02.06. Área de Salud VI Vega Media

The importance of the doctor-patient relationship in the adherence of chronic patients to treatment: a multicentre cross-sectional study

Thu, 01 Jan 2026 00:00:00 GMT

The importance of the doctor-patient relationship in the adherence of chronic patients to treatment: a multicentre cross-sectional study Zarza-Arribas, María; Menárguez-Puche, Juan-Francisco; Morales-López, Rosario; Barber-Valles, Josep-Xavier; Orozco-Beltrán, Domingo-Luis; Collaborative-group, OBJECTIVES: To assess the association of the doctor-patient relationship with adherence to treatment (AT) and lifestyle recommendations in patients with multimorbidity. DESIGN: Multicentre, descriptive, cross-sectional study. SETTING: Primary care. PARTICIPANTS: 202 patients diagnosed with two or more chronic pathologies, from 23 health centres. INTERVENTIONS: Self-administered questionnaires validated in our setting: Therapeutic Adherence Scale (EAT, for its acronym in Spanish) and perception of doctor-patient relationship (PREMEPA questionnaire). Descriptive, bivariate analysis, and multivariate modelling (log-linear analysis). MAIN OUTCOMES MEASURES: Categorical adherence score according to the Therapeutic Adherence Scale (EAT) and categorical doctor-patient relationship score according to the Physician-Patient Relationship Perception Questionnaire (PREMEPA questionnaire). RESULTS: 56.1% of the patients were women and 67% were over 60 years of age. Adherence was high in 52.2%, with very high adherence in 42.8%. Adequate doctor-patient relationship was reported by 86.6% of patients. There was a statistically significant but weak association (Cramer's V = 0.182) between doctor-patient relationship and adherence (p < 0.05), with a higher degree of relationship found in women and those over 60 years of age. Generalized linear statistical analysis showed a significant model with a positive association between AT and empathy, courtesy, patient participation in decision-making and return. CONCLUSIONS: Adequate doctor-patient relationship was associated with greater adherence to treatment. Empathy was the component of doctor-patient relationship that showed the strongest association with adherence. Courtesy and patient participation are favourable factors for adequate adherence.

Imaging-Guided Respiratory Care: The Role of Chest Radiography, Computed Tomography, and Lung Ultrasound in Respiratory Therapy Practice

Fri, 25 Sep 2026 00:00:00 GMT

Imaging-Guided Respiratory Care: The Role of Chest Radiography, Computed Tomography, and Lung Ultrasound in Respiratory Therapy Practice Eldhos-Jacob; P, Ajay-Chand; Esquinas-Rodríguez, Antonio Imaging is an integral component of contemporary respiratory and critical care, providing structural and increasingly functional information that complements clinical examination, respiratory physiology, and monitoring. Respiratory therapists (RTs) participate in the assessment and management of patients receiving oxygen therapy, noninvasive respiratory support, invasive mechanical ventilation, airway clearance, and weaning. Understanding clinically relevant thoracic imaging can therefore support timely recognition of respiratory deterioration and communication within multidisciplinary teams. This narrative review examines the roles of chest radiography, computed tomography (CT), and lung ultrasound (LUS) in respiratory therapy (RT) practice and considers how imaging can be integrated with bedside physiological assessment. Chest radiography remains important for evaluating pulmonary opacities, atelectasis, pulmonary edema, pneumothorax, pleural abnormalities, and respiratory-device position. CT provides high-resolutionanatomical information and can quantify regional lung aeration and structural disease, particularly in heterogeneous acute respiratory distress syndrome (ARDS). LUS provides radiation-free, repeatable bedside assessment of pleural and peripheral pulmonary abnormalities and has increasing evidence in acute respiratory failure, lung aeration assessment, and weaning. Emerging evidence also supports structured LUS education for RTs, although competency standards and longitudinal outcome data remain limited. Imaging should complement, rather than replace, clinical assessment and respiratory physiology. The most useful model is an integrated pathway in which imaging findings are interpreted alongside gas exchange, respiratory mechanics, ventilator waveforms, work of breathing, and treatment response. Quantitative CT, artificial intelligence, dynamic chest radiography, and electrical impedance tomography may further expand personalised imaging-guided respiratory care. Implementation should occur within local scope-of-practice, credentialing, and multidisciplinary governance frameworks.

