Repositorio Dspace

Listar por tema "Macrophages/metabolism"

Listar por tema "Macrophages/metabolism"

Ordenar por:Orden:Resultados:

  • Anti-inflammatory potential of digested Brassica sprout extracts in human macrophage-like HL-60 cells 
    García-Ibáñez, Paula; Núñez-Sánchez, María-Ángeles; Oliva-Bolarín, Alba; Martínez-Sánchez, María-A; Ramos-Molina, Bruno; Ruiz-Alcaraz, Antonio-José; Moreno, Diego-A (ROYAL SOC CHEMISTRY, 2023-01-03)
    Cruciferous vegetables have been reported to be a great source of anti-inflammatory compounds. Specifically, sprouts from the Brassicaceae family stand out for their high content of glucosinolates (and their bioactive ...
  • Danger signals released during cold ischemia storage activate NLRP3 inflammasome in myeloid cells and influence early allograft function in liver transplantation 
    Lucas-Ruiz, Fernando; Mateo, Sandra; Jover-Aguilar, Marta; Alconchel-Gago, Felipe; Martínez-Alarcón, Laura; de-Torre-Minguela, Carlos; Vidal-Correoso, Daniel; Villalba-López, Francisco; López-López, Víctor; Ríos-Zambudio, Antonio; Pons-Miñano, José-Antonio; Ramírez, Pablo; Pelegrín, Pablo; Baroja-Mazo, Alberto (ELSEVIER, 2023-01)
    BACKGROUND: Innate immunity plays a fundamental role in solid organ transplantation. Myeloid cells can sense danger signals or DAMPs released after tissue or cell damage, such as during ischemia processes. This study aimed ...
  • Exploring association of melanoma-specific Bcl-xL with tumor immune microenvironment 
    Lucíano, Anna-María; Di-Martile, Marta; Pérez-Oliva, Ana-Belén; Di-Caprio, Marica; Foddai, María-Laura; Buglioni, Simonetta; Mulero, Victoriano; del-Bufalo, Donatella (BMC, 2023-07)
    BACKGROUND: Macrophages take center stage in the tumor microenvironment, a niche composed of extracellular matrix and a heterogeneous group of cells, including immune ones. They can evolve during tumor progression and ...
  • Exploring mechanisms of scar-free skin wound healing in adult zebrafish in comparison to mouse 
    Kucukaylak, Ismail; Halwas, Kai; Martínez-Morcillo, Francisco-Javier; Reiche, Nils; Metzger, Manuel; Comelli, Petra; Voigt, Birgit; Brinckmann, Jurgen; Eming, Sabine; Hammerschmidt, Matthias (PUBLIC LIBRARY SCIENCE, 2026-06-24)
    Adult zebrafish have the ability to perfectly regenerate their skin after injury without leaving a scar behind. Yet, they intermediately form a collagen-rich granulation tissue that later fully regresses. In contrast, adult ...
  • Gasdermin E mediates pyroptotic cell death of neutrophils and macrophages in a zebrafish model of chronic skin inflammation 
    Lozano-Gil, Juan-M; Rodríguez-Ruiz, Lola; Tyrkalska, Sylwia-D; García-Moreno, Diana; Pérez-Oliva, Ana-Belén; Mulero, Victoriano (ELSEVIER SCI LTD, 2022-07)
    Chronic diseases and hematopoietic disorders are associated with dysregulation of the inflammasome. Our group has recently reported the relevance of the inflammasome in the differentiation of hematopoietic stem and progenitor ...
  • Gasdermins mediate cellular release of mitochondrial DNA during pyroptosis and apoptosis 
    de-Torre-Minguela, Carlos; Gómez, Ana-I; Couillin, Isabelle; Pelegrín, Pablo (WILEY, 2021-08)
    Pyroptosis and intrinsic apoptosis are two forms of regulated cell death driven by active caspases where plasma membrane permeabilization is induced by gasdermin pores. Caspase-1 induces gasdermin D pore formation during ...
  • The total electric charge and time of application of galvanic currents to macrophages can optimize the release of IL-1ß with low cell death 
    Penin-Franch, Alejandro; García-Vidal, José-Antonio; Gómez, Ana-Isabel; Escolar-Reina, Pilar; Medina-Mirapeix, Francesc; Pelegrín, Pablo (NATURE PORTFOLIO, 2024-12-28)
    Galvanic current has been emerging as a novel therapy to regenerate chronic tissue lesions, including musculoskeletal and dermatological lesions. Recently, the NLRP3 inflammasome and IL-1? release have been identified as ...
  • USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation 
    Palazon-Riquelme, Pablo; Worboys, Jonathan-D; Green, Jack; Valera, Ana; Martín-Sánchez, Fatima; Pellegrini, Carolina; Brough, David; López-Castejón, Gloria (WILEY, 2018-10)
    The assembly and activation of the inflammasomes are tightly regulated by post-translational modifications, including ubiquitin. Deubiquitinases (DUBs) counteract the addition of ubiquitin and are essential regulators of ...
  • von Willebrand factor links primary hemostasis to innate immunity 
    Drakeford, Clive; Águila, Sonia; Roche, Fiona; Hokamp, Karsten; Fazavana, Judicael; Cervantes, Mariana-P; Curtis, Annie-M; Hawerkamp, Heike-C; Dhami, Sukhraj-Pal-Singh; Charles-Messance, Hugo; Hackett, Emer-E; Chion, Alain; Ward, Soracha; Ahmad, Azaz; Schoen, Ingmar; Breen, Eamon; Keane, Joe; Murphy, Ross; Preston, Roger-JS; O'Sullivan, Jamie-M; Sheedy, Frederick-J; Fallon, Padraic; O'Donnell, James-S (NATURE PORTFOLIO, 2022-11)
    The plasma multimeric glycoprotein von Willebrand factor (VWF) plays a critical role in primary hemostasis by tethering platelets to exposed collagen at sites of vascular injury. Recent studies have identified additional ...