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Listar 02.01.01. Investigación y comunicación científica por título

Listar 02.01.01. Investigación y comunicación científica por título

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  • Targeting protein methylation in pancreatic cancer cells results in KRAS signaling imbalance and inhibition of autophagy 
    Montenegro, María-F; Marti-Diaz, Roman; Navarro, Ana; Tolivia, Jorge; Sánchez-del-Campo, Luis; Cabezas-Herrera, Juan; Rodríguez-López, José-Neptuno (SPRINGERNATURE, 2023-11)
    Pancreatic cancer cells with mutant KRAS require strong basal autophagy for viability and growth. Here, we observed that some processes that allow the maintenance of basal autophagy in pancreatic cancer cells are controlled ...
  • Taurine: an essential amino sulfonic acid for retinal health 
    Di-Pierdomenico, Johnny; Martínez-Vacas, Ana; Picaud, Serge; Villegas-Pérez, María-Paz; García-Ayuso, Diego- (Wolters Kluwer Medknow Publications, 2023)
  • Techniques to Study Inflammasome Activation and Inhibition by Small Molecules 
    Angosto-Bazarra, Diego; Molina-López, Cristina; Penin-Franch, Alejandro; Hurtado-Navarro, Laura; Pelegrín, Pablo (MDPI, 2021-03)
    Inflammasomes are immune cytosolic oligomers involved in the initiation and progression of multiple pathologies and diseases. The tight regulation of these immune sensors is necessary to control an optimal inflammatory ...
  • Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness 
    Bernabe-García, Manuel; Martínez-Balsalobre, Elena; García-Moreno, Diana; García-Castillo, Jesús; Revilla-Nuin, Beatriz; Blanco-Alcaina, Elena; Mulero, Victoriano; Alcaraz-Pérez, Francisca; Cayuela, María-L (Wiley, 2021-07)
    Telomerase reverse transcriptase (TERT) maintains telomere homeostasis, thus ensuring chromosome stability and cell proliferation. In addition, several telomere-independent functions of human TERT have been described. In ...
  • Telomerase RNA-based aptamers restore defective myelopoiesis in congenital neutropenic syndromes 
    Martínez-Balsalobre, Elena; García-Castillo, Jesús; García-Moreno, Diana; Naranjo-Sánchez, Elena; Fernández-Lajarin, Miriam; Blasco, María-A; Alcaraz-Pérez, Francisca; Mulero, Víctoriano; Cayuela, María-L (NATURE PORTFOLIO, 2023-09)
    Telomerase RNA (TERC) has a noncanonical function in myelopoiesis binding to a consensus DNA binding sequence and attracting RNA polymerase II (RNA Pol II), thus facilitating myeloid gene expression. The CR4/CR5 domain of ...
  • The Accuracy and Absolute Reliability of a Knee Surgery Assistance System Based on ArUco-Type Sensors 
    Leon-Muñoz, Vicente-J; Santonja-Medina, Fernando; Lajara-Marco, Francisco; Lison-Almagro, Alonso-J; Jiménez-Olivares, Jesús; Marín-Martínez, Carmelo; Amor-Jiménez, Salvador; Galian-Muñoz, Elena; López-López, Mirian; Moya-Ángeler, Joaquín (MDPI, 2023-10)
    Recent advances allow the use of Augmented Reality (AR) for many medical procedures. AR via optical navigators to aid various knee surgery techniques (e.g., femoral and tibial osteotomies, ligament reconstructions or menisci ...
  • The Application of a System of Eye Tracking in Laparoscopic Surgery: A New Didactic Tool to Visual Instructions 
    Marín-Conesa, Ester; Sánchez-Ferrer, Francisco; Grima-Murcia, María-Dolores; Sánchez-Ferrer, María-Luisa (FRONTIERS MEDIA SA, 2021-06)
    Introduction: Laparoscopic surgery is an increasingly used technique, but it requires a high degree of learning, and communication between the operating room crew is considerably difficult. The use of eye tracking has been ...
  • The aptamer BT200 blocks interaction of K1405-K1408 in the VWF-A1 domain with macrophage LRP1 
    Chion, Alain; Byrne, Ciara; Atiq, Ferdows; Doherty, Dearbhla; Aguila, Sonia; Fazavana, Judicael; Lopes, Patricia; Karampini, Ellie; Amin, Aamir; Preston, Roger-JS; Baker, Ross-I; Mckinnon, Thomas-AJ; Zhu, Shuhao; Gilbert, James-C; Emsley, Jonas; Jilma, Bernd; O'Donnell, James-S (ELSEVIER, 2024-09)
    Rondaptivon pegol (previously BT200) is a pegylated RNA aptamer that binds to the A1 domain of von Willebrand factor (VWF). Recent clinical trials demonstrated that BT200 significantly increased plasma VWF-factor VIII ...
