Repositorio Dspace

Listar01.01. Investigación y comunicación científica por tema "Genetic Predisposition to Disease"

Listar01.01. Investigación y comunicación científica por tema "Genetic Predisposition to Disease"

Ordenar por:Orden:Resultados:

  • Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status 
    Fedirko, Veronika; Jenab, Mazda; Meplan, Catherine; Jones, Jeb-S; Zhu, Wanzhe; Schomburg, Lutz; Siddiq, Afshan; Hybsier, Sandra; Overvad, Kim; Tjonneland, Anne; Omichessan, Hanane; Perduca, Vittorio; Boutron-Ruault, Marie-Christine; Kuehn, Tilman; Katzke, Verena; Aleksandrova, Krasimira; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Agnoli, Claudia; Naccarati, Alessio; Bueno-de-Mesquita, Bas; Vermeulen, Roel-C-H; Weiderpass, Elisabete; Skeie, Guri; Nost, Therese-Haugdahl; Lujan-Barroso, Leila; Quirós, José-Ramón; Huerta-Castaño, José-María; Rodríguez-Barranco, Miguel; Barricarte-Gurrea, Aurelio; Gylling, Bjoern; Harlid, Sophia; Bradbury, Kathryn-E; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc; Murphy, Neil; Freisling, Heinz; Tsilidis, Kostas; Aune, Dagfinn; Riboli, Elio; Hesketh, John-E; Hughes, David-J (MDPI, 2019-04)
    Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the risk of colorectal cancer (CRC) development. We examined the association between CRC risk and genotype for single nucleotide ...
  • Examining causal relationships between educational attainment and type 2 diabetes using genetic analysis: findings from the EPIC-InterAct study through Mendelian randomisation 
    Macciotta, Alessandra; Sacerdote, Carlotta; Giachino, Claudia; Di-Girolamo, Chiara; Franco, Matteo; van-der-Schouw, Yvonne-T; Zamora-Ros, Raúl; Weiderpass, Elisabete; Domenighetti, Cloe; Elbaz, Alexis; Truong, Therese; Agnoli, Claudia; Bendinelli, Benedetta; Panico, Salvatore; Vineis, Paolo; Christakoudi, Sofia; Schulze, Matthias-B; Katzke, Verena; Bajracharya, Rashmita; Dahm, Christina-C; Dalton, Susanne-Oksbjerg; Colorado-Yohar, Sandra; Moreno-Iribas, Conchi; Amiano-Etxezarreta, Pilar; Sánchez, María-José; Forouhi, Nita-G; Wareham, Nicholas; Ricceri, Fulvio (BMJ PUBLISHING GROUP, 2025-05)
    INTRODUCTION: Observational studies have shown that more educated people are at lower risk of developing type 2 diabetes (T2D). However, robust study designs are needed to investigate the likelihood that such a relationship ...
  • Inflammation and gut barrier function-related genes and colorectal cancer risk in western European populations 
    Mandle, Hannah-B; Jenab, Mazda; Gunter, Marc-J; Tjonneland, Anne; Olsen, Anja; Dahm, Christina-C; Zhang, Jie; Sugier, Pierre-Emmanuel; Rothwell, Joseph; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena-A; Schulze, Matthias-B; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Sacerdote, Carlotta; Bonet, Catalina; Sánchez, María-José; Amiano, Pilar; Huerta-Castaño, José-María; Guevara, Marcela; Palmqvist, Richard; Loewenmark, Thyra; Pérez-Cornago, Aurora; Weiderpass, Elisabete; Heath, Alicia-K; Cross, Amanda-J; Vineis, Paolo; Hughes, David-J; Fedirko, Veronika (OXFORD UNIV PRESS, 2025-03-15)
    Gut barrier dysfunction and related inflammation are known to be associated with the development and progression of colorectal cancer (CRC). We investigated associations of 292 single-nucleotide polymorphisms (SNPs) from ...
  • Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries 
