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Envíos recientes

Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Early Cell Adhesion of Periodontal Ligament Stem Cells on 3D Printed Polylactic Acid/Hydroxyapatite Scaffolds: An In Vitro Study 
    Serrano-Belmonte, Ildefonso; Montero, Javier; Guerrero-González, Elena; Munteanu, Alexandra; Pérez-Fernández, Virginia; Pérez-Silva, Amparo; Martínez-Cánovas, Ascensión (MDPI, 2025-11-20)
    Polylactic acid (PLA) and its composites with hydroxyapatite (HA) have been studied in the field of bone repair applications. The objective of this study was to evaluate the biocompatibility of PLA/HA at different ...
  • Stability Studies of Clonazepam 2.5 mg/mL Oral Solution and 1 mg/mL Parenteral Solution in Pre-Filled Polypropylene Syringes 
    Ruiz-Ramírez, Juan-Carlos; Talsi-Hamdani, Icram; Bermúdez-Gazquez, Laura; Viney, Alice-Charlotte; Alonso-Herreros, José-M (MDPI, 2025-10-07)
    Background: Clonazepam is a benzodiazepine drug indicated in all clinical forms of epileptic seizures, various forms of myoclonic seizures, myoclonus and other abnormal movements. At present, it is classified as a hazardous ...
  • Pharmacokinetics and Childhood Obesity: Pathophysiological Basis and Challenges in Choosing the Ideal Body Size Descriptor 
    Hernández-Gago, Yolanda; Sánchez-Hernández, José-Germán; Alcalá-Minagorre, Pedro-J; Rodríguez-Marrodan, Belén; Hernández-Sabater, Laura; Cabanas-Poy, María-José; Rodríguez-Negrín, Ana-Cristina (MDPI, 2025-12-21)
    Despite the progressive increase in obesity and associated chronic diseases in children, there is limited evidence on the optimal dosage of most medications for obese children and adolescents. This review analyzes the ...
  • Propranolol Administration During Morphine Addiction Attenuates Reinstatement of Drug-Aversive Memories Caused by Exposure to Stressful Stimuli 
    Cánovas-Cabanes, Alberto; Teruel-Fernández, Francisco-Javier; Fernández-López, Lucía; Martínez-Laorden, Elena; Navarro-Zaragoza, Javier; Almela-Rojo, Pilar (MDPI, 2025-12-23)
    Background/Objectives: Situations previously paired with drug use can become conditioned stimuli (i.e., physical stress or psychosocial stress) that elicit intense craving and relapse, even after prolonged abstinence. ...
  • VEGF Signaling Pathway Germline Polymorphisms as Prognostic Pharmacogenetic Biomarkers in Localized High-Grade Osteosarcoma Patients from the GEIS-33 Protocol 
    Salazar, Juliana; Arranz, María-J; Martín-Broto, Javier; Serra, Massimo; Palmerini, Emanuela; Martínez-García, Jerónimo; Juan-Ribelles, Antonio; Andion, Maitane; Martínez-Trufero, Javier; Gutiérrez, Guiomar; Echebarria-Barona, Aizpea; Vaz-Salgado, María-A; Regueiro, Alexandra; Álvarez, Rosa; Valverde, Claudia; Luna, Pablo; Blay, Pilar; Sebio, Ana (MDPI, 2025-12-05)
    Background/Objective: The vascular endothelial growth factor (VEGF) signaling pathway induces angiogenesis, which impacts tumor progression and clinical outcomes in patients with localized osteosarcoma. This study evaluates ...
  • Synergizing Virtual Screening and Zebrafish Models to Identify Resveratrol-Derived Antiaging Polyphenols 
    Hernández-Silva, David; Cabello-Villalba, Cynthia; Cayuela-Fuentes, María-Luisa; Pérez-Sánchez, Horacio; Alcaraz-Pérez, Francisca (MDPI, 2025-10-28)
    Background: Telomere shortening and chronic inflammation are well-established hallmarks of aging and age-related diseases, often resulting in impaired cellular function. Identifying compounds with anti-aging potential is ...
