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Listar02.06.01. Investigación y comunicación científica por tema "Zebrafish"

Listar02.06.01. Investigación y comunicación científica por tema "Zebrafish"

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  • Suramin, a drug for the treatment of trypanosomiasis, reduces the prothrombotic and metastatic phenotypes of colorectal cancer cells by inhibiting hepsin 
    Zaragoza-Huesca, David; Ródenas, María-del-Carmen; Penas-Martínez, Julia; Pardo-Sánchez, Irene; Pena-García, Jorge; Espín, Salvador; Ricote, Guillermo; Nieto, Andrés; García-Molina, Francisco; Vicente, Vicente; Lozano, María-Luisa; Carmona-Bayonas, Alberto; Mulero, Victoriano; Pérez-Sánchez, Horacio; Martínez-Martínez, Irene (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2023-12)
    Recently, our group identified serine-protease hepsin from primary tumor as a biomarker of metastasis and thrombosis in patients with localized colorectal cancer. We described hepsin promotes invasion and thrombin generation ...
  • TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome 
    Lozano-Gil, Juan-Manuel; Rodríguez-Ruiz, Lola; Palacios, Manuel; Peral, Jorge; Navarro, Susana; Fuster-Soler, José-Luis; Beléndez, Cristina; Jérez-Cayuela, Andrés; Murillo-Sanjuan, Laura; Díaz-de-Heredia, Cristina; López-de-Hontanar, Guzmán; Zubicaray, Josune; Sevilla, Julián; Ferrer-Marín, Francisca; Sepulcre-Cortés, María-Pilar; Cayuela-Fuentes, María-Luisa; García-Moreno, Diana; Martínez-López, Alicia; Tyrkalska, Sylwia-D; Mulero, Victoriano (SPRINGERNATURE, 2026-01-09)
    Diamond-Blackfan anemia syndrome (DBAS) is marked by defective erythropoiesis caused by impaired ribosome biogenesis and aberrant signaling. Here, we investigate how ribosomal stress-induced activation of the NLRP1 ...

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