogeneous hemoglobinopathy with marked clinical variability. In Spain, comprehensive nationwide data on transfusion-dependent beta-thalassemia (TDT) remain limited, ...

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