  • The Association of HIV-1 Neutralization in Aviremic Children and Adults with Time to ART Initiation and CD4+/CD8+ Ratios 
    Sánchez-Merino, Víctor; Martín-Serrano, Miguel; Beltran, Manuela; Lazaro-Martin, Beatriz; Cervantes, Eloisa; Oltra, Manuel; Sainz, Talia; García, Felipe; Navarro, María-Luisa; Yuste, Eloisa (MDPI, 2024-01)
    Broadly neutralizing antibodies (bnAbs) bind and neutralize diverse HIV isolates and demonstrate protective effects in primate models and humans against specific isolates. To develop an effective HIV vaccine, it is widely ...
  • The association of living donor source with patient and graft survival among kidney transplant recipients in the ERA-EDTA Registry - a retrospective study 
    Abd-ElHafeez, Samar; Noordzij, Marlies; Kramer, Anneke; Bell, Samira; Savoye, Emilie; Abad-Diez, José-María; Lundgren, Torbjorn; Reisater, Anna-Varberg; Kerschbaum, Julia; Santiuste-de-Pablos, Carmen; Ortiz, Fernanda; Collart, Frederic; Palsson, Runolfur; Arici, Mustafa; Heaf, James-G; Massy, Ziad-A; Jager, Kitty-J (WILEY, 2021-01)
    In this study we aimed to compare patient and graft survival of kidney transplant recipients who received a kidney from a living-related donor (LRD) or living-unrelated donor (LUD). Adult patients in the ERA-EDTA Registry ...
  • The Atrial Fibrillation Better Care (ABC) Pathway and Clinical Outcomes in Patients with Atrial Fibrillation: the Prospective Murcia AF Project Phase II Cohort 
    Rivera-Caravaca, José-Miguel; Roldán-Schilling, Vanesa; Martínez-Montesinos, Lorena; Vicente, Vicente; Lip, Gregory-YH; Marín, Francisco (Springer, 2023-02)
    BACKGROUND: The Atrial fibrillation Better Care (ABC) pathway was proposed for a more holistic or integrated care approach to atrial fibrillation (AF) management. We investigated whether adherence with the ABC pathway ...
  • The CARBA-MAP study: national mapping of carbapenemases in Spain (2014-2018) 
    Gracia-Ahufinger, Irene; López-González, Laura; Vasallo, Francisco-José; Galar, Alicia; Siller, María; Pitart, Cristina; Bloise, Ivan; Torrecillas, Miriam; Gijon-Cordero, Desiree; Vinado, Belén; Castillo-García, Javier; Campo, Rainer; Mulet, Xavier; Madueno-Alonso, Ana; Chamizo-López, Francisco-Javier; Arrastia-Erviti, Maitane; Galan-Sánchez, Fatima; Fernández-Quejo, Melisa; Rodríguez-Diaz, Juan-Carlos; Gutiérrez-Zufiaurre, María-Nieves; Rodríguez-Maresca, Manuel-Ángel; Ortega-Lafont, María-del-Pilar; Yague-Guirao, Genoveva; Chaves-Blanco, Lucía; Colomina-Rodríguez, Javier; Vidal-Acuna, María-Reyes; Portillo, María-Eugenia; de-Luna, Francisco-Franco-Álvarez; Centelles-Serrano, María-José; Azcona-Gutiérrez, José-Manuel; Campero, Alberto-Delgado-Iribarren-García; Rey-Cao, Sonia; Muñoz, Patricia; Calvo-Montes, Jorge; Zboromyrska, Yuliya; Grandioso, David; Camara, Jordi; Canton, Rafael; Larrosa-Escartin, Nieves; Diaz-Reganon, Jazmin; Martínez-Martínez, Luis (FRONTIERS MEDIA SA, 2023-09)
    INTRODUCTION: Infections caused by carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant Pseudomonas aeruginosa, including isolates producing acquired carbapenemases, constitute a prevalent health problem ...
  • The challenge of hepatic vein reconstruction in surgical oncology 
    López-López, Víctor; Ferreras, David; Eshmuminov, Dilmurodjon; Brusadin, Roberto; Robles-Campos, Ricardo (AME PUBLISHING COMPANY, 2022-06)
  • The community pharmacy as a strategic ally in the fight against Chagas disease 
    Simón, Marina; Ladrón-de-Guevara, Pilar; Polo, Sergio-Antonio; Sierra, Sandra; Segovia, Manuel (Elsevier Inc., 2023)
  • The COVID-19 Pandemic and Its Impact on Homebound Nursing Students 
    Gallego-Gómez, Juana-Inés; Campillo-Cano, María; Carrión-Martínez, Aurora; Balanza, Serafin; Rodríguez-González-Moro, María-Teresa; Simonelli-Muñoz, Agustín-Javier; Rivera-Caravaca, José-Miguel (MDPI, 2020-10)
    University students are predisposed to stress, which could be even higher in Nursing students since they are directly related to the COVID-19 pandemic given their health training and area of knowledge. Our purpose was to ...
  • The Early Appearance of Asthma and Its Relationship with Gut Microbiota: A Narrative Review 
    Suárez-Martínez, Clara; Santaella-Pascual, Marina; Yague-Guirao, Genoveva; García-Marcos, Luis; Ros, Gaspar; Martínez-Gracia, Carmen (MDPI, 2024-07)
    Asthma is, worldwide, the most frequent non-communicable disease affecting both children and adults, with high morbidity and relatively low mortality, compared to other chronic diseases. In recent decades, the prevalence ...
  • The effect of intravenous ferric carboxymaltose on heatlh-related quality of life in iron-deficient patients with acute heart failure: the results of the AFFIRM-AHF study 
    Jankowska, Ewa-A; Kirwan, Bridget-Anne; Kosiborod, Mikhail; Butler, Javed; Anker, Stefan-D; McDonagh, Theresa; Dorobantu, María; Drozdz, Jaroslaw; Filippatos, Gerasimos; Keren, Andre; Khintibidze, Irakli; Kragten, Hans; Martínez, Felipe-A; Metra, Marco; Milicic, Davor; Nicolau, José-C; Ohlsson, Marcus; Parkhomenko, Alexander; Pascual-Figal, Domingo-Andrés; Ruschitzka, Frank; Sim, David; Skouri, Hadi; van-der-Meer, Peter; Lewis, Basil-S; Comin-Colet, Josep; von-Haehling, Stephan; Cohen-Solal, Alain; Danchin, Nicolas; Doehner, Wolfram; Dargie, Henry-J; Motro, Michael; Friede, Tim; Fabien, Vincent; Dorigotti, Fabio; Pocock, Stuart; Ponikowski, Piotr (OXFORD UNIV PRESS, 2021-08-14)
    AIMS: Patients with heart failure (HF) and iron deficiency experience poor health-related quality of life (HRQoL). We evaluated the impact of intravenous (IV) ferric carboxymaltose (FCM) vs. placebo on HRQoL for the ...
  • The Effect of Sterilization on the Characteristics of Silk Fibroin Nanoparticles 
    Ruiz, María-Alejandra-Asensio; Fuster, Marta-G; Martínez, Teresa-Martínez; Montalban, Mercedes-G; Cenis, José-Luis; Villora, Gloria; Lozano-Pérez, Antonio-Abel (MDPI, 2022-02)
    In recent years, silk fibroin nanoparticles (SFNs) have been consolidated as drug delivery systems (DDSs) with multiple applications in personalized medicine. The design of a simple, inexpensive, and scalable preparation ...
  • The Expanding Phenotypical Spectrum of WARS2-Related Disorder: Four Novel Cases with a Common Recurrent Variant 
    Pauly, Martje-G; Korenke, GChristoph; Diaw, Sokhna-Haissatou; Groezinger, Anne; Cazurro-Gutiérrez, Ana; Pérez-Duenas, Belén; González, Victoria; Macaya, Alfons; Anton, Ana-Teresa-Serrano; Peterlin, Borut; Bozovic, Ivana-Babic; Maver, Ales; Muenchau, Alexander; Lohmann, Katja (MDPI, 2023-04)
    Biallelic variants in the mitochondrial form of the tryptophanyl-tRNA synthetases (WARS2) can cause a neurodevelopmental disorder with movement disorders including early-onset tremor-parkinsonism syndrome. Here, we describe ...
  • The expression of immune response genes in patients with chronic Chagas disease is shifted toward the levels observed in healthy subjects as a result of treatment with Benznidazole 
    Gómez, Inmaculada; Egui, Adriana; Palacios, Genesis; Carrilero, Bartolome; Benitez, Celia; Simon, Marina; Segovia, Manuel; Carmelo, Emma; López, Manuel-Carlos; Thomas, MCarmen (FRONTIERS MEDIA SA, 2024-07)
    INTRODUCTION: Chagas disease, caused by the Trypanosoma cruzi parasite infection, is a potentially life-threatening neglected tropical disease with a worldwide distribution. During the chronic phase of the disease, there ...

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