Repositorio Dspace

Listar por tema "T-Lymphocytes/metabolism"

Listar por tema "T-Lymphocytes/metabolism"

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  • Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output 
    Rodríguez-Fdez, Sonia; Citterio, Carmen; Francisco-Lorenzo-Martín, L; Baltanas-Copado, Jesús; Llorente-González, Clara; Corbalán-García, Senena; Vicente-Manzanares, Miguel; Bustelo, Xose-R (MDPI, 2019-12)
    Phosphatidylinositol-5 phosphate (PI5P) and other mono-phosphoinositides (mono-PIs) play second messenger roles in both physiological and pathological conditions. Despite this, their intracellular targets and mechanisms ...
  • Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease 
    Kim, Daehong; Park, Giljun; Huuhtanen, Jani; Lundgren, Sofie; Khajuria, Rajiv-K; Hurtado, Ana-María; Muñoz-Calleja, Cecilia; Cardeñoso, Laura; Gómez-García-de-Soria, Valle; Chen-Liang, Tzu-Hua; Eldfors, Samuli; Ellonen, Pekka; Hannula, Sari; Kankainen, Matti; Bruck, Oscar; Kreutzman, Anna; Salmenniemi, Urpu; Lonnberg, Tapio; Jerez-Cayuela, Andrés; Itala-Remes, Maija; Myllymaki, Mikko; Keranen, Mikko-A; Mustjoki, Satu (NATURE PORTFOLIO, 2020-05-07)
    Graft versus host disease (GvHD) is the main complication of allogeneic hematopoietic stem cell transplantation (HSCT). Here we report studies of a patient with chronic GvHD (cGvHD) carrying persistent CD4(+) T cell clonal ...