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  • Sacubitril-Valsartan, Clinical Benefits and Related Mechanisms of Action in Heart Failure With Reduced Ejection Fraction. A Review 
    Pascual-Figal, Domingo-A; Pascual-Figal, Domingo-A; Bayés-Genís, Antoni; Beltrán-Troncoso, Paola; Caravaca-Pérez, Pedro; Conde-Martel, Alicia; Crespo-Leiro, María-G; Delgado, Juan-F; Díez, Javier; Formiga, Francesc; Manito, Nicolas (FRONTIERS MEDIA SA, 2021-11)
    Heart failure (HF) is a clinical syndrome characterized by the presence of dyspnea or limited exertion due to impaired cardiac ventricular filling and/or blood ejection. Because of its high prevalence, it is a major health ...
  • Sacubitril/valsartan affects pulmonary arterial pressure in heart failure with preserved ejection fraction and pulmonary hypertension 
    Codina, Pau; Domingo, Mar; Barceló, Elena; Gastelurrutia, Paloma; Casquete, Daniel; Vila, Joan; Abdul-Jawad-Altisent, Omar; Spitaleri, Giosafat; Cediel, German; Santiago-Vacas, Evelyn; Zamora, Elisabet; Ruiz-Cueto, María; Santesmases, Javier; de-la-Espriella, Rafael; Pascual-Figal, Domingo-A; Núñez, Julio; Lupon, Josep; Bayés-Genís, Antoni (Wiley Periodicals, Inc, 2022-08)
    AIMS: Prior studies have not fully characterized the haemodynamic effects of the angiotensin receptor-neprilysin inhibitor (ARNI) sacubitril/valsartan in heart failure with preserved ejection fraction and pulmonary ...
  • Safe and transparent introduction and evaluation of targeted axillary dissection in patients with node-positive breast cancer undergoing primary surgery: International consensus process 
    Potter, Shelley; Mullan, Ruth; Cain, Henry; St-John, Edward-R; Barry, Peter; Massanat, Yazan; Harvey, James; Fairhurst, Katherine; Morgan, Adrienne; Perkins, Margaret; Mann, Gregory-Bruce; Lippey, Jocelyn; Cowan, Katherine; Blencowe, Natalie; McIntosh, Stuart-A; Avery, Kerry; Baji, Petra; Bhattacharya, Indrani; Cutress, Ramsey; Culliford, Lucy; Dodwell, David; Frost, Jessica; Harris, Jessica; Markham, Hannah; Marques, Elsa; Roberts, Kirsty; Rees, Sophie; Aamer, Mohamed; Abbott, Nick; Abdelaziz, Youmna; Abdelwahab, Khaled; Abdulla, Hussain; Abufkhaida, Belal; Agrawal, Avi; Ahmad, Zarka; Ali-Ahmed, Mohamed-Sherif; Ahmed, Shabir; Saad, Suhair-A-L; Alhussini, Mahmoud; Alriyees, Lolwah; Alshawi, Jeha; Aslam, Maila; Attia, Mohamed; Awaji, Kholoud; Baban, Chwanrow; Bagué, Abdoul-Halim; Bajonero-Canonico, Paulina; Ba?türk, Seda-Arzuman; Bibal, Faisal; Bolivar, Efren; Bramley, María; Brown, Victoria; Buldanli, Mehmet-Zeki; Canotilho, Rita; Carbonell-Luna, María-Isabel; Carmichael, Amtul-R; Caziuc, Alexandra; Chan, Ching-Wan; Chand, Natalie; Chandrashekar, Mysore; Chaubey, Arun; Chen, Samantha; Daskalova, Iskra; Dimitrov, Dobromir; Dordea, Matei; Douvetzemis, Stergios; Elahi, Mohammad; Elder, Kenneth; Elsberger, Beatrix; Elzein, Sahar; Fanshawe, Ángela; Félix, Rosa; Fowler, Clare; Gallini, Elena; Gan, Joan; Garg, Nidhi; Georgescu, Rares; Ghazali, Wafaa; Ginghina, Octav