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  • XAF1 as a modifier of p53 function and cancer susceptibility 
    Pinto, Emilia-M; Figueiredo, Bonald-C; Chen, Wenan; Galvao, Henrique-CR; Formiga, María-Nirvana; Fragoso, María-Candida-B; Ashton-Prolla, Patricia; Ribeiro, Enilze-MSF; Felix, Gabriela; Costa, Tatiana-EB; Savage, Sharon-A; Yeager, Meredith; Palmero, Edenir; Volc, Sahlua; Salvador, Héctor; Fuster-Soler, José-Luis; Lavarino, Cinzia; Chantada, Guillermo; Vaur, Dominique; Odone-Filho, Vicente; Brugieres, Laurence; Else, Tobias; Stoffel, Elena-M; Maxwell, Kara-N; Achatz, María-Isabel; Kowalski, Luis; de-Andrade, Kelvin-C; Pappo, Alberto; Letouze, Eric; Latronico, Ana-Claudia; Mendonca, Berenice-B; Almeida, Madson-Q; Brondani, Vania-B; Bittar, Camila-M; Soares, Emerson-WS; Mathias, Carolina; Ramos, Cintia-RN; Machado, Moara; Zhou, Weiyin; Jones, Kristine; Vogt, Aurelie; Klincha, Payal-P; Santiago, Karina-M; Komechen, Heloisa; Paraizo, Mariana-M; Parise, Ivy-ZS; Hamilton, Kayla; Wang, Jinling; Rampersaud, Evadnie; Clay, Michael-R; Murphy, Andrew-J; Lalli, Enzo; Nichols, Kim-E; Ribeiro, Raúl-C; Rodríguez-Galindo, Carlos; Korbonits, Marta; Zhang, Jinghui; Thomas, Mark-G; Connelly, Jon-P; Pruett-Miller, Shondra; Diekmann, Yoan; Neale, Geoffrey; Wu, Gang; Zambetti, Gerard-P (AMER ASSOC ADVANCEMENT SCIENCE, 2020-06)
    Cancer risk is highly variable in carriers of the common TP53-R337H founder allele, possibly due to the influence of modifier genes. Whole-genome sequencing identified a variant in the tumor suppressor XAF1 (E134/Glu134T ...
  • XIII Congreso Nacional de Hospitales: comunicaciones orales, ponencias y posters presentadas por personas y organismos de la Región de Murcia 
    Consejería de Sanidad (Consejería de Sanidad, 2003)
  • XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (I) 
    Fernández, Óscar; Ares, Adrián; Agüera, Eduardo; Aladro, Yolanda; Alonso, Ana; Arroyo, Rafael; Brieva, Luis; Calles, Carmen; Caminero, Ana-Belén; Castillo-Trivino, Tamara; Costa-Frossard, Lucienne; Eichau, Sara; Hernández, Miguel-Ángel; Landete, Lamberto; Llaneza, Miguel; Llufriu, Sara; Meca-Lallana, José-Eustasio; Meca-Lallana, Virginia; Moral, Ester; Oreja-Guevara, Celia; Prieto, José-María; Romero-Pinel, Lucía; Vilaseca, Andreu; Rodríguez-Antiguedad, Alfredo (IMR PRESS, 2026-01-21)
    Introduction: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists ...
  • XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (II) 
    Fernández, Óscar; Ares, Adrián; Agüera, Eduardo; Aladro, Yolanda; Alonso, Ana; Arroyo, Rafael; Brieva, Luis; Calles, Carmen; Caminero, Ana-Belén; Castillo-Trivino, Tamara; Costa-Frossard, Lucienne; Eichau, Sara; Hernández, Miguel-Ángel; Landete, Lamberto; Llaneza, Miguel; Llufriu, Sara; Meca-Lallana, José-Eustasio; Meca-Lallana, Virginia; Moral, Ester; Oreja-Guevara, Celia; Prieto, José-María; Romero-Pinel, Lucía; Vilaseca, Andreu; Rodríguez-Antiguedad, Alfredo (IMR PRESS, 2026-01-21)
    Introduction: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists ...
