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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Naxos Disease and Related Cardio-Cutaneous Syndromes 
    Protonotarios, Alexandros; Asimaki, Angeliki; Basso, Cristina; Xylouri, Zafeirenia; Monda, Emanuele; Protonotarios, Ioannis; Crisci, Giulia; Abrahms, Dominic-JR; Anastasakis, Aris; Antoniades, Loizos; Bakalakos, Athanasios; Carbone, Andreina; Coonar, Aman-S; Gimeno-Blanes, Juan-Ramón; Lazaros, George; Lerakis, Stamatios; Mestroni, Luisa; Papadopoulos, George; Pecchia, Leandro; Prandi, Francesca-Romana; Syrris, Petros; Cadrin-Turigny, Julia; Vasilakis, Anargyros; Saffitz, Jeffrey-E; Thiene, Gaetano; Elliott, Perry-M; Kaski, Juan-Pablo; Mckenna, William-J; Bossone, Eduardo; Limongelli, Giuseppe; Tsatsopoulou, Adalena (ELSEVIER, 2025-02)
    Naxos disease is a rare autosomal recessive condition combining arrhythmogenic right ventricular cardiomyopathy, woolly hair, and palmoplantar keratoderma. The first identified causative variant was in the gene encoding ...
  • The impact of blood eosinophil count and FeNO on benralizumab effectiveness in clinical practice: An ORBE II subanalysis 
    García-Moguel, Ismael; Martínez-Mesa, Álvaro; Andújar-Espinosa, Rubén; Díaz-Campos, Rocío; Velasco-Garrido, José-Luis; Sánchez-Trincado, José-Luis; Luzon, Elisa; Nuevo, Javier; Alconada, Carlos; Gutiérrez, Miguel-Ángel; Niza, Gabriel; Padilla-Galo, Alicia (W B SAUNDERS CO LTD, 2025-02)
    BACKGROUND: The ORBE II study showed the real-world effectiveness of benralizumab in severe eosinophilic asthma (SEA). This subgroup analysis aimed to characterize patients and outcomes based on baseline blood eosinophil ...
  • Genetic association between sleep quality, insomnia, and psychological distress: a systematic review and meta-analysis 
    Blanco-García, Federico-J; López-López, José-Antonio; Ordoñana, Juan-Ramón; Madrid-Valero, Juan-José (W B SAUNDERS CO LTD, 2025-10)
    There is a well-established link between sleep disorders and psychological problems such as anxiety and depression. Twin studies and genome-wide association studies (GWAS) have consistently found significant genetic overlap ...
  • Variation in Venous Thromboembolism Outcomes Based on Primary Cancer Site A RIETE Registry Analysis 
    Trujillo-Santos, Javier; Ay, Cihan; Bikdeli, Behnood; Jimenez, David; Villalobos, Aurora; Lopez-Jimenez, Luciano; Perez-Pinar, Montserrat; Pagan-Escribano, Javier; Ciammaichella, Maurizio; Monreal, Manuel (ELSEVIER, 2025-09)
    BACKGROUND: Patients with cancer-associated venous thromboembolism (VTE) are at increased risk of both recurrent VTE and bleeding. These risks may vary by cancer site, but the magnitude of this variation remains unclear. ...
  • Lipidomics Unveils Critical Lipid Pathway Shifts in Alport Syndrome 
    Requena, Belen; Shabaka, Amir; Lanzon, Borja; Martinez, Sara; Carrillo, Isabel Galan; Bada-Bosch, Teresa; Sevillano, Angel; Tato-Ribera, Ana Maria; Barbas, Coral; Medina-Gomez, Gema; Gonzalez-Riano, Carolina; Fernandez-Juarez, Gema (ELSEVIER SCIENCE INC, 2025-08)
    INTRODUCTION: Alport syndrome (AS) is a hereditary kidney disease from COL4A3-5 pathogenic variants causing glomerular basement membrane abnormalities. Although genetic and structural aspects are known, mechanisms linking ...
