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Repositorio Institucional en Ciencias de la Salud de la Región Murcia: Envíos recientes

  • Spatial and Pregnancy-Related Changes in the Protein, Amino Acid, and Carbohydrate Composition of Bovine Oviduct Fluid 
    Rodríguez-Alonso, Beatriz; Maillo, Verónica; Salvador-Acuna, Omar; López-Ubeda, Rebeca; Torrecillas, Alejandro; Simintiras, Constantine-A; Sturmey, Roger; Aviles, Manuel; Lonergan, Patrick; Rizos, Dimitrios (MDPI, 2020-03)
    Knowledge of how the biochemical composition of the bovine oviduct is altered due to the oviduct anatomy or the presence of an embryo is lacking. Thus, the aim of this study was to assess the effect of (?) oviduct anatomy ...
  • A New Treatment for Mammillary Fistulas Using Ultrasound-Guided Percutaneous Needle Electrolysis 
    Berna-Serna, Juan-de-Dios; García-Vidal, José-Antonio; Escolar-Reina, María-P; Medina-Mirapeix, Francesc; Guzman-Aroca, Florentina; Piñero-Madrona, Antonio; Berna-Mestre, Juan-de-Dios (MDPI, 2020-03)
    The aim of this study was to investigate the efficacy of ultrasound-guided percutaneous needle electrolysis (PNE) in mammillary fistulas (MFs). A prospective study was performed in 18 patients with MF who were treated with ...
  • Expression of tert Prevents ALT in Zebrafish Brain Tumors 
    Idilli, Aurora-Irene; Cusanelli, Emilio; Pagani, Francesca; Berardinelli, Francesco; Bernabé, Manuel; Cayuela, María-Luisa; Poliani, Pietro-Luigi; Mione, María-Caterina (FRONTIERS MEDIA SA, 2020-02-11)
    The activation of a telomere maintenance mechanism (TMM) is an essential step in cancer progression to escape replicative senescence and apoptosis. Alternative lengthening of telomeres (ALT) is found in a subset of malignant ...
  • Child Head Circumference and Placental MFSD2a Expression Are Associated to the Level of MFSD2a in Maternal Blood During Pregnancy 
    Sánchez-Campillo, María; Ruiz-Palacios, María; Ruiz-Alcaraz, Antonio-J; Prieto-Sánchez, María-Teresa; Blanco-Carnero, José-Eliseo; Zornoza, Matilde; Ruiz-Pastor, María-José; Demmelmair, Hans; Sánchez-Solis, Manuel; Koletzko, Berthold; Larque, Elvira (FRONTIERS MEDIA SA, 2020)
    Gestational diabetes mellitus (GDM) is a world-wide health challenge, which prevalence is expected to increase in parallel to the epidemic of obesity. Children born from GDM mothers have lower levels of docosahexaenoic ...
  • Living Without Temporal Cues: A Case Study 
    Bonmati-Carrion, María-Ángeles; Revell, Victoria-L; Cook, Tom-J; Welch, Thomas-R-E; Rol, María-Ángeles; Skene, Debra-J; Madrid, Juan-Antonio (FRONTIERS MEDIA SA, 2020-02-07)
    Isolation from external time cues allows endogenous circadian rhythmicity to be demonstrated. In this study, also filmed as a television documentary, we assessed rhythmic changes in a healthy man time isolated in a bunker ...
  • A quality improvement cycle of the care process in a general surgery hospitalization ward 
    Azorin-Samper, María-del-Carmen; Aguilar-Jiménez, José; Flores-Pastor, Benito; Aguayo-Albasini, José-L (MEXICAN ACAD SURGERY, 2020-03)
    BACKGROUND: There could be important failures in clinical data and plan records that potentially influence the surgical care process. OBJECTIVE: To complete a quality of care improvement cycle on the surgical care process ...
