Repositorio Dspace

Envíos recientes

Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Effect of beta blockers in acute and chronic coronary syndromes without reduced ejection fraction: a landmark analysis from the REBOOT trial. 
    Rossello, Xavier; Barrabes, José-A; Piepoli, Massimo; Dominguez-Rodríguez, Alberto; Sánchez, Pedro-L; Anguita, Manuel; Raposeiras-Roubin, Sergio; Grigis, Giulietta; Aguero, Jaume; Owen, Ruth; Pocock, Stuart; Pérez-García, Carlos-Nicolás; Escalera, Noemi; Kallmeyer, Andrea; Sionis, Alessandro; Staszewsky, Lidia; Torres, Alfonso; Barquero, Rocio; Fernández-Vazquez, Felipe; Marín-Ortuño, Francisco; Vetrano, Alfredo; Pastor, Pablo; Fuster, Valentín; Latini, Roberto; Ibañez, Borja (2026-01-22)
    BACKGROUND AND AIMS: Current guidelines recommend beta-blocker therapy after myocardial infarction (MI) regardless of left ventricular ejection fraction (LVEF). However, recent trials question their benefit in patients ...
  • Walking promotion in healthy pregnant women and perinatal outcomes: a multivariate analysis comparing active and sedentary mothers 
    Benito-Villena, Rebeca; Cano-Ibáñez, Naomi; Gallardo-Vera, Andrea; Mozas-Moreno, Juan; Khan, Khalid-Saeed; Puertas-Prieto, Alberto; Amezcua-Prieto, Carmen (2026-12-31)
    BACKGROUND: Regular physical activity during pregnancy is associated with important maternal health benefits, yet the specific impact of walking on labour and neonatal outcomes remains unclear. Although walking is the most ...
  • Precision health targeting TMAO in postmenopausal women: polyphenol effects modulated by urolithin A and equol metabotypes in a randomised, placebo-controlled crossover trial 
    Jarrin-Orozco, María-Paula; García-Nicolás, María; Romo-Vaquero, María; Carrascosa-Romero, María Concepción; Berna, José; Puigcerver, Julio; Saura-Sanmartín, Adrián; Avila-Galvez, María-Ángeles; Espín, Juan-Carlos (ROYAL SOC CHEMISTRY, 2026)
    Menopause increases cardiometabolic risk, partly by reducing the protective effects of estrogens and inducing gut microbiota dysbiosis, which can promote the production of atherogenic metabolites such as trimethylamine ...
  • Metabolomic profiling of urinary phenolic compounds in postmenopausal women after consumption of dark chocolate, green tea, and fruit juice 
    Sánchez-Martínez, Lorena; Tosi, Nicole; Bragazzi, Nicola-Luigi; Bresciani, Letizia; del-Rio, Daniele; Periago, María-Jesús; Mena, Pedro; González-Barrio, Rocío (ROYAL SOC CHEMISTRY, 2026)
    Postmenopausal women are approximately twice as likely to develop cardiometabolic diseases (CMDs) as premenopausal women. Plant-based diets rich in fruits and vegetables, due to their high content of bioactive compounds ...
  • TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome 
    Lozano-Gil, Juan-Manuel; Rodríguez-Ruiz, Lola; Palacios, Manuel; Peral, Jorge; Navarro, Susana; Fuster-Soler, José-Luis; Beléndez, Cristina; Jérez-Cayuela, Andrés; Murillo-Sanjuan, Laura; Díaz-de-Heredia, Cristina; López-de-Hontanar, Guzmán; Zubicaray, Josune; Sevilla, Julián; Ferrer-Marín, Francisca; Sepulcre-Cortés, María-Pilar; Cayuela-Fuentes, María-Luisa; García-Moreno, Diana; Martínez-López, Alicia; Tyrkalska, Sylwia-D; Mulero, Victoriano (SPRINGERNATURE, 2026-01-09)
    Diamond-Blackfan anemia syndrome (DBAS) is marked by defective erythropoiesis caused by impaired ribosome biogenesis and aberrant signaling. Here, we investigate how ribosomal stress-induced activation of the NLRP1 ...