Comparative Cytocompatibility and Morphological Assessment of Silver Nanoparticle Formulations in Human Dental Pulp Stem Cells

Mon, 19 Oct 2026 00:00:00 GMT

Comparative Cytocompatibility and Morphological Assessment of Silver Nanoparticle Formulations in Human Dental Pulp Stem Cells Manzanera-Mondéjar, Ángeles; Guerrero-Girones, Julia; Rivas-Mundina, Berta; García-Bernal, David; López-García, Sergio Objectives: This in vitro study evaluated the cytocompatibility and cellular response of human dental pulp stem cells (hDPSCs) exposed to two experimental polyethyleneimine/polyvinylpyrrolidone-stabilized silver nanoparticle formulations, MG-85 and MG-89. Methods: hDPSCs isolated from human third molars were treated with serial concentrations of both formulations. Cell metabolic activity and half-maximal inhibitory concentration (IC50) were assessed using the MTT assay. Wound closure was evaluated by wound-healing assay, while cytoskeletal organization and nuclear morphology were examined by phalloidin/DAPI fluorescence microscopy. Apoptosis/necrosis and intracellular reactive oxygen species production were analyzed by flow cytometry using Annexin V-FITC/7-AAD and CM-H2DCFDA, respectively. IL-6 release and IL-8 release were quantified by ELISA. Results: Both formulations induced concentration-dependent biological effects in hDPSCs. MG-89 showed a higher IC50 than MG-85 and preserved metabolic activity, wound closure, cytoskeletal organization, and nuclear morphology more effectively at low concentrations. At higher concentrations, both formulations impaired wound closure and altered cellular morphology, although these effects were more pronounced for MG-85. Flow cytometry showed increased apoptotic/necrotic populations at higher concentrations, particularly after MG-85 exposure. MG-85 also induced greater intracellular ROS production and higher IL-6/IL-8 release than MG-89. Conclusions: Within the limitations of this direct-exposure in vitro model, MG-89 exhibited a more favorable cytocompatibility profile than MG-85 in hDPSCs, particularly at low concentrations. These findings support the use of microscopy-based and multiparametric cellular assays for preclinical screening of AgNP-containing dental materials.

Effect of different enamel preconditioning protocols on the adhesion of ceramic brackets

Thu, 28 May 2026 00:00:00 GMT

Effect of different enamel preconditioning protocols on the adhesion of ceramic brackets Cendan, Lara; Bravo-González, Luis-Alberto; Ortiz-Ruiz, Antonio-José; Martínez-Beneyto, Yolanda; Vicente, Ascensión This study aimed to compare the adhesion of clarity advanced ceramic brackets bonded with APC Flash Free (APC FF) and Transbond XT (TXT) using different enamel conditioning protocols. Brackets were bonded to extracted bovine incisors, which were divided into 6 groups: (1) Transbond Plus Self Etching Primer (TSEP)/APC FF, (2) Etching/TSEP/APC FF, (3) Polishing/TSEP/APC FF, (4) TSEP/TXT, (5) Etching/TSEP/TXT and 6)Polishing/TSEP/TXT. Shear bond strength was measured using a universal testing machine. After debonding, each tooth was assigned an Adhesive Remnant Index score. The enamel was observed using a scanning electron microscope (SEM). The penetrability of TSEP and composites was determined using confocal microscopy. The bond strength of Etching/TSEP/TXT and Polishing/TSEP/TXT groups was significantly higher than that of the remaining groups, with Etching/TSEP/TXT being significantly higher than Polishing/TSEP/TXT (p < 0.05). With APC FF, there was a tendency for an increase in residual adhesive when etching and with TXT when polishing. SEM showed that etching produced the most porous enamel surface. For both APC FF and TXT bonded brackets, TSEP penetration was similar and significantly higher after etching (p = 0.000). APC FF and TXT had similar and significantly higher penetration in the etched groups (p = 0.000). Ceramic brackets bonded with TXT pre-etching the enamel before applying TSEP showed the most favourable adhesive characteristics.