  • Host Genetic Factors in Q Fever Susceptibility 
    Robaina-Bordon, José-María; Pérez-Arellano, José-Luis; Montes-Ares, Olga; Torio-Ruiz, Alberto; Hernández-Cabrera, Michele; Pisos-Alamo, Elena; Carranza-Rodríguez, Cristina (MDPI, 2025-04-18)
    Several indirect findings suggest that host-related factors influence susceptibility to Coxiella burnetii infection. We decided to explore the influence of genetic factors related to both innate and adaptive immunity in ...
  • Enhanced Acute Muscle Activation in ALS Patients Following Liposomal Curcumin, Resveratrol, and Dutasteride Administration 
    Martín-Ruiz, Julio; Maset-Roig, Rosa; Caplliure-Llopis, Jordi; Villaron-Casales, Carlos; Alarcón-Jiménez, Jorge; de-Bernardo, Nieves; Proano, Belén; Menargues-Ramírez, Rubén; Selvi-Sabater, Pablo; de-la-Rubia-Orti, José-Enrique (MDPI, 2025-03-28)
    Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of electrical activity and motor control at the muscular level. Therapeutic alternatives, such as the polyphenolic ...
  • A New Primary Care Model Based on Population Needs: A Nationwide Cross-Sectional Study 
    Domínguez-Fernández, Silvia; García-Martínez, Pedro; Marmol-López, María-Isabel; Nieto-García, Esther; Sánchez-Gómez, María-Begoña; Fontan-Vinagre, M-Guadalupe; Ayuso-Murillo, Diego; Montenegro-Méndez, Susana; Pérez-Rivas, Francisco-Javier (MDPI, 2025-07-08)
    Background/Objectives: The role of the primary health care nurse has evolved since the Spanish Ministry of Health officially established the professional profile of the nurse specialist in Primary Health Care in 2005. ...
  • Mixed Reality in Undergraduate Nursing Education: A Systematic Review and Meta-Analysis of Benefits and Challenges 
    Guillén-Aguinaga, Laura; Rayon-Valpuesta, Esperanza; Guillén-Aguinaga, Sara; Rodríguez-Díaz, Blanca; Montejo, Rocío; Alas-Brun, Rosa; Aguinaga-Ontoso, Enrique; Onambele, Luc; Guillén-Aguinaga, Miriam; Guillén-Grima, Francisco; Aguinaga-Ontoso, Inés (MDPI, 2025-04-22)
    Background: Nursing Schools are incorporating Mixed Reality (MR) into student training to enable them to confront challenging or infrequently encountered scenarios in their practice and ensure their preparedness. This ...
  • Resilience as a Mediator Between Workplace Violence and Psychological Well-Being in Hospital Nurses 
    García-Izquierdo, Mariano; Soler-Sánchez, María-Isabel; de-Haro-García, José-Manuel; Ríos-Rízquez, María-Isabel; Meseguer-de-Pedro, Mariano (MDPI, 2025-06-26)
    Workplace violence is a widespread issue affecting hospital nursing staff and significantly undermines their psychological well-being. Such violence originates from various sources, including users, colleagues, and ...
  • Epidemiological Profile and Risk Factors Related to Sexually Transmitted Infections in Sex Workers in Granada (Spain) 
    Llavero-Molino, Isabel; Sánchez-Torres, María; Hueso-Montoro, César; González-García, Alberto; García-García, Inmaculada; Jiménez-Bautista, Francisco; Pérez-Morente, María-Ángeles (MDPI, 2025-02-28)
    Background: Sex work is one of the oldest trades in the world. It is the practice of sexual activity in exchange for money or material goods. It has traditionally been carried out by women, although in recent years, there ...
