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Listar por tema "Kaplan-Meier Estimate"

Listar por tema "Kaplan-Meier Estimate"

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  • Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study 
    Conteduca, V; Wetterskog, D; Sharabiani, M-T-A; Grande, E; Fernández-Pérez, M-P; Jayaram, A; Salvi, S; Castellano, D; Romanel, A; Lolli, C; Casadio, V; Gurioli, G; Amadori, D; Font, A; Vazquez-Estevez, S; González-del-Alba, A; Mellado, B; Fernández-Calvo, O; Méndez-Vidal, M-J; Climent, M-A; Duran, I; Gallardo, E; Rodríguez, A; Santander, C; Saez, M-I; Puente, J; Tandefelt, D-Gasi; Wingate, A; Dearnaley, D; Demichelis, F; De-Giorgi, U; González-Billalabeitia, Enrique; Attard, G (OXFORD UNIV PRESS, 2017-07)
    BACKGROUND: There is an urgent need to identify biomarkers to guide personalized therapy in castration-resistant prostate cancer (CRPC). We aimed to clinically qualify androgen receptor (AR) gene status measurement in ...
  • Clinical characteristics of patients with central nervous system relapse in BCR-ABL1-positive acute lymphoblastic leukemia: the importance of characterizing ABL1 mutations in cerebrospinal fluid 
    Sánchez, Ricardo; Ayala, Rosa; Alberto-Alonso, Rafael; Pilar-Martínez, María; Ribera, Jordi; García, Olga; Sánchez-Pina, José; Mercadal, Santiago; Montesinos, Pau; Martino, Rodrigo; Barba, Pere; González-Campos, José; Barrios, Manuel; Lavilla, Esperanza; Gil, Cristina; Bernal, Teresa; Escoda, Lourdes; Abella, Eugenia; Amigo, María-Luz; Moreno, María-José; Bravo, Pilar; Guardia, Ramón; Hernández-Rivas, Jesús-María; García-Guinon, Antoni; Piernas, Sonia; Ribera, Jose-Maria; Martínez-López, Joaquín (SPRINGER, 2017-07)
    We investigated the frequency, predictors, and evolution of acute lymphoblastic leukemia (ALL) in patients with CNS relapse and introduced a novel method for studying BCR-ABL1 protein variants in cDNA from bone marrow (BM) ...
  • Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colorectal cancer (HIPECT4): final analysis of randomized clinical trial 
    Arjona-Sánchez, Álvaro; Gutierrez-Calvo, Alberto; Segura-Sampedro, Juan-J; Morales, Rafael; Pérez-Viejo, Estibalitz; Concepción-Martin, Vanessa; Sánchez-García, Susana; García-Fadrique, Alfonso; Prieto-Nieto, Isabel; Bijelic, Lana; Torres-Melero, Juan; Ramírez-Faraco, María; Prada-Villaverde, Arancha; Carrasco-Campos, Joaquín; Artiles-Armas, Manuel; Villarejo-Campos, Pedro; Ortega-Pérez, Gloria; Boldo-Roda, Enrique; Sánchez-Hidalgo, Juan-M; Casado-Adam, Ángela; Rodríguez-Ortiz, Lidia; Rufián-Andújar, Blanca; Aranda, Enrique; Cano-Osuna, María-T; Díaz-López, César; Romero-Ruiz, Antonio; Vázquez-Borrego, María-Carmen; Rufián-Peña, Sebastián (OXFORD UNIV PRESS, 2026-04)
    BACKGROUND: Despite adjuvant systemic chemotherapy after surgical resection in patients with pT4 stage colon cancer, a high percentage of them will develop peritoneal metastases. Intraoperative hyperthermic intraperitoneal ...
  • Functional PTGS2 polymorphism-based models as novel predictive markers in metastatic renal cell carcinoma patients receiving first-line sunitinib 
    Cebrian, Arancha; Gómez-del-Pulgar, Teresa; Méndez-Vidal, María-José; Gonzalvez, María-Luisa; Lainez, Nuria; Castellano, Daniel; García-Carbonero, Iciar; Esteban, Emilio; Saez, María-Isabel; Villatoro, Rosa; Suárez, Cristina; Carrato, Alfredo; Munarriz-Ferrandiz, Javier; Basterrechea, Laura; García-Alonso, Mirta; González-Larriba, José-Luis; Pérez-Valderrama, Begoña; Cruz-Jurado, Josefina; González-del-Alba, Aranzazu; Moreno, Fernando; Reynes, Gaspar; Rodríguez-Remirez, María; Boni, Valentina; Mahillo-Fernández, Ignacio; Martín, Yolanda; Viqueira, Andrea; García-Foncillas, Jesús (NATURE PORTFOLIO, 2017-01-24)
    Sunitinib is the currently standard treatment for metastatic renal cell carcinoma (mRCC). Multiple candidate predictive biomarkers for sunitinib response have been evaluated but none of them has been implemented in the ...