  • Urban air pollution and hospital admissions for asthma and acute respiratory disease in Murcia city (Spain) 
    Ortega-García, Juan-Antonio; Martínez-Hernández, Indra; Boldo, Elena; Cárceles-Álvarez, Alberto; Solano-Navarro, Carmen; Ramis, Rebeca; Aguilar-Ros, Estefania; Sánchez-Solis, Manuel; López-Hernández, Fernando (EDICIONES DOYMA S A, 2020-08)
    INTRODUCTION: Urban air pollution is a major threat to child and adolescent health. Children are more vulnerable to its effects, being associated with higher morbidity and mortality due to acute and chronic diseases, ...
  • Management of patients with heart failure treated in cardiology consultations: IC-BERG Study 
    Barríos, V; Escobar, C; Ortiz-Cortes, C; Cosin-Sales, J; Pascual-Figal, Domingo-Andrés; García-Moll-Marimon, X (EDICIONES DOYMA S A, 2020-08)
    OBJECTIVE: To determine the perception and management of heart failure with reduced ejection fraction (HFrEF) by clinical cardiologists and to establish a consensus with recommendations. METHODS: We employed the modified ...
  • Non-Pharmacological Interventions for Reducing Anxiety in Patients with Potentially Malignant Oral Disorders 
    López-Yufera, Elia; López-Jornet, Pia; Toralla, Oscar; Pons-Fuster-López, Eduardo (MDPI, 2020-03)
    OBJECTIVE: To evaluate the effect of a music intervention upon anxiety, blood pressure, and heart rate in adult patients with potentially malignant oral disorders. METHODS: Eighty consecutive adults (mean age: 68.3 years) ...
  • Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length 
    Li, Chen; Stoma, Svetlana; Lotta, Luca-A; Warner, Sophie; Albrecht, Eva; Allione, Alessandra; Arp, Pascal-P; Broer, Linda; Buxton, Jessica-L; Alves, Alexessander-Da-Silva-Couto; Deelen, Joris; Fedko, Iryna-O; Gordon, Scott-D; Jiang, Tao; Karlsson, Robert; Kerrison, Nicola; Loe, Taylor-K; Mangino, Massimo; Milaneschi, Yuri; Miraglio, Benjamin; Pervjakova, Natalia; Russo, Alessia; Surakka, Ida; van-der-Spek, Ashley; Verhoeven, Josine-E; Amin, Najaf; Beekman, Marían; Blakemore, Alexandra; Canzian, Federico; Hamby, Stephen-E; Hottenga, Jouke-Jan; Jones, Peter-D; Jousilahti, Pekka; Magi, Reedik; Medland, Sarah-E; Montgomery, Grant-W; Nyholt, Dale-R; Perola, Markus; Pietilainen, Kirsi-H; Salomaa, Veikko; Sillanpaa, Elina; Suchiman, H-Eka; van-Heemst, Diana; Willemsen, Gonneke; Agudo, Antonio; Boeing, Heiner; Boomsma, Dorret; Chirlaque-López, María-Dolores; Fagherazzi, Guy; Ferrari, Pietro; Franks, Paul; Gieger, Christian; Eriksson, Johan-Gunnar; Gunter, Marc; Hagg, Sara; Hovatta, Iiris; Imaz, Liher; Kaprio, Jaakko; Kaaks, Rudolf; Key, Timothy-J; Krogh, Vittorio; Martín, Nicholas-G; Melander, Olle; Metspalu, Andrés; Moreno, Concha; Onland-Moret, N-Charlotte; Nilsson, Peter; Ong, Ken-K; Overvad, Kim; Palli, Domenico; Panico, Salvatore; Pedersen, Nancy-L; Penninx, Brenda-W-J-H; Ramon-Quiros, J; Riitta-Jarvelin, Marjo; Rodríguez-Barranco, Miguel; Scott, Robert-A; Severi, Gianluca; Slagboom, P-Eline; Spector, Tim-D; Tjonneland, Anne; Trichopoulou, Antonia; Tumino, Rosario; Uitterlinden, Andre-G; van-der-Schouw, Yvonne-T; van-Duijn, Cornelia-M; Weiderpass, Elisabete; Denchi, Eros-Lazzerini; Matullo, Giuseppe; Butterworth, Adam-S; Danesh, John; Samani, Nilesh-J; Wareham, Nicholas-J; Nelson, Christopher-P; Langenberg, Claudia; Codd, Veryan (CELL PRESS, 2020-03-05)
    Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed association results across large-scale ...