; Godden, Amy-R; Gomez-Quiñones, Omar; Graham, Victoria; Gul, Melih-Can; Hançerlio?ullari, O?uz; Harding-Mackean, Claudia; Hargreaves, Anita; Harris, Grant; Hartley, Frederick; Hassan, Iram; Hayat, Saddaqat; Holcombe, Christopher; Horsnell, Jonathan; Hubbard, Thomas; Hunter-Smith, Alison; Ikram, Rabia; Irvine, Tracey; Irwin, Gareth; Isherwood, Jen; Isik, Arda; Islam, Sharmin; Jaber, Abdulrhman; Jauhari, Yasmin; Jiménez-Gómez, Marta; Johri, Goonj; Kallaway, Charlotte; Kamer, Kemal-Erdinc; Cakmak, Guldeniz-Karadeniz; Karakullukcu, Haluk-Kerim; Karamanliev, Martin; Karwasra, Isha; Karydakis, Vasileios; Kaushik, Monika; Khan, Mah-Muneer; Khout, Hazem; Kirk, Stephen; Kirwan, Cliona-Clare; Kitsikosta, Loukiani; Kiziltoprak, Nurhilal; Knight, Hannah; Köksal, Hande; Krsicka, Petr; Krupa, Katherine; Krupa, Jaroslaw; Kucuk, Gultekin-Ozan; Lane, Risha; Laws, Siobhan; Lefemine, Valentina; Lipp-Von-Wattenwyl, Begonia; López-Rodríguez, María-Jesús; Lowery, Aoife; Lubis, Mhd-Zuhri-Nanda-Rizki; MacInnes, Emma; Mandi, Draga; Mantoglu, Baris; Marques-Lauria, Patricia; Martin, Lee; De-Jesús-Martins-Dias, Teresa; Massey, Eleanore; Masudi, Tahir; Mathers, Helen; McLean, Ross; Memi?, Ufuk; Memi?o?lu, Ecem; Merker, Louise; Micha, Aikaterini; Michalakis, Ioannis; Jan, María-Mir; Mitchell, Geraldine; Mohammed, Fatima; Mondal, Radha-Raman; Morgan, Jenna; Muktar, Samantha; Mullan, Michelle; Murphy, Claire; Naqvi, Syeda-Rifaat-Qamar; Naz, Saman; Lakshmi, Harish-Neelamraju; O'Connell, Rachel-L; Octavian, Enciu; Odofin, Bunmi; Olsen, Sisse; Omidiji, Olubukola; Osman, Hisham; Ozkan, Omer-Faruk; Papadopoulos, Lazaros; Peerlinck, Inge; Pereira, Helena; Pilgrim, Simon; Piñero-Madrona, Antonio; Polotto, Susanna; Prusty, Lydia; Ramzi, Saed; Rapisarda, Fabio; Rathinaezhil, Rathi; Rattay, Tim; Rees-Lee, Jacqueline; Resendiz-Colosia, Jaime-Alonso; Ribeiro, Catia; Rocco, Nicola; Roche, Nicola; Rodrigues, Fabio; Rohr, Matthias; Romics, Laszlo; Rowland, Matthew; Rusby, Jennifer; Saha, Sunita; Sajid, Yasmeen; Salman, Reem; Sami, Amtul-Shafee; Martín-Sánchez, Alejandro; Sánchez-Méndez, José-I; Sanli, Ahmet-Necati; Scally, Norah; Scardina, Lorenzo; Sciamannini, María; Shafique, Natasha; Sheehan, Lisa; Shetty, Spoorthi; Shoshkova, Meri; Simpson, Duncan; Skelly, Brendan-L; Stanton, Roslyn; Mandal, Nishith-Sudhir; Tasoulis, Marios-Konstantinos; Taylor, Amanda; Thakur, Natasha; Thomas, Rob; Thorat, Mangesh; Thorne, Amanda; Timbur, Dragomir; Townend, Alice; Trabulsi, Nora; Tuffaha, Hussein; Uçaner, Burak; Valassiadou, Kalliope; Vassos, Nikolaos; Vatish, Jamie; Vernet-Tomas, María; Verroiotou, María; Wilson, Rebecca-L; Yesilsancak, Merve; Yiallourou, Anneza; Yildirim, Ali-Cihat; Yotsov, Tsanko; Zammit, Charles; Zuñiga-Vázquez, Luis-Abraham (Oxford University Press, 2025-10-30)
    BACKGROUND: Axillary node clearance is the current standard of care in patients with node-positive breast cancer undergoing primary surgery, despite a lack of evidence to demonstrate survival benefit and high rates of ...