  • Polyphenol-Related Gut Metabotype Signatures Linked to Quality of Life in Postmenopausal Women: A Randomized, Placebo-Controlled Crossover Trial 
    Jarrin-Orozco, María-P; Romo-Vaquero, María; Carrascosa, Concepción; Pertegal-Ruiz, Miriam; Berna, José; Puigcerver, Julio; Saura-Sanmartin, Adrián; Espinosa-Salinas, Isabel; García-Nicolás, María; Ávila-Galvez, María-A; Espín, Juan-C (MDPI, 2025-11-15)
    Background/Objectives: Interindividual variability in polyphenol metabolism may help explain the inconsistent effects of polyphenol intake on health outcomes. This study compared, for the first time, (i) polyphenol-related ...
  • Association Between Dietary Intake and Blood Concentrations of One-Carbon-Metabolism-Related Nutrients in European Prospective Investigation into Cancer and Nutrition 
    Park, Jin-Young; Van-Puyvelde, Heleen; Regazzetti, Lea; Clasen, Joanna-L; Heath, Alicia-K; Eussen, Simone; Ueland, Per-Magne; Johansson, Mattias; Biessy, Carine; Zamora-Ros, Raúl; Huerta-Castaño, José-María; Sánchez, María-José; Ocke, Marga; Schulze, Matthias-B; Schiborn, Catarina; Braaten, Tonje-Bjorndal; Skeie, Guri; Sacerdote, Carlotta; Castilla, Jesús; Karlsson, Therese; Johansson, Ingegerd; Kyro, Cecilie; Tjonneland, Anne; Tong, Tammy-Y-N; Katzke, Verena; Bajracharya, Rashmita; Lasheras, Cristina; Midttun, Oivind; Vollset, Stein-Emil; Vineis, Paolo; Masala, Giovanna; Amiano, Pilar; Tumino, Rosario; Baldassari, Iván; Weiderpass, Elisabete; Riboli, Elio; Gunter, Marc-J; Freisling, Heinz; Rinaldi, Sabina; Muller, David-C; Huybrechts, Inge; Ferrari, Pietro (MDPI, 2025-06-10)
    Background/Objectives: We examined the association between dietary intake and blood concentrations of one-carbon metabolism (OCM)-related nutrients in the European Prospective Investigation into Cancer and Nutrition (EPIC). ...
  • Impact of Chronic Nitrate and Citrulline Malate Supplementation on Performance and Recovery in Spanish Professional Female Soccer Players: A Randomized Controlled Trial 
    Ramírez-Munera, Marta; Arcusa, Raúl; López-Román, Francisco-Javier; Ávila-Gandía, Vicente; Pérez-Pinero, Silvia; Muñoz-Carrillo, Juan-Carlos; Luque-Rubia, Antonio-Jesús; Marhuenda, Javier (MDPI, 2025-07-21)
    Background: Pre-season training is critical for developing tolerance to high physical demands in professional soccer, and nitric oxide (NO) precursors such as dietary nitrate (NO(3)(-)) and citrulline malate (CM) can support ...
  • Diabetes-Related Dietary Patterns and Endometrial Cancer Risk and Survival in the European Prospective Investigation into Cancer and Nutrition Study 
    Torres-Laiton, Luisa; Luján-Barroso, Leila; Nadal-Zaragoza, Nuria; Castro-Espín, Carlota; Jakszyn, Paula; Panico, Camilla; Le-Cornet, Charlotte; Dahm, Christina-C; Petrova, Dafina; Rodríguez-Palacios, Daniel; Jannasch, Franziska; Masala, Giovanna; Dossus, Laure; Padroni, Lisa; Guevara, Marcela; Schulze, Matthias-B; Fortner, Renee-Turzanski; Tumino, Rosario; Crous-Bou, Marta (MDPI, 2025-05-12)
    BACKGROUND/OBJECTIVES: Endometrial cancer (EC)'s major risk factors include obesity and diabetes, both strongly related with lifestyle choices and dietary factors. Our study aimed to evaluate the relationship between ...