  • Immunotherapy with CAR-T cells in paediatric haematology-oncology 
    Mirones, Isabel; Moreno, Lucas; Patino-García, Ana; Lizeaga, Garbine; Moraleda, José-María; Lozano, María-Luisa; Pérez-Martínez, Antonio (EDICIONES DOYMA S A, 2020-07)
    Despite being a rare disease, cancer is the first cause of mortality due to disease during the paediatric age in the developed countries. The current, great increase in new treatments, such as immunotherapy, constitutes a ...
  • The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries 
    Tong, Tammy-Y-N; Appleby, Paul-N; Key, Timothy-J; Dahm, Christina-C; Overvad, Kim; Olsen, Anja; Tjonneland, Anne; Katzke, Verena; Kuhn, Tilman; Boeing, Heiner; Karakatsani, Anna; Peppa, Eleni; Trichopoulou, Antonia; Weiderpass, Elisabete; Masala, Giovanna; Grioni, Sara; Panico, Salvatore; Tumino, Rosario; Boer, Jolanda-M-A; Verschuren, W-M-Monique; Quiros, J-Ramon; Agudo, Antonio; Rodríguez-Barranco, Miguel; Imaz, Liher; Chirlaque-López, María-Dolores; Moreno-Iribas, Conchi; Engstrom, Gunnar; Sonestedt, Emily; Lind, Marcus; Otten, Julia; Khaw, Kay-Tee; Aune, Dagfinn; Riboli, Elio; Wareham, Nicholas-J; Imamura, Fumiaki; Forouhi, Nita-G; di-Angelantonio, Emanuele; Wood, Ángela-M; Butterworth, Adam-S; Pérez-Cornago, Aurora (OXFORD UNIV PRESS, 2020-07-21)
    AIM: To investigate the associations between major foods and dietary fibre with subtypes of stroke in a large prospective cohort. METHODS AND RESULTS: We analysed data on 418 329 men and women from nine European countries, ...
  • New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells 
    Alburquerque-González, Begoña; Bernabé-García, Manuel; Montoro-García, Silvia; Bernabé-García, Ángel; Rodrigues, Priscila-Campioni; Ruiz-Sanz, Javier; López-Calderón, Fernando-F; Luque, Irene; Nicolas, Francisco-José; Cayuela, María-Luisa; Salo, Tuula; Pérez-Sánchez, Horacio; Conesa-Zamora, Pablo (SPRINGERNATURE, 2020-02)
    Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional colorectal carcinoma (CRC), and is characterized by frequent resistance to anti-epidermal growth factor receptor (EGFR) and overexpression ...
  • Improvement of the Flavanol Profile and the Antioxidant Capacity of Chocolate Using a Phenolic Rich Cocoa Powder 
    González-Barrio, Rocío; Nunez-Gómez, Vanesa; Cienfuegos-Jovellanos, Elena; García-Alonso, Francisco-Javier; Periago-Caston, Ma-Jesús (MDPI, 2020-02)
    Chocolate is made from cocoa, which is rich in (poly)phenols that have a high antioxidant capacity and are associated with the prevention of chronic diseases. In this study, a new production process was evaluated in order ...
  • Novel CYP4F22 mutations associated with autosomal recessive congenital ichthyosis (ARCI). Study of the CYP4F22 c.1303C>T founder mutation 
    Esperon-Moldes, Uxia; Ginarte-Val, Manuel; Rodríguez-Pazos, Laura; Fachal, Laura; Martín-Santiago, Ana; Vicente, Asuncion; Jiménez-Gallo, David; Guillén-Navarro, Encarna; Martorell-Sampol, Loreto; González-Ensenat, María-Antonia; Vega, Ana (PUBLIC LIBRARY SCIENCE, 2020-02-18)
    Mutations in CYP4F22 cause autosomal recessive congenital ichthyosis (ARCI). However, less than 10% of all ARCI patients carry a mutation in CYP4F22. In order to identify the molecular basis of ARCI among our patients (a ...
