Repositorio Dspace

Listar por tema "B-Lymphocytes"

Listar por tema "B-Lymphocytes"

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  • A novel and efficient tandem CD19-and CD22-directed CAR for B cell ALL 
    Zanetti,Samanta-Romina; Velasco-Hernandez,Talia; Gutierrez-Aguera,Francisco; Diaz,Victor-M; Romecin,Paola-Alejandra; Roca-Ho,Heleia; Sanchez-Martinez,Diego; Tirado,Nestor; Baroni,Matteo-Libero; Petazzi,Paolo; Torres-Ruiz,Raul; Molina,Oscar; Bataller,Alex| (CELL PRESS, 02/02/2022)
    CD19-directed chimeric antigen receptor (CAR) T cells have yielded impressive response rates in refractory/relapse B cell acute lymphoblastic leukemia (B-ALL); however, most patients ultimately relapse due to poor CAR T ...
  • High-risk subtypes of chronic lymphocytic leukemia are detectable as early as 16 years prior to diagnosis 
    Kolijn, PMartijn; Hosnijeh, Fatemeh-Saberi; Spath, Florentin; Hengeveld, Paul-J; Agathangelidis, Andreas; Saleh, Manal; Casabonne, Delphine; Benavente, Yolanda; Jerkeman, Mats; Agudo, Antonio; Barricarte, Aurelio; Besson, Caroline; Sánchez, María-José; Chirlaque-López, María-Dolores; Masala, Giovanna; Sacerdote, Carlotta; Grioni, Sara; Schulze, Matthias-B; Nieters, Alexandra; Engelfriet, Peter; Hultdin, Magnus; McKay, James-D; Vermeulen, Roel-CH; Langerak, Anton-W (AMER SOC HEMATOLOGY, 2022-03)
    Chronic lymphocytic leukemia (CLL) is preceded by monoclonal B-cell lymphocytosis (MBL), a CLL precursor state with a prevalence of up to 12% in aged individuals; however, the duration of MBL and the mechanisms of its ...
  • Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes 
    Aterido, Adria; López-Lasanta, María; Blanco, Francisco; Juan-Mas, Antonio; García-Vivar, María-Luz; Erra, Alba; Pérez-García, Carolina; Sánchez-Fernández, Simon-Angel; Sanmarti, Raimon; Fernández-Nebro, Antonio; Alperi-López, Mercedes; Tornero, Jesus; Ortiz, Ana-María; Fernández-Cid, Carlos-Marras; Palau, Nuria; Pan, Wenjing; Byrne-Steele, Miranda; Starenki, Dmytro; Weber, Daniel; Rodríguez-Nunez, Ivan; Han, Jian; Myers, Richard-M; Marsal, Sara; Julia, Antonio (BMC, 2024-03)
    BACKGROUND: In rheumatoid arthritis (RA), the activation of T and B cell clones specific for self-antigens leads to the chronic inflammation of the synovium. Here, we perform an in-depth quantitative analysis of the seven ...