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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Response rate and long-term survival in patients with advanced melanoma: data from the prospective cohort study gem-1801 
    Espinosa, Enrique; Berciano-Guerrero, Miguel-Ángel; Muñoz-Couselo, Eva; Puertolas, Teresa; Manzano, José-Luis; Soria, Ainara; Ayala-de-Miguel, Pablo; Crespo, Guillermo; Gutiérrez-Sanz, Lourdes; Cerezuela-Fuentes, Pablo; Aguado-de-la-Rosa, Carlos; Majem, Margarita; García-Castaño, Almudena; Berrocal, Alfonso; García-Arroyo, Francisco-Ramón; De-la-Borbolla, María-Rodriguez; Bellido, Lorena; Medina-Martínez, Javier; Fernández, Luis-Antonio; Martín-Carnicero, Alfonso; López-Castro, Rafael; Bujosa-Rodríguez, Aída; Jose-Lecumberri, Ma; Guzmán, José-Carlos-Villa; Campos-Balea, Begoña; Rodríguez, Joaquín-Fra; Valdivia-Bautista, Javier; Pérez, Víctor-Navarro; Mujika, Karmele; Corral-Subias, Mónica; Hernández, Berta; Martín-Algarra, Salvador; Márquez-Rodas, Iván (SPRINGER INT PUBL AG, 2025-11-28)
    PURPOSE: Anti-PD-1-based immunotherapy and targeted therapies (TT) are the current standard of care for patients with advanced melanoma. However, some patients die in less than a year from diagnosis and others become ...
  • PARP inhibitors-associated thrombosis in patients with ovarian cancer: a study of the Spanish Society of Medical Oncology (SEOM) thrombosis and cancer group (SEPT, 10.1007/s12094-025-04048-z, 2025) 
    Sánchez-Cánovas, Manuel; López-Robles, Javier; García-Verdejo, Francisco-José; Cacho-Lavin, Diego; Olivares, Helena; Garrido-Fernández, Alberto; Coma-Salvans, Eva; Quintanar-Verduguez, Teresa; Salvador-Coloma, Carmen; Fernández-Garay, David; Cumplido, José-David; Ferrer-Pérez, Ana-Isabel; Carbo-Bague, Anna; Teigell-Muñoz, Francisco-Javier; García-López, Rubén; Martínez-Marín, Andrea; Muñoz-Martín, Andrés-Jesús (SPRINGER INT PUBL AG, 2025-11-03)
  • PARP inhibitors-associated thrombosis in patients with ovarian cancer: a study of the Spanish Society of Medical Oncology (SEOM) thrombosis and cancer group 
    Sánchez-Cánovas, Manuel; López-Robles, Javier; García-Verdejo, Francisco-José; Cacho-Lavin, Diego; Olivares, Helena; Garrido-Fernández, Alberto; Coma-Salvans, Eva; Quintanar-Verduguez, Teresa; Salvador-Coloma, Carmen; Fernández-Garay, David; Cumplido, José-David; Ferrer-Pérez, Ana-Isabel; Carbo-Bague, Anna; Teigell-Muñoz, Francisco-Javier; García-López, Rubén; Martínez-Marín, Andrea; Muñoz-Martín, Andrés-Jesús (SPRINGER INT PUBL AG, 2025-09-07)
    PURPOSE: To determine the real-world incidence and predictive factors for venous and arterial thromboembolic events (VTE/AT) in ovarian cancer patients treated with poly-(ADP-ribose) polymerase inhibitors (iPARP). ...
  • A topical nociceutical formulation ameliorates chemotherapy-induced peripheral neuropathy: a pilot randomized clinical study 
    Servitja, Sonia; Castro-Henriques, María; Álvarez-Busto, Inaki; Diez-Franco, Carlota; Medina-Castillo, Alba; Algarra-García, María-Asunción; López-Miranda, Elena; Lario-Martínez, Margaret; Luengo-Alcázar, María-Isabel; Borregón-Rivilla, Miguel; Davo, Ana; Gasull-Delgado, Anna; Roque-García, Sara; Gonzaga-López, Ana; Poveda-Ferriols, Jesús-Manuel; Pascal, Severine; Mitroi-Marinescu, Ana-María; García-Escolano, Marta; Fernández-Carvajal, Asia; Ferrandiz-Huertas, Clotilde; Ferrer-Montiel, Antonio (SPRINGER INT PUBL AG, 2025-10-01)
    BACKGROUND: Up to 80% of patients undergoing taxanes or platinum-based chemotherapy (CT) develop a peripheral polyneuropathy (CIPN), that affects treatment compliance and quality of life (QoL). CIPN is characterized by a ...