  • Safe Care in Childhood and Adolescence Under Guardianship: Contributions From Attachment Theory 
    Lacasa-Saludas, Fernando; Rodado-Martínez, María-Jose; Sadurni-Brugue, Marta; Folch-Naya, Beatriz; Fernández-Mayoralas, Irene (CONSEJO GENERAL PSICOLOGIA DE ESPANA, 2025)
  • Safety and Effectiveness From the Cabotegravir and Rilpivirine Implementation Study in European Locations Study: Phase 3b Hybrid Type III Implementation Study Integrating Cabotegravir plus Rilpivirine Long-Acting Into European Clinical Settings 
    Jonsson-Oldenbuettel, Celia; Ghosn, Jade; van-der-Valk, Marc; Florence, Eric; Vera, Francisco; De-Wit, Stephane; Rami, Agathe; Bonnet, Fabrice; Hocqueloux, Laurent; Hove, Kai; Ait-Khaled, Mounir; DeMoor, Rebecca; Bontempo, Gilda; Latham, Christine-L; Gutner, Cassidy-A; Iyer, Supriya; Gill, Martín; Czarnogorski, Maggie; D'Amico, Ronald; van-Wyk, Jean (LIPPINCOTT WILLIAMS & WILKINS, 2024-08-15)
    BACKGROUND: Cabotegravir + rilpivirine long-acting (CAB + RPV LA) dosed every 2 months (Q2M) is a complete regimen for the maintenance of HIV-1 virologic suppression. In this study, we report month 12 clinical outcomes in ...
  • Safety and Effectiveness of Percutaneous Ultrasound-Guided Galvanic Current in Tunnels of Patients with Hidradenitis Suppurativa: A Pilot Study 
    Soto-Moreno, Alberto; Cuenca-Barrales, Carlos; Arias-Santiago, Salvador; García-Vidal, José-Antonio; Medina-Mirapeix, Francesc; Molina-Leyva, Alejandro (ADIS INT LTD, 2024-05)
    INTRODUCTION: The recurrent nature of hidradenitis suppurativa (HS), even under maintained systemic treatment, makes it necessary to have effective local treatments; however, the response to these therapies is variable ...
  • Safety and Effectiveness of Subcutaneous Immunotherapy with a Glutaraldehyde-Polymerized Mite Allergen Extract in Adults and Children with Allergic Rhinitis with or Without Asthma Due to Dermatophagoides 
    Verdeguer-Segarra, Olalla; Almeida-Sánchez, Zulay; Quarta, Silvia; Funes-Vera, Emilio; González-Jiménez, Oscar-M; Hernández-Santana, Guacimara; Herrero-Lifona, Leticia; López-González, Paula; Martínez-Gomariz, Montserrat; López-Cauce, Beatriz; Gómez-Cardeñosa, Aida (MDPI, 2026-01-23)
    BACKGROUND/OBJECTIVES: The aim of this study was to evaluate the tolerability and effectiveness of subcutaneous immunotherapy (SCIT) in allergic adults and children treated with a polymerized-glutaraldehyde undiluted mixture ...
