Repositorio Dspace

Envíos recientes

02. Servicio Murciano de Salud (SMS): Envíos recientes

  • Changes in daily routines and health-related quality of life among Spanish older adults after the COVID-19 pandemic: analysis from a gender perspective 
    Cameselle-Lago, Candela; Rico-Blázquez, Milagros; Sánchez-Ruano, Raquel; Ayala, Alba; Pascual-García, Marcos; Solé-Agustí, Maria-Cristina; Gimeno-Pi, Iraida; Echevarria-Echevarria, Aitziber; González-Chorda, Víctor-M; Esteban-Sepulveda, Silvia; Pedraz-Marcos, Azucena; Company-Sancho, María-Consuelo; Cidoncha-Moreno, María-Ángeles; Vidal-Thomas, María-Clara; Taltavull-Aparicio, Joana-María; Moreno-Casbas, María-Teresa (FRONTIERS MEDIA SA, 2025-10-13)
    AIMS: To examine the association between perceived changes in daily routines due to the COVID-19 pandemic and health-related quality of life (HRQoL) among community-dwelling adults aged 75 and older in Spain, through a ...
  • Nature-based interventions reduce physiological stress in children with chronic illnesses: evidence from salivary biomarkers 
    Díaz-Martínez, Francisco; Sanchez-Sauco, Miguel-Felipe; Orenes-Piñero, Esteban; Hernandez-Vera, María-José; Robledano-Aymerich, Francisco; Claudio, Luz; Ortega-García, Juan-Antonio (FRONTIERS MEDIA SA, 2025-12-11)
    INTRODUCTION: Contact with nature is increasingly recognized as an important determinant of public health, yet limited objective evidence exists regarding its benefits for children with chronic illnesses. This study aimed ...
  • Long-term effectiveness, adherence and safety of twice-yearly paliperidone-palmitate long acting-injectable in patients with schizophrenia in Europe: 2-year mirror-image data from the paliperdone-2 per year study (P2Y) 
    Manchado-Perero, Sofía; Rodríguez-Lorente, Ana; García-Pérez, Alba-María; García, Guillermo-Isidro; Forcén-Muñoz, Luis-Alberto; Ovejero-García, Sanitago; Sáez-Povedano, Rocío; González-Galdámez, Ana-Luisa; Mata-Iturralde, Laura; Ramírez-Bonilla, Mariluz; Fuentes-Pérez, Paloma; Ovejas-Catalán, Claudia; Suárez-Pinilla, Paula; Fernández-Abascal, Blanca; Omana-Colmenares, Miguel; Campos-Navarro, María-Pilar; Baca-García, Enrique; Lara-Fernández, Ana; Benavente-López, Sergio; Raya-Platero, Alberto; Barberán-Navalon, Miguel; Sánchez-Alonso, Sergio; Vázquez-Bourgon, Javier; Pappa, Sofia; García-Carmona, Juan-Antonio (FRONTIERS MEDIA SA, 2025-03-04)
    BACKGROUND: LAIs with longer dosing intervals appear to be associated with improved clinical outcomes and added real-world benefits in the management of schizophrenia. Paliperidone palmitate six-monthly (PP6M) LAI provides ...
  • Atezolizumab-induced vanishing bile duct syndrome: a case report 
    Noblejas-Quiles, Carlos-Tomás; Macías-Cerrolaza, José-Antonio; Benítez-Fuentes, Javier-David; López-Gómez, Laura; Sánchez-Cánovas, Manuel; Nevado-Rodríguez, María; Martín-Cascón, Miguel; Vigueras-Campuzano, Isabel; Chaves-Benito, Asunción; Lázaro-Sánchez, Antonio-David (FRONTIERS MEDIA SA, 2025-09-11)
    Vanishing bile duct syndrome (VBDS) is a rare but potentially fatal cause of intrahepatic cholestasis, usually associated with autoimmune, infectious or drug-induced etiologies. We present the first documented case of VBDS ...
  • Real-life evidence of encorafenib plus binimetinib in patients with unresectable advanced or metastatic BRAFV600-mutant melanoma in Spain: the BECARE (GEM-2002) trial 
    Soria, Ainara; Sánchez-Maurino, Pedro; Serrano-Domingo, Juan-José; García-Galindo, Regina; Sequero, Silvia; Gutiérrez-Sanz, Lourdes; Crespo, Guillermo; Díaz-Beveridge, Roberto; Puertolas, Teresa; López, Pedro; Rodríguez, Joaquín-Fra; López-Castro, Rafael; Aguayo, Cristina; Valdivia, Javier; Cunquero-Tomas, Alberto-Jacobo; Benítez, Gretel; Ayala-de-Miguel, Pablo; Espinosa, Enrique; Muñoz-Couselo, Eva; Campos, Begoña; García-Sánchez, Lourdes; Cerezuela-Fuentes, Pablo (FRONTIERS MEDIA SA, 2025-02-26)
    PURPOSE: Combined BRAF/MEK inhibition with encorafenib (E) plus binimetinib (B) has demonstrated efficacy and tolerability in phase III clinical trials, and is the standard of care for advanced/metastatic BRAF(V600)-mutant ...
