Repositorio Dspace

Listar por tema "Zebrafish"

Listar por tema "Zebrafish"

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  • A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia 
    Arriazu, Elena; Vicente, Carmen; Pippa, Raffaella; Peris, Irene; Martínez-Balsalobre, Elena; García-Ramírez, Patricia; Marcotegui, Nerea; Igea, Ana; Alignani, Diego; Rifon, José; Mateos, María-C; Cayuela, María-Luisa; Nebreda, Ángel-R; Odero, María-D (NATURE PUBLISHING GROUP, 2020-01-08)
    Acute myeloid leukemia (AML) is an aggressive hematologic malignancy. Although novel emerging drugs are available, the overall prognosis remains poor and new therapeutic approaches are required. PP2A phosphatase is a key ...
  • CDCA7 finely tunes cytoskeleton dynamics to promote lymphoma migration and invasion 
    Martín-Cortazar, Carla; Chiodo, Yuri; Jiménez-P, Raul; Bernabé, Manuel; Cayuela, María-Luisa; Iglesias, Teresa; Campanero, Miguel-R (FERRATA STORTI FOUNDATION, 2020-03-01)
    Metastases, the major cause of death from cancer, require cells' acquisition of the ability to migrate and involve multiple steps, including local tumor cell invasion and basement membrane penetration. Certain lymphoid ...
  • LacZ-reporter mapping of Dlx5/6 expression and genoarchitectural analysis of the postnatal mouse prethalamus 
    Puelles, Luis; Diaz, Carmen; Stuhmer, Thorsten; Ferran, José-L; Martínez-de-la-Torre, Margaret; Rubenstein, John-L-R (WILEY, 2021-02)
    We present here a thorough and complete analysis of mouse P0-P140 prethalamic histogenetic subdivisions and corresponding nuclear derivatives, in the context of local tract landmarks. The study used as fundamental material ...
  • New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells 
    Alburquerque-González, Begoña; Bernabé-García, Manuel; Montoro-García, Silvia; Bernabé-García, Ángel; Rodrigues, Priscila-Campioni; Ruiz-Sanz, Javier; López-Calderón, Fernando-F; Luque, Irene; Nicolas, Francisco-José; Cayuela, María-Luisa; Salo, Tuula; Pérez-Sánchez, Horacio; Conesa-Zamora, Pablo (SPRINGERNATURE, 2020-02)
    Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional colorectal carcinoma (CRC), and is characterized by frequent resistance to anti-epidermal growth factor receptor (EGFR) and overexpression ...