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  • Expert Opinion and Evidence-Based Review on Maintenance Therapy Step-Down in Patients With Severe Asthma Controlled With Biologics. 
    Plaza, Vicente; Soto-Campos, Gregorio; Miralles-López, Juan-Carlos; Padilla-Galo, Alicia; Martínez-Moragon, Eva; Rodríguez, Fernando; Mosteiro, Mar; Ausin, Pilar; Cebollero, Pilar; Quirce, Santiago; Almonacid, Carlos (ELSEVIER, 2026-04)
    INTRODUCTION: Severe asthma (SA) management requires a comprehensive, individualized approach with continuous pharmacological treatment adjustments. In SA patients controlled with biologics, decisions on how to adjust ...
  • Expert panel consensus recommendations for diagnosis and treatment of secondary osteoporosis in children 
    Galindo-Zavala, Rocío; Bou-Torrent, Rosa; Magallares-López, Berta; Mir-Perelló, Concepción; Palmou-Fontana, Natalia; Sevilla-Pérez, Belén; Medrano-San-Ildefonso, Marta; González-Fernández, María-Isabel; Román-Pascual, Almudena; Alcañiz-Rodríguez, Paula; Nieto-González, Juan-Carlos; López-Corbeto, Mireia; Granã-Gil, Jenaro (BioMed Central Ltd., 2020)
    BACKGROUND: Osteoporosis incidence in children is increasing due to the increased survival rate of patients suffering from chronic diseases and the increased use of drugs that can damage bones. Recent changes made to the ...
  • Expert recommendations about the use of gadoxetic acid in patients with liver metastases in Spain 
    Borrego-Gómez, J; Romera, N; Tellado, JM; del-Campo, L; Díaz-Formoso, J; Fuster, M; Vivas, I; Ramón-Botella, E; Menéndez-de-Llano-Ortega, R (ELSEVIER ESPANA, 2022-07)
    BACKGROUND AND AIMS: Magnetic resonance imaging (MRI) with gadoxetic acid is widely used in clinical practice in Spain for the diagnosis, treatment, and follow-up of patients with liver metastases, although its use varies. ...
  • Expert recommendations on the management of patients with metastatic castration-resistant prostate cancer who progress after CHAARTED or LATITUDE 
    Puente, Javier; Anido, Javier-C; Climent, Miguel-Ángel; González-Billalabeitia, Enrique; Lainez, Nuria; Lambea, Julio; Maroto, José-Pablo; Méndez-Vidal, María-José; Montesa, Álvaro; Rodríguez, Ángel; Zambrana, Curro; González-del-Alba, Aranzazu (SAGE PUBLICATIONS LTD, 2020-05)
    OBJECTIVE: Our aim was to provide practical recommendations on the management of patients with metastatic castration-resistant prostate cancer (mCRPC) who have progressed after docetaxel plus androgen-deprivation therapy ...
  • Expert Revision of Key Elements for Clinical-Grade Production and Qualification of Perinatal Derivatives 
    Gramignoli, Roberto; Hofmann, Nicola; Agudo-Barriuso, Marta; Antica, Maríastefania; Flores, Ana; Girandon, Lenart; Kerdjoudj, Halima; Navakauskiene, Ruta; Schiavi, Jessica; Scholz, Hanne; Shablii, Volodymyr; Lafarge, Xavier; Nicolás, Francisco-José; Gindraux, Florelle (OXFORD UNIV PRESS, 2024-01-12)
    Perinatal derivatives have been proposed as adjunct therapeutic strategies or innovative treatments. Undoubtedly, perinatal derivatives can offer the opportunity and source material to isolate multipotent stem cells, but ...
  • Explainable artificial intelligence prediction-based model in laparoscopic liver surgery for segments 7 and 8: an international multicenter study 
    López-López, Víctor; Morise, Zeniche; Albadalejo-González, Mariano; Gómez-Gavara, Concepción; Goh, Brian-KP; Koh, Ye-Xin; Paul, Sijberden-Jasper; Hilal, Mohammed-Abu; Mishima, Kohei; Kruerger, Jaime-Arthur-Pirola; Herman, Paulo; Cerezuela, Álvaro; Brusadin, Roberto; Kaizu, Takashi; Luján, Juan; Rotellar, Fernando; Monden, Kazuteru; Dalmau, Mar; Gotohda, Naoto; Kudo, Masashi; Kanazawa, Akishige; Kato, Yutaro; Nitta, Hiroyuki; Amano, Satoshi; Valle, Raffaele-Dalla; Giuffrida, Mario; Ueno, Masaki; Otsuka, Yuichiro; Asano, Daisuke; Tanabe, Minoru; Itano, Osamu; Minagawa, Takuya; Eshmuminov, Dilmurodjon; Herrero, Irene; Ramírez, Pablo; Ruiperez-Valiente, José-A; Robles-Campos, Ricardo; Wakabayashi, Go (Springer, 2024-04)
    BACKGROUND: Artificial intelligence (AI) is becoming more useful as a decision-making and outcomes predictor tool. We have developed AI models to predict surgical complexity and the postoperative course in laparoscopic ...
