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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Effect of a competence based medical education program on training quality in Intensive Care Medicine. COBALIDATION TRIAL. 
    Castellanos-Ortega, Álvaro; Broch-Porcar, María-Jesús; Palacios-Castañeda, Diego; Gómez-Tello, Vicente; Valdivia, Miguel; Vicent, Carlos; Madrid, Isabel; Martínez, Nuria; Párraga-Ramírez, Manuel-José; Sancho, Elena; del-Castillo-Fuentes-Dura, María; García-Ros, Rafael (ELSEVIER, 2025-06)
    OBJECTIVES: The main objective of this study was to evaluate whether the implementation of CoBaTrICE (Competency-Based Training in Intensive Care Medicine in Europe) provides higher levels of competency in comparison with ...
  • Effectiveness of catch-up and at-birth nirsevimab immunisation against RSV hospital admission in the first year of life: a population-based case-control study, Spain, 2023/24 season 
    Núñez, Olivier; Olmedo, Carmen; Moreno-Pérez, David; Lorusso, Nicola; Fernández-Martínez, Sergio; Pastor-Villalba, Pedro-Eliseo; Gutiérrez, Ángeles; García, Marcos-Alonso; Latasa, Pello; Sancho, Rosa; Mendioroz, Jacobo; Martínez-Marcos, Montserrat; Muñoz-Platon, Enrique; García-Rivera, María-Victoria; Pérez-Martínez, Olaia; Álvarez-Gil, Rosa; Wagner, Eva-Rivas; López-González-Coviella, Nieves; Zornoza-Moreno, Matilde; Barranco-Boada, María-Isabel; Pacheco, M-del-Carmen; Álvarez-Río, Virginia; Jaume, Miguel-Fiol; Arance, Roxana-Morey; Sancho, Begoña-Adiego; Méndez-Díaz, Manuel; Batalla-Rebollo, Noa; Andreu, Cristina; Castilla, Jesús; García-Cenoz, Manuel; Fernández-Ibáñez, Ana; Huerta-Huerta, Marta; Ibáñez-Pérez, Ana-Carmen; Berradre-Saenz, Belén; Lamas, Joaquín; Hermoso, Luisa; Casado-Cobo, Susana; Galán-Cuesta, Manuel; Montenegro, Sara; Domínguez, María; Jarrin, Inmaculada; Limia, Aurora; Pastor-Barriuso, Roberto; Monge, Susana (EUR CENTRE DIS PREVENTION & CONTROL, 2025-02-06)
    BackgroundRespiratory syncytial virus (RSV) causes substantial morbidity in infants < 1 year. In October 2023, Spain recommended the monoclonal antibody nirsevimab to all children born since 1 April 2023, at birth or as ...
  • Breastmilk polyamines modify gut gene expression in children at three months of age 
    Sánchez-Campillo, María; Gázquez, Antonio; Pastor-Fajardo, María-Teresa; López-Andreo, María-J; Pérez-Andres, Adrián; Martínez-Graciá, Carmen; Vioque, Jesús; Pérez-Fernández, Virginia; García-Marcos, Luis; Larque, Elvira (CHURCHILL LIVINGSTONE, 2025-03)
    BACKGROUND & AIMS: Breastmilk is one of the main sources of exogenous polyamines for newborns and contains higher polyamine content than infant formulas. Polyamines are involved in gut maturation and immune system regulation ...
  • Naxos Disease and Related Cardio-Cutaneous Syndromes 
    Protonotarios, Alexandros; Asimaki, Angeliki; Basso, Cristina; Xylouri, Zafeirenia; Monda, Emanuele; Protonotarios, Ioannis; Crisci, Giulia; Abrahms, Dominic-JR; Anastasakis, Aris; Antoniades, Loizos; Bakalakos, Athanasios; Carbone, Andreina; Coonar, Aman-S; Gimeno-Blanes, Juan-Ramón; Lazaros, George; Lerakis, Stamatios; Mestroni, Luisa; Papadopoulos, George; Pecchia, Leandro; Prandi, Francesca-Romana; Syrris, Petros; Cadrin-Turigny, Julia; Vasilakis, Anargyros; Saffitz, Jeffrey-E; Thiene, Gaetano; Elliott, Perry-M; Kaski, Juan-Pablo; Mckenna, William-J; Bossone, Eduardo; Limongelli, Giuseppe; Tsatsopoulou, Adalena (ELSEVIER, 2025-02)
    Naxos disease is a rare autosomal recessive condition combining arrhythmogenic right ventricular cardiomyopathy, woolly hair, and palmoplantar keratoderma. The first identified causative variant was in the gene encoding ...