  • Expanding the genetic landscape of inherited metabolic diseases using long-read sequencing and transcriptomic profiling 
    Soriano-Sexto, Alejandro; Sánchez-Lijarcio, Obdulia; Beccari, Leonardo; Castejón-Fernández, Natalia; Leal, Fátima; Alcaide, Patricia; de-la-Morena-Barrio, Belén; Bahillo-Curieses, María-del-Pilar; Correcher, Patricia; Hencke-Tresbach, Rafael; López, Laura; Martín-Hernández, Elena; Yahyaoui, Raquel; Ugarte, Magdalena; Rodríguez-Pombo, Pilar; Pérez, Belén (SPRINGERNATURE, 2026-01-26)
    Although next-generation sequencing has emerged as a powerful tool for diagnosing rare diseases (RD), many cases of inherited metabolic diseases (IMD) remain unsolved, hindering the diagnosis, clinical and therapeutic ...
  • Contrast-enhanced CT in sepsis: insights from a European Emergency Radiology survey 
    Stahl, Ann-Christine; Rubarth, Kerstin; Opper-Hernando, María-Isabel; Frisch, Anne; Blanco-Barrio, Ana; Basilico, Raffaella; Miele, Vittorio; Iacobellis, Francesca; Bolanaki, Myrto; Witham, Denis; Dewey, Marc; Pohlan, Julián (SPRINGERNATURE, 2026-01-26)
    Objectives To gain insight into emergency radiologists' views on the role of contrast-enhanced CT (CECT) in sepsis management. Materials and methods This analysis of a survey distributed in 2023 to members of the European ...
  • One-year consolidation with Ponatinib 15 mg in chronic myeloid leukaemia on deep molecular response with Imatinib 
    Pérez-Lamas, Lucía; Manzanares, Mario; Hernández-Boluda, Juan-Carlos; Casado-Montero, Luis-Felipe; Gómez-Casares, María-Teresa; Ayala, Rosa; Xicoy, Blanca; Ferrer-Marín, Francisca; Orti, Guillermo; De-Paz-Arias, Raquel; Osorio-Prendes, Santiago; Pérez-López, Raúl; Mora, Elvira; Ruiz-Nuno, Concepción; Jiménez-Velasco, Antonio; Boque, Concepción; Sierra-Pacho, Magdalena; Martínez-López, Joaquín; Carreño-Tarragona, Gonzalo; Coiras, Mayte; García-Gutiérrez, Valentín (SPRINGERNATURE, 2026-01-20)
    Tyrosine kinase inhibitors (TKIs) discontinuation is the standard option for patients with chronic myeloid leukaemia (CML) in deep molecular response (MR) with imatinib. This study aimed to evaluate the efficacy and safety ...
  • Anesthesia Modality in Intracranial Stenting for Acute Stroke-A Sub-Analysis of the RESISTANT International Registry 
    Sousa, Joao-Andre; Olive-Gadea, Marta; Diana, Francesco; Kaesmacher, Johannes; Mujanovic, Adnan; Geyik, Serdar; Senadim, Songul; Cervo, Amedeo; Salcuni, Andrea; Piano, Mari-Ángela; Moreu, Manuel; López-Frias, Alfonso; Hassan, Ameer; Miller, Samantha; Zapata-Arriaza, Elena; De-Alboniga-Chindurza, Asier; Bergui, Mauro; Molinaro, Stefano; Gomes, Fabio; Sargento-Freitas, Joao; Alexandre, Andrea; Pedicelli, Alessandro; Hofmeister, Jeremy; Machi, Paolo; Scarcia, Luca; Kalsoum, Erwah; Amorim, José; Meira, Torcato; Ortega-Gutiérrez, Santiago; Rodríguez-Calienes, Aarón; Renieri, Leonardo; Capasso, Francesco; Románo, Daniele; Bárcena-Ruiz, Eduardo; Seoane, David; Abdalkader, Mohamad; Klein, Piers; N-Nguyen, Thanh; Perry, Catarina; Fragata, Isabel; Yavagal, Dileep; Charles, Jude; Rodríguez-Castro, José; Vega, Pedro; Ozcan-Ozdemir, Atilla; Uysal-Kocabas, Zehra; Smajda, Stanislas; Al-Salman, Sadiq; Khalife, Jane; Jovin, Tudor; Biraschi, Francesco; Ricchetti, Francesca; Castro, Pedro; Albuquerque, Luis; Siddiqui, Adnan; Jaikumar, Vinay; Navia, Pedro; Ntoulias, Nikos; Psychogios, MaRíos; Velo, Mariano; Zamarro, Joaquín; De-Paco, Gonzalo; Ashouri, Yazan; Almajali, Mohammad; Arenillas, Juan-F; Sierra, Alicia; Romoli, Michele; Marto, Joao-Pedro; Yaghi, Shadi; Ribo, Marc; Tomásello, Alejandro; Requena, Manuel (SPRINGERNATURE, 2026-02-03)
    PurposeThe optimal anesthetic approach for intracranial stenting in acute stroke remains unclear. We compared outcomes of patients under general anesthesia (GA) versus local anesthesia or conscious sedation.MethodsThe ...