  • Potential Survival Benefit for Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation after Nivolumab Therapy for Relapse/Refractory Hodgkin Lymphoma: Real-Life Experience in Spain 
    Martínez, Carmen; Carpio, Cecilia; Heras, Inmaculada; Ríos-Herranz, Eduardo; Buch, Joan; Gutiérrez, Antonio; Romero, Samuel; Zeberio, Izaskun; García-García, Irene; Rodríguez-Izquierdo, Antonia; Alonso, Rosalia; Bargay, Joan; Barrenetxea, Cristina; Domingo-Domenech, Eva; Espeso-de-Haro, Manuel; Palomera, Luis; García-Sanz, Ramon (ELSEVIER SCIENCE INC, 2020-08)
    Clinical trials have shown that nivolumab has remarkable activity against relapsed/refractory classical Hodgkin lymphoma (cHL). However, the role of allogeneic hematopoietic stem cell transplantation (allo-HSCT) as ...
  • Neprilysin inhibition, endorphin dynamics, and early symptomatic improvement in heart failure: a pilot study 
    Revuelta-López, Elena; Nunez, Julio; Gastelurrutia, Paloma; Cediel, German; Januzzi, James-L; Ibrahim, Nasrien-E; Emdin, Michele; VanKimmenade, Roland; Pascual-Figal, Domingo-Andrés; Nunez, Eduardo; Gommans, Frank; Lupon, Josép; Bayes-Genis, Antoni (WILEY PERIODICALS, INC, 2020-04)
    AIM: Sacubitril/valsartan is a first-in-class angiotensin receptor-neprilysin inhibitor developed for the treatment of heart failure with reduced ejection fraction. Its benefits are achieved through the inhibition of ...
  • Melatonin as an Agent for Direct Pulp-Capping Treatment 
    Guerrero-Gironés, Julia; Alcaina-Lorente, Antonia; Ortiz-Ruiz, Clara; Ortiz-Ruiz, Eduardo; Pecci-Lloret, María-P; Rodríguez-Lozano, Francisco-Javier; Martínez, Carlos-M; Ortiz-Ruiz, Antonio-José (MDPI, 2020)
    Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts. This research aimed to evaluate the pulp response to melatonin ...
  • A Critical Mutualism - Competition Interplay Underlies the Loss of Microbial Diversity in Sedentary Lifestyle 
    Castellanos, Nazareth; Diez, Gustavo-G; Antúnez-Almagro, Carmen; Bailén, María; Bressa, Carlo; González-Soltero, Rocío; Pérez, Margarita; Larrosa, Mar (FRONTIERS MEDIA SA, 2020-01-22)
    Physical exercise improves the overall health status by preventing the development of several diseases. In recent years, it has been observed that physical exercise impacts gut microbiota by increasing the presence of ...
  • A pediatric regimen for adolescents and young adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: Results of the ALLRE08 PETHEMA trial 
    Ribera, Josép-María; Morgades, Mireia; Montesinos, Pau; Tormo, Mar; Martínez-Carballeira, Daniel; González-Campos, José; Gil, Cristina; Barba, Pere; García-Boyero, Raimundo; Coll, Rosa; Pedreño, María; Ribera, Jordi; Mercadal, Santiago; Vives, Susana; Novo, Andrés; Genesca, Eulalia; Hernández-Rivas, Jesús-María; Bergua, Juan; Amigo, María-Luz; Vall-Llovera, Ferran; Martínez-Sánchez, Pilar; Calbacho, María; García-Cadenas, Irene; García-Guinon, Antoni; Sánchez-Sánchez, María-José; Cervera, Marta; Feliu, Evarist; Orfao, Alberto (WILEY, 2020-04)
    BACKGROUND: Pediatric-based or -inspired trials have improved the prognosis of adolescents and young adults (AYA) with Philadelphia chromosome-negative (Ph-neg) acute lymphoblastic leukemia (ALL). METHODS: This study reports ...