OBJECTIVE: This analysis describes disease activity, organ damage and health-related quality of life (HRQoL) in patients with active SLE and moderate-to-severe disease activity from the Spanish SLE Prospective Observational ...

Background: Osteoporotic vertebral compression fractures (OVCFs) are the most prevalent manifestation of osteoporotic skeletal disease, associated with severe pain, functional decline, and elevated risk of subsequent ...

Background: Work-related musculoskeletal disorders (WRMSDs) are highly prevalent among orthopaedic surgeons, but procedure-related symptom patterns, symptom intensity, and perceived interference remain incompletely ...

BACKGROUND: Advanced NSCLC patients with ECOG PS ?2 are common, under-represented in pivotal trials, and have inferior outcomes with immune checkpoint inhibitors. EU label coverage for ECOG PS ?2 and PS-based dosing guidance ...

BACKGROUND: This study of people with HIV (PWH) receiving CAB + RPV LAI evaluated its effectiveness, safety, and impact on inflammatory markers, body fat/lean mass distributions, quality of life, sleep, health satisfaction, ...

Relapsing-remitting multiple sclerosis (RRMS) is characterized by neuroaxonal damage, astrogliosis and inflammation. These mechanisms may already be active from early disease stages, underscoring the need for sensitive ...

BACKGROUND: While surveillance drug resistance mutations (SDRMs) remain essential for monitoring transmitted drug resistance (TDR), the clinical impact of transmitted resistance for current first-line regimens has become ...