  • Identifying Predictors for Heart Failure Outcomes in Phospholamban p.(Arg14del)-Positive Individuals 
    van-der-Heide, Myrthe-Y-C; Verstraelen, Tom-E; de-Brouwer, Remco; van-Drie, Esmee; Proost, Virginnio-M; van-Lint, Freyja-H-M; Bosman, Laurens-P; Houweling, Arjan-C; Dickhoff, Cathelijne; Germans, Tjeerd; Schoonderwoerd, Bas-A; Gimeno-Blanes, Juan-Ramón; Meems, Laura-M-G; te-Riele, Anneline-S-J-M; van-Spaendonck-Zwarts, Karin-Y; Cox, Moniek-G-P-J; Amin, Ahmad-S; van-Tintelen, J-Peter; de-Boer, Rudolf-A; Zwinderman, Aeilko-H; Wilde, Arthur-A-M (ELSEVIER SCI LTD, 2025-10)
    BACKGROUND: Phospholamban (PLN) p.(Arg14del)-positive individuals are at high risk of developing PLN p.(Arg14del)-related cardiomyopathy, which can lead to progressive heart failure that is poorly amenable to standard heart ...
  • Concentration-dependent biphasic toxicity and steroidogenic stimulation by aminocarb in murine Leydig cells 
    Moreira, Silvia; Martins, Ana-D; Bernardino, Raquel-L; Pinho, Marisa; Guerra, Inés-M-S; Alves, Marco-G; Pastor, Luis-Miguel; Seco-Rovira, Vicente; Pereira, María-de-Lourdes; Oliveira, Pedro-F; Domingues, M-Rosario (ELSEVIER, 2025-09)
    Exposure to environmental chemicals, like pesticides, can impair male reproductive health by affecting Leydig cell (LC) function. This study investigated aminocarb, a widely used carbamate pesticide, and its impact on ...
  • Long-term outcomes of hydrodynamic ultra-thin strut sirolimus-eluting stent with fluoropolymer containing triflusal: VELAZQUEZ-EPIC26 study. 
    Linares-Vicente, José-Antonio; Sainz-Laso, Fermin; Casanova-Sandoval, Juan-Manuel; Rumoroso-Cueva, José-Ramón; Gómez-Menchero, Antonio; Gómez-Hospital, Joan-Antoni; Pérez-Guerrero, Ainhoa; Santos-Martínez, Sandra; Fernández-Portales, Javier; Romani, Sebastian; García-del-Blanco, Bruno; Ocaranza-Sánchez, Raymundo; Urbano-Carrillo, Cristóbal; García-San-Roman, Koldobika; Vinhas, Hugo; Cid-Álvarez, Belén; Sanchis-Fores, Juan; Telleria-Arrieta, Miren; Torres-Bosco, Alfonso; Pinar-Bermúdez, Eduardo; Méndez-Castro, José-Juan; Lozano-Ruiz-de-Poveda, Fernando; Pérez-de-Prado, Armando; De-la-Torre-Hernández, José-María (ELSEVIER, 2025-07)
    BACKGROUND: A new-generation coronary sirolimus eluting-stent(SES), whose novel characteristics are summarized in ultra-thin oval-shaped hydrodynamic struts (68 ?m) and abluminal drug release with permanent fluoropolymer ...
  • Efficacy and safety of efavirenz in Niemann-Pick disease type C 
    Gascon-Bayarri, Jordi; Rico, Inmaculada; Sanchez-Castaneda, Cristina; Ledesma, Maria Dolores; Carnaval, Thiago; Bejr-Kasem, Helena; Campdelacreu, Jaume; Ferrer, Anna; Rodriguez-Bel, Laura; Cos, Monica; de Lama, Eugenia; de Munain, Adolfo Lopez; Rouco, Idoia; Perez-Sousa, Celia; Cerdan, Maria; Muelas, Nuria; Sevillano, Maria Dolores; Mir, Pablo; Villoria, Jesus; Videla, Sebastian (ELSEVIER SCIENCE INC, 2025-09)
    INTRODUCTION: In search of disease-modifying treatments for the Niemann-Pick disease type C (NPC), this Phase II single-arm clinical trial evaluated the safety and efficacy of efavirenz, a reverse transcriptase inhibitor ...
