Repositorio Dspace

Listar por autor "de-Torre-Minguela, Carlos"

Listar por autor "de-Torre-Minguela, Carlos"

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  • CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis 
    Alarcón-Vila, Cristina; Baroja-Mazo, Alberto; de-Torre-Minguela, Carlos; Martínez, Carlos-M; Martínez-García, Juan-José; Martínez-Banaclocha, Helios; García-Palenciano, Carlos; Pelegrín, Pablo (ELIFE SCIENCES PUBLICATIONS LTD, 2020-11)
    P2X7 receptor activation induces the release of different cellular proteins, such as CD14, a glycosylphosphatidylinositol (GPI)-anchored protein to the plasma membrane important for LPS signaling via TLR4. Circulating CD14 ...
  • Danger signals released during cold ischemia storage activate NLRP3 inflammasome in myeloid cells and influence early allograft function in liver transplantation 
    Lucas-Ruiz, Fernando; Mateo, Sandra; Jover-Aguilar, Marta; Alconchel-Gago, Felipe; Martínez-Alarcón, Laura; de-Torre-Minguela, Carlos; Vidal-Correoso, Daniel; Villalba-López, Francisco; López-López, Víctor; Ríos-Zambudio, Antonio; Pons-Miñano, José-Antonio; Ramírez, Pablo; Pelegrín, Pablo; Baroja-Mazo, Alberto (ELSEVIER, 2023-01)
    BACKGROUND: Innate immunity plays a fundamental role in solid organ transplantation. Myeloid cells can sense danger signals or DAMPs released after tissue or cell damage, such as during ischemia processes. This study aimed ...
  • Gasdermins mediate cellular release of mitochondrial DNA during pyroptosis and apoptosis 
    de-Torre-Minguela, Carlos; Gómez, Ana-I; Couillin, Isabelle; Pelegrín, Pablo (WILEY, 2021-08)
    Pyroptosis and intrinsic apoptosis are two forms of regulated cell death driven by active caspases where plasma membrane permeabilization is induced by gasdermin pores. Caspase-1 induces gasdermin D pore formation during ...
  • Melanoma. Guía clínica práctica 
    Chirlaque-López, María-Dolores; Campillo-Fuentes, Juana; Campillo-Marquina, José-Antonio; Carrasco-Martínez, María-Angeles; Cerezuela-Fuentes, Pablo; Contreras-Gutiérrez, José-Fulgencio; Corbalán-Vélez, Raúl; de-Torre-Minguela, Carlos; Escolar-Pérez, Pedro-Pablo; Frías-Iniesta, José-Francisco; Gómez-Colldefors, María-Carmen; López-Ávila, Ángel; Macías-Cerrolaza, José-Antonio; Martín-Rodríguez, Ana; Martínez-Barba, Enrique; Martínez-Escribano, Jorge; Martínez-Menchón, Teresa; Minguela-Puras, Alfredo; Navarro-Sánchez, Carmen; Nicolás-Ruiz, Francisco; Ortiz-Reina, Sebastián; Pagán-Muñoz, Inmaculada; Pereda-Carrasco, Carolina; Piñero-Madrona, Antonio; Poblet-Martínez, Enrique; Porras-Martínez, Mariano; Ramírez-Andreo, Antonio; Rodríguez-González, José-Manuel; Ros-Martínez, Silverio; Soria-Martínez, María-Caridad (2016)
  • Metabolomics study of the formation of genotoxic molecules based on the fecal volatile metabolites profile using an in vivo animal model 
    Giménez-Campillo, Claudia; Campillo, Natalia; Arroyo-Manzanares, Natalia; Martínez, Carlos-M; de-Torre-Minguela, Carlos; Viñas, Pilar (ELSEVIER, 2024-04)
  • P2X7 receptor induces Tumor necrosis Factor-a converting enzyme activation and release to Boost TnF-ae Production 
    Barberá-Cremades, María; Gómez, Ana-I; Baroja-Mazo, Alberto; Martínez-Alarcón, Laura; Martínez, Carlos-M; de-Torre-Minguela, Carlos; Pelegrín, Pablo (FRONTIERS MEDIA SA, 2017-07-24)
    Tumor necrosis factor (TNF)-? is a major pro-inflammatory cytokine produced in response to toll-like receptor stimulation. TNF-? release is controlled by the activity of TNF-? converting enzyme (TACE) that cut membrane-bound ...
  • Profiling Human CD55 Transgene Performance Assist in Selecting Best Suited Specimens and Tissues for Swine Organ Xenotransplantation 
    Martínez-Alarcón, Laura; Liarte, Sergio; Quereda, Juan-J; Saez-Acosta, Aida; de-Torre-Minguela, Carlos; Mendonca, Livia; Abelláneda, Juana-M; Majado, María-J; Rios-Zambudio, Antonio; Ramírez, Pablo; Muñoz, Antonio; Ramis-Vidal, Guillermo (MDPI, 2021-08)
    Xenotransplantation of pig organs receives substantial attention for being comparable to human's. However, compatibility constraints involving hyper-acute rejection (HAR) still block clinical applications. Transgenesis of ...
  • Proteomics in Liver Transplantation: A Systematic Review 
    López-López, Víctor; Pérez-Sanz, Fernando; de-Torre-Minguela, Carlos; Marco-Abenza, Josefa; Robles-Campos, Ricardo; Sánchez-Bueno, Francisco; Pons-Miñano, José-Antonio; Ramírez, Pablo; Baroja-Mazo, Alberto (FRONTIERS MEDIA SA, 2021-07)
    BACKGROUND: Although proteomics has been employed in the study of several models of liver injury, proteomic methods have only recently been applied not only to biomarker discovery and validation but also to improve ...
  • The NLRP3 and Pyrin Inflammasomes: Implications in the Pathophysiology of Autoinflammatory Diseases 
    de-Torre-Minguela, Carlos; Mesa-del-Castillo, Pablo; Pelegrín, Pablo (FRONTIERS MEDIA SA, 2017-01-27)
    Inflammasomes are multiprotein complexes that critically control different aspects of innate and adaptive immunity. Among them we could highlight the release of pro-inflammatory cytokines that induce and maintain the ...