  • Safety and Effectiveness of Volumetric Modulated Arc Therapy-Based Stereotactic Radiosurgery for Posterior Fossa Brain Metastases: A Single-Centre Experience 
    Sánchez-Villalobos, José-Manuel; Serna-Berna, Alfredo; Salinas-Ramos, Juan; Escolar-Pérez, Pedro-Pablo; Luengo-Gil, Ginés; Andreu-Gálvez, Marina; Martínez-Alonso, Emma; Alcaraz, Miguel (MDPI, 2025-12-02)
    Background/Objectives: Posterior fossa brain metastases (PFBMs) pose particular risks owing to their proximity to the brainstem and fourth ventricle. We evaluated the safety (treatment-related complications), local ...
  • Safety and efficacy of asciminib treatment in chronic myeloid leukemia patients in real-life clinical practice 
    García-Gutiérrez, Valentín; Luna, Alejandro; Alonso-Domínguez, Juan-Manuel; Estrada, Natalia; Boque, Concepción; Xicoy, Blanca; Giraldo, Pilar; Angona, Anna; Álvarez-Larrán, Alberto; Sánchez-Guijo, Fermín; Ramírez, María-José; Mora, Elvira; Vélez, Patricia; Rosell, Ana; Colorado-Araujo, Mercedes; Cuevas, Beatriz; Sagüés, Miguel; Cortés, Montserrat; Pérez-Encinas, Manuel-Mateo; Casado-Montero, Luis-Felipe; Moreno-Vega, Melania; Serrano, Luis; Gómez, Valle; García-Hernández, Carmen; Lakhwani, Sunil; Paz-Coll, Antonio; de-Paz, Raquel; Suárez-Varela, Sara; Fernández-Ruiz, Andrés; Pérez-López, Raúl; Ortiz-Fernández, Almudena; Jiménez-Velasco, Antonio; Steegmann-Olmedillas, Juan-Luis; Hernández-Boluda, Juan-Carlos (Springer Nature, 2021)
  • Safety and Efficacy of BioMime Sirolimus-Eluting Stent System in All-Comers Real-World Population With Coronary Artery Stenosis: MILES Global Registry 
    Hudec, Martín; Jeong, Myung-Ho; Trillo, Ramiro; Ijsselmuiden, Alexander-JJ; Gwon, Hyeon-Cheol; Chae, In-Ho; Wang, Yi-Chih; Marqués-de-Costa, José-Manuel; Charng, Min-Ji; Maskon, Oteh; Moreu-Burgos, José; Mayurathan, Gnanamoorthy; Mateev, Hristo; Serra, Antonio; Merkely, Bela; Cale, Rita; Hwang, Shinn-Jang; Mar, Guang-Yuan; Lawand, Samih; Khokhlov, Andriy; Vaquerizo-Montilla, Beatriz; Valdes, Mariano; Sadeghian, Mohammad (ELMER PRESS INC, 2024-12)
    BACKGROUND: This study evaluated the safety and efficacy of BioMime sirolimus-eluting stent (SES) system, with an ultra-low strut thickness (65 µm), in real-world all-comers population with coronary artery stenosis (CAD). ...
  • Safety and efficacy of self-administered inhaled loxapine (ADASUVE) in agitated patients outside the hospital setting: protocol for a phase IV, single-arm, open-label trial 
    Gil, Emilio; García-Alonso, Fernando; Boldeanu, Anca; Teixeira, Thais-Baleeiro; Tordera, Vicente; Palmer-Viciedo, Ramon; Salgado, Purificacion; Domingo-Ribas, Jordi; Corripio-Collado, Iluminada; Montes, José-Manuel; Correas-Lauffer, Javier; Ruiz-Murugarrem, Salvador; Ovejero-García, Santiago; Mora, Fernando; López, Ataz; Fontalba-Navas, Andrés; González-Pinto, Ana-María; Martínez, Ricardo; García-Castrillo, César; Toledo, Francisco; Vieta, Eduard; González, Emilio; Franco, Manuel; Virgil-Drasovean, Nicolae; Havard-Dahl, Nils; Skagen, Bo; Zilles, David; Zwanzger, Peter; Juckel, Georg; Kahl, Kai-G; Messer, Thomas; Kasper, Siegfried (BMJ PUBLISHING GROUP, 2018-10)
    INTRODUCTION: There is a need for fast-acting, non-injection antiagitation treatments that are well tolerated and can be used outside of healthcare facilities. In phase II/III trials, an inhaled formulation of loxapine ...