  • Real-world management and outcomes of patients with hepatocellular carcinoma treated with systemic therapy in Spain: a patient cohort from the RETUD gastrointestinal registry 
    López-López, Carlos; Martínez-de-Castro, Eva; Fernández-Montes, Ana; Jiménez-Orozco, Encarnación; López-Peraita, Sandra; Vera, Ruth; Cerdá, Paula; Calvo, Mariona; García-Paredes, Beatriz; de-Mena, Miriam-Lobo; La-Casta, Adelaida; Gallego, Javier; Adeva, Jorge; Cano-Cano, Juana-M; Ruiz-Casado, Ana; Vidal-Tocino, Rosario; García-García, Teresa; Pazo-Cid, Roberto; Rodríguez-Garrote, Mercedes; Sastre, Javier (SPRINGER INT PUBL AG, 2025-08-09)
    PURPOSE: Characterization of the management and outcomes of patients diagnosed with hepatocellular carcinoma (HCC) and treated with systemic therapy who were included in the Spanish gastrointestinal RETUD registry. ...
  • Real-world data on avelumab in first-line maintenance therapy for advanced or metastatic urothelial carcinoma: the SOGUG-AVELUMAB RWD study 
    Fernández, Ovidio; Molina, Aurea; Anido-Herranz, Urbano; Álvarez, Carlos; Girones, Regina; Gajate, Pablo; García-Domínguez, Rocio; Ros-Martínez, Silverio; Puente, Javier; Blasco, Sara; Ore-Arce, Martin; Noguerón-Martínez, Esther; Fernández-Freire, Ana; del-Pozo, Nieves; Cassinello, Javier; Lazaro-Quintela, Martin; Arranz, Fernando; Crespo, Guillermo; Abad, María-Teresa; Llorente, Mar; Sánchez-Hernández, Alfredo; Juan, María-José (SPRINGER INT PUBL AG, 2025-07-09)
    PURPOSE: Maintenance avelumab has shown improved overall survival compared to chemotherapy alone in first-line treatment of advanced urothelial carcinoma. This study evaluates real-world evidence of avelumab as first-line ...
  • Trends in the incidence of brain cancer and the use of mobile phones: analysis of the Spanish Network of Cancer Registries (REDECAN) 
    Galceran, Jaume; Ameijide, Alberto; Canete, Adela; Peris-Bonet, Rafael; López-de-Munain, Arantza; Aizpurua, Amaia; de-la-Cruz, Marta; Sanvisens, Arantza; Sánchez, María-José; Palacios, Isabel; Franch, Paula; Sánchez, Antonia; Guevara, Marcela; Carulla, María; Gutiérrez, Pilar; Sáez, Isabel; Rodríguez, Marta; Alemán, Araceli; Sabater, Consol (SPRINGER INT PUBL AG, 2025-05-14)
    PURPOSE: The association between the use of mobile phones use and the risk of brain cancer remains controversial. The aim of this study is to describe trends in the incidence of central nervous system (CNS) cancers in Spain ...
  • Oncological needs in transgender patients 
    Ayala-de-la-Peña, Francisco; Martínez-Ramos, David; Juan-Vidal, Oscar; Gómez-Balaguer, Marcelino; Miguelez, María; Paez, David; Arrazubi, Virginia; Hinojo-González, Carmen (SPRINGER INT PUBL AG, 2025-04-18)
    Transgender people encounter unique health disparities in oncology. They face substantial barriers in accessing healthcare that are exaggerated by bias/discrimination from healthcare professionals and systems, and ...
