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Listar 02.01. Área de Salud I Murcia Oeste por título

Listar 02.01. Área de Salud I Murcia Oeste por título

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  • A Multi-Target Pharmacological Correction of a Lipoyltransferase LIPT1 Gene Mutation in Patient-Derived Cellular Models 
    Gomez-Fernández, David; Romero-González, Ana; Suárez-Rivero, Juan-M; Cilleros-Holgado, Paula; Álvarez-Cordoba, Mónica; Piñero-Perez, Rocío; Romero-Dominguez, José-Manuel; Reche-López, Diana; López-Cabrera, Alejandra; Ibáñez-Micó, Salvador; Castro-de-Oliveira, Marta (MDPI, 2024-08)
    Simple Summary Cardiovascular diseases represent the leading cause of mortality and morbidity worldwide, and age is an important contributing factor. Preclinical models are crucial for exploring and understanding the ...
  • A Multicenter Study by the DENO Research Group on the Use of Denosumab in Giant-Cell Tumors of the Bone 
    de-la-Calva-Ceinos, Carolina; Angulo, Manuel; González-Rojo, Paula; Peiró, Ana; Machado, Pau; Cebrian, Juan-Luis; García-Maroto, Roberto; Valcárcel, Antonio; Puertas, Pablo; Valero-Cifuentes, Gregorio; Pablos, Oscar; Maireles, Miriam; Fontalva, María-Luisa; Chaves, Iván; Orce, Aida; Coll-Mesa, Luis; Pérez, Israel; González, Fausto; Sanz, María-del-Carmen; Gracia, Isidro (MDPI, 2025-05-07)
    Background/Objectives: Despite the therapeutic potential of denosumab for the treatment of giant-cell tumors of the bone (GCTBs), there is a lack of standardization in treatment protocols. Methods: We present a multicenter, ...
  • A Multicentre Study of the Attitude of Medical Students towards Organ Donation and Transplantation in Poland 
    Mikla, Marzena; Cybulska, Anna-María; Schneider-Matyka, Daria; Ríos, Antonio; Panczyk, Mariusz; Kotwas, Artur; Karakiewicz, Beata; Grochans, Elzbieta (MDPI, 2023)
    To analyze the neuroprotective effects of 7,8-Dihydroxyflavone (DHF) in vivo and ex vivo, adult albino Sprague-Dawley rats were given a left intraorbital optic nerve transection (IONT) and were divided in two groups: One ...
  • A multicriteria decision analysis (MCDA) applied to three long-term prophylactic treatments for hereditary angioedema in Spain 
    Zozaya, Neboa; Caballero, Teresa; González-Quevedo, Teresa; Gamboa-Setien, Pedro; Ángeles-González, Ma; Jodar, Ramón; Luis-Poveda-Andres, José; Guillén-Navarro, Encarna; Cuadrado, Agustín-Rivero; Hidalgo-Vega, Álvaro (ABOUTSCIENCE SRL, 2022-01-25)
    Introduction: Hereditary angioedema (HAE) is a rare genetic disease that impairs quality of life and could be life-threatening. The aim of this study was to apply a multicriteria decision analysis to assess the value of ...
  • A multimodal approach to detect and monitor early lung disease in cystic fibrosis 
    Mondéjar-López, Pedro; Horsley, Alexander; Ratjen, Felix; Bertolo, Silvia; de-Vicente, Helene; Asensio-de-la-Cruz, Oscar (TAYLOR & FRANCIS LTD, 03/06/2021)
    Introduction: In the early stages, lung involvement in cystic fibrosis (CF) can be silent, with disease progression occurring in the absence of clinical symptoms. Irreversible airway damage is present in the early stages ...
  • A new approach to the intracardiac inverse problem using Laplacian distance kernel 
    Caulier-Cisterna, Raúl; Muñoz-Romero, Sergio; Sanroman-Junquera, Margarita; García-Alberola, Arcadio; Rojo-Álvarez, José-Luis (BMC, 2018-06-20)
    BACKGROUND: The inverse problem in electrophysiology consists of the accurate estimation of the intracardiac electrical sources from a reduced set of electrodes at short distances and from outside the heart. This estimation ...
  • A new blood DNA methylation signature for Koolen-de Vries syndrome: Classification of missense KANSL1 variants and comparison to fibroblast cells 
    Awamleh, Zain; Choufani, Sanaa; Wu, Wendy; Rots, Dmitrijs; Dingemans, Alexander-J-M; Khadri, Nael-Nadif; Boronat, Susana; Ibáñez-Micó, Salvador; Cuesta-Herraiz, Laura; Ferrer, Irene; Martínez-Carrascal, Antonio; Pérez-Jurado, Luis-A; Aznar-Laín, Gemma; Ortigoza-Escoba, (SPRINGERNATURE, 2024-03)
    Pathogenic variants in KANSL1 and 17q21.31 microdeletions are causative of Koolen-de Vries syndrome (KdVS), a neurodevelopmental syndrome with characteristic facial dysmorphia. Our previous work has shown that syndromic ...