  • The impact of blood eosinophil count and FeNO on benralizumab effectiveness in clinical practice: An ORBE II subanalysis 
    García-Moguel, Ismael; Martínez-Mesa, Álvaro; Andújar-Espinosa, Rubén; Díaz-Campos, Rocío; Velasco-Garrido, José-Luis; Sánchez-Trincado, José-Luis; Luzon, Elisa; Nuevo, Javier; Alconada, Carlos; Gutiérrez, Miguel-Ángel; Niza, Gabriel; Padilla-Galo, Alicia (W B SAUNDERS CO LTD, 2025-02)
    BACKGROUND: The ORBE II study showed the real-world effectiveness of benralizumab in severe eosinophilic asthma (SEA). This subgroup analysis aimed to characterize patients and outcomes based on baseline blood eosinophil ...
  • Genetic association between sleep quality, insomnia, and psychological distress: a systematic review and meta-analysis 
    Blanco-García, Federico-J; López-López, José-Antonio; Ordoñana, Juan-Ramón; Madrid-Valero, Juan-José (W B SAUNDERS CO LTD, 2025-10)
    There is a well-established link between sleep disorders and psychological problems such as anxiety and depression. Twin studies and genome-wide association studies (GWAS) have consistently found significant genetic overlap ...
  • Variation in Venous Thromboembolism Outcomes Based on Primary Cancer Site A RIETE Registry Analysis 
    Trujillo-Santos, Javier; Ay, Cihan; Bikdeli, Behnood; Jimenez, David; Villalobos, Aurora; Lopez-Jimenez, Luciano; Perez-Pinar, Montserrat; Pagan-Escribano, Javier; Ciammaichella, Maurizio; Monreal, Manuel (ELSEVIER, 2025-09)
    BACKGROUND: Patients with cancer-associated venous thromboembolism (VTE) are at increased risk of both recurrent VTE and bleeding. These risks may vary by cancer site, but the magnitude of this variation remains unclear. ...
  • Lipidomics Unveils Critical Lipid Pathway Shifts in Alport Syndrome 
    Requena, Belen; Shabaka, Amir; Lanzon, Borja; Martinez, Sara; Carrillo, Isabel Galan; Bada-Bosch, Teresa; Sevillano, Angel; Tato-Ribera, Ana Maria; Barbas, Coral; Medina-Gomez, Gema; Gonzalez-Riano, Carolina; Fernandez-Juarez, Gema (ELSEVIER SCIENCE INC, 2025-08)
    INTRODUCTION: Alport syndrome (AS) is a hereditary kidney disease from COL4A3-5 pathogenic variants causing glomerular basement membrane abnormalities. Although genetic and structural aspects are known, mechanisms linking ...
  • Identifying Predictors for Heart Failure Outcomes in Phospholamban p.(Arg14del)-Positive Individuals 
    van-der-Heide, Myrthe-Y-C; Verstraelen, Tom-E; de-Brouwer, Remco; van-Drie, Esmee; Proost, Virginnio-M; van-Lint, Freyja-H-M; Bosman, Laurens-P; Houweling, Arjan-C; Dickhoff, Cathelijne; Germans, Tjeerd; Schoonderwoerd, Bas-A; Gimeno-Blanes, Juan-Ramón; Meems, Laura-M-G; te-Riele, Anneline-S-J-M; van-Spaendonck-Zwarts, Karin-Y; Cox, Moniek-G-P-J; Amin, Ahmad-S; van-Tintelen, J-Peter; de-Boer, Rudolf-A; Zwinderman, Aeilko-H; Wilde, Arthur-A-M (ELSEVIER SCI LTD, 2025-10)
    BACKGROUND: Phospholamban (PLN) p.(Arg14del)-positive individuals are at high risk of developing PLN p.(Arg14del)-related cardiomyopathy, which can lead to progressive heart failure that is poorly amenable to standard heart ...