  • Association between human leukocyte antigen E expression and outcomes in solid tumors: a systematic review and meta-analysis 
    Benítez-Fuentes, Javier-David; Arcilla, Jorge-Bartolome; Lázaro-Sánchez, Antonio-David; de-Luna-Aguilar, Alicia; Mohamed, Kauzar-Mohamed; Guevara-Hoyer, Kissy; Ballestín-Martínez, Pablo; Borregón-Rivilla, Miguel; Fernández-Arias, Asia; Sánchez-Ramon, Silvia; Ocaña, Alberto (FRONTIERS MEDIA SA, 2025-02-24)
    BACKGROUND: Immunotherapy has gained momentum with the discovery of novel antibodies targeting immunosuppressive proteins. HLA-E, a non-classical major histocompatibility complex class I (MHC-I) protein, exhibits ...
  • Addressing common biases in the evaluation of lifetime alcohol consumption patterns and dementia risk: the EPIC-Spain dementia cohort 
    Huerta-Castaño, José-María; Colorado-Yohar, Sandra; Andreu-Reinón, María-Encarnación; Mokoroa, Olatz; Tainta, Mikel; Guevara, Marcela; Gasque, Alba; Castilla, Jesús; Petrova, Dafina; Crous-Bou, Marta; Zamora-Ros, Raúl; Sánchez, María-José; Chirlaque-López, María-Dolores (FRONTIERS MEDIA SA, 2025-10-14)
    BACKGROUND: Alcohol consumption has been described to exhibit a J-shaped relationship with dementia risk, but previous observations may be partly biased due to "sick-quitters" and competing risks of death. OBJECTIVE: To ...
  • Listening effort and stress in tinnitus: a multidimensional approach 
    Giliberto, Giovanna; Itati-Palacio, María; Cartocci, Giulia; Fernández-Villalba, Emiliano; Rossi, Dario; Mínguez-Merlos, Nieves; Botia, María; Cubillana-Herrero, José-Domingo; Ceron, José-Joaquín; Babiloni, Fabio; Herrero, María-Trinidad (FRONTIERS MEDIA SA, 2025-07-07)
    INTRODUCTION: This study investigated the impact of chronic tinnitus on auditory perception, text comprehension, and physiological stress responses, with a focus on sex-related differences. The main objectives were to ...
  • Study protocol for design of a personalized dietary supplement based on the gut microbiota of Alzheimer's patients and evaluation of its effects in a pilot randomized controlled trial 
    Clemente-Velasco, Sara; de-Lucas, Beatriz; Tabone, Mariangela; Bressa, Carlo; González-Soltero, María-del-Rocio; Martínez-López, Sara; Bailen, María; Domínguez-Balmaseda, Diego; Castellanos, Nazareth; Díez, Gustavo-G; Noguera-Perea, María-Fuensanta; Marín-Muñoz, Juan; Sánchez-Alonso, Pilar; Rey, Ana-Isabel; Galvez, Beatriz-G; Larrosa, Mar (FRONTIERS MEDIA SA, 2025-09-23)
    BACKGROUND: Increasing evidence links gut microbiota composition to neurological disorders, including Alzheimer's disease (AD), through the gut-brain axis. Microbial metabolites such as lipopolysaccharide (LPS) and butyrate ...
  • Multi-neuromeric origin of tyrosine hydroxylase-positive neurons within the substantia nigra and ventral tegmental area 
    Ferrán, José-Luis; Lucero-Arteaga, Franco; Ayad, Abdelmalik; Kutsenko, Yevheniy; Alonso, A; Ribeiro-Do-Couto, B; García-Cabezas, M-a; Tseng, Kuei-Y (FRONTIERS MEDIA SA, 2025-05-30)
    During early developmental stages, the brain is divided into three primary regions: the forebrain (prosencephalon), the hindbrain (rhombencephalon), and the spinal cord. These regions are further segmented into transverse ...
  • Gut microbiota and postoperative complications in colorectal surgery and its potential association with intestinal permeability and NLRP6 inflammasome. 
    Buitrago-Ruiz, Manuel; Arias-Sánchez, Celia; Asensio-López, María-Magdalena; Martínez-García, Juan-José; Soria-Aledo, Víctor; Valero-Navarro, Graciela; Cuevas, Santiago (FRONTIERS MEDIA SA, 2026-01-26)
    This manuscript reviews the current evidence describing the relationships between surgical trauma, altered intestinal permeability, dysbiosis, inflammasome activation, and postoperative inflammation in the development of ...