  • A New Comorbidity in Periodontitis: Fusobacterium nucleatum and Colorectal Cancer 
    Mesa, Francisco; Mesa-López, María-José; Egea-Valenzuela, Juan; Benavides-Reyes, Cristina; Nibali, Luigi; Ide, Mark; Mainas, Giuseppe; Rizzo, Manfredi; Magan-Fernández, Antonio (MDPI, 2022-04)
    3,4,5-Trimethoxybenzoate of catechin (TMBC) is a semisynthetic catechin which shows strong antiproliferative activity against malignant melanoma cells. The amphiphilic nature of the molecule suggests that the membrane could ...
  • A New Management Technique for Symptomatic Haematomas Following Therapeutic Vacuum-Assisted Biopsy 
    Guzmán-Aroca, Florentina; Berna-Serna, Juan-de-Dios; Azahara-García-Ortega, Ana; Hernández-Gómez, Dolores; Berna-Mestre, Juan-de-Dios (MDPI, 2019-09)
    The aim of this study was to investigate the efficacy of the vacuum-assisted biopsy (VAB) system in evacuating symptomatic haematomas after VAB excision of benign breast lesions. We retrospectively analysed the data of ...
  • A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia 
    Arriazu, Elena; Vicente, Carmen; Pippa, Raffaella; Peris, Irene; Martínez-Balsalobre, Elena; García-Ramírez, Patricia; Marcotegui, Nerea; Igea, Ana; Alignani, Diego; Rifon, José; Mateos, María-C; Cayuela-Fuentes, María-Luisa; Nebreda, Ángel-R; Odero, María-D (NATURE PUBLISHING GROUP, 2020-01-08)
    Acute myeloid leukemia (AML) is an aggressive hematologic malignancy. Although novel emerging drugs are available, the overall prognosis remains poor and new therapeutic approaches are required. PP2A phosphatase is a key ...
  • A New Technique for Computed-Tomography Urethrography in Males: The Clamp Method 
    Berna-Mestre, Juan-de-Dios; Guzmán-Aroca, Florentina; Puerta-Sales, Alejandro; Navarro-Bano, Antonio; Carbonell-López-del-Castillo, Guillermo; Berna-Serna, Juan-de-Dios; Alcaraz, Miguel (MDPI, 2021-02)
    The oviduct plays important roles in reproductive events: sperm reservoir formation, final gamete maturation, fertilization and early embryo development. It is well known that the oviductal environment affects gametes and ...
  • A New Therapeutic Application of Platelet-Rich Plasma to Chronic Breast Wounds: A Prospective Observational Study 
    Berna-Serna, Juan-de-Dios; Guzmán-Aroca, Florentina; García-Vidal, José-Antonio; Hernández-Gómez, Dolores; Azahara-García-Ortega, Ana; Chivato-Martín-Falquina, Tomás; Piñero-Madrona, Antonio; Berna-Mestre, Juan-de-Dios (MDPI, 2020-10)
    Pooling metabolomics data across studies is often desirable to increase the statistical power of the analysis. However, this can raise methodological challenges as several preanalytical and analytical factors could introduce ...
  • A New Treatment for Mammillary Fistulas Using Ultrasound-Guided Percutaneous Needle Electrolysis 
    Berna-Serna, Juan-de-Dios; García-Vidal, José-Antonio; Escolar-Reina, Pilar; Medina-Mirapeix, Francesc; Guzmán-Aroca, Florentina; Piñero-Madrona, Antonio; Berna-Mestre, Juan-de-Dios (MDPI, 2020-03)
    The aim of this study was to investigate the efficacy of ultrasound-guided percutaneous needle electrolysis (PNE) in mammillary fistulas (MFs). A prospective study was performed in 18 patients with MF who were treated with ...
  • A Newborn Screening Program for Sickle Cell Disease in Murcia (Spain) 
    Sánchez-Villalobos, María; Campos-Baños, Eulalia; Juan-Fita, María-Jesús; Egea-Mellado, José-María; González-Gallego, Inmaculada; Beltrán-Videla, Asunción; Berenguer-Piqueras, Mercedes; Bermúdez-Cortes, Mar; Moraleda-Jiménez, José-María; Guillén-Navarro, Encarna; F, (MDPI, 2023-12)
    Several studies have reported that viral infection is closely associated with the onset, progression, and exacerbation of asthma. The purpose of this review is to summarize the role that viral infections have in the ...