  • Concentration-dependent biphasic toxicity and steroidogenic stimulation by aminocarb in murine Leydig cells 
    Moreira, Silvia; Martins, Ana-D; Bernardino, Raquel-L; Pinho, Marisa; Guerra, Inés-M-S; Alves, Marco-G; Pastor, Luis-Miguel; Seco-Rovira, Vicente; Pereira, María-de-Lourdes; Oliveira, Pedro-F; Domingues, M-Rosario (ELSEVIER, 2025-09)
    Exposure to environmental chemicals, like pesticides, can impair male reproductive health by affecting Leydig cell (LC) function. This study investigated aminocarb, a widely used carbamate pesticide, and its impact on ...
  • Long-term outcomes of hydrodynamic ultra-thin strut sirolimus-eluting stent with fluoropolymer containing triflusal: VELAZQUEZ-EPIC26 study. 
    Linares-Vicente, José-Antonio; Sainz-Laso, Fermin; Casanova-Sandoval, Juan-Manuel; Rumoroso-Cueva, José-Ramón; Gómez-Menchero, Antonio; Gómez-Hospital, Joan-Antoni; Pérez-Guerrero, Ainhoa; Santos-Martínez, Sandra; Fernández-Portales, Javier; Romani, Sebastian; García-del-Blanco, Bruno; Ocaranza-Sánchez, Raymundo; Urbano-Carrillo, Cristóbal; García-San-Roman, Koldobika; Vinhas, Hugo; Cid-Álvarez, Belén; Sanchis-Fores, Juan; Telleria-Arrieta, Miren; Torres-Bosco, Alfonso; Pinar-Bermúdez, Eduardo; Méndez-Castro, José-Juan; Lozano-Ruiz-de-Poveda, Fernando; Pérez-de-Prado, Armando; De-la-Torre-Hernández, José-María (ELSEVIER, 2025-07)
    BACKGROUND: A new-generation coronary sirolimus eluting-stent(SES), whose novel characteristics are summarized in ultra-thin oval-shaped hydrodynamic struts (68 ?m) and abluminal drug release with permanent fluoropolymer ...
  • Efficacy and safety of efavirenz in Niemann-Pick disease type C 
    Gascon-Bayarri, Jordi; Rico, Inmaculada; Sanchez-Castaneda, Cristina; Ledesma, Maria Dolores; Carnaval, Thiago; Bejr-Kasem, Helena; Campdelacreu, Jaume; Ferrer, Anna; Rodriguez-Bel, Laura; Cos, Monica; de Lama, Eugenia; de Munain, Adolfo Lopez; Rouco, Idoia; Perez-Sousa, Celia; Cerdan, Maria; Muelas, Nuria; Sevillano, Maria Dolores; Mir, Pablo; Villoria, Jesus; Videla, Sebastian (ELSEVIER SCIENCE INC, 2025-09)
    INTRODUCTION: In search of disease-modifying treatments for the Niemann-Pick disease type C (NPC), this Phase II single-arm clinical trial evaluated the safety and efficacy of efavirenz, a reverse transcriptase inhibitor ...
  • Sharp increase in the incidence and severity of invasive Streptococcus pyogenes infections in children after the COVID-19 pandemic (2019-2023): A nationwide multicenter study 
    Cobo-Vázquez, Elvira; Aguilera-Alonso, David; Grandioso-Vas, David; Gamell, Anna; Rello-Saltor, Victoria; Oltra-Benavent, Manuel; Cervantes-Hernández, Eloisa; Sanz-Santaeufemia, Francisco; Carrasco-Colom, Jaime; Manzanares-Casteleiro, Ángela; Martín-Pedraz, Laura; Ramírez-de-Arellano, Eva; Falcon-Neira, Lola; Martínez-Campos, Leticia; Colino-Gil, Elena; Jiménez-Montero, Beatriz; Calavia, Olga; Hernández-Ventura, Anna; Del-Castillo-Navio, Elena; Matias-del-Pozo, Vanesa; Calle-Miguel, Laura; Soto, Beatriz; Fernández, Berta; Camil-Olteanu, Filip; Pareja-León, Marta; López-Segura, Nuria; Ara-Montojo, Fátima; Ruiz-Sáez, Beatriz; Calvo-Monge, Cristina; Sánchez-Codez, María; Reinoso, Teresa; Badillo, Katie; Vázquez, Carmen; Villalon, Pilar; Oteo-Iglesias, Jesús; Mellado-Sola, Isabel; Cercenado, Emilia; Blázquez-Gamero, Daniel; Menasalvas-Ruiz, Ana-Isabel; González-Abad, María-José; Guarch, Borja; Ibáñez-Alcalde, Mercedes; Carazo, Begoña; Lung, Mayli; Calvo, Cristina; Saavedra-Lozano, Jesús (ELSEVIER SCI LTD, 2025-10)
    OBJECTIVES: A global surge in pediatric invasive group A streptococcal infection (iGAS) was reported after autumn 2022. This study analyzed the epidemiology and severity of iGAS in Spain, comparing two periods; P1: ...