  • Exploratory case-control study on childhood cancer near the Mar Menor lagoon Region of Murcia (Spain) 2000 to 2018 
    Ojeda-Sánchez, Carlos; Ramis, Rebeca; Fernández-Avilés, Gema; Díaz-Martínez, Francisco; Orenes-Piñero, Esteban; Ortega-García, Juan-Antonio (BMC, 2024-07)
  • Exploratory Cost-Effectiveness of a Novel Bioprosthetic Valve for Surgical Aortic Valve Replacement in Spain 
    Ascaso, María; Pérez, Daniel; Montero, Lourdes; Deckert, Jens; White, Andrea; González, Paloma; Mengual, Marta; Lorenzo-Herrero, Seila; Crespo, Carlos; Cánovas-López, Sergio (SPRINGER INT PUBL AG, 2025-09)
    OBJECTIVES: Limited information is available regarding the impact of valve choice for patients with aortic stenosis (AS) undergoing surgical aortic valve replacement (SAVR) in Spain. Herein, we aimed to explore the potential ...
  • EXPLORE B: A prospective, long-term natural history study of patients with acute hepatic porphyria with chronic symptoms 
    Cassiman, David; Kauppinen, Raili; Monroy, Susana; Lee, Ming-Jen; Bonkovsky, Herbert-L; Thapar, Manish; Guillén-Navarro, Encarna; Minder, Anna-Elisabeth; Hale, Cecilia; Sweetser, Marianne-T; Ivanova, Aneta (Wiley, 2022-11)
    One-year data from EXPLORE Part A showed high disease burden and impaired quality of life (QOL) in patients with acute hepatic porphyria (AHP) with recurrent attacks. We report baseline data of patients who enrolled in ...
  • Exploring association of melanoma-specific Bcl-xL with tumor immune microenvironment 
    Lucíano, Anna-María; Di-Martile, Marta; Pérez-Oliva, Ana-Belén; Di-Caprio, Marica; Foddai, María-Laura; Buglioni, Simonetta; Mulero, Victoriano; del-Bufalo, Donatella (BMC, 2023-07)
    BACKGROUND: Macrophages take center stage in the tumor microenvironment, a niche composed of extracellular matrix and a heterogeneous group of cells, including immune ones. They can evolve during tumor progression and ...
  • Exploring Blue Spaces' Effects on Childhood Leukaemia Incidence: A Population-Based Case-Control Study in Spain 
    Ojeda-Sánchez, Carlos; García-Pérez, Javier; Gómez-Barroso, Diana; Domínguez-Castillo, Alejandro; Pardo-Romaguera, Elena; Canete, Adela; Ortega-García, Juan-Antonio; Ramis, Rebeca (MDPI, 2022-05)
    BACKGROUND: Blue spaces have been a key part of human evolution, providing resources and helping economies develop. To date, no studies have been carried out to explore how they may be linked to paediatric oncological ...
  • Exploring causality of the association between smoking and Parkinson's disease 
    Gallo, Valentina; Vineis, Paolo; Cancellieri, Mariagrazia; Chiodini, Paolo; Barker, Roger-A; Brayne, Carol; Pearce, Neil; Vermeulen, Roel; Panico, Salvatore; Bueno-de-Mesquita, Bas; Vanacore, Nicola; Forsgren, Lars; Ramat, Silvia; Ardanaz, Eva; Arriola, Larraitz; Peterson, Jesper; Hansson, Oskar; Gavrila-Chervase, Diana; Sacerdote, Carlotta; Sieri, Sabina; Kuehn, Tilman; Katzke, Verena-A; van-der-Schouw, Yvonne-T; Kyrozis, Andreas; Masala, Giovanna; Mattiello, Amalia; Perneczky, Robert; Middleton, Lefkos; Saracci, Rodolfo; Riboli, Elio (OXFORD UNIV PRESS, 2019-06)
    BACKGROUND: The aim of this paper is to investigate the causality of the inverse association between cigarette smoking and Parkinson's disease (PD). The main suggested alternatives include a delaying effect of smoking, ...
  • Exploring mechanisms of scar-free skin wound healing in adult zebrafish in comparison to mouse 
    Kucukaylak, Ismail; Halwas, Kai; Martínez-Morcillo, Francisco-Javier; Reiche, Nils; Metzger, Manuel; Comelli, Petra; Voigt, Birgit; Brinckmann, Jurgen; Eming, Sabine; Hammerschmidt, Matthias (PUBLIC LIBRARY SCIENCE, 2026-06-24)
    Adult zebrafish have the ability to perfectly regenerate their skin after injury without leaving a scar behind. Yet, they intermediately form a collagen-rich granulation tissue that later fully regresses. In contrast, adult ...