  • Sharp increase in the incidence and severity of invasive Streptococcus pyogenes infections in children after the COVID-19 pandemic (2019-2023): A nationwide multicenter study 
    Cobo-Vázquez, Elvira; Aguilera-Alonso, David; Grandioso-Vas, David; Gamell, Anna; Rello-Saltor, Victoria; Oltra-Benavent, Manuel; Cervantes-Hernández, Eloisa; Sanz-Santaeufemia, Francisco; Carrasco-Colom, Jaime; Manzanares-Casteleiro, Ángela; Martín-Pedraz, Laura; Ramírez-de-Arellano, Eva; Falcon-Neira, Lola; Martínez-Campos, Leticia; Colino-Gil, Elena; Jiménez-Montero, Beatriz; Calavia, Olga; Hernández-Ventura, Anna; Del-Castillo-Navio, Elena; Matias-del-Pozo, Vanesa; Calle-Miguel, Laura; Soto, Beatriz; Fernández, Berta; Camil-Olteanu, Filip; Pareja-León, Marta; López-Segura, Nuria; Ara-Montojo, Fátima; Ruiz-Sáez, Beatriz; Calvo-Monge, Cristina; Sánchez-Codez, María; Reinoso, Teresa; Badillo, Katie; Vázquez, Carmen; Villalon, Pilar; Oteo-Iglesias, Jesús; Mellado-Sola, Isabel; Cercenado, Emilia; Blázquez-Gamero, Daniel; Menasalvas-Ruiz, Ana-Isabel; González-Abad, María-José; Guarch, Borja; Ibáñez-Alcalde, Mercedes; Carazo, Begoña; Lung, Mayli; Calvo, Cristina; Saavedra-Lozano, Jesús (ELSEVIER SCI LTD, 2025-10)
    OBJECTIVES: A global surge in pediatric invasive group A streptococcal infection (iGAS) was reported after autumn 2022. This study analyzed the epidemiology and severity of iGAS in Spain, comparing two periods; P1: ...
  • Severe Neutropenia in Infants With Congenital Cytomegalovirus on Antiviral Therapy 
    Papaevangelou, Vassiliki; Pedrero-Tome, Roberto; Syridou, Garyfallia; Baquero-Artigao, Fernando; Rodriguez-Molino, Paula; del Rosal, Teresa; Noguera-Julian, Antoni; Rios-Barnes, Maria; Fortuny, Claudia; Villaverde, Serena; Frick, Maria Antoinnette; Vallejo, Beatriz Alvarez; Soler-Palacin, Pere; Saavedra, Jesus; Karagiannidou, Sofia; Rincon, Elena; Busselo, Itziar Sota; Zuriarrain, Oihana Muga; Calderon, Elisenda Moliner; Tagarro, Alfredo; Malumbres, Maria; Colino, Elena; Llanos, Elisa Garrote; Ruiz, Ana Menasalvas; Mateos, Miguel Sanchez; Espuny, Xavier Bringue; Alonso-Ojembarrena, Almudena; Ferreras-Antolin, Laura; Perez, Irene Cuadrado; Posse, Ana Filgueira; Lyall, Hermione; Blazquez-Gamero, Daniel (LIPPINCOTT WILLIAMS & WILKINS, 2025-11)
    AIM: To describe European real-life experience of severe neutropenia (SN) during ganciclovir (GCV) and/or valganciclovir (VGCV) treatment in infants with congenital cytomegalovirus (cCMV) infection and identify risk factors ...
  • Impact of a community-based educational intervention on the burden and health-related quality of life of informal caregivers 
    Martínez-Melero, Inmaculada; Ruiz-García, María-Jesús; Ruiz-Merino, Guadalupe; García-Rubio, Ana (MOSBY-ELSEVIER, 2025-09)
    BACKGROUND: Caregiving for immobilized patients presents significant challenges that can profoundly impact the mental and physical health of informal caregivers. This study evaluates the impact of a community-based educational ...