  • SAFETY AND REVISIT RELATED TO DISCHARGE THE SIXTY-ONE SPANISH EMERGENCY DEPARTMENT MEDICAL CENTERS WITHOUT HOSPITALIZATION IN PATIENTS WITH COVID-19 PNEUMONIA. A PROSPECTIVE COHORT STUDY UMC-PNEUMONIA COVID-19 
    Jacob, Javier; Albert-Casado, Arantxa; del-Castillo, Juan-G; Llorens-Soriano, Pere; Jiménez-Hernández, Sonia; Burillo-Putze, Guillermo; Martín-Martínez, Alfonso; Martín-Sánchez, Francisco-Javier; García-Lamberechts, Eric-Jorge; Piñera-Salmerón, Pascual; Piñera-Salmerón, Pascual; Alquézar-Arbé, Aitor; Ferre-Losa, Carles; Juan-Gómez, María-Ángeles; Serrano-Lázaro, Leticia; Noceda-Bermejo, José; Salido-Mota, Manuel; Fortuny-Bayarri, María-J; González-Tejera, Matilde; Ferreras-Amez, José-M; Díaz-Fernández, Elena; Quero-Motto, Eva; Peiro-Gómez, Ana; Martín-Mojarro, Enrique; Llopis-Roca, Ferrán; Huerta-García, Arturo; Pedraza-García, Jorge; Meléndez-Calix, Napoleón; Brazo-Aznar, José; Cano-Cano, María-J; Miró, Óscar (INST NACIONAL NUTRICION, 2022-05)
    BACKGROUND: Information is needed on the safety and efficacy of direct discharge from the emergency department (ED) of patients with COVID-19 pneumonia. OBJECTIVES: The objectives of the study were to study the variables ...
  • Safety incidents in pediatric emergency departments: Incidence, characteristics, and variability between centers. A national multicenter study 
    Beteta-Fernández, María-Dolores; Pérez-Cánovas, Carlos; Martínez-Egea, Rosa-Belén; Alcaraz-Martínez, Julián; De-Souza-Oliveira, Adriana-Catarina; Pardo-Ríos, Manuel; Grupo-de-Trabajo-RISeuP-SPERG (EDICIONES DOYMA S A, 2025-10)
  • Safety incidents in pediatric emergency departments: Incidence, characteristics, and variability between centers. A national multicenter study. 
    Beteta-Fernández, Dolores; Pérez-Cánovas, Carlos; Martínez-Egea, Rosa-Belen; Alcaraz-Martínez, Julian; De-Souza-Oliveira, Adriana-Catarina; Pardo-Ríos, Manuel (ELSEVIER, 2025-10)
    INTRODUCTION: Pediatric emergency departments are high-risk environments for patient safety due to the workload, time pressure and clinical vulnerability of the population. However, there is limited evidence regarding the ...
  • Safety of indocyanine green for lymph node mapping in early-stage vulvar cancer: multicenter evaluation and systematic review 
    Guijarro-Campillo, Alberto-Rafael; Padilla-Iserte, Pablo; Couso, Bárbara; Erasun, Diego; Utrilla-Layna, Jesús; Arencibia, Octavio; Gilabert-Estelles, Juan; Veiga, Nadia; Boldo-Roda, Ana; Lago, Victor; Nieto-Díaz, Aníbal; Domingo, Santiago (SPRINGERNATURE, 2026-01-14)
    PurposeThis study aimed to evaluate the rate and severity of allergic events associated with the use of indocyanine green (ICG) in sentinel lymph node biopsy (SLNB) for patients with early-stage vulvar cancer. The research ...
