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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Experience with tocilizumab in patients with neuromyelitis optica spectrum disorders 
    Carreon-Guarnizo, Ester; Hernández-Clares, R; Castillo-Trivino, T; Meca-Lallana, V; Arocas-Casan, V; Iniesta-Martínez, F; Olascoaga-Urtaza, J; Meca-Lallana, J-E (ELSEVIER ESPANA SLU, 2022-04)
    INTRODUCTION: Neuromyelitis optica spectrum disorders (NMOSD) are immune-mediated inflammatory disorders of the central nervous system involving astrocytes, B lymphocytes, anti-aquaporin 4, and such inflammatory mediators ...
  • Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study 
    Freisling, Heinz; Viallon, Vivian; Lennon, Hannah; Bagnardi, Vincenzo; Ricci, Cristian; Butterworth, Adam-S; Sweeting, Michael; Muller, David; Romieu, Isabelle; Bazelle, Pauline; Kvaskoff, Marina; Arveux, Patrick; Severi, Gianluca; Bamia, Christina; Kuehn, Tilman; Kaaks, Rudolf; Bergmann, Manuela; Boeing, Heiner; Tjonneland, Anne; Olsen, Anja; Overvad, Kim; Dahm, Christina-C; Menéndez, Virginia; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Santiuste, Carmen; Barricarte-Gurrea, Aurelio; Tong, Tammy-Y-N; Schmidt, Julie-A; Tzoulaki, Ioanna; Tsilidis, Konstantinos-K; Ward, Heather; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Ricceri, Fulvio; Panico, Salvatore; Picavet, H-Susan-J; Bakker, Marije; Monninkhof, Evelyn; Nilsson, Peter; Manjer, Jonas; Rolandsson, Olov; Thysell, Elin; Weiderpass, Elisabete; Jenab, Mazda; Riboli, Elio; Vineis, Paolo; Danesh, John; Wareham, Nick-J; Gunter, Marc-J; Ferrari, Pietro (BMC, 2020-01-10)
    BACKGROUND: Although lifestyle factors have been studied in relation to individual non-communicable diseases (NCDs), their association with development of a subsequent NCD, defined as multimorbidity, has been scarcely ...
  • Validation of self-reported perception of proximity to industrial facilities: MCC-Spain study 
    Castello, Adela; Pérez-Gómez, Beatriz; Lora-Pablos, David; Lope, Virginia; Castano-Vinyals, Gemma; Vitelli-Storelli, Facundo; Dierssen-Sotos, Trinidad; Amiano, Pilar; Guevara, Marcela; Moreno, Victor; Lozano-Lorca, Macarena; Tardon, Adonina; Alguacil, Juan; Hernández-García, Marta; Marcos-Gragera, Rafael; Chirlaque-López, María-Dolores; Ardanaz, Eva; Ibarluzea, Jesús; Gómez-Acebo, Ines; Molina, Antonio-J; O'Callaghan-Gordo, Cristina; Aragonés, Nuria; Kogevinas, Manolis; Pollan, Marina; García-Pérez, Javier (PERGAMON-ELSEVIER SCIENCE LTD, 2020-02)
    BACKGROUND: Self-reported data about environmental exposures can lead to measurement error. OBJECTIVES: To validate the self-reported perception of proximity to industrial facilities. METHODS: MCC-Spain is a population-based ...
  • Retrospective Multicenter Study of Extracorporeal Photopheresis in Steroid-Refractory Acute and Chronic Graft-versus-Host Disease 
    Oarbeascoa, Gillen; Lozano, María-Luisa; Guerra, Luisa-María; Amunarriz, Cristina; Andon-Saavedra, Concepcion; García-Gala, José-María; Viejo, Aurora; Revilla, Nuria; Acosta-Fleitas, Cynthia; Luis-Arroyo, José; Martínez-Revuelta, Eva; Galego, Andrea; Hernández-Maraver, Dolores; Kwon, Mi; Diez-Martín, José-Luis; Pascual, Cristina (ELSEVIER SCIENCE INC, 2020-04)
    Extracorporeal photopheresis (ECP) is an established treatment strategy in steroid-refractory graft-versus-host disease (GVHD). This study's main objective was to analyze the clinical response and impact of ECP therapy in ...
  • Sagittal spinal morphotype assessment in 8 to 15 years old Inline Hockey players 
    Sainz-de-Baranda, Pilar; Cejudo, Antonio; Moreno-Alcaraz, Victor-Jesús; Martínez-Romero, María-Teresa; Aparicio-Sarmiento, Alba; Santonja-Medina, Fernando (PEERJ INC, 2020-01-02)
    BACKGROUND: Physiological sagittal spinal curvatures play an important role in health and performance in sports. For that reason, several scientific studies have assessed spinal morphology in young athletes. However, to ...