  • Sex Differences in Children and Adolescents With Hypertrophic Cardiomyopathy 
    Norrish, Gabrielle; Hall, Kimberley; Field, Ella; Cervi, Elena; Boleti, Olga; Ziolkowska, Lidia; Olivotto, Iacopo; Passantino, Sylvia; Khraiche, Diala; Limongelli, Giuseppe; Weintraub, Robert-G; Anastasakis, Aris; Biagini, Elena; Ragni, Luca; Sarquella-Brugada, Georgia; Cesar, Sergi; Prendiville, Terrence; McLeod, Karen; Ilina, María; Baban, Anwar; Ojala, Tiina-H; Spentzou, Georgia; Bhole, Vinay; Gran, Feran; Brown, Elspeth; Delle-Donne, Grazia; Khodaghalian, Bernadette; Fernández, Adrián; Daubeney, Piers-E-F; Linter, Katie; Kubus, Peter; Uzun, Orhan; Bokenkamp, Regina; Raimondi, Francesca; Marrone, Chiara; Medrano, Constantio; González-López, Esther; Siles, Ana; Luczak-Wozniak, Katarzyna; Bharucha, Tara; Adwani, Satish; Klaassen, Sabine; Castro, Fernando-J; Guereta, Luis; Yamazawa, Hirokuni; Sinagra, Gianfranco; Popoiu, Anca; Perin, Francesca; Chana, B; De-Wilde, Hans; Rasmussen, Torsten-B; Mogensen, Jens; Mathur, Sujeev; Centeno, Fernando; Reinhardt, Zdenka; Barriales-Villa, Roberto; Kubo, Toru; Felice, Tiziana; Radulescu, Cristina; Schouvey, Sylvie; Chaker, Melissa; Kaski, Juan-Pablo (ELSEVIER, 2025-08)
    BACKGROUND: Sex differences have been described in adults with hypertrophic cardiomyopathy (HCM), but it is unknown if similar differences exist in childhood-onset disease. OBJECTIVES: This study aimed to investigate the ...
  • Comparative analysis of cryoballoon versus radiofrequency catheter ablation in atrial fibrillation patients with impaired left ventricular ejection fraction 
    Pongratz, J; Kuck, K-h; Metznerc, A; Hink, U; García-Alberola, Arcadio; Borchard, R; Noelker, G; Kuniss, M; Tilz, R-R; Schrickeli, J-W; Thornton, A; Thomas, D; Katus, H-A; Zahn, R; Spitzer, S; Souza, J-J; Brachmann, J; Tebbenjohanns, J; Wu, L-q; Obel, W-P; Groschup, G; Stellbrink, C; Chun, K-R-J; Gerds-Li, J-h; Stanley, A; Gopal, R-R; Lickfett, L; Lubinski, A; Schumacher, B; Steinwender, C; Franke, H-A; Ouarrak, T; Dorwarth, U; Senges, J; Hoffmann, E; Straube, F (ELSEVIER IRELAND LTD, 2025-08)
    BACKGROUND: In selected patients with atrial fibrillation (AF) and impaired left ventricular ejection fraction (LVEF), catheter ablation has been proposed for rhythm control. It is unclear, if cryoballoon (CBA) or ...