  • Safety of Post-Transplant Cyclophosphamide-Based Prophylaxis in AML Patients with Pre-Existing Cardiac Morbidity Undergoing Allogeneic Hematopoietic Cell Transplantation 
    Torrent-Rodríguez, Arnau; Cascos, Enric; Garces, Víctor-Navarro; Pérez-López, Estefanía; Baile-González, Mónica; Martín-Rodríguez, Carlos; Pascual-Cascon, María-Jesús; Luque, Marta; Esquirol, Albert; Martín-Calvo, Carmen; Peña-Muñoz, Felipe; Heras-Fernando, Inmaculada; Oiartzabal-Ormategi, Itziar; Sáez-Marin, Adolfo-Jesús; Fernández-Luis, Sara; Domínguez-García, Juan-José; Villar-Fernández, Sara; López-Lorenzo, José-Luis; Fernández-de-Sanmamed-Girón, Miguel; González-Pinedo, Leslie; García-Mano, Lucía; González-Rodríguez, Ana-Pilar; Torrado, Tamara; Filaferro, Silvia; Basalobre, Pascual; Orti, Guillermo; Rovira, Montserrat; Jurado-Chacón, Manuel; Queralt-Salas, María (MDPI, 2025-09-26)
    BACKGROUND: Post-transplant cyclophosphamide (PTCy) is a standard graft-versus-host disease (GVHD) prophylaxis in allogeneic hematopoietic cell transplantation (allo-HCT). While effective, concerns remain about ...
  • Safety of propofol sedation administered by an endoscopy team for outpatient colonoscopy 
    Del-Val-Oliver, Blanca; González-Valverde, Francisco-Migue; Del-Valle-Ruiz, Sergio-Rodrigo (ARAN Ediciones S.A., 2021)
    Sedation during colonoscopy increases comfort and reduces unexpected patient movement. Colorectal cancer (CRC) screening colonoscopies performed under propofol sedation controlled by our endoscopy team (ET) were retrospectively ...
  • Safety, activity, and molecular heterogeneity following neoadjuvant non-pegylated liposomal doxorubicin, paclitaxel, trastuzumab, and pertuzumab in HER2-positive breast cancer (Opti-HER HEART): an open-label, single-group, multicenter, phase 2 trial 
    Gavila, Joaquín; Oliveira, Mafalda; Pascual, Tomas; Pérez-García, José; González, Xavier; Canes, Jordi; Pare, Laia; Calvo, Isabel; Ciruelos, Eva; Muñoz, Montserrat; Virizuela, Juan-A; Ruiz, Isabel; Andrés, Raquel; Perello, Antonia; Martínez-García, Jerónimo; Morales, Serafin; Marín-Aguilera, Mercedes; Martínez, Debora; Quero, Juan-C; Llombart-Cussac, Antonio; Prat, Aleix (BMC, 2019-01-09)
  • Sagittal spinal morphotype assessment in 8 to 15 years old Inline Hockey players 
    Sainz-de-Baranda, Pilar; Cejudo, Antonio; Moreno-Alcaraz, Victor-Jesús; Martínez-Romero, María-Teresa; Aparicio-Sarmiento, Alba; Santonja-Medina, Fernando (PEERJ INC, 2020-01-02)
    BACKGROUND: Physiological sagittal spinal curvatures play an important role in health and performance in sports. For that reason, several scientific studies have assessed spinal morphology in young athletes. However, to ...
  • Saharan Dust Modeling Over the Mediterranean Basin and Central Europe: Does the Resolution Matter? 
    Palacios-Pena, Laura; Lorente-Plazas, Raquel; Montavez, Juan-Pedro; Jiménez-Guerrero, Pedro (FRONTIERS MEDIA SA, 2019-11-08)