  • Exploring nurses' experiences with a school-located influenza vaccination program: A qualitative study in the region of Murcia, Spain 
    Perez Martin, Jaime; Zornoza Moreno, Matilde; Martinez Ruiz, Marina; Robles Manueco, Marta (TAYLOR & FRANCIS INC, 2025-12-31)
    A cross-sectional qualitative pilot study was designed to assess the nurses' perspectives regarding a school-located influenza vaccination pilot program. The program was developed during the 2022-2023 season in the Region ...
  • Exploring Structure-Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates 
    Rovira, Anna; Ortega-Forte, Enrique; Hally, Cormac; Jorda-Redondo, Mireia; Abad-Montero, Diego; Vigueras, Gloria; Martínez, Jesús-I; Bosch, Manel; Nonell, Santi; Ruiz, José; Marchan, Vicente (AMER CHEMICAL SOC, 2023-06)
    Photodynamic therapy holds great promise as a non-invasive anticancer tool against drug-resistant cancers. However, highly effective, non-toxic, and reliable photosensitizers with operability under hypoxic conditions remain ...
  • Exploring the Immunoresponse in Bladder Cancer Immunotherapy 
    Ruiz-Lorente, Inmaculada; Gimeno, Lourdes; López-Abad, Alicia; López-Cubillana, Pedro; Fernández, Aparicio; Asensio-Egea, Lucas-Jesús; Moreno-Avilés, Juan; Donate-Iñíguez, Gloria; Guzmán-Martínez-Valls, Pablo-Luis; Server-Gómez, Gerardo; Escudero-Bregante, José-Félix; Ferri, Belén; Campillo, José-Antonio; Pons-Fuster, Eduardo; Martínez-Hernández, María-Dolores; Martínez-Sánchez, María-Victoria; Ceballos, Diana; Minguela-Puras, Alfredo (MDPI, 2024-12)
    Bladder cancer (BC) represents a wide spectrum of diseases, ranging from recurrent non-invasive tumors to advanced stages that require intensive treatments. BC accounts for an estimated 500,000 new cases and 200,000 deaths ...
  • Exploring the Relation between Atopic Diseases and Lifestyle Patterns among Adolescents Living in Greece: Evidence from the Greek Global Asthma Network (GAN) Cross-Sectional Study 
    Antonogeorgos, George; Priftis, Kostas-N; Panagiotakos, Demosthenes-B; Ellwood, Philippa; García-Marcos, Luis; Liakou, Evangelia; Koutsokera, Alexandra; Drakontaeidis, Pavlos; Moriki, Dafni; Thanasia, Marina; Mandrapylia, María; Douros, Konstantinos (MDPI, 2021-10)
    INTRODUCTION: Diet and physical activity might be associated with the risk of allergic diseases in childhood. However, evidence in literature is sparse and diverse. We aim to examine the associations between four healthy ...
  • Exploring the utility of Preevid, an evidence-based answer service to clinical questions, during the COVID-19 pandemic 
    Rosa-Garcia, Concepcion; Mas-Bleda, Amalia; Moreno-Pina, Josefa Patricia; Pozo-Serrano, Isabel; Sanchez-Lopez, Maria del Carmen; Sanchez-Sanchez, Juan Antonio; Aguinaga-Ontoso, Enrique (WILEY, 2025-09)
    BACKGROUND: Clinical question services offer evidence-based relevant clinical information allowing health professionals to obtain answers in a timely manner. OBJECTIVES: To explore the use and usefulness of Preevid, an ...
  • Exploring the Variability in Antibacterial Testing of Resin Dental Composites among Investigators: A Narrative Review 
    Pal, Ashlesha; Altaf, Noorulain; Mahmood, Anum; Akbar, Shazia; Maher, Nazrah; Kumar, Naresh; Zafar, Muhammad-Sohail; Murcia, Laura; Oñate-Sánchez, Ricardo-Elías (MDPI, 2023-12)
  • Exploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence 
    Ojeda-Sánchez, Carlos; García-Pérez, Javier; Gómez-Barroso, Diana; Domínguez-Castillo, Alejandro; Pardo-Romaguera, Elena; Cañete, Adela; Ortega-García, Juan-Antonio; Ramis, Rebeca (MDPI, 2023)
    BACKGROUND: Several environmental factors seem to be involved in childhood leukaemia incidence. Traffic exposure could increase the risk while urban green spaces (UGS) exposure could reduce it. However, there is no evidence ...