Repositorio Dspace

Listar por tema "Immunity, Innate"

Listar por tema "Immunity, Innate"

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  • Evolution of LPS recognition and signaling: The bony fish perspective 
    Martínez-López, Alicia; Tyrkalska, Sylwia-D; Alcaraz-Pérez, Francisca; Cabas, Isabel; Candel, Sergio; Martínez-Morcillo, Francisco-J; Sepulcre, María-P; García-Moreno, Diana; Cayuela-Fuentes, María-Luisa; Mulero, Victoriano (ELSEVIER SCI LTD, 2023-08)
    Fish are the most diverse and successful group of vertebrate animals, with about 30,000 species. The study of fish immunity is of great importance for understanding the evolution of vertebrate immunity, as they are the ...
  • SAMHD1 deficiency enhances macrophage-mediated clearance of Salmonella Typhimurium via NF-?B activation in zebrafish 
    Martínez-López, Alicia; Tyrkalska, Sylwia-D; Martínez-Morcillo, Francisco-J; Abenza-Olmos, Constantino; Lozano-Gil, Juan-Manuel; Candel, Sergio; Mulero, Víctoriano; García-Moreno, Diana (FRONTIERS MEDIA SA, 2025-04-25)
    INTRODUCTION: Mutations in the gene encoding the protein containing the sterile alpha motif and the HD domain (SAMHD1) have been implicated in the occurrence of type I interferonopathies. SAMHD1 is also involved in blocking ...
  • Techniques to Study Inflammasome Activation and Inhibition by Small Molecules 
    Angosto-Bazarra, Diego; Molina-López, Cristina; Penin-Franch, Alejandro; Hurtado-Navarro, Laura; Pelegrín, Pablo (MDPI, 2021-03)
    Inflammasomes are immune cytosolic oligomers involved in the initiation and progression of multiple pathologies and diseases. The tight regulation of these immune sensors is necessary to control an optimal inflammatory ...
  • von Willebrand factor links primary hemostasis to innate immunity 
    Drakeford, Clive; Águila, Sonia; Roche, Fiona; Hokamp, Karsten; Fazavana, Judicael; Cervantes, Mariana-P; Curtis, Annie-M; Hawerkamp, Heike-C; Dhami, Sukhraj-Pal-Singh; Charles-Messance, Hugo; Hackett, Emer-E; Chion, Alain; Ward, Soracha; Ahmad, Azaz; Schoen, Ingmar; Breen, Eamon; Keane, Joe; Murphy, Ross; Preston, Roger-JS; O'Sullivan, Jamie-M; Sheedy, Frederick-J; Fallon, Padraic; O'Donnell, James-S (NATURE PORTFOLIO, 2022-11)
    The plasma multimeric glycoprotein von Willebrand factor (VWF) plays a critical role in primary hemostasis by tethering platelets to exposed collagen at sites of vascular injury. Recent studies have identified additional ...