  • Biochemical-molecular-genetic biomarkers in the tear film, aqueous humor, and blood of primary open-angle glaucoma patients (vol 10, 1157773, 2023) 
    Pinazo-Duran, María-D; Zanon-Moreno, Vicente; García-Villanueva, Carolina; Martucci, Alessio; Peris-Martínez, Cristina; Vila-Arteaga, Jorge; García-Medina, José-Javier; Andrés-Blasco, Irene; Gallego-Martínez, Alex; Nucci, Carlo; García-Feijoo, Julián (FRONTIERS MEDIA SA, 2025-08-18)
    [This corrects the article DOI: 10.3389/fmed.2023.1157773.].
  • Donor age as an independent predictor of inferior outcomes after haploidentical hematopoietic cell transplantation in acute myeloid leukemia. Study conducted on behalf of GETH-TC 
    Munarriz, Daniel; Pérez-López, Estefanía; Martín-Rodríguez, Carlos; Luque, Marta; Esquirol, Albert; Martín-Calvo, Carmen; Aparicio, Clara; Peña-Muñoz, Felipe; Heras-Fernando, Inmaculada; Oiartzabal-Ormategi, Itziar; Sáez-Marin, Adolfo-Jesús; Fernández-Luis, Sara; Domínguez-García, Juan-José; Villar-Fernández, Sara; López-Lorenzo, José-Luis; Acosta-Fleitas, Cynthia; González-Rodríguez, Ana-Pilar; García, Lucía; Torrado, Tamara; Filaferro, Silvia; Balsalobre, Pascual; Pascual-Cascon, María-Jesús; Rovira, Montserrat; Queralt-Salas, María (FRONTIERS MEDIA SA, 2025-11-28)
    This study evaluated the impact of donor age on clinical outcomes in 274 patients with acute myeloid leukemia (AML) haplo-HCT using PTCY-based prophylaxis. Median patient age was 53 years, with 42.6% classified as high-risk ...
  • Macrophage activation syndrome-like in multiple myeloma patients treated with the academic CAR-T against BCMA ARI0002h 
    Munarriz, Daniel; Rodríguez-Lobato, Luis-Gerardo; López-Corral, Lucía; Arnaldos-Pérez, Cristina; Cabanas-Perianes, Valentín; López-Muñoz, Nieves; Oliver-Caldes, Aina; Ponce, Juan-Carlos; Reguera, Juan-Luis; Martin, Ana-Africa; Martínez-Cibrian, Nuria; Tovar, Natalia; Delgado, Julio; Guillen, Elena; Varea, Sara; Rodríguez-Otero, Paula; Urbano-Ispizua, Álvaro; Moraleda-Jiménez, José-María; Martínez-López, Joaquín; Mateos, María-Victoria; González-de-la-Calle, Veronica; González-Navarro, Europa-Azucena; Fernández-de-Larrea, Carlos (FRONTIERS MEDIA SA, 2025-10-16)
    BACKGROUND: Chimeric antigen receptor T-cell (CAR-T) therapy targeting B-cell maturation antigen (BCMA) has revolutionized multiple myeloma treatment (MM). However, managing its immune-mediated adverse events, particularly ...
  • Real-world patterns of immunoglobulin replacement therapy for infection prevention in common variable immunodeficiency: a multicenter nationwide study 
    Moral-Moral, Pedro; García-Bustos, Victor; Balastegui-Martin, Héctor; Martínez-Mercader, Sandra; Bracke, Carmen; Mateu, Lourdes; Solanich, Xavier; Antoli, Arnau; Carrillo-Linares, Juan-Luis; Robles-Marhuenda, Ángel; Puchades, Francesc; Peláez-Ballesta, Ana-Isabel; López-Osle, Nuria; Torralba-Cabeza, Miguel-Ángel; Bielsa-Masdeu, Ana-María; Gil-Nino, Jorge; Tornador-Gaya, Nuria; Pascual-Castellanos, Guillem; Sánchez-Martínez, Rosario; Barragán-Casas, José-Manuel; González-García, Andrés; Patier-de-la-Peña, José-Luis; López-Wolf, Daniel; Mora-Rufete, Antonia; Cánovas-Mora, Alba; Cabanero-Navalon, Marta-Dafne (FRONTIERS MEDIA SA, 2025-07-23)
    BACKGROUND AND AIMS: Immunoglobulin replacement therapy (IgRT), administered intravenously (IVIg) or subcutaneously (SCIg), is the cornerstone treatment for patients with Common Variable Immunodeficiency (CVID). Although ...