  • Association of Dietary Advanced Glycation End Products with Overall and Site-Specific Cancer Risk and Mortality: A Systematic Review and Meta-Analysis 
    Pascual-Morena, Carlos; Garrido-Miguel, Miriam; Martínez-García, Irene; Luceron-Lucas-Torres, Maribel; Rodríguez-Gutiérrez, Eva; Berlanga-Macias, Carlos; Fernández-Bravo-Rodrigo, Jaime; Patino-Cardona, Silvana (MDPI, 2025-05-10)
    Background/Objectives: Dietary advanced glycation end products (dAGEs) have a pro-inflammatory effect and increase oxidative stress, potentially leading to cancer. The aim of this study was to estimate the association ...
  • Understanding the Natural History and the Effects of Current Therapeutic Strategies on Urea Cycle Disorders: Insights from the UCD Spanish Registry 
    Martín-Hernández, Elena; Bellusci, Marcello; Pérez-Mohand, Patricia; Correcher-Medina, Patricia; Blasco-Alonso, Javier; Morais-López, Ana; de-las-Heras, Javier; Meavilla-Olivas, Silvia-María; Dougherty-de-Miguel, Lucy; Couce, María-Luz; Canedo-Villarroya, Elvira; García-Jiménez, María-Concepción; Moreno-Lozano, Pedro-Juan; Vives-Piñera, Inmaculada; Gil-Campos, Mercedes; Stanescu, Sinziana; Ceberio-Hualde, Leticia; Camprodon, María; Cortés-Saladelafont, Elisenda; López-Urdiales, Rafael; Murray-Hurtado, Mercedes; Márquez-Armenteros, Ana-María; Sierra-Córcoles, Concha; Peña-Quintana, Luis; Ruiz-Pons, Mónica; Alcalde, Carlos; Castellanos-Pinedo, Fernando; Dios, Elena; Barrio-Carreras, Delia; Martín-Cazana, María; García-Peris, Mónica; Andrade, José-David; García-Volpe, Camila; de-los-Santos, Mariela; García-Cazorla, Angels; del-Toro, Mireia; Felipe-Rucian, Ana; Comino-Monroy, María-José; Sánchez-Pintos, Paula; Matas, Ana; Gil-Ortega, David; Martín-Rivada, Álvaro; Bergua, Ana; Belanger-Quintana, Amaya; Vitoria, Isidro; Yahyaoui, Raquel; Pérez, Belén; Morales-Conejo, Montserrat; Quijada-Fraile, Pilar (MDPI, 2025-03-28)
    Background/Objectives: The present study updates the Spanish registry of patients with urea cycle disorders (UCD), originally established in 2013, to provide comprehensive epidemiological data and evaluate the impact of ...
  • Diet, Advanced Maternal Age, and Neonatal Outcomes: Results from the GESTAGE Study 
    Puche-Juarez, María; Toledano, Juan-M; Hinojosa-Nogueira, Daniel; de-Paco-Matallana, Catalina; Sánchez-Romero, Javier; Ochoa, Julio-J; Carrillo, María-Paz; Martín-Álvarez, Estefanía; Díaz-Castro, Javier; Moreno-Fernández, Jorge (MDPI, 2025-01-17)
    Maternal nutrition during pregnancy plays a pivotal role in influencing both maternal and fetal health, impacting neonatal anthropometric outcomes and long-term disease susceptibility. An advanced maternal age (AMA ? 35 ...
  • Graphene-Based Materials for Bone Regeneration in Dentistry: A Systematic Review of In Vitro Applications and Material Comparisons 
    Narváez-Romero, Azahara-María; Rodríguez-Lozano, Francisco-Javier; Pecci-Lloret, María-Pilar (MDPI, 2025-01-08)
    INTRODUCTION: Graphene, a two-dimensional arrangement of carbon atoms, has drawn significant interest in medical research due to its unique properties. In the context of bone regeneration, graphene has shown several promising ...