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Listar 02.01.01. Investigación y comunicación científica por título

Listar 02.01.01. Investigación y comunicación científica por título

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  • P2X7 receptor activation impairs antitumour activity of natural killer cells 
    Baroja-Mazo, Alberto; Penin-Franch, Alejandro; Lucas-Ruiz, Fernando; De-Torre-Minguela, Carlos; Alarcón-Vila, Cristina; Hernández-Caselles, Trinidad; Pelegrín, Pablo (WILEY, 2023-01)
    BACKGROUND AND PURPOSE: A high number of intratumoural infiltrating natural killer (NK) cells is associated with better survival in several types of cancer, constituting an important first line of defence against tumours. ...
  • P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis 
    Martínez-García, Juan-José; Martínez-Banaclocha, Helios; Angosto-Bazarra, Diego; de-Torre-Minguela, Carlos; Baroja-Mazo, Alberto; Alarcón-Vila, Cristina; Martínez-Alarcón, Laura; Amores-Iniesta, Joaquín; Martín-Sánchez, Fatima; Ercole, Giovanni-A; Martínez, Carlos-M; González-Lisorge, Ada; Fernández-Pacheco, José; Martínez-Gil, Piedad; Adriouch, Sahil; Koch-Nolte, Friedrich; Lujan, Juan; Acosta-Villegas, Francisco; Parrilla-Paricio, Pascual; García-Palenciano, Carlos; Pelegrín, Pablo (NATURE PORTFOLIO, 2019-06-20)
    Sepsis is characterized by a systemic inflammatory response followed by immunosuppression of the host. Metabolic defects and mitochondrial failure are common in immunocompromised patients with sepsis. The NLRP3 inflammasome ...
  • P2X7 receptor induces Tumor necrosis Factor-a converting enzyme activation and release to Boost TnF-ae Production 
    Barberá-Cremades, María; Gómez, Ana-I; Baroja-Mazo, Alberto; Martínez-Alarcón, Laura; Martínez, Carlos-M; de-Torre-Minguela, Carlos; Pelegrín, Pablo (FRONTIERS MEDIA SA, 2017-07-24)
    Tumor necrosis factor (TNF)-? is a major pro-inflammatory cytokine produced in response to toll-like receptor stimulation. TNF-? release is controlled by the activity of TNF-? converting enzyme (TACE) that cut membrane-bound ...
  • Paediatric endoscopy in Spain: Current situation and recent developments 
    Rubio, María-Navalon; Casano, Carmen-Jovani; Soria-López, Marta; Rodríguez-Herrera, Alfonso; López-Casado, Miguel-Ángel; Navas-López, Víctor-Manuel; Miravet, Víctor-Vila (EDICIONES DOYMA S A, 2024-12)
    INTRODUCTION: Paediatric gastrointestinal endoscopy (pGIE) has advanced significantly over the last decade, with increased diagnostic and therapeutic applications. OBJECTIVES: This study examines the current state of pGIE ...
  • Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition 
    Breeur, Marie; Ferrari, Pietro; Dossus, Laure; Jenab, Mazda; Johansson, Mattias; Rinaldi, Sabina; Travis, Ruth-C; His, Mathilde; Key, Timothy-J; Schmidt, Julie-A; Overvad, Kim; Tjonneland, Anne; Kyro, Cecilie; Rothwell, Joseph-A; Laouali, Nasser; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena-A; Schulze, Matthias-B; Eichelmann, Fabian; Palli, Domenico; Grioni, Sara; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Bas; Olsen, Karina-Standahl; Sandanger, Torkjel-Manning; Nost, Therese-Haugdahl; Quirós, José-Ramón; Bonet, Catalina; Rodríguez-Barranco, Miguel; Chirlaque-López, María-Dolores; Ardanaz, Eva; Sandsveden, Malte; Manjer, Jonas; Vidman, Linda; Rentoft, Matilda; Muller, David; Tsilidis, Kostas; Heath, Alicia-K; Keun, Héctor; Adamski, Jerzy; Keski-Rahkonen, Pekka; Scalbert, Augustin; Gunter, Marc-J; Viallon, Vivian (BMC, 2022-10)
    BACKGROUND: Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately. Here, we designed a multivariate pan-cancer analysis to identify metabolites ...
  • Pancreas units within gastroenterology departments. Organizational and operational standards for a patient-centered service 
    Domínguez-Muñoz, JEnrique; Martínez-Moneo, Emma; Bolado-Concejo, Federico; Alberca-de-las-Parras, Fernando; Carballo-Álvarez, Fernando; Elola-Somoza, F-Javier (Arán Ediciones, 2024)
    The Asociación Española de Pancreatología (AESPANC), Asociación Española de Gastroenterología (AEG), and Sociedad Española de Patología Digestiva (SEPD) have developed a consensus document on the standards and recommendations ...
  • Pancreatic encephalopathy, a little known complication of acute pancreatitis 
    Albacete-Ródenas, Paloma; Ortiz-Sánchez, María-Luisa; Gajownik, Urszula; Alberca-de-las-Parras, Fernando; Pons-Miñano, José-Antonio (Arán Ediciones, 2022)
    A 62-year-old male presented with severe post-endoscopic retrograde cholangiopancreatography (post-ERCP) acute pancreatitis. He required admission to the Intensive Care Unit (ICU) twice due to respiratory and renal failure ...
  • Parachute mitral valve repair in adult patient with transitional atrioventricular septal defect 
    Aguilar, Juan-M; Jiménez, Antonio; Pérez-Andreu, Joaquín; Fernández, Manuel; Lorenzo, Maydelin; Cánovas-López, Sergio-J (ELSEVIER, 2022-05)
  • Paradigmatic De Novo GRIN1 Variants Recapitulate Pathophysiological Mechanisms Underlying GRIN1-Related Disorder Clinical Spectrum 
    Santos-Gómez, Ana; Miguez-Cabello, Federico; Julia-Palacios, Natalia; García-Navas, Deyanira; Soto-Insuga, Víctor; García-Penas, Juan-J; Fuentes, Patricia; Ibañez-Mico, Salvador; Cuesta, Laura; Cancho, Ramón; Andreo-Lillo, Patricia; Gutiérrez-Aguilar, Gema; Alonso-Luengo, Olga; Malaga, Ignacio; Hedrera-Fernández, Antonio; García-Cazorla, Ángels; Soto, David; Olivella, Mireia; Altafaj, Xavier (MDPI, 2021-12)
    BACKGROUND: GRIN-related disorders (GRD), the so-called grinpathies, is a group of rare encephalopathies caused by mutations affecting GRIN genes (mostly GRIN1, GRIN2A and GRIN2B genes), which encode for the GluN subunit ...
  • Parental Education and the Association between Fruit and Vegetable Consumption and Asthma in Adolescents: The Greek Global Asthma Network (GAN) Study 
    Antonogeorgos, George; Priftis, Kostas-N; Panagiotakos, Demosthenes-B; Ellwood, Philippa; García-Marcos, Luis; Liakou, Evangelia; Koutsokera, Alexandra; Drakontaeidis, Pavlos; Thanasia, Marina; Mandrapylia, María; Douros, Konstantinos (MDPI, 2021-04)
    BACKGROUND: Evidence suggests that nutritional factors, such as consumption of fruits and vegetables, along with socioeconomic factors such as parental education level, are associated with asthma prevalence. Our study ...
  • Parental Education Moderates the Relation between Physical Activity, Dietary Patterns and Atopic Diseases in Adolescents 
    Antonogeorgos, George; Panagiotakos, Demosthenes-B; Priftis, Kostas-N; Liakou, Evangelia; Koutsokera, Alexandra; Drakontaeidis, Pavlos; Thanasia, Marina; Mandrapylia, María; Moriki, Dafni; Ellwood, Philippa; García-Marcos, Luis; Douros, Konstantinos (MDPI, 2022-05)
    Background: Atopic diseases, particularly asthma, eczema, and rhinitis, are among the most common chronic diseases in childhood, with several factors implicated in their pathogenesis. Our study examined the role of parental ...
  • Parental presence during invasive pediatric procedures: what does it depend on? 
    Palomares-González, Laura; Hernández-Caravaca, Iván; Gómez-García, Carmen-Isabel; Sánchez-Solís-de-Querol, Manuel (UNIV SAO PAULO, ESCOLA DE ENFERMAGEM DE RIBEIRAO PRETO, 2023)
    OBJECTIVE: family-centered care during invasive procedures has been endorsed by many professional health care organizations. The aim of this study was to evaluate the health professionals' attitudes towards parental presence ...
  • Paroxysmal nocturnal hemoglobinuria and liver transplantation, a new paradigm 
    Morilla-Fernández, José-Antonio; Sánchez-Martínez, Ana; Pons-Miñano, José-Antonio (Arán Ediciones, 2021)
    Paroxysmal nocturnal hemoglobinuria (PNH) is a type of hemolytic anemia acquired by the PIG-A gene mutation. This causes a deficiency of a complement regulatory protein, CD59, which results in hemolysis, hemoglobinuria and ...
  • Participant-funded clinical trials on rare diseases 
    Dal-Re, Rafael; Palau, Francesc; Guillén-Navarro, Encarna; Ayuso, Carmen (EDICIONES DOYMA S A, 2020-10)
    The development of medicines for certain rare diseases can be frustrated by lack of funding. In certain cases the patients themselves, or their relatives, occasionally fund the clinical trial in which they will be treated ...
  • Particulate Matter Exposure during Pregnancy and Childhood Leukemia Incidence 
    sanz-Olea, Enrique; Ojeda-Sánchez, Carlos; Guxens, Mónica; Canete, Adela; Pardo-Romaguera, Elena; Gómez-Barroso, Diana; García-Pérez, Javier; Núñez-Corcuera, Beatriz; Ortega-García, Juan-Antonio; Ramis, Rebeca (MDPI, 2024-07)
  • Patch test results to the Spanish baseline patch test series according to age groups: A multicentric prospective study from 2019 to 2023 
    Pesque, David; Planella-Fontanillas, Nidia; Borrego, Leopoldo; Sanz-Sánchez, Tatiana; Zaragoza-Ninet, Violeta; Serra-Baldrich, Esther; Miquel-Miquel, Francisco-Javier; Silvestre-Salvador, Juan-Francisco; Córdoba-Guijarro, Susana; Sánchez-Gilo, Araceli; Mercader-García, Pedro; Navarro-Triviño, Francisco-José; Ortiz-de-Frutos, Francisco-Javier; Tous-Romero, Fátima; Rodríguez-Serna, Mercedes; Mele-Ninot, Gemma; Barrabes-Torrella, Cristina; Ruiz-González, Inmaculada; Pastor-Nieto, María-Antonia; Carrascosa-Carrillo, José-Manuel; Gómez-de-la-Fuente, Enrique; Sánchez-Pedreño-Guillén, Paloma; Sánchez-Pérez, Javier; Pereyra-Rodríguez, José-Juan; Gatica-Ortega, María-Elena; González-Pérez, Ricardo; Pujol, Ramon-María; Gallego-Descalzo, Miguel-Ángel; García-Doval, Ignacio; Giménez-Arnau, Ana-María (WILEY, 2025-02)
    INTRODUCTION: Patch test results may be influenced by age-related factors. However, there is still discordant evidence between age and patch test results. OBJECTIVES: We aim to evaluate the patch test results reflecting ...
  • Pathway to effective treatment for common mental and substance use disorders in the World Mental Health Surveys: Perceived need for treatment 
    Harris, Meredith-G; Kazdin, Alan-E; Hwang, Irving; Manoukian, Sophie-M; Sampson, Nancy-A; Stein, Dan-J; Viana-Llamas, María-Carmen; Vigo, Daniel-V; Alonso, Jordi; Andrade, Laura-Helena; Bruffaerts, Ronny; Bunting, Brendan; Caldas-de-Almeida, José-Miguel; Chardoul, Stephanie; de-Girolamo, Giovanni; Gureje, Oye; Haro, Josep-María; Karam, Elie-G; Kovess-Masfety, Viviane; Medina-Mora, María-Elena; Navarro-Mateu, Fernando; Nishi, Daisuke; Posada-Villa, José; Rapsey, Charlene; Stagnaro, Juan-Carlos; ten-Have, Margreet; Wciorka, Jacek; Zarkov, Zahari; Kessler, Ronald-C (BMC, 2025-05-23)
    BACKGROUND: Perceived need for treatment is a first step along the pathway to effective mental health treatment. Perceived need encompasses a person's recognition that they have a problem and their belief that professional ...
  • Patient and graft survival in pancreas transplant recipients: The EFISPAN study 
    Ventura-Aguiar, Pedro; Cabello, Mercedes; Beneyto, Isabel; Navarro-Cabello, Dolores; Tabernero, Guadalupe; Alonso, Ángel; Ruiz, Juan-Carlos; Llorente-Viñas, Santiago (SOC ESPANOLA NEFROLOGIA DR RAFAEL MATESANZ, 2023-01)
  • Patient selection, peri-procedural management, and ablation techniques for catheter ablation of atrial fibrillation: an EHRA survey 
    Iliodromitis, Konstantinos; Lenarczyk, Radoslaw; Scherr, Daniel; Conte, Giulio; Farkowski, Michal-M; Marín, Francisco; García-Seara, Javier; Simovic, Stefan; Potpara, Tatjana (OXFORD UNIV PRESS, 2023-02)
    Catheter ablation (CA) of atrial fibrillation (AF) is the therapy of choice for the maintenance of sinus rhythm in patients with symptomatic AF. Time towards interventional treatment and peri-procedural management of ...
  • Patient With Prolidase Deficiency due to an Homozygous PEPD Variant, Induced by Paternal Uniparental Isodisomy of Chromosome 19 
    Carreno-Hidalgo, Marta; Muñoz-Siles, Raquel; López-González, Vanesa; Carreno-Gago, Lidia; Armengol-Dulcet, Lluis (WILEY, 2025-10)
    Uniparental disomy (UPD) is a rare phenomenon in which both copies of a chromosome are inherited from a single parent. This can lead to genomic imprinting disorders and recessive disorders due to the presence of recessive ...

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