  • Unveiling altered CD8 T-cell metabolism and homeostatic proliferation behind a low CD4/CD8 ratio in ART-suppressed HIV individuals with normal CD4 recovery 
    Garrido-Rodríguez, Vanesa; Bulnes-Ramos, Ángel; Olivas-Martínez, Israel; Pozo-Balado, María-del-Mar; Tejerina-Picado, Francisco; Gutiérrez, Felix; Marco-Sánchez, Cristina; Tiraboschi, Juan-Manuel; Castillo-Navarro, Antonia-María; Bernal-Morell, Enrique; García-Guerrero, María-C; Puertas, María-C; Peraire, Joaquim; Rull, Anna; Martínez-Picado, Javier; Pacheco, Yolanda-María; CoRIS-Cohort (FRONTIERS MEDIA SA, 2025-09-08)
    BACKGROUND: People living with chronic HIV (PLWH) show immune dysfunction, despite viral suppression and normal CD4 recovery, particularly those with low CD4/CD8 ratios. Subjacent cellular alterations of such a reliable ...
  • Unleashing the power of CAR-M therapy in solid tumors: a comprehensive review 
    Morva, Ahsen; Arroyo-Rodríguez, Ana-Belén; Andreeva, Liudmila; Tapia-Abellán, Ana; Luengo-Gil, Ginés (FRONTIERS MEDIA SA, 2025-06-12)
    Chimeric antigen receptor (CAR) macrophage therapy represents a promising new frontier in cancer immunotherapy, with the potential to overcome the limitations of CAR-T cell approaches, particularly in solid tumours. This ...
  • Early cardiac events after haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide. subanalysis exploring cardiac toxicity conducted on behalf of GETH-TC 
    Pinto, Filipe-R; Cascos, Enric; Pérez-López, Estefanía; Baile-González, Mónica; Martín-Rodríguez, Carlos; Pascual-Cascon, María-Jesús; Luque, Marta; Esquirol, Albert; Martín-Calvo, Carmen; Peña-Muñoz, Felipe; Heras-Fernando, Inmaculada; Oiartzabal-Ormategi, Itziar; Sáez-Marin, Adolfo-Jesús; Fernández-Luis, Sara; Domínguez-García, Juan-José; Villar-Fernández, Sara; López-Lorenzo, José-Luis; Fernández-de-Sanmamed-Girón, Miguel; González-Pinedo, Leslie; García, Lucía; González-Rodríguez, Ana-Pilar; Torrado, Tamara; Filaferro, Silvia; Basalobre, Pascual; López-García, Alberto; Orti, Guillermo; Jurado-Chacón, Manuel; Queralt-Salas, María (FRONTIERS MEDIA SA, 2025-05-01)
    INTRODUCTION: Haploidentical allogeneic hematopoietic cell transplantation (haplo-HCT) using post-transplant cyclophosphamide (PTCY) has become a standard approach for patients lacking HLA-matched donors. While effective ...
  • A zebrafish model of Ifih1-driven Aicardi-Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients (vol 14, 1294766, 2023) 
    Bernal-Bermúdez, Beatriz; Martínez-López, Alicia; Martínez-Morcillo, Francisco-J; Tyrkalska, Sylwia-D; Martínez-Menchón, Teresa; Mesa-del-Castillo, Pablo; Cayuela-Fuentes, María-Luisa; Mulero, Víctoriano; García-Moreno, Diana (FRONTIERS MEDIA SA, 2025-01-06)
    [This corrects the article DOI: 10.3389/fimmu.2023.1294766.].
  • Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care 
    Queralt-Salas, María; Solano, María-Teresa; Baile-González, Mónica; Acera-Gómez, Marina; Fox, Laura; Pérez-Artigas, María-del-Mar; Santamaria, Ana; Quintela-González, María-del-Carmen; Sánchez-Salinas, Andrés; Salmerón-Camacho, Joaquina-María; Illana-alvaro, Veronica; Abdallahi-Lefdil, Zahra; Cornago-Navascues, Javier; Pardo, Laura; Fernández-Luis, Sara; Vega-Suárez, Leddy-Patricia; Villar, Sara; Beorlegui-Murillo, Patricia; Esquirol, Albert; Izquierdo-García, Isabel; Rodríguez-González, Sonia; Mussetti, Alberto; Lavilla-Rubira, Esperanza; López-Marín, Javier; Filaferro, Silvia; Cedillo, Ángel; Bento, Leyre; Sureda, Anna (FRONTIERS MEDIA SA, 2025-01-07)
    INTRODUCTION: This multicenter prospective study sponsored by the Grupo Español de Transplante Hematopoyético y Terapia Celular (GETH-TC) explores the use of frailty assessments in allo-HCT candidates. METHODS: Frailty was ...

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