Repositorio Dspace

Listar por tema "Zebrafish/genetics"

Listar por tema "Zebrafish/genetics"

Ordenar por:Orden:Resultados:

  • Corrigendum: A zebrafish model of Ifih1-driven Aicardi-Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients 
    Bernal-Bermudez, Beatriz; Martínez-López, Alicia; Martínez-Morcillo, Francisco-J; Tyrkalska, Sylwia-D; Martínez-Menchon, Teresa; Mesa-del-Castillo, Pablo; Cayuela, María-L; Mulero, Victoriano; García-Moreno, Diana (FRONTIERS MEDIA SA, 2023-11-24)
    BackgroundThe Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association ...
  • Development of a Short Telomere Zebrafish Model for Accelerated Aging Research and Antiaging Drug Screening 
    Hernández-Silva, David; López-Abellán, María-Dolores; Martínez-Navarro, Francisco-J; García-Castillo, Jesús; Cayuela-Fuentes, María-Luisa; Alcaraz-Pérez, Francisca (WILEY, 2025-06)
    Increased life expectancy is associated with a higher risk of age-related diseases, which represent a major public health challenge. Animal models play a crucial role in aging research, enabling the study of diseases at ...
  • Gaucher disease protects against tuberculosis 
    Fan, Jingwen; Hale, Victoria-L; Lelieveld, Lindsey-T; Whitworth, Laura-J; Busch-Nentwich, Elisabeth-M; Troll, Mark; Edelstein, Paul-H; Cox, Timothy-M; Roca, Francisco-J; Aerts, Johannes-MFG; Ramakrishnan, Lalita (NATL ACAD SCIENCES, 2023-02)
    Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease, characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in macrophages. Gaucher and other lysosomal diseases occur ...
  • Inflammation in Development and Aging: Insights from the Zebrafish Model 
    Mastrogiovanni, Marta; Martínez-Navarro, Francisco-Juan; Bowman, Teresa-V; Cayuela-Fuentes, María-Luisa (MDPI, 2024-02)
    Zebrafish are an emergent animal model to study human diseases due to their significant genetic similarity to humans, swift development, and genetic manipulability. Their utility extends to the exploration of the involvement ...
  • The Spike protein of SARS-CoV-2 signals via Tlr2 in zebrafish 
    Tyrkalska, Sylwia-D; Martínez-López, Alicia; Pedoto, Annamaria; Candel, Sergio; Cayuela-Fuentes, María-Luisa; Mulero, Victoriano (ELSEVIER SCI LTD, 2023-03)
    One of the most studied defense mechanisms against invading pathogens, including viruses, are Toll-like receptors (TLRs). Among them, TLR3, TLR7, TLR8 and TLR9 detect different forms of viral nucleic acids in endosomal ...