  • Roots of resilience: Assessing child and adolescent nature connectivity in the Mediterranean Region of Murcia (Spain) 
    Ortega-García, Juan-Antonio; Díaz-Martínez, Francisco; Cabrera-Rivera, Laura-Teresa; Cánovas-Conesa, Carmen-Alicia; Codina, Elena; Ramis, Rebeca; Claudio, Luz (WILEY, 2026-02)
    <p style="border:0px; display:block; height:0px; left:-9999px; margin-bottom:0px; margin-left:0px; margin-right:0px; margin-top:0px; opacity:0; overflow:hidden; padding:0px; position:absolute; top:0px; width:0px"> Children ...
  • Differences in circadian sleep parameters as a function of gender in patients on the waiting list for liver transplantation. 
    Martínez-Alarcon, Laura; Jover-Águilar, Marta; Sáez-Sánchez, Javier; Ramírez, Pablo; Ramis-Vidal, Guillermo (ELSEVIER, 2026-02)
    Sleep is a critical component of health, yet its role is underexplored in patients awaiting organ transplantation. This study examined sex-based differences in circadian sleep indicators among liver transplant candidates. ...
  • Integrated care for COPD and cardiovascular comorbidities: A multidisciplinary approach for the cardiopulmonary patient 
    De-Simón-Gutiérrez, R; Alcázar-Navarrete, B; Alonso-Ortiz, M-B; Delgado-Jiménez, J-F; Gómez-Doblas, J-J; Hurtado-García, R; López-Caro, J-C; Méndez-Bailón, M; Nuñez-Villota, J; Piñera-Salmerón, Pascual; Herrero, Pulido; Rey-Aldana, D; Soler-Cataluna, J-J; Trigueros-Carrero, J-A; Zamorano-Serrano, M-J; De-Miguel-Díez, J (ELSEVIER, 2026-03)
    Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) frequently coexist, each increasing the prevalence of the other and worsening their clinical manifestations and prognosis. The common ...
  • Disease activity and hyperuricemia predict the development of cardiovascular events in patients with Psoriatic Arthritis: results of the 10-year prospective evaluation in the CARMA cohort 
    Llorca, Javier; Ferraz-Amaro, Iván; Moreno-Martínez, María-José; Plaza, Zulema; Sánchez-Alonso, Fernando; Moreno-Ramos, Manuel-José; García-Gómez, Carmen; Castaneda, Santos; González-Juanatey, Carlos; González-Gay, Miguel-Ángel (ELSEVIER, 2026-04)
    Objective: To identify predictors of cardiovascular (CV) events in psoriatic arthritis (PsA) patients from the CARdiovascular in RheuMAtology (CARMA) project during 10 years of prospective follow-up. Methods: Between July ...
  • Spanish multidisciplinary consensus on the diagnosis and management of laryngopharyngeal reflux (ReFaL Consensus) 
    Sevilla-García, María-Agustina; Chiesa-Estomba, Carlos-Miguel; Barona-Lleó, Luz; Álvarez-Sánchez, Ángel; Martín-de-Argila, Carlos (ELSEVIER, 2026-01)
    Introduction: Laryngopharyngeal reflux (LPR) represents a diagnostic and therapeutic challenge due to the nonspecific nature of its clinical manifestations and the absence of objective biomarkers. The aim of this work is ...