  • Severe Neutropenia in Infants With Congenital Cytomegalovirus on Antiviral Therapy 
    Papaevangelou, Vassiliki; Pedrero-Tome, Roberto; Syridou, Garyfallia; Baquero-Artigao, Fernando; Rodriguez-Molino, Paula; del Rosal, Teresa; Noguera-Julian, Antoni; Rios-Barnes, Maria; Fortuny, Claudia; Villaverde, Serena; Frick, Maria Antoinnette; Vallejo, Beatriz Alvarez; Soler-Palacin, Pere; Saavedra, Jesus; Karagiannidou, Sofia; Rincon, Elena; Busselo, Itziar Sota; Zuriarrain, Oihana Muga; Calderon, Elisenda Moliner; Tagarro, Alfredo; Malumbres, Maria; Colino, Elena; Llanos, Elisa Garrote; Ruiz, Ana Menasalvas; Mateos, Miguel Sanchez; Espuny, Xavier Bringue; Alonso-Ojembarrena, Almudena; Ferreras-Antolin, Laura; Perez, Irene Cuadrado; Posse, Ana Filgueira; Lyall, Hermione; Blazquez-Gamero, Daniel (LIPPINCOTT WILLIAMS & WILKINS, 2025-11)
    AIM: To describe European real-life experience of severe neutropenia (SN) during ganciclovir (GCV) and/or valganciclovir (VGCV) treatment in infants with congenital cytomegalovirus (cCMV) infection and identify risk factors ...
  • Impact of a community-based educational intervention on the burden and health-related quality of life of informal caregivers 
    Martínez-Melero, Inmaculada; Ruiz-García, María-Jesús; Ruiz-Merino, Guadalupe; García-Rubio, Ana (MOSBY-ELSEVIER, 2025-09)
    BACKGROUND: Caregiving for immobilized patients presents significant challenges that can profoundly impact the mental and physical health of informal caregivers. This study evaluates the impact of a community-based educational ...
  • Sex Differences in Children and Adolescents With Hypertrophic Cardiomyopathy 
    Norrish, Gabrielle; Hall, Kimberley; Field, Ella; Cervi, Elena; Boleti, Olga; Ziolkowska, Lidia; Olivotto, Iacopo; Passantino, Sylvia; Khraiche, Diala; Limongelli, Giuseppe; Weintraub, Robert-G; Anastasakis, Aris; Biagini, Elena; Ragni, Luca; Sarquella-Brugada, Georgia; Cesar, Sergi; Prendiville, Terrence; McLeod, Karen; Ilina, María; Baban, Anwar; Ojala, Tiina-H; Spentzou, Georgia; Bhole, Vinay; Gran, Feran; Brown, Elspeth; Delle-Donne, Grazia; Khodaghalian, Bernadette; Fernández, Adrián; Daubeney, Piers-E-F; Linter, Katie; Kubus, Peter; Uzun, Orhan; Bokenkamp, Regina; Raimondi, Francesca; Marrone, Chiara; Medrano, Constantio; González-López, Esther; Siles, Ana; Luczak-Wozniak, Katarzyna; Bharucha, Tara; Adwani, Satish; Klaassen, Sabine; Castro, Fernando-J; Guereta, Luis; Yamazawa, Hirokuni; Sinagra, Gianfranco; Popoiu, Anca; Perin, Francesca; Chana, B; De-Wilde, Hans; Rasmussen, Torsten-B; Mogensen, Jens; Mathur, Sujeev; Centeno, Fernando; Reinhardt, Zdenka; Barriales-Villa, Roberto; Kubo, Toru; Felice, Tiziana; Radulescu, Cristina; Schouvey, Sylvie; Chaker, Melissa; Kaski, Juan-Pablo (ELSEVIER, 2025-08)
    BACKGROUND: Sex differences have been described in adults with hypertrophic cardiomyopathy (HCM), but it is unknown if similar differences exist in childhood-onset disease. OBJECTIVES: This study aimed to investigate the ...