  • Long-Term Stroke Risk Prediction in Patients With Atrial Fibrillation: Comparison of the ABC-Stroke and CHA2DS2-VASc Scores 
    Rivera-Caravaca, José-Miguel; Roldán-Schilling, Vanessa; Esteve-Pastor, María-Asunción; Valdés-Chavarri, Mariano; Vicente, Vicente; Lip, Gregory-Y-H; Marín, Francisco (WILEY, 2017-07)
    BACKGROUND: The ABC-stroke score (age, biomarkers [N-terminal fragment B-type natriuretic peptide, high-sensitivity troponin], and clinical history [prior stroke/transient ischemic attack]) was proposed to predict stroke ...
  • Neutrophil-lymphocyte ratio in metastatic breast cancer is not an independent predictor of survival, but depends on other variables 
    Ivars-Rubio, Alejandra; Yufera, Juan-Carlos; de-la-Morena, Pilar; Fernández-Sánchez, Ana; Navarro-Manzano, Esther; García-Garre, Elisa; García-Martínez, Elena; Marín-Zafra, Gema; Sánchez-Cánovas, Manuel; García-Torralba, Esmeralda; Ayala-de-la-Peña, Francisco (NATURE PORTFOLIO, 2019-11-18)
    The prognostic impact of neutrophil-lymphocyte ratio (NLR) in metastatic breast cancer (MBC) has been previously evaluated in early and metastatic mixed breast cancer cohorts or without considering other relevant prognostic ...
  • Primary results of the Spanish Cryoballoon Ablation Registry: acute and long-term outcomes of the RECABA study 
    Ferrero-de-Loma-Osorio, Ángel; Cozar, Rocío; García-Alberola, Arcadio; Valles, Ermengol; Barrera, Alberto; Toquero, Jorge; Ormaetxe, José-Miguel; Martínez-Sánchez, Juan; Ruiz-Granell, Ricardo; Bastos-Amador, Pablo; Rubio, José-Manuel; Marti-Amor, Julio; Pascual, Patricia; Molina, Irene; Daniel-Martínez-Alday, Jesús (NATURE PORTFOLIO, 2021-08-26)
    Cryoablation is safe and effective for the treatment of atrial fibrillation (AF) in controlled clinical trials, but contemporary real-world usage and outcomes are limited. The Report of the Spanish Cryoballoon Ablation ...
  • Prognostic utility of serum free light chain ratios and heavy-light chain ratios in multiple myeloma in three PETHEMA/GEM phase III clinical trials 
    López-Anglada, Lucía; Cueto-Felgueroso, Cecilia; Rosinol, Laura; Oriol, Albert; Teruel, Ana-Isabel; López-de-la-Guia, Ana; Bengoechea, Enrique; Palomera, Luis; de-Arriba, Felipe; Mariano-Hernández, José; Granell, Miquel; Peñalver, Francisco-Javier; García-Sanz, Ramón; Besalduch, Juan; González, Yolanda; Benigno-Martínez, Rafael; Teodoro-Hernández, Miguel; Gutiérrez, Norma-C; Puerta, Paloma; Valeri, Antonio; Paiva, Bruno; Blade, Joan; Mateos, Maria-Victoria; San-Miguel, Jesús; Lahuerta, Juan-José; Martínez-López, Joaquín (PUBLIC LIBRARY SCIENCE, 2018-09-07)
    We investigated the prognostic impact and clinical utility of serum free light chains (sFLC) and serum heavy-light chains (sHLC) in patients with multiple myeloma treated according to the GEM2005MENOS65, GEM2005MAS65, and ...
  • Progression-free survival at 2years post-autologous transplant: a surrogate end point for overall survival in follicular lymphoma 
    Jiménez-Ubieto, Ana; Grande, Carlos; Caballero, Dolores; Yanez, Lucrecia; Novelli, Silvana; Hernández, Miguel-T; Manzanares, María; Arranz, Reyes; Ferreiro, José-Javier; Bobillo, Sabela; Mercadal, Santiago; Galego, Andrea; López-Jiménez, Javier; Moraleda-Jiménez, José-María; Vallejo, Carlos; Albo, Carmen; Pérez, Elena; Marrero, Carmen; Magnano, Laura; Palomera, Luis; Jarque, Isidro; Coria, Erika; Rodríguez, Antonia; Martín, Alejandro; López-Guillermo, Armando; Salar, Antonio; Lahuerta, Juan-José (WILEY, 2017-12)
    Overall survival (OS) is the gold-standard end point for studies evaluating autologous stem cell transplantation (ASCT) in follicular lymphoma (FL), but assessment may be elusive due to the lengthy disease course. We ...
  • Proliferation to Apoptosis Tumor Cell Ratio as a Biomarker to Improve Clinical Management of Pre-Malignant and Symptomatic Plasma Cell Neoplasms 
    Vasco-Mogorron, María-A; Campillo, José-Antonio; Periago, Adela; Cabanas-Perianes, Valentín; Berenguer, Mercedes; García-Garay, María-Carmen; Gimeno, Lourdes; Soto-Ramírez, María-F; Martínez-Hernández, María-Dolores; Muro-Pérez, Manuel; Minguela-Puras, Alfredo (MDPI, 2021-04)
    Proliferation and apoptosis of neoplastic cells are prognostic biomarkers in plasma cell neoplasms (PCNs). The prognostic capacity of proliferation to apoptosis ratio (Ratio-PA) in the era of immunomodulatory treatments ...