  • Y parirás a tus hijos... sin dolor 
    Ramón-Esparza, Teresa; Parra-Hidalgo, Pedro; Nieto-Martínez, Pilar; Calle-Urra, José-Eduardo; Arellano-Morata, Carmen (2012)
  • Y Prospective analysis of circulating metabolites and endometrial cancer risk 
    Dossus, Laure; Kouloura, Eirini; Biessy, Carine; Viallon, Vivian; Siskos, Alexandros-P; Dimou, Niki; Rinaldi, Sabina; Merritt, Melissa-A; Allen, Naomi; Fortner, Renee-T; Kaaks, Rudolf; Weiderpass, Elisabete; Gram, Inger-Torhild; Rothwell, Joseph-A; Lecuyer, Lucie; Severi, Gianluca; Schulze, Matthias-B; Nost, Therese-Haugdahl; Crous-Bou, Marta; Sánchez, María-José; Amiano, Pilar; Colorado-Yohar, Sandra-Milena; Barricarte-Gurrea, Aurelio; Schmidt, Julie-A; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Vermeulen, Roel; Heath, Alicia-K; Christakoud, Sofía; Tsilidis, Konstantinos-K; Travis, Ruth-C; Gunter, Marc-J; Keun, Hector-C (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2021-08)
    BACKGROUND: Endometrial cancer is strongly associated with obesity and dysregulation of metabolic factors such as estrogen and insulin signaling are causal risk factors for this malignancy. To identify additional novel ...
  • ¿Y si la oxigenoterapia de alto flujo no es el tratamiento idóneo para la bronquiolitis en las plantas de hospitalización? 
    Reyes-Domínguez, Susana-Beatriz; del-Villar-Guerra, Pablo; Oñate-Vergara, Eider; Miñambres-Rodríguez, María (Elsevier Doyma, 2020)
  • Year-Long Phenotypical Study of Calves Derived From Different Assisted-Reproduction Technologies 
    Lopes, Jordana-Sena; Soriano-Úbeda, Cristina; Paris-Oller, Evelyne; Navarro-Serna, Sergio; Canha-Gouveia, Analuce; Sarrias-Gil, Lucía; Cerón, José-Joaquín; Coy-Fuster, Pilar (FRONTIERS MEDIA SA, 2022-01-10)
    Assisted reproductive technologies play a major role in the cattle industry. An increase in the use of in vitro-derived embryos is currently being seen around the globe. But the efficiency and quality of the in vitro-derived ...
  • ZAKa/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome 
    Rodríguez-Ruiz, Lola; Lozano-Gil, Juan-M; Naranjo-Sánchez, Elena; Martínez-Balsalobre, Elena; Martínez-López, Alicia; Lachaud, Christophe; Blanquer-Blanquer, Miguel; Phung, Toan-K; García-Moreno, Diana; Cayuela, María-L; Tyrkalska, Sylwia-D; Pérez-Oliva, Ana-Belén; Mulero, Victoriano (SPRINGERNATURE, 2023-10)
    Chronic inflammatory diseases are associated with hematopoietic lineage bias, including neutrophilia and anemia. We have recently identified that the canonical inflammasome mediates the cleavage of the master erythroid ...
  • Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes 
    García-Valtanen, Pablo; Martínez-López, Alicia; López-Muñoz, Azucena; Bello-Pérez, Melissa; Medina-Gali, Regla-M; Ortega-Villaizan, María-del-Mar; Varela, Mónica; Figueras, Antonio; Mulero, Victoriano; Novoa, Beatriz; Estepa, Amparo; Coll, Julio (FRONTIERS MEDIA SA, 2017-02-13)
    To investigate fish innate immunity, we have conducted organ and cell immune-related transcriptomic as well as immunohistologic analysis in mutant zebra fish (Danio rerio) lacking adaptive immunity (rag1(-/-)) at different ...
  • Zebra Fish Lacking Adaptive immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene expression of Apoptosis, Multigene Families, and interferon-related Genes (vol 8, pg 121, 2017) 
    García-Valtanen, Pablo; Martínez-López, Alicia; López-Muñoz, Azucena; Bello-Pérez, Melissa; Medina-Gali, Regla-M; Ortega-Villaizan, María-del-Mar; Varela, Mónica; Figueras, Antonio; Mulero, Victoriano; Novoa, Beatriz; Estepa, Amparo; Coll, Julio (FRONTIERS MEDIA SA, 2017-06-13)
    [This corrects the article on p. 121 in vol. 8, PMID: 28243233.].
  • Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment 
    Gómez-Abenza, Elena; Ibañez-Molero, Sofia; García-Morenou, Diana; Fuentes, Inmaculada; Zon, Leonard; Mione, María-C; Cayuela-Fuentes, María-Luisa; Gabellini, Chiara; Mulero, Victoriano (BMC, 2019-09-13)
    BACKGROUND: Skin cutaneous melanoma (SKCM) is the most lethal form of skin cancer and while incidence rates are declining for most cancers, they have been steadily rising for SKCM. Serine protease inhibitor, kunitz-type, ...
