Navarro-Serna, Sergio; Pineiro-Silva, Celia; Luongo, Chiara; Parrington, John; Romar, Raquel; Gadea, Joaquín
(MDPI, 2022-02)
Mosaicism is the most important limitation for one-step gene editing in embryos by CRISPR/Cas9 because cuts and repairs sometimes take place after the first DNA replication of the zygote. To try to minimize the risk of ...