  • Lower rate of pancreatobiliary complications after sludge and microlithiasis pancreatitis compared to gallstone pancreatitis 
    Sirtl, Simon; Teodorescu, Bianca; Gilberg, Leónard; Schafer, Arlett; Beyer, Georg; Arnau, Anna; López-Guillén, Pablo; Martínez-Domínguez, Samuel-J; Abad-Baroja, Daniel; Oyon, Daniel; Ruiz-Belmonte, Lara-M; Tejedor-Tejada, Javier; Zapater, Raúl; Martín-Vicente, Noelia; Fernández-Esparcia, Pedro-José; Julián-Gomara, Ana-Belén; Sastre-Lozano, Violeta-María; Manzanares-García, Juan-José; Chivato-Martín-Falquina, Irene; Andrés-Pascual, Laura; Torres-Monclús, Nuria; Zaragoza-Velasco, Natividad; Rojo, Eukene; Lapena-Muñoz, Berta; Flores, Virginia; Díaz-Gómez, Arantxa; Canamares-Orbis, Pablo; Vinzo-Abizanda, Isabel; Carrasco, Natalia-Marcos; Pardo-Grau, Laura; García-Rayado, Guillermo; Millastre-Bocos, Judith; García-García-de-Paredes, Ana; Vaamonde-Lorenzo, María; Izaguirre-Arostegi, Arantzazu; Lozada-Hernández, Edgard-Efren; Velarde-Ruiz-Velasco, José-Antonio; Zorniak, Michal; de-Madaria, Enrique; Mayerle, Julia; Velamazan, Raúl (ELSEVIER SCIENCE INC, 2025-09)
    BACKGROUND AND AIMS: Cholecystectomy is recommended to prevent recurrence of biliary pancreatitis, but supporting evidence is limited for sludge- and microlithiasis-induced acute pancreatitis (AP). This study aimed to ...
  • MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer 
    del Rey-Vergara, Raul; Galindo-Campos, Miguel Alejandro; Rocha, Pedro; Carpes, Marina; Martinez, Carlos; Masfarre, Laura; Menendez, Silvia; Quimis, Fabricio; Rossell, Adria; Inanez, Albert; Perez-Buira, Sandra; Rojo, Federico; Gimeno, Ramon; Isla, Dolores; Zugazagoitia, Jon; Blanco, Cristina Marti; Garcia-Campelo, Rosario; Moreno-Vega, Alberto; Leon-Mateos, Luis; Mellen, Angel Callejo; Park, Kwon-Sik; Heeke, Simon; Heymach, John V.; Taus, Alvaro; Paz-Ares, Luis; Rovira, Ana; Arriola, Edurne (CELL PRESS, 2025-07)
    The introduction of immunotherapy as a first-line treatment for advanced small cell lung cancer (SCLC) represents significant progress, yet there remains an opportunity to further improve patient outcomes. Hepatocyte growth ...
  • Practical guideline for major hereditary thrombophilia 
    Tang, Liang, V; Morange, Pierre-Emmanuel; Corral, Javier; Ntaios, Georgios; Spyropoulos, Alex C.; Lip, Gregory Y. H.; Douketis, James D. (CELL PRESS, 2025-06)
  • Annotation of biological samples data to standard ontologies with support from large language models 
    Riquelme-García, Andrea; Mulero-Hernández, Juan; Fernández-Breis, Jesualdo-Tomás (ELSEVIER, 2025)
    The semantic integration of biological data is hindered by the vast heterogeneity of data sources and their limited semantic formalization. A crucial step in this process is mapping data elements to ontological concepts, ...
  • A novel explainable AI framework for medical image classification integrating statistical, visual, and rule-based methods 
    Ullah, Naeem; Guzmán-Aroca, Florentina; Martínez-Álvarez, Francisco; De-Falco, Ivanoe; Sannino, Giovanna (ELSEVIER, 2025-10)
    Artificial intelligence and deep learning are powerful tools for extracting knowledge from large datasets, particularly in healthcare. However, their black-box nature raises interpretability concerns, especially in high-stakes ...
  • Moderate-to-severe hypercalcemia secondary to primary hyperparathyroidism refractory to conventional treatment (therapeutic management with denosumab): case report and literature review 
    Carpio-Salmerón, Manuel; Tebar-Caballero, Mariano; Marín-Martínez, Luis; Marco-Alacid, Cristian (AFRICAN FIELD EPIDEMIOLOGY NETWORK-AFENET, 2025)
    Severe hypercalcemia resistant to conventional medical treatment is a rare complication of primary hyperparathyroidism, and published information on the use of denosumab in patients with this condition is limited. This ...