  • Management and outcome of children with high-risk neuroblastoma: insights from the Spanish Society of Pediatric Hematology and Oncology (SEHOP) neuroblastoma group on refractory and relapse/progressive disease (Feb, 10.1007/s12094-025-03853-w, 2025) 
    Martínez-de-las-Heras, Blanca; Rubio-Aparicio, Pedro-M; Rubio-San-Simon, Alba; Moreno, Lucas; Mazorra, Paula; López-Almaraz, Ricardo; Llempen-López, Mercedes; Balaguer-Guill, Julia; Segura, Vanessa; Bermudez-Cortés, Mar; Jiménez-García, Irene; Ramal, Desiree; Canete, Adela (SPRINGER INT PUBL AG, 2025-04-09)
  • External validation of a prediction model for bleeding events in anticoagulated cancer patients with venous thromboembolism (PredictAI) 
    Vinuela-Beneitez, María-Carmen; Iglesias-Pérez, Claudia; Ortega-Morán, Laura; García-Escobar, Ignacio; Cacho-Lavin, Diego; Balanya, Rut-Porta-i; García-Adrián, Silvia; Carmona-Campos, Marta; Benítez-López, Gretel; Santiago-Crespo, José-Antonio; Lobo-de-Mena, Miriam; Pérez-Altozano, Javier; Gallardo-Díaz, Enrique; Tejerina-Peces, Julia; Ochoa-Rivas, Pilar; Ortiz-Morales, María-José; Castellón-Rubio, Victoria-Eugenia; Diez-Pedroche, Carmen; Rosales-Sueiro, María; Goncalves, Felipe; Sánchez-Cánovas, Manuel; Ruiz, Miguel-Ángel; Muñoz-Langa, José; Pérez-Segura, Pedro; Martínez-de-Castro, Eva; Carmona-Bayonas, Alberto; Jiménez-Fonseca, Paula; Muñoz-Martín, Andrés-Jesús (SPRINGER INT PUBL AG, 2025-04-26)
    OBJECTIVE: The objective of this study was to validate the PredictAI models for predicting major bleeding (MB) in patients with active cancer and venous thromboembolism (VTE) with anticoagulant (ACO) therapy, within 6 months ...
  • Hospital at home for oncologic patients: SEOM-SEHAD consensus on clinical practice 
    Villegas-Bruguera, Eulalia-B; Molina-Mata, Kevin; Fernandez-Martinez-de-Mandojana, Magdalena; Guillén-Blanco, Iosune; Sánchez-Cánovas, Manuel (SPRINGER INT PUBL AG, 2025-04-23)
    The number of oncologic patients and survival rates are increasing worldwide. This fact implies greater comorbidity and complications associated with cancer and oncologic therapies. Many of these complications require ...
  • Management and outcome of children with high-risk neuroblastoma: insights from the Spanish Society of Pediatric Hematology and Oncology (SEHOP) neuroblastoma group on refractory and relapse/progressive disease 
    Martínez-de-las-Heras, Blanca; Rubio-Aparicio, Pedro-M; Rubio-San-Simon, Alba; Moreno, Lucas; Mazorra, Paula; López-Almaraz, Ricardo; Llempen-López, Mercedes; Balaguer-Guill, Julia; Segura, Vanessa; Bermudez-Cortés, Mar; Jiménez-García, Irene; Ramal, Desiree; Canete, Adela (SPRINGER INT PUBL AG, 2025-02-25)
    PURPOSE: Outcome for children with refractory and relapse/progressive high-risk neuroblastoma (HR-NB) remains poor, without an internationally agreed standard second-line approach. Heterogeneity in patients' disease and ...
  • SEOM-GEIS Spanish clinical guidelines for the management of soft-tissue sarcomas (2024) 
    Serrano, César; Arregui, Marta; Carrasco, Irene; Hindi, Nadia; Martínez-Trufero, Javier; Martínez-García, Jerónimo; Molina, Aurea; Paisan, Ana; Sánchez, Raúl; Sala, María-Ángeles (SPRINGER INT PUBL AG, 2025-02-07)
    Soft-tissue sarcomas are rare, diverse malignant tumors of mesenchymal origin, requiring diagnosis and treatment by a specialized multidisciplinary team. Initial assessment includes radiology and biopsy, followed by wide ...
  • Immune checkpoint inhibitors-associated thrombosis in patients with head and neck cancer: a study of the Spanish society of medical oncology (SEOM) thrombosis and cancer group 
    Sánchez-Cánovas, Manuel; Moya-Hernández, Miguel-Ángel; Adoamnei, Evdochia; Cacho-Lavin, Diego; Fernández-Garay, David; Quintanar-Verduguez, Teresa; Rogado-Revuelta, Jacobo; García-Verdejo, Francisco-José; García-Adrián, Silvia; Ferrer-Pérez, Ana-Isabel; Guirao-García, María-Esperanza; López-Robles, Javier; Mendiola-Olivares, Jaime; Muñoz-Martín, Andrés-Jesús (SPRINGER INT PUBL AG, 2024-06-21)
    PURPOSE: Both venous and arterial thrombotic events (VTE/AT) can be associated with Immune Checkpoint Inhibitors (ICI). However, there is a paucity of information apropos patients in routine clinical practice. METHODS: ...
  • Suicide in adults within 30 days of discharge from hospital emergency department 
    Maestre-Orozco, Tamara; Soriano, Vicente; Sánchez-Gómez, Dolores-Elvira; Espinosa, Begoña; Blasco-Fontecilla, Hilario; Gallego, Lucía; Llorens, Pere; Ramos-Rincon, José-Manuel (SPRINGER-VERLAG ITALIA SRL, 2025-11)
    Suicide remains a frequent cause of death in adults, often overlooked despite known risk factors like mental disorders, older age, and chronic illness. Emergency department visits offer critical opportunities to identify ...
