Repositorio Dspace

Listar por autor "Lachaud, Christophe"

Listar por autor "Lachaud, Christophe"

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  • UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival 
    Lee, Lara; Pérez-Oliva, Ana-Belén; Martínez-Balsalobre, Elena; Churikov, Dmitri; Peter, Joshua; Rahmouni, Dalicya; Audoly, Gilles; Azzoni, Violette; Audebert, Stephane; Camoin, Luc; Mulero, Victoriano; Cayuela-Fuentes, María-Luisa; Kulathu, Yogesh; Geli, Vincent; Lachaud, Christophe (AMER ASSOC ADVANCEMENT SCIENCE, 2021-09)
    Ubiquitin-fold modifier 1 (UFM1) is involved in neural and erythroid development, yet its biological roles in these processes are unknown. Here, we generated zebrafish models deficient in Ufm1 and Ufl1 that exhibited ...
  • ZAKa/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome 
    Rodríguez-Ruiz, Lola; Lozano-Gil, Juan-M; Naranjo-Sánchez, Elena; Martínez-Balsalobre, Elena; Martínez-López, Alicia; Lachaud, Christophe; Blanquer-Blanquer, Miguel; Phung, Toan-K; García-Moreno, Diana; Cayuela, María-L; Tyrkalska, Sylwia-D; Pérez-Oliva, Ana-Belén; Mulero, Victoriano (SPRINGERNATURE, 2023-10)
    Chronic inflammatory diseases are associated with hematopoietic lineage bias, including neutrophilia and anemia. We have recently identified that the canonical inflammasome mediates the cleavage of the master erythroid ...