Repositorio Dspace

Listar por tema "NF-kappa B/metabolism"

Listar por tema "NF-kappa B/metabolism"

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  • Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation 
    Santiago, Llipsy; Castro, Marta; Sanz-Pamplona, Rebeca; Garzon, Marcela; Ramírez-Labrada, Ariel; Tapia, Elena; Moreno, Víctor; Layunta, Elena; Gil-Gómez, Gabriel; Garrido, Marta; Pena, Raúl; Lanuza, Pilar-M; Comas, Laura; Jaime-Sánchez, Paula; Uranga-Murillo, Iratxe; del-Campo, Rosa; Pelegrín, Pablo; Camerer, Eric; Martínez-Lostao, Luis; Muñoz, Guillermo; Uranga, José-A; Alcalde, Anabel; Gálvez, Eva-M; Ferrandez, Ángel; Bird, Phillip; Metkar, Sunil; Arias, Maykel-A; Pardo, Julián (CELL PRESS, 2020-07)
    If not properly regulated, the inflammatory immune response can promote carcinogenesis, as evident in colorectal cancer (CRC). Aiming to gain mechanistic insight into the link between inflammation and CRC, we perform ...
  • Pacritinib prevents inflammation-driven myelofibrosis-like phenotype in a miR-146a-/- murine model 
    Cuenca-Zamora, Ernesto-José; Martínez, Constantino; Morales, María-Luz; Guijarro-Carrillo, Pedro-Jesús; López-Poveda, María-José; Alcolea-Guardiola, Carlos; Vidal-Garrido, Natalia; Lozano-Almela, María-Luisa; González-Conejero, Rocío; Teruel-Montoya, Raúl; Ferrer-Marín, Francisca (Elsevier Masson s.r.l., 2024)
    Chronic proinflammatory signaling is a characteristic trait in myeloproliferative neoplasms (MPN), particularly myelofibrosis (MF). Aberrant inflammatory signaling, particularly from NF-?B pathway, exacerbates the progression ...
  • Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4 
    Pizzuto, Malvina; Lonez, Caroline; Baroja-Mazo, Alberto; Martínez-Banaclocha, Helios; Tourlomousis, Panagiotis; Gangloff, Monique; Pelegrín, Pablo; Ruysschaert, Jean-Marie; Gay, Nicholas-J; Bryant, Clare-E (SPRINGER BASEL AG, 2019-09)
    Cardiolipins (CLs) are tetra-acylated diphosphatidylglycerols found in bacteria, yeast, plants, and animals. In healthy mammals, CLs are unsaturated, whereas saturated CLs are found in blood cells from Barth syndrome ...