  • Comparative analysis of cryoballoon versus radiofrequency catheter ablation in atrial fibrillation patients with impaired left ventricular ejection fraction 
    Pongratz, J; Kuck, K-h; Metznerc, A; Hink, U; García-Alberola, Arcadio; Borchard, R; Noelker, G; Kuniss, M; Tilz, R-R; Schrickeli, J-W; Thornton, A; Thomas, D; Katus, H-A; Zahn, R; Spitzer, S; Souza, J-J; Brachmann, J; Tebbenjohanns, J; Wu, L-q; Obel, W-P; Groschup, G; Stellbrink, C; Chun, K-R-J; Gerds-Li, J-h; Stanley, A; Gopal, R-R; Lickfett, L; Lubinski, A; Schumacher, B; Steinwender, C; Franke, H-A; Ouarrak, T; Dorwarth, U; Senges, J; Hoffmann, E; Straube, F (ELSEVIER IRELAND LTD, 2025-08)
    BACKGROUND: In selected patients with atrial fibrillation (AF) and impaired left ventricular ejection fraction (LVEF), catheter ablation has been proposed for rhythm control. It is unclear, if cryoballoon (CBA) or ...
  • Lower rate of pancreatobiliary complications after sludge and microlithiasis pancreatitis compared to gallstone pancreatitis 
    Sirtl, Simon; Teodorescu, Bianca; Gilberg, Leónard; Schafer, Arlett; Beyer, Georg; Arnau, Anna; López-Guillén, Pablo; Martínez-Domínguez, Samuel-J; Abad-Baroja, Daniel; Oyon, Daniel; Ruiz-Belmonte, Lara-M; Tejedor-Tejada, Javier; Zapater, Raúl; Martín-Vicente, Noelia; Fernández-Esparcia, Pedro-José; Julián-Gomara, Ana-Belén; Sastre-Lozano, Violeta-María; Manzanares-García, Juan-José; Chivato-Martín-Falquina, Irene; Andrés-Pascual, Laura; Torres-Monclús, Nuria; Zaragoza-Velasco, Natividad; Rojo, Eukene; Lapena-Muñoz, Berta; Flores, Virginia; Díaz-Gómez, Arantxa; Canamares-Orbis, Pablo; Vinzo-Abizanda, Isabel; Carrasco, Natalia-Marcos; Pardo-Grau, Laura; García-Rayado, Guillermo; Millastre-Bocos, Judith; García-García-de-Paredes, Ana; Vaamonde-Lorenzo, María; Izaguirre-Arostegi, Arantzazu; Lozada-Hernández, Edgard-Efren; Velarde-Ruiz-Velasco, José-Antonio; Zorniak, Michal; de-Madaria, Enrique; Mayerle, Julia; Velamazan, Raúl (ELSEVIER SCIENCE INC, 2025-09)
    BACKGROUND AND AIMS: Cholecystectomy is recommended to prevent recurrence of biliary pancreatitis, but supporting evidence is limited for sludge- and microlithiasis-induced acute pancreatitis (AP). This study aimed to ...
  • MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer 
    del Rey-Vergara, Raul; Galindo-Campos, Miguel Alejandro; Rocha, Pedro; Carpes, Marina; Martinez, Carlos; Masfarre, Laura; Menendez, Silvia; Quimis, Fabricio; Rossell, Adria; Inanez, Albert; Perez-Buira, Sandra; Rojo, Federico; Gimeno, Ramon; Isla, Dolores; Zugazagoitia, Jon; Blanco, Cristina Marti; Garcia-Campelo, Rosario; Moreno-Vega, Alberto; Leon-Mateos, Luis; Mellen, Angel Callejo; Park, Kwon-Sik; Heeke, Simon; Heymach, John V.; Taus, Alvaro; Paz-Ares, Luis; Rovira, Ana; Arriola, Edurne (CELL PRESS, 2025-07)
    The introduction of immunotherapy as a first-line treatment for advanced small cell lung cancer (SCLC) represents significant progress, yet there remains an opportunity to further improve patient outcomes. Hepatocyte growth ...
  • Practical guideline for major hereditary thrombophilia 
    Tang, Liang, V; Morange, Pierre-Emmanuel; Corral, Javier; Ntaios, Georgios; Spyropoulos, Alex C.; Lip, Gregory Y. H.; Douketis, James D. (CELL PRESS, 2025-06)