  • Healthcare resource utilization and costs of chronic kidney disease in Spain across KDIGO categories: Insights from real-world evidence 
    Santamaría, Rafael; Escobar, Carlos; Aranda, Unai; Palacios, Beatriz; Capel, Margarita; Hernández, Ignacio; Cebrián-Cuenca, Ana-María; Alcázar, Roberto; Gorostidi, Manuel (ELSEVIER, 2026-01)
    Aim: To determine the healthcare resource utilization and costs in patients with chronic kidney disease (CKD) across the KDIGO stages in real-world clinical practice in Spain. Methods: Observational, retrospective study ...
  • Multicenter Prospective Study on Transvaginal Radiofrequency Ablation of Uterine Fibroids: Efficacy, Safety, and Reproducibility 
    Santalla-Hernández, Ángel; Gómez-Gutiérrez-Solana, Iván; De-la-Torre-Bulnes, María; Marín-Martínez, María-Eugenia; Molina-González, Domingo; Gadea-Niñoles, María-Esperanza; López-López, Antonia-María; Pelayo-Delgado, Irene; Torrijo-Rodrigo, Cristina; Lara-Peñaranda, Rosario; Palomo-Viciana, María-José; Naveiro-Fuentes, Mariña (ELSEVIER, 2026-01)
    OBJECTIVE: To evaluate the reproducibility, mid-term efficacy, and safety of transvaginal ultrasound-guided radiofrequency (RF) ablation of uterine fibroids among multiple centers and operators. DESIGN: Prospective multicenter ...
  • Chaperone-mediated autophagy sustains pericyte stemness necessary for brain tissue homeostasis 
    Salinas, María-Dolores; Martínez, Carlos-M; Roca, Francisco-J; García-Bernal, David; Martínez-Morga, Marta; Rodríguez-Madoz, Juan-R; Prosper, Felipe; Zapata, Agustin-G; Moraleda-Jiménez, José-María; Martínez, Salvador; Valdor-Alonso, Rut (ELSEVIER, 2026-02)
    Introduction: Pericytes (PCs) are mural cells exhibiting some mesenchymal stem cell (MSC) properties and contribute to tissue regeneration after injury. We have previously shown that glioblastoma cancer cells induce in ...
  • Intensification with a CCR5 inhibitor at antiretroviral therapy initiation modulates interleukin-18 and inflammation-driven immune pathways in people with HIV 
    De-la-Torre-Tarazona, Erick; Calderón-Vicente, Sergio; Fons-Contreras, María; Rava, Marta; Ruiz-Sancho, Andrés-Luis; Rivero, Antonio; Macías, Juan; Olalla, Julián; Alcaraz-Vidal, Begoña; Rodríguez-Díaz, Daniel; Alcami, José; Muriel, Alfonso; Serrano-Villar, Sergio; Moreno, Santiago (ELSEVIER, 2026-02)
    Objectives: Persistent inflammation in people with HIV (PWH) on antiretroviral therapy (ART) may drive comorbidities and disease progression. Because CCR5 signaling regulates viral entry and immune activation, maraviroc ...
  • Scoping review of the evolution of delirium detection, diagnostic, and severity assessment scales 
    Alonso-Crespo, David; Rodríguez-Mondéjar, Juan-José; Leal-Costa, César (ELSEVIER, 2026-04)
    Aim/Objective: To systematically compile and analyze all delirium detection tools, establishing a temporal and contextual framework to clarify current knowledge. Background: Delirium is a prevalent condition in hospitalized ...
  • Neuroimmune regulation of inflammation: RNA-Seq study of somatostatin-6 effects in gilthead seabream (Sparus aurata) skin and brain 
    Campos-Sánchez, José-Carlos; Espinosa-Ruiz, Cristobal; Marín-Parra, Claudia; Guardiola, Francisco-A; Rubio, Teresa; Pérez-Sanz, Fernando; Esteban, María-Ángeles (ELSEVIER, 2026-03)
    This study evaluated the anti-inflammatory potential of gilthead seabream somatostatin-6 (SST6) in a 2-carra-geenan-induced inflammation model using RNA-seq transcriptomics. We compared gene expression in the skin (primary ...