    Li, Sherly-X; Imamura, Fumiaki; Schulze, Matthias-B; Zheng, Jusheng; Ye, Zheng; Agudo, Antonio; Ardanaz, Eva; Aune, Dagfinn; Boeing, Heiner; Dorronsoro, Miren; Dow, Courtney; Fagherazzi, Guy; Grioni, Sara; Gunter, Marc; Huerta-Castaño, José-María; Ibsen, Daniel-B; Jakobsen, Marianne-Uhre; Kaaks, Rudolf; Key, Timothy-J; Khaw, Kay-Tee; Kyro, Cecilie; Mancini, Francesca-Romana; Molina-Portillo, Elena; Murphy, Neil; Nilsson, Peter-M; Onland-Moret, N-Charlotte; Palli, Domenico; Panico, Salvatore; Poveda, Alaitz; Quirós, J-Ramón; Ricceri, Fulvio; Sluijs, Ivonne; Spijkerman, Annemieke-M-W; Tjonneland, Anne; Tumino, Rosario; Winkvist, Anna; Langenberg, Claudia; Sharp, Stephen-J; Riboli, Elio; Scott, Robert-A; Forouhi, Nita-G; Wareham, Nicholas-J (SPRINGER, 2018-06)
    AIMS/HYPOTHESIS: Gene-macronutrient interactions may contribute to the development of type 2 diabetes but research evidence to date is inconclusive. We aimed to increase our understanding of the aetiology of type 2 diabetes ...
  • Nature or nurture: genetic and environmental predictors of adiposity gain in adults 
    Peruchet-Noray, Laia; Dimou, Niki; Córdova, Reynalda; Fontvieille, Emma; Jansana, Anna; Gan, Quan; Breeur, Marie; Baurecht, Hansjoerg; Bohmann, Patricia; Konzok, Julián; Stein, Michael-J; Dahm, Christina-C; Zilhao, Nuno-R; Mellemkjaer, Lene; Tjonneland, Anne; Kaaks, Rudolf; Katzke, Verena; Inan-Eroglu, Elif; Schulze, Matthias-B; Masala, Giovanna; Sieri, Sabina; Simeon, Vittorio; Matullo, Giuseppe; Molina-Montes, Esther; Amiano, Pilar; Chirlaque-López, María-Dolores; Gasque, Alba; Atkins, Joshua; Smith-Byrne, Karl; Ferrari, Pietro; Viallon, Vivian; Agudo, Antonio; Gunter, Marc-J; Bonet, Catalina; Freisling, Heinz; Carreras-Torres, Robert (ELSEVIER, 2025-01)
    BACKGROUND: Previous prediction models for adiposity gain have not yet achieved sufficient predictive ability for clinical relevance. We investigated whether traditional and genetic factors accurately predict adiposity ...
  • The RS4939827 polymorphism in the SMAD7 GENE and its association with Mediterranean diet in colorectal carcinogenesis 
    Alonso-Molero, Jessica; González-Donquiles, Carmen; Palazuelos, Camilo; Fernández-Villa, Tania; Ramos, Elena; Pollan, Marina; Aragonés, Nuria; Llorca, Javier; Henar-Alonso, M; Tardon, Adonina; Amiano, Pilar; Jiménez-Moleon, José-Juan; Peiro-Pérez, Rosana; Capelo, Rocío; Molina, Antonio-J; Gómez-Acebo, Inés; Guevara, Marcela; Pérez-Gómez, Beatriz; Lope, Virginia; Huerta-Castaño, José-María; Castaño-Vinyals, Gemma; Kogevinas, Manolis; Moreno, Víctor; Martín, Vicente (BMC, 2017-10-30)
    BACKGROUND: The objective of our investigation is to study the relationship between the rs4939827 SNP in the SMAD7 gene, Mediterranean diet pattern and the risk of colorectal cancer. METHODS: We examined 1087 cases of ...
  • Vitamin D-Related Genes, Blood Vitamin D Levels and Colorectal Cancer Risk in Western European Populations 
    Fedirko, Veronika; Mandle, Hannah-B; Zhu, Wanzhe; Hughes, David-J; Siddiq, Afshan; Ferrari, Pietro; Romieu, Isabelle; Riboli, Elio; Bueno-de-Mesquita, Bas; van-Duijnhoven, Franzel-J-B; Siersema, Peter-D; Tjonneland, Anne; Olsen, Anja; Perduca, Vittorio; Carbonnel, Franck; Boutron-Ruault, Marie-Christine; Kuehn, Tilman; Johnson, Theron; Krasimira, Aleksandrova; Trichopoulou, Antonia; Makrythanasis, Periklis; Thanos, Dimitris; Panico, Salvatore; Krogh, Vittorio; Sacerdote, Carlotta; Skeie, Guri; Weiderpass, Elisabete; Colorado-Yohar, Sandra; Sala, Nuria; Barricarte-Gurrea, Aurelio; Sánchez, María-José; Quirós, José-Ramón; Amiano, Pilar; Gylling, Bjorn; Harlid, Sophia; Pérez-Cornago, Aurora; Heath, Alicia-K; Tsilidis, Konstantinos-K; Aune, Dagfinn; Freisling, Heinz; Murphy, Neil; Gunter, Marc-J; Jenab, Mazda (MDPI, 2019-08)
    Higher circulating 25-hydroxyvitamin D levels (25(OH)D) have been found to be associated with lower risk for colorectal cancer (CRC) in prospective studies. Whether this association is modified by genetic variation in genes ...

Buscar en DSpace


Búsqueda avanzada

Listar

Mi cuenta