  • The use of oral anticoagulation at the time of acute COVID-19 infection and subsequent development of long-COVID/post-acute sequelae of SARS-CoV-2 infection 
    Frost, Freddy; Rivera-Caravaca, José-Miguel; Lip, Gregory-Y-H (SPRINGER, 2025-04-05)
    Long COVID (LC) or post-acute sequelae of SARS-CoV-2 infection (PASC) is defined as ongoing, relapsing or new symptoms/conditions persisting after an acute COVID-19 infection. Given the potential role of oral anticoagulants ...
  • Real-world clinical outcomes of apalutamide versus abiraterone with androgen deprivation therapy for metastatic hormone-sensitive prostate cancer 
    Pons-Fuster, Eduardo; González-Ponce, Celia-María; Ros-Martínez, Silverio; Fernández-Ávila, Juan-José; Díaz-Carrasco, María-Sacramento; Espuny-Miro, Alberto (SPRINGER, 2025-12)
    BACKGROUND: Metastatic hormone-sensitive prostate cancer (mHSPC) is an aggressive disease with a poor prognosis. Current treatment guidelines recommend combining androgen receptor axis-targeted therapies (ARATs) with ...
  • Infection Spread and Outbreaks Support with Spatial-Temporal Visualization Tool for Hospitals 
    Kim, Denisse; Cánovas-Segura, Bernardo; Campos, Manuel; Alemán-Belando, Sergio; Juárez, José-Manuel (SPRINGER, 2025-06-18)
    Hospital-acquired infections (HAIs), especially those caused by multidrug-resistant bacteria, represent a critical challenge, increasing healthcare costs, hospital stays, and mortality rates. Monitoring HAIs requires ...
  • Novel Insights into the Clinical Features, Genetic Spectrum and Clonal Evolution of Patients Carrying NLRP3 Mosaicism 
    Bonet, Nuria; Mascaro, José-M; Hurtado-Navarro, Laura; Angosto-Bazarra, Diego; Callejas-Rubio, José-Luis; Clemente, Daniel; Souto, Alejandro; Lima, Olalla; Palmou-Fontana, Natalia; Baselga, Eulalia; Jiménez-Trevino, Santiago; Remesal, Agustin; Andreu-Barasoain, Marta; Fernández-Domínguez, Luis; Riera-Monroig, Josep; Aparicio, María; García-Herrero, Juan; Pesque, David; Sánchez-Calvin, María-Teresa; Lezana-Rosales, José-Miguel; Correyero-Plaza, María; García-Villalba, Julio; Bolano, Victor; Peiró, Sara; Díaz, Mar; Vlagea, Alexandru; Lorca, Daniel; Fabregat, Virginia; Anton, María-Carmen; Plaza, Susana; González-Granado, Luis-Ignacio; Postigo, Concepción; García-Ruiz-de-Morales, José-María; Gómez-de-la-Fuente, Enrique; Iglesias, Estibaliz; Gómez-Roman, Javier; Vázquez-Trinanes, Caritina; López-Robledillo, Juan-Carlos; Ortego-Centeno, Norberto; Giménez-Arnau, Ana-María; Campistol, Josep-M; Laayouni, Hafid; Ortiz-de-Landazuri, Iñaki; Yague, Jordi; González-Roca, Eva; Mensa-Vilaro, Anna; Fornas, Oscar; Ramos, Eduardo; Pelegrín, Pablo; Casals, Ferran; Arostegui, Juan-I (SPRINGER/PLENUM PUBLISHERS, 2025-12)
    NLRP3 mosaicism is a well-established mechanism causing the monogenic autoinflammatory disease named cryopyrin-associated periodic syndromes (CAPS). The number of reported patients with NLRP3 mosaicism is small, and the ...
  • Editorial Expression of Concern: Antinociceptive and antiedema effects produced in rats by Brassica oleracea var. italica sprouts involving sulforaphane 
    Guadarrama-Enriquez, Omar; Moreno-Pérez, Gabriel-Fernando; González-Trujano, María-Eva; Angeles-López, Guadalupe-Esther; Ventura-Martínez, Rosa; Díaz-reval, Irene; Cano-Martínez, Agustina; Pellicer, Francisco; Baenas, Nieves; Moreno, Diego-A; García-Viguera, Cristina (SPRINGER BASEL AG, 2026-02)