  • Zebrafish models of COVID-19 
    Tyrkalska, Sylwia-D; Candel, Sergio; Pedoto, Annamaria; García-Moreno, Diana; Alcaraz-Pérez, Francisca; Sánchez-Ferrer, Álvaro; Cayuela-Fuentes, María-Luisa; Mulero, Victoriano (OXFORD UNIV PRESS, 2023-01-16)
    Although COVID-19 has only recently appeared, research studies have already developed and implemented many animal models for deciphering the secrets of the disease and provided insights into the biology of SARS-CoV-2. ...
  • Zebrafish Models to Study the Crosstalk between Inflammation and NADPH Oxidase-Derived Oxidative Stress in Melanoma 
    Pardo-Sánchez, Irene; García-Moreno, Diana; Mulero, Victoriano (MDPI, 2022-07)
    Melanoma is the deadliest form of skin cancer, and its incidence continues to increase. In the early stages of melanoma, when the malignant cells have not spread to lymph nodes, they can be removed by simple surgery and ...
  • Zinc concentration in preterm newborns at term age, a prospective observational study 
    Vázquez-Gomis, Rosmari; Bosch-Giménez, Vicente; Juste-Ruiz, Mercedes; Vázquez-Gomis, Consuelo; Izquierdo-Fos, Ignacio; Pastor-Rosado, Jose (BMJ PUBLISHING GROUP, 2019-06)
    OBJECTIVES: To determine zinc concentrations and associated factors in a population of preterm newborns at term age. DESIGN: This analytical, descriptive, observational and prospective study was conducted in the neonatal ...
  • Zirconia implants and peek restorations for the replacement of upper molars 
    Parmigiani-Izquierdo, José-María; Cabana-Muñoz, María-Eugenia; Merino, Jose-Joaquín; Sánchez-Pérez, Arturo (SPRINGER JAPAN KK, 2017-02-20)
    BACKGROUND: One of the disadvantages of the zirconia implants is the lack of elasticity, which is increased with the use of ceramic or zirconia crowns. The consequences that could result from this lack of elasticity have ...
  • Zn-containing Adhesives Facilitate Collagen Protection and Remineralization at the Resin-Dentin Interface: A Narrative Review 
    Toledano, Manuel; Toledano-Osorio, Manuel; Hannig, Matthias; Carrasco-Carmona, Álvaro; Osorio, María-T; García-Godoy, Franklin; Cabello, Inmaculada; Osorio, Raquel (MDPI, 2022-02)
    This is a narrative review of the literature assessing the potential effectiveness of doping dentin polymeric adhesives with zinc compounds in order to improve bonding efficacy, remineralization and protection against ...
  • Zona habilitada para fumar. Uso exclusivo para las personas internas 
    Consejería de Sanidad y Consumo. Dirección General de Salud Pública (Consejería de Sanidad y Consumo, 2010)
  • ZP4 confers structural properties to the zona pellucida essential for embryo development 
    Lamas-Toranzo, Ismael; Fonseca-Balvis, Noelia; Querejeta-Fernández, Ana; Izquierdo-Rico, María-José; González-Brusi, Leopoldo; Lorenzo, Pedro-L; García-Rebollar, Pilar; Avilés, Manuel; Bermejo-Álvarez, Pablo (ELIFE SCIENCES PUBLICATIONS LTD, 2019-10-22)
    Zona pellucida (ZP), the extracellular matrix sheltering mammalian oocytes and embryos, is composed by 3 to 4 proteins. The roles of the three proteins present in mice have been elucidated by KO models, but the function ...
  • ZP4 Is Present in Murine Zona Pellucida and Is Not Responsible for the Specific Gamete Interaction 
    Izquierdo-Rico, María-José; Moros-Nicolás, Carla; Pérez-Crespo, Miriam; Laguna-Barraza, Ricardo; Gutiérrez-Adan, Alfonso; Veyrunes, Frederic; Ballesta, José; Laudet, Vincent; Chevret, Pascale; Avilés, Manuel (FRONTIERS MEDIA SA, 2021-01-18)
    Mammalian eggs are surrounded by an extracellular matrix called the zona pellucida (ZP). This envelope participates in processes such as acrosome reaction induction, sperm binding, protection of the oviductal embryo, and ...