Repositorio Dspace

Listar por tema "K562 Cells"

Listar por tema "K562 Cells"

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  • CD33 (Siglec-3) Inhibitory Function: Role in the NKG2D/DAP10 Activating Pathway 
    Hernández-Caselles, Trinidad; Corral-San-Miguel, Rubén; Ruiz-Alcaraz, Antonio-José; García-Peñarrubia, Pilar (HINDAWI LTD, 2019)
    CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid subsets, including NK cells. It may constitute a control mechanism ...
  • TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome 
    Lozano-Gil, Juan-Manuel; Rodríguez-Ruiz, Lola; Palacios, Manuel; Peral, Jorge; Navarro, Susana; Fuster-Soler, José-Luis; Beléndez, Cristina; Jérez-Cayuela, Andrés; Murillo-Sanjuan, Laura; Díaz-de-Heredia, Cristina; López-de-Hontanar, Guzmán; Zubicaray, Josune; Sevilla, Julián; Ferrer-Marín, Francisca; Sepulcre-Cortés, María-Pilar; Cayuela-Fuentes, María-Luisa; García-Moreno, Diana; Martínez-López, Alicia; Tyrkalska, Sylwia-D; Mulero, Victoriano (SPRINGERNATURE, 2026-01-09)
    Diamond-Blackfan anemia syndrome (DBAS) is marked by defective erythropoiesis caused by impaired ribosome biogenesis and aberrant signaling. Here, we investigate how ribosomal stress-induced activation of the NLRP1 ...