  • A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia 
    Arriazu, Elena; Vicente, Carmen; Pippa, Raffaella; Peris, Irene; Martínez-Balsalobre, Elena; García-Ramírez, Patricia; Marcotegui, Nerea; Igea, Ana; Alignani, Diego; Rifon, José; Mateos, María-C; Cayuela, María-Luisa; Nebreda, Ángel-R; Odero, María-D (NATURE PUBLISHING GROUP, 2020-01-08)
    Acute myeloid leukemia (AML) is an aggressive hematologic malignancy. Although novel emerging drugs are available, the overall prognosis remains poor and new therapeutic approaches are required. PP2A phosphatase is a key ...
  • Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma 
    Molina, María-L; García-Bernal, David; Martínez, Salvador; Valdor, Rut (MDPI, 2020-01)
    Glioblastoma (GB) has been shown to up-regulate autophagy with anti- or pro-oncogenic effects. Recently, our group has shown how GB cells aberrantly up-regulate chaperone-mediated autophagy (CMA) in pericytes of peritumoral ...
  • Efficacy and safety of D,L-3-hydroxybutyrate (D,L-3-HB) treatment in multiple acyl-CoA dehydrogenase deficiency 
    van-Rijt, Willemijn-J; Jager, Emmalie-A; Allersma, Derk-P; Zeybek, A-Cigdem-Aktuglu; Bhattacharya, Kaustuv; Debray, Francois-Guillaume; Ellaway, Carolyn-J; Gautschi, Matthias; Geraghty, Michael-T; Gil-Ortega, David; Larson, Austin-A; Moore, Francesca; Morava, Eva; Morris, Andrew-A; Oishi, Kimihiko; Schiff, Manuel; Scholl-Buergi, Sabine; Tchan, Michel-C; Vockley, Jerry; Witters, Peter; Wortmann, Saskia-B; van-Spronsen, Francjan; Van-Hove, Johan-L-K; Derks, Terry-G-J (ELSEVIER SCIENCE INC, 2020-05)
    PURPOSE: Multiple acyl-CoA dehydrogenase deficiency (MADD) is a life-threatening, ultrarare inborn error of metabolism. Case reports described successful D,L-3-hydroxybutyrate (D,L-3-HB) treatment in severely affected MADD ...
  • Immunisation schedule of the Spanish Association of Paediatrics: 2020 recommendations 
    Álvarez-García, Francisco-José; Cilleruelo-Ortega, María-José; Álvarez-Aldean, Javier; Garces-Sánchez, María; García-Sánchez, Nuria; Garrote-Llanos, Elisa; Hernández-Merino, Ángel; Iofrio-de-Arce, Antonio; Merino-Moina, Manuel; Montesdeoca-Melian, Abian; Navarro-Gómez, María-Luisa; Ruiz-Contreras, Jesús (EDICIONES DOYMA S A, 2020-01)
    The CAV-AEP annually publishes the immunisation schedule considered optimal for all children resident in Spain, taking into account the available evidence. The 2+1 schedule is recommended (2, 4, and 11 months) with hexavalent ...
  • Questionnaires of person centered care in primary care. A systematic review 
    Pascual-López, José-Antonio; Gil-Pérez, Trinidad; Sánchez-Sánchez, Juan-Antonio; Menarguez-Puche, Juan-Francisco (EDICIONES DOYMA S A, 2020-12)
    OBJECTIVE: Despite the acknowledged importance of 'Person Centered Care' (PCC), there are obvious limitations for its determination and measurement due to the difficulty of its exact definition. The objective of our review ...
  • Association of Body Mass Index With Clinical Outcomes in Patients With Atrial Fibrillation: A Report From the FANTASIIA Registry 
    Bertomeu-González, Vicente; Moreno-Arribas, José; Esteve-Pastor, María-Asuncion; Roldán-Rabadán, Inmaculada; Muniz, Javier; Rana-Miguez, Paula; Ruiz-Ortiz, Martín; Cequier, Ángel; Bertomeu-Martínez, Vicente; Badimon, Lina; Anguita, Manuel; Lip, Gregory-Y-H; Marín, Francisco (WILEY, 2020-01-07)
    Background Obesity and atrial fibrillation (AF) frequently coexist and independently increase mortality. We sought to assess the association between obesity and adverse events in patients receiving oral anticoagulants for ...
  • Why and how keep in mind cannabis in our smoking outpatients? 
    Olano-Espinosa, Eduardo; Lozano-Polo, Adelaida; Grifell-Guardia, Marc; Pinet-Ogue, María-Cristina; Isorna-Folgar, Manuel; Moreno-Arnedillo, José-Javier; Álvarez-Roldan, Arturo; Amatller-Gutiérrez, Otger; Caudevilla-Galligo, Fernando; Esteban-Herrera, Ana; German-Mancebo, Isabel; Minguez-López, Olga; Palmerin-García, Ana; Pinet-Ogue, Ma-Cristina; Salto-Cerezuela, Esteve; Sánchez-Martínez, Francesca; Suelves-i-Joanxich, Josép-María; Uriguen-Echeverria, Leyre; Zabala-Galan, Joséba (EDICIONES DOYMA S A, 2020-01)
    EVICT project has noted the increase in cannabis use in the Spanish youth population, and has studied its association with tobacco, concluding that: It has an influence in the learning to smoke process: The beginning can ...
  • Spanish Cell Therapy Network (TerCel): 15 years of successful collaborative translational research 
    Sánchez-Guijo, Fermin; García-Olmo, Damian; Prosper, Felipe; Martínez, Salvador; Zapata, Agustin; Fernández-Aviles, Francisco; Toledo-Aral, Juan-José; Torres, Miguel; Farinas, Isabel; Badimon, Lina; Labandeira-García, José-Luis; García-Sancho, Javier; Moraleda, José-María (ELSEVIER SCI LTD, 2020-01)
    In the current article we summarize the 15-year experience of the Spanish Cell Therapy Network (TerCel), a successful collaborative public initiative funded by the Spanish government for the support of nationwide translational ...
  • Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease 
    Sánchez-Campillo, María; Ruiz-Pastor, María-José; Gazquez, Antonio; Marín-Muñoz, Juan; Noguera-Perea, Fuensanta; Ruiz-Alcaraz, Antonio-J; Manzanares-Sánchez, Salvadora; Antúnez-Almagro, Carmen; Larque, Elvira (MDPI, 2020-01-01)
    The protein Major Facilitator Superfamily Domain containing 2A (MFSD2a) was recently described as the primary carrier for docosahexaenoic acid (DHA) into the brain. Alzheimer's disease (AD) is a progressive neurodegenerative ...
  • Rational use of antimicrobials in the treatment of upper airway infections 
    Alfayate-Miguelez, Santiago; García-Marcos, Luis (SOC BRASIL PEDIATRIA, 2020-03)
    OBJECTIVE: To analyze the main cause of the irresponsible use of antibiotics at the pediatric level in a very frequent, usually self-limited, and typically viral condition: upper airway respiratory infections. SOURCES: ...
  • RNA sequencing-based transcriptome profiling of cardiac tissue implicates novel putative disease mechanisms in FLNC-associated arrhythmogenic cardiomyopathy 
    Hall, Charlotte-L; Gurha, Priyatansh; Sabater-Molina, María; Asimaki, Ángeliki; Futema, Marta; Lovering, Ruth-C; Paz-Suárez, Mari; Aguilera, Beatriz; Molina, Pilar; Zorio, Esther; Coarfa, Cristian; Robertson, Matthew-J; Cheedipudi, Sirisha-M; Ng, Keat-eng; Delaney, Paul; Hernández, Juan-Pedro; Pastor, Francisco; Gimeno, Juan-R; McKenna, William-J; Marian, Ali-J; Syrris, Petros (ELSEVIER IRELAND LTD, 2020-03-01)
    Arrhythmogenic cardiomyopathy (ACM) encompasses a group of inherited cardiomyopathies including arrhythmogenic right ventricular cardiomyopathy (ARVC) whose molecular disease mechanism is associated with dysregulation of ...
  • Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices 
    Lillo-Castellano, José-María; González-Ferrer, Juan-José; Marina-Breysse, Manuel; Martínez-Ferrer, José-Bautista; Pérez-Álvarez, Luisa; Alzueta, Javier; Gabriel-Martínez, Juan; Rodríguez, Anibal; Rodríguez-Pérez, Juan-Carlos; Anguera, Ignasi; Vinolas, Xavier; García-Alberola, Arcadio; Quintanilla, Jorge-G; Alfonso-Almazan, José-Manuel; García, Javier; Borrego, Luis; Canadas-Godoy, Victoria; Pérez-Castellano, Nicasio; Pérez-Villacastín, Julian; Jiménez-Diaz, Javier; Jalife, José; Filgiras-Rama, Davidue (OXFORD UNIV PRESS, 2020-05)
    AIMS: Atrial electrical remodelling (AER) is a transitional period associated with the progression and long-term maintenance of atrial fibrillation (AF). We aimed to study the progression of AER in individual patients with ...
  • Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry 
    Mena-Vázquez, Natalia; Fernández-Nebro, Antonio; Pego-Reigosa, José-María; Galindo, María; Melissa-Anzola, Ana; Uriarte-Isacelay, Esther; Olive-Marques, Alejandro; Aurrecoechea, Elena; Freire, Mercedes; Tomero, Eva; García-Villanueva, María-Jesús; Stoye, Claudia; Salas-Heredia, Esteban; Bernal-Vidal, José-Antonio; Salgado, Eva; Blanco, Ricardo; Javier-Novoa, Francisco; Ibanez-Barcelo, Mónica; Torrente-Segarra, Vicente; Narvaez, Javier; Calvet, Joan; Moriano-Morales, Clara; Vázquez-Rodríguez, Tomás-Ramón; García-de-la-Pena, Paloma; Bohórquez, Cristina; Andreu-Sánchez, José-Luis; Cobo-Ibanez, Tatiana; Bonilla, Gema; Lozano-Rivas, Nuria; Montilla, Carlos; Javier-Toyos, Francisco; Marenco-De-la-Fuente, José-Luis; Exposito, Lorena; Ruiz-Lucea, María-Esther; Vals, Elia; Manero-Ruiz, Javier; Bernal-Vidal, José-Antonio; Rua-Figueroa, Inigo (OXFORD UNIV PRESS, 2020-08)
    OBJECTIVES: This article estimates the frequency of polyautoimmunity and associated factors in a large retrospective cohort of patients with SLE. METHODS: RELESSER (Spanish Society of Rheumatology Lupus Registry) is a ...
  • Markers of endothelial cell activation and neutrophil extracellular traps are elevated in immune thrombocytopenia but are not enhanced by thrombopoietin receptor agonists 
    Garabet, Lamya; Henriksson, Carola-E; Lozano, María-Luisa; Ghanima, Waleed; Bussel, James; Brodin, Ellen; Fernández-Pérez, María-Piedad; Martínez, Constantino; González-Conejero, Rocío; Mowinckel, Marie-Christine; Sandset, Per-Morten (PERGAMON-ELSEVIER SCIENCE LTD, 2020-01)
    INTRODUCTION: Patients with immune thrombocytopenia (ITP) are at increased risk of thrombosis, which seems to be further enhanced by treatment with thrombopoietin-receptor-agonists (TPO-RAs). The underlying mechanisms of ...
  • Phase III Trial of Adjuvant Capecitabine After Standard Neo-/Adjuvant Chemotherapy in Patients With Early Triple-Negative Breast Cancer (GEICAM/2003-11_CIBOMA/2004-01) 
    Lluch, Ana; Barríos, Carlos-H; Torrecillas, Laura; Ruiz-Borrego, Manuel; Bines, José; Segalla, José; Guerrero-Zotano, Ángel; García-Saenz, José-A; Torres, Roberto; de-la-Haba, Juan; García-Martínez, Elena; Gómez, Henry-L; Llombart, Antonio; Salvador-Bofill, Javier; Baena-Canada, José-M; Barnadas, Agusti; Calvo, Lourdes; Pérez-Michel, Laura; Ramos, Manuel; Fernández, Isaura; Rodríguez-Lescure, Alvaro; Cardenas, Jesús; Vinholes, Jeferson; Martínez-de-Dueñas, Eduardo; Godes, María-J; Segui, Miguel-A; Anton, Antonio; López-Álvarez, Pilar; Moncayo, Jorge; Amorim, Gilberto; Villar, Esther; Reyes, Salvador; Sampaio, Carlos; Cardemil, Bernardita; Escudero, María-J; Bezares, Susana; Carrasco, Eva; Martín, Miguel; Corona, J; Jara, C; Cardemil, B; Toro, R; Pimentel, C; Hernando, B; Vicente, E; Zagame, L; Gil, M; García-Estevez, L; Rodríguez, C; de-la-Cruz, M-A; Tello, J-M; Campos, S; Lomas, M; Capdevile, D; Campos, M; Margeli, M; Andrés, R; Tusquets, I; Ballesteros, A; Guerrero, A; Arguello, M; Rodríguez, J-L; Muñoz, M; Florian, J; Azevedo, S; Mondragon, R; Peralta, J; Palomo, A-E; Barajas, L-J; Arcusa, A; Carranza, H; García, C; Umbria, C; Ales, José-E; López-Vega, J-M; Romeo, M; Valero, J; Alonso, J-L; Mathias, C; Gutiérrez, F; Adrover, E; Nunez, P; Mendiola, C; Cassinello, J; de-la-Huerta, A (AMER SOC CLINICAL ONCOLOGY, 2020-01-20)
    PURPOSE: Operable triple-negative breast cancers (TNBCs) have a higher risk of relapse than non-TNBCs with standard therapy. The GEICAM/2003-11_CIBOMA/2004-01 trial explored extended adjuvant capecitabine after completion ...