  • A novel and efficient tandem CD19-and CD22-directed CAR for B cell ALL 
    Zanetti, Samanta-Romina; Velasco-Hernández, Talia; Gutiérrez-Agüera, Francisco; Díaz, Victor-M; Romecin, Paola-Alejandra; Roca-Ho, Heleia; Sánchez-Martínez, Diego; Tirado, Néstor; Baroni, Matteo-Libero; Petazzi, Paolo; Torres-Ruiz, Raúl; Molina, Óscar; Bataller, Alex (CELL PRESS, 02/02/2022)
    CD19-directed chimeric antigen receptor (CAR) T cells have yielded impressive response rates in refractory/relapse B cell acute lymphoblastic leukemia (B-ALL); however, most patients ultimately relapse due to poor CAR T ...
  • A novel chimeric antigen receptor T-cell therapy targeting CD84 for the treatment of acute myeloid and T-cell lymphoblastic leukemias 
    Pérez-Amill, Lorena; Armand-Ugon, Mercedes; Val-Casals, María; Martín-Herreros, Beatriz; Álamo, José-R; Peña, Sergio; Frigola, Gerard; Altuna, Ane; Santos, Claudio; Guijarro, Francesca; Minguela-Puras, Alfredo; Bataller, Alex; Casanovas-Alberti, Berta; Uribe-Herranz, Mireia; Navarro, Irene; Guerreiro, Manuel; Sánchez-Martínez, Diego; Tirado, Nestor; Velasco-Hernández, Talia; Menéndez, Pablo; Martínez, Antonio; Rovira, Montse; Colomer, Dolors; González-Navarro, Europa-Azucena; Esteve, Jordi; Urbano-Ispizua, Álvaro; Montesinos, Pau; Delgado, Julio; Juan, Manel; Klein-González, Nela (SPRINGERNATURE, 2025-10)
    Despite the remarkable clinical successes of chimeric antigen receptor (CAR) T-cell therapies in treating B-cell malignancies and multiple myeloma, similar outcomes have not been achieved in other indications. For patients ...
  • A novel explainable AI framework for medical image classification integrating statistical, visual, and rule-based methods 
    Ullah, Naeem; Guzmán-Aroca, Florentina; Martínez-Álvarez, Francisco; De-Falco, Ivanoe; Sannino, Giovanna (ELSEVIER, 2025-10)
    Artificial intelligence and deep learning are powerful tools for extracting knowledge from large datasets, particularly in healthcare. However, their black-box nature raises interpretability concerns, especially in high-stakes ...
  • A Novel Mutation Associated with Neonatal Lethal Cardiomyopathy Leads to an Alternative Transcript Expression in the X-Linked Complex I NDUFB11 Gene 
    Amate-García, Guillermo; Ballesta-Martínez, María-Juliana; Serrano-Lorenzo, Pablo; Garrido-Moraga, Rocío; González-Quintana, Adrián; Blázquez, Alberto; Rubio, Juan-C; García-Consuegra, Inés; Arenas, Joaquín; Ugalde, Cristina; Morán, María; Guillén-Navarro, Encarna (MDPI, 2023-01)
    Sickle cell disease (SCD) is an inherited autosomal recessive hemoglobin disorder caused by the presence of hemoglobin S, a mutant abnormal hemoglobin caused by a nucleotide change in codon 6 of the beta-globin chain gene. ...
  • A Practical Method for Monitoring Patient Safety Culture: Applying Net Promoter Score and Lot Quality Assurance Sampling 
    López-Picazo-Ferrer, Julio-J; Vidal-Abarca, Inmaculada; Marín-Martínez, Juana-María (WILEY, 2026-04)
    RATIONALE: Patient safety culture is a key component of health care quality, yet its integration into routine monitoring systems is often limited. Existing assessments tend to focus on cross-sectional snapshots rather than ...
  • A prediction tool for malnutrition and sarcopenia in patients with gastroenteropancreatic neuroendocrine neoplasms: results from NUTRIGETNE (GETNE-S2109) study 
    Argente-Pla, María; Sampedro-Núñez, Miguel-Antonio; García-Carbonero, Rocío; Custodio, Ana; Hernando, Jorge; Suárez, Lorena; Hernández-Rienda, Lorena; Peiro, Inmaculada; Alonso, Vicente; Serrano, Raquel; Valdes, Nuria; Melian, Marcos; Febrero, Beatriz; Biarnes, Josefina; Díaz-Pérez, José-Angel; Molina-Cerrillo, Javier; López, Carlos; Martínez-Olmos, Miguel-Ángel; Merino-Torres, Juan-Francisco; Capdevila, Jaume; del-Olmo-García, Maribel (FRONTIERS MEDIA SA, 2026-05-26)
    INTRODUCTION: Malnutrition and sarcopenia are prevalent among patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs), necessitating simple assessment tools to identify potentially malnourished patients. ...

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