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Listar por tema "Mammals"

Listar por tema "Mammals"

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  • Adenylate kinase 9 is essential for sperm function and male fertility in mammals 
    O'Callaghan, Fiena; Navarrete-López, Paula; Stiavnicka, Miriama; Sánchez, José-M; Maroto, María; Pericuesta, Eva; Fernández-González, Raul; O'Meara, Ciara; Eivers, Bernard; Kelleher, Margaret-M; Evans, Ross-D; Mapel, Xena-M; Lioret-Villas, Audald; Pausch, Hubert; Balas (NATL ACAD SCIENCES, 2023-10-17)
    Despite passing routine laboratory tests for semen quality, bulls used in artificial insemination exhibit significant variation in fertility. Routine analysis of fertility data identified a dairy bull with extreme (10% ...
  • Effect of Superovulation Treatment on Oocyte's DNA Methylation 
    Lopes, Jordana-Sena; Ivanova, Elena; Ruiz, Salvador; Andrews, Simon; Kelsey, Gavin; Coy-Fuster, Pilar (MDPI, 2022-12)
    Controlled ovarian stimulation is a necessary step in some assisted reproductive procedures allowing a higher collection of female gametes. However, consequences of this stimulation for the gamete or the offspring have ...
  • Evolution of LPS recognition and signaling: The bony fish perspective 
    Martínez-López, Alicia; Tyrkalska, Sylwia-D; Alcaraz-Pérez, Francisca; Cabas, Isabel; Candel, Sergio; Martínez-Morcillo, Francisco-J; Sepulcre, María-P; García-Moreno, Diana; Cayuela-Fuentes, María-Luisa; Mulero, Victoriano (ELSEVIER SCI LTD, 2023-08)
    Fish are the most diverse and successful group of vertebrate animals, with about 30,000 species. The study of fish immunity is of great importance for understanding the evolution of vertebrate immunity, as they are the ...
  • Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality 
    Angosto-Bazarra, Diego; Alarcón-Vila, Cristina; Hurtado-Navarro, Laura; Baños, María-C; Rivers-Auty, Jack; Pelegrín, Pablo (BMC, 2022-01-07)
    BACKGROUND: Gasdermins are ancient (>500million-years-ago) proteins, constituting a family of pore-forming proteins that allow the release of intracellular content including proinflammatory cytokines. Despite their importance ...
  • Lectin-Binding Specificity of the Fertilization-Relevant Protein PDC-109 by Means of Surface Plasmon Resonance and Carbohydrate REcognition Domain EXcision-Mass Spectrometry 
    Defaus, Sira; Avilés, Manuel; Andreu, David; Gutiérrez-Gallego, Ricardo (MDPI, 2018-04)
    Seminal plasma proteins are relevant for sperm functionality and some appear responsible for establishing sperm interactions with the various environments along the female genital tract towards the oocyte. In recent years, ...
  • New Insights into the Mammalian Egg Zona Pellucida 
    Moros-Nicolás, Carla; Chevret, Pascale; Jiménez-Movilla, María; Algarra, Blanca; Cots-Rodríguez, Paula; González-Brusi, Leopoldo; Avilés, Manuel; Izquierdo-Rico, María-José (MDPI, 2021-03)
    Mammalian oocytes are surrounded by an extracellular coat called the zona pellucida (ZP), which, from an evolutionary point of view, is the most ancient of the coats that envelope vertebrate oocytes and conceptuses. This ...
  • Oviductin sets the species-specificity of the mammalian zona pellucida 
    de-la-Fuente, Daniel; Maroto, María; Cajas, Yulia-N; Canon-Beltran, Karina; Fernández-González, Raúl; Muñoz-Maceda, Ana; Sánchez-Puig, Juana-M; Blasco, Rafael; Cots-Rodríguez, Paula; Avilés, Manuel; Rizos, Dimitrios; Gutiérrez-Adan, Alfonso (eLIFE SCIENCES PUBL LTD, 2025-06-09)
    The zona pellucida (ZP) is vital for species-specific fertilization as this barrier mediates sperm-oocyte binding. Here, we determined whether sperm from distant mammalian orders (Carnivora, Primates, and Rodentia) could ...
  • Pan-retinal ganglion cell markers in mice, rats, and rhesus macaques 
    Nadal-Nicolás, Francisco-M; Galindo-Romero, Caridad; Lucas-Ruiz, Fernando; Marsh-Amstrong, Nicholas; Li, Wei; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta (SCIENCE PRESS, 2023-01-18)
    Univocal identification of retinal ganglion cells (RGCs) is an essential prerequisite for studying their degeneration and neuroprotection. Before the advent of phenotypic markers, RGCs were normally identified using ...
  • Peroxisome proliferator-activated receptors alpha and beta mediate the anti-inflammatory effects of the cyclopentenone prostaglandin 15-deoxy-?12,14-PGJ2 in fish granulocytes 
    Gómez-Abellán, Victoria; Pérez-Oliva, Ana-Belén; Cabas, Isabel; Hermi, Fatma; Arizcun, Marta; García-Moreno, Diana; Sepulcre, María-P; Mulero, Victoriano (ELSEVIER SCI LTD, 2022-11)
    Prostaglandins (PGs) are highly reactive small lipophilic molecules derived from polyunsaturated fatty acids of the cell membrane and play a key role in the resolution of inflammation processes. 15-deoxy-?(12,14)-PGJ(2) ...
  • The Terminal Segment of the Seminiferous Tubule: The Current Discovery of Its Morphofunctional Importance in Mammals 
    Seco-Rovira, Vicente; Beltrán-Frutos, Ester; Martínez-Hernández, Jesús; Madrid, Juan-Francisco; Pastor, Luis-Miguel (MDPI, 2025-02-18)
    The morphophysiology of intratesticular sperm pathways in mammals, including humans, is poorly understood. The seminiferous tubule is continuous with the straight tubule; however, its final portion-the terminal segment ...
  • TMEM95 is a sperm membrane protein essential for mammalian fertilization 
    Lamas-Toranzo, Ismael; Hamze, Julieta-G; Bianchi, Enrica; Fernández-Fuertes, Beatriz; Pérez-Cerezales, Serafín; Laguna-Barraza, Ricardo; Fernández-González, Raúl; Lonergan, Pat; Gutiérrez-Adan, Alfonso; Wright, Gavin-J; Jiménez-Movilla, María; Bermejo-Álvarez, Pablo (ELIFE SCIENCES PUBLICATIONS LTD, 2020)
    The fusion of gamete membranes during fertilization is an essential process for sexual reproduction. Despite its importance, only three proteins are known to be indispensable for sperm-